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  1. Article ; Online: A 10-Year Study of the Trend of Accidental Falls in the Elderly in a Japanese Hospital.

    Takekawa, Toru / Obuchi, Kei / Watanabe, Shu / Yamada, Naoki / Abo, Masahiro

    Zeitschrift fur Orthopadie und Unfallchirurgie

    2024  

    Abstract: Elderly people are prone to falls. We established the Falls Prevention Working Group (FPWG) at our hospital in 2015 to reduce the number of falls during hospitalization. This study compared the trend of in-hospital falls in the elderly in two time ... ...

    Title translation Eine 10-Jahres-Studie über die Entwicklung von Sturzunfällen bei älteren Menschen in einem japanischen Krankenhaus - Empfehlungen multidisziplinärer Teams zur Reduzierung von Stürzen bei älteren Menschen.
    Abstract Elderly people are prone to falls. We established the Falls Prevention Working Group (FPWG) at our hospital in 2015 to reduce the number of falls during hospitalization. This study compared the trend of in-hospital falls in the elderly in two time periods (2008/9 and 2018/9) and determined the effects of FPWG-implemented measures. Using medical records, we counted the monthly number of falls suffered by patients during hospitalization in April 2008-March 2009 and April 2018-March 2019. We also categorized the falls according to the severity of fall-related complications.A total of 3609 hospital falls were recorded during the 2008-2019 period (2008/9: n = 433, 2018/9: n = 324). Falls were more common in patients aged 70-79 in 2008/9 but were noted in those aged ≥ 80 in 2018/9. The mean number of falls/month (27.3 ± 6.4, range: 12-45) was stable throughout the year. The incidence of falls in 2018/9 (1.90/1000 per persons per day) was significantly lower than in 2008/9 (2.30/1000, p = 0.006). Level ≥ 3b accidents, reflecting serious accidents with complications, were encountered in 12 of 433 accidents in 2008/9 compared with significantly fewer accidents (2 of the same severity among 324 accidents) in 2018/9 (p = 0.030).Our results showed a decrease in in-hospital falls in 2018/9 and that the sufferers were older relative to 10 years earlier. A multidisciplinary team should recommend measures to prevent falls and an environment "resilient" to falls, and encourage patients to be aware of possible falls.
    Language English
    Publishing date 2024-04-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2280747-0
    ISSN 1864-6743 ; 1438-941X ; 1864-6697 ; 0044-3220
    ISSN (online) 1864-6743 ; 1438-941X
    ISSN 1864-6697 ; 0044-3220
    DOI 10.1055/a-2276-0011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A 10-Year Study of the Trend of Accidental Falls in the Elderly in a Japanese Hospital

    Takekawa, Toru / Obuchi, Kei / Watanabe, Shu / Yamada, Naoki / Abo, Masahiro

    Zeitschrift für Orthopädie und Unfallchirurgie

    2024  

    Abstract: Elderly people are prone to falls. We established the Falls Prevention Working Group (FPWG) at our hospital in 2015 to reduce the number of falls during hospitalization. This study compared the trend of in-hospital falls in the elderly in ...

    Abstract Elderly people are prone to falls. We established the Falls Prevention Working Group (FPWG) at our hospital in 2015 to reduce the number of falls during hospitalization. This study compared the trend of in-hospital falls in the elderly in two time periods (2008/9 and 2018/9) and determined the effects of FPWG-implemented measures. Using medical records, we counted the monthly number of falls suffered by patients during hospitalization in April 2008-March 2009 and April 2018-March 2019. We also categorized the falls according to the severity of fall-related complications. A total of 3609 hospital falls were recorded during the 2008–2019 period (2008/9: n = 433, 2018/9: n = 324). Falls were more common in patients aged 70–79 in 2008/9 but were noted in those aged ≥ 80 in 2018/9. The mean number of falls/month (27.3 ± 6.4, range: 12–45) was stable throughout the year. The incidence of falls in 2018/9 (1.90/1000 per persons per day) was significantly lower than in 2008/9 (2.30/1000, p = 0.006). Level ≥ 3b accidents, reflecting serious accidents with complications, were encountered in 12 of 433 accidents in 2008/9 compared with significantly fewer accidents (2 of the same severity among 324 accidents) in 2018/9 (p = 0.030). Our results showed a decrease in in-hospital falls in 2018/9 and that the sufferers were older relative to 10 years earlier. A multidisciplinary team should recommend measures to prevent falls and an environment “resilient” to falls, and encourage patients to be aware of possible falls.
    Keywords accidental falls ; interdisciplinary team ; longevity ; risk management ; prevention and control ; Sturzunfälle ; interdisziplinäres Team ; Langlebigkeit ; Risikomanagement ; Prävention und Kontrolle
    Language English
    Publishing date 2024-04-11
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2280747-0
    ISSN 1864-6743 ; 1438-941X ; 1864-6697 ; 0044-3220
    ISSN (online) 1864-6743 ; 1438-941X
    ISSN 1864-6697 ; 0044-3220
    DOI 10.1055/a-2276-0011
    Database Thieme publisher's database

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  3. Article ; Online: Multimodal treatment, including extracorporeal shock wave therapy, for refractory chronic tension-type headache: a case report.

    Takekawa, Toru / Chino, Toshifumi / Yamada, Naoki / Watanabe, Shu / Abo, Masahiro / Sengoku, Renpei

    Journal of medical case reports

    2023  Volume 17, Issue 1, Page(s) 478

    Abstract: Background: Few reports have described multidisciplinary treatment, including extracorporeal shock wave therapy, for patients with refractory chronic tension-type headache. In this study, we conducted multidisciplinary treatment for a patient with ... ...

    Abstract Background: Few reports have described multidisciplinary treatment, including extracorporeal shock wave therapy, for patients with refractory chronic tension-type headache. In this study, we conducted multidisciplinary treatment for a patient with chronic tension-type headache who suffered from chronic headache refractory to treatment.
    Case presentation: The patient was a 45-year-old Japanese male suffering from 20 years of headache. As his headache had worsened recently, he visited a local clinic. With the diagnosis of suspected tension-type headache, its treatment was unsuccessful and he was referred to our hospital. The neurology department confirmed the tension-type headache and prescribed another medication, but he showed no improvement. Then, the patient was referred to the rehabilitation medicine department for consultation. At the initial visit, we identified multiple myofascial trigger points in his bilateral posterior neck and upper back regions. At the initial visit, he was prescribed 10 mL of 1% lidocaine injected into the muscles in these areas. In addition, he received 2000 extracorporeal shock wave therapy into bilateral trapezius muscles, and was instructed to take oral Kakkonto extract granules, benfotiamine, pyridoxine hydrochloride, and cyanocobalamin. Cervical muscle and shoulder girdle stretches and exercises were also recommended. At follow-up treatment visits, we used extracorporeal shock wave therapy to bilateral trapezius muscles, which led to immediate pain relief. After 11 weeks, he was not taking any medication and his headache was subjectively improved and his medical treatment ended.
    Conclusion: A patient with chronic tension-type headache refractory to regular treatment was successfully treated with a multimodal approach including extracorporeal shock wave therapy in addition to standard treatment. For patients with tension-type headache accompanied by myofascial trigger points, it may be recommended to promptly consider aggressive multimodal treatment that includes extracorporeal shock wave therapy.
    MeSH term(s) Humans ; Male ; Middle Aged ; Combined Modality Therapy ; Extracorporeal Shockwave Therapy ; Headache ; Myofascial Pain Syndromes/complications ; Myofascial Pain Syndromes/diagnosis ; Myofascial Pain Syndromes/therapy ; Tension-Type Headache/therapy ; Tension-Type Headache/diagnosis ; Tension-Type Headache/etiology
    Language English
    Publishing date 2023-10-31
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-04092-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Treatment outcome of local injection of botulinum toxin for claw toe: Differences between cerebral hemorrhage and infarction.

    Takekawa, Toru / Hara, Takatoshi / Yamada, Naoki / Sato, Tomoharu / Hasegawa, Yuki / Takagi, Satoshi / Kobayashi, Kazushige / Kitajima, Tomohide / Abo, Masahiro

    Clinical neurology and neurosurgery

    2023  Volume 226, Page(s) 107620

    Abstract: Background: Some patients with post-stroke claw toe respond well to botulinum toxin (BoNT) treatment while others do not. This study was designed to assess the impact of stroke type (cerebral hemorrhage and cerebral infarction) on the outcome of BoNT ... ...

    Abstract Background: Some patients with post-stroke claw toe respond well to botulinum toxin (BoNT) treatment while others do not. This study was designed to assess the impact of stroke type (cerebral hemorrhage and cerebral infarction) on the outcome of BoNT treatment for claw toe.
    Methods: We retrospectively examined the medical records of patients who received local BoNT (onabotulinumtoxin A) injections into the flexor hallucis longus (FHL) and flexor digitorum longus (FDL) muscles. All patients suffered stroke-related leg paralysis and spasticity.
    Results: The study participants were 58 patients (mean age, 61.4 ± 10.3 years, ± SD) with time since stroke of 6.7 ± 4.4 years. The stroke type was cerebral hemorrhage (n = 38) and cerebral infarction (n = 20). After a total of 124 BoNT administrations with medical records entries on the subjective symptoms, the odds for symptomatic improvement was approximately 5.8 times higher in patients of the infarction group compared with the hemorrhage group (OR = 5.787, 95% CI = 2.369-14.134, p = 0. 000). Fifty-one patients (32 with cerebral hemorrhage, 19 with cerebral infarction) received the first local BoNT injection and had available medical records, analysis of which showed a significantly higher rate of symptomatic improvement in patients of the infarction group than those of the hemorrhage group (p = 0.006). After adjustment by factors known to influence treatment outcome (degree of spasticity and paralysis, BoNT dosage, and extent of FDL muscle control of toe movements), the treatment effect was predominantly higher in patients with cerebral infarction.
    Conclusion: The BoNT treatment response was better for claw toes in cerebral infarction patients than in hemorrhage patients, possibly suggesting that claw toe is associated with more severe spasticity in this group of patients.
    MeSH term(s) Humans ; Middle Aged ; Aged ; Hammer Toe Syndrome/complications ; Retrospective Studies ; Botulinum Toxins, Type A ; Stroke/complications ; Muscle Spasticity ; Paralysis ; Cerebral Hemorrhage/complications ; Treatment Outcome ; Cerebral Infarction/complications ; Infarction/complications ; Neuromuscular Agents
    Chemical Substances Botulinum Toxins, Type A (EC 3.4.24.69) ; Neuromuscular Agents
    Language English
    Publishing date 2023-02-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 193107-6
    ISSN 1872-6968 ; 0303-8467
    ISSN (online) 1872-6968
    ISSN 0303-8467
    DOI 10.1016/j.clineuro.2023.107620
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Claw Toe: Anatomic Guide for Injection of Botulinum Toxin into Foot Muscles.

    Takekawa, Toru / Takagi, Satoshi / Kitajima, Tomohide / Sato, Tomoharu / Kinoshita, Kazuo / Abo, Masahiro

    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

    2021  Volume 49, Issue 1, Page(s) 102–108

    Abstract: Background: Poor response to injection of botulinum toxin (BoNT) into the flexor digitorum longus (FDL) muscle has been reported especially in patients with claw foot deformity. We previously advocated BoNT injection into the flexor hallucis longus (FHL) ...

    Abstract Background: Poor response to injection of botulinum toxin (BoNT) into the flexor digitorum longus (FDL) muscle has been reported especially in patients with claw foot deformity. We previously advocated BoNT injection into the flexor hallucis longus (FHL) muscle in such patients. Here, we determined the functional and anatomical relationships between FHL and FDL.
    Methods: Toe flexion pattern was observed during electrical stimulation of FHL and FDL muscles in 31 post-stroke patients with claw-foot deformity treated with BoNT. The FHL and FDL tendon arrangement was also studied in five limbs of three cadavers.
    Results: Electrical stimulation of the FHL muscle elicited big toe flexion in all 28 cases examined and second toe in 25, but the response was limited to the big toe in 3. FDL muscle stimulation in 29 patients elicited weak big toe flexion in 1 and flexion of four toes (2nd to 5th) in 16 patients. Cadaver studies showed division of the FHL tendon with branches fusing with the FDL tendon in all five limbs examined; none of the tendons was inserted only in the first toe. No branches of the FDL tendon merged with the FHL tendon.
    Conclusion: Our results showed coupling of FHL and FDL tendons in most subjects. Movements of the second and third toes are controlled by both the FDL and FHL muscles. The findings highlight the need for BoNT injection in both the FDL and FHL muscles for the treatment of claw-toe deformity.
    MeSH term(s) Botulinum Toxins/therapeutic use ; Foot ; Hammer Toe Syndrome/drug therapy ; Humans ; Muscle, Skeletal ; Tendons/physiology
    Chemical Substances Botulinum Toxins (EC 3.4.24.69)
    Language English
    Publishing date 2021-03-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2021.52
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Rehabilitation therapy for a severe case of coronavirus disease 2019: a case report.

    Takekawa, Toru / Kashiwabara, Kazumi / Yamada, Naoki / Watanabe, Shu / Hama, Midori / Hashimoto, Gentaro / Abo, Masahiro / Shinfuku, Kyota

    Journal of medical case reports

    2022  Volume 16, Issue 1, Page(s) 339

    Abstract: Background: Patients with severe coronavirus disease 2019 (COVID-19) infection require a long period of time to return to work and society due to significant physical weakness even after recovery. Here we report a patient with a history of nephrectomy ... ...

    Abstract Background: Patients with severe coronavirus disease 2019 (COVID-19) infection require a long period of time to return to work and society due to significant physical weakness even after recovery. Here we report a patient with a history of nephrectomy who developed severe COVID-19 infection associated with muscle weakness but was able to return to society after rehabilitation therapy.
    Case presentation: A Japanese man in his 40s was admitted to the hospital with PCR-based COVID-19 diagnosis. The respiratory condition worsened rapidly and was treated with extracorporeal membrane-assisted ventilation in the intensive case unit. On admission to the Rehabilitation Department on day T + 30 [T: day patient became febrile (38 °C)], he was unable to stand for a long time and used a walker. Rehabilitation therapy was postponed to prevent COVID-19 spread, but the patient was encouraged to exercise during isolation to improve trunk and lower extremity muscle strength. Physical therapy commenced on day T + 49 to improve gait and trunk and lower limb muscle strength. He was able to walk independently and later returned to work following discharge on day T + 53. A computed tomography scan showed an increase in psoas muscle volume from 276 before to 316 cm
    Conclusions: We have described the beneficial effects of rehabilitation therapy in a patient with severe COVID-19 infection. In addition to exercise, we believe that nutrition is even more important in increasing skeletal muscle mass. Rehabilitation therapy is recommended to enhance the return of severely ill COVID-19 patients to routine daily activity.
    MeSH term(s) COVID-19 ; COVID-19 Testing ; Humans ; Male ; Muscle Weakness/etiology ; Physical Therapy Modalities/adverse effects ; Respiration, Artificial
    Language English
    Publishing date 2022-09-02
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-022-03559-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Comparison of the effect and treatment sequence between a 2-week parallel repetitive transcranial magnetic stimulation and rehabilitation and a 2-week rehabilitation-only intervention during a 4-week hospitalization for upper limb paralysis after stroke: An open-label, crossover observational study.

    Yamada, Naoki / Kashiwabara, Kazumi / Takekawa, Toru / Hama, Midori / Niimi, Masachika / Hara, Takatoshi / Furumizo, Satoshi / Tsuboi, Marika

    Journal of central nervous system disease

    2022  Volume 14, Page(s) 11795735211072731

    Abstract: Background: NEURO: Objectives: However, this has not been demonstrated using NEURO: Methods: Thirty-seven patients with upper limb paralysis following stroke were recruited and hospitalized for treatments and randomly divided into two groups. ... ...

    Abstract Background: NEURO
    Objectives: However, this has not been demonstrated using NEURO
    Methods: Thirty-seven patients with upper limb paralysis following stroke were recruited and hospitalized for treatments and randomly divided into two groups. Group A consisted of 16 patients who underwent NEURO
    Results: Group A, who underwent NEURO
    Conclusion: Our findings indicate that rTMS facilitates neuromodulation when combined with OT, which leads to more effective rehabilitation than with OT alone (Trial registration: JMACCT (http://www.jmacct.med.or.jp/); trial ID JMA-IIA00215).
    Language English
    Publishing date 2022-01-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2586873-1
    ISSN 1179-5735
    ISSN 1179-5735
    DOI 10.1177/11795735211072731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of Flexor Digitorum Longus Muscle Anatomical Structure on the Response to Botulinum Toxin Treatment in Patients with Post-Stroke Claw Foot Deformity.

    Takekawa, Toru / Kobayashi, Kazushige / Yamada, Naoki / Takagi, Satoshi / Hara, Takatoshi / Kitajima, Tomohide / Sato, Tomoharu / Sugihara, Hiroshi / Kinoshita, Kazuo / Abo, Masahiro

    Toxins

    2022  Volume 14, Issue 10

    Abstract: 1) Background: The purpose of this retrospective case-control study was to determine the relationship between the control of toe movements by flexor hallucis longus (FHL) and flexor digitorum longus (FDL) muscles and the response to treatment with ... ...

    Abstract (1) Background: The purpose of this retrospective case-control study was to determine the relationship between the control of toe movements by flexor hallucis longus (FHL) and flexor digitorum longus (FDL) muscles and the response to treatment with botulinum toxin (BoNT) in post-stroke patients with claw toe. (2) Methods: Subjects with stroke-related leg paralysis/spasticity and claw toes received multiple injections of BoNT (onabotulinumtoxin A) into the FHL or FDL muscles. We investigated the relationship between the mode of transmission of FHL and FDL muscle tension to each toe (MCT) and treatment outcome using the data of 53 patients who received 124 injections with clinically recorded treatment outcome. We also dissected the potential variables that could determine the treatment outcome. (3) Results: The effectiveness of BoNT treatment was significantly altered by FDL-MCT (OR = 0.400, 95% CI = 0.162-0.987, p = 0.047). Analysis of the response to the first BoNT injection showed an odds ratio of FDL-MCT of approximately 6.0 times (OR = 0.168, 95% CI = 0.033-0.857, p = 0.032). The more tibial the influence of the FDL muscle on each toe, the better the treatment outcome on the claw toe. (4) Conclusions: The anatomic relation between FDL muscle and each toe seems to affect the response to treatment with BoNT in post-stroke patients with claw toes.
    MeSH term(s) Humans ; Hammer Toe Syndrome ; Botulinum Toxins, Type A/therapeutic use ; Case-Control Studies ; Retrospective Studies ; Foot Deformities ; Muscle, Skeletal
    Chemical Substances Botulinum Toxins, Type A (EC 3.4.24.69)
    Language English
    Publishing date 2022-09-25
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins14100666
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Botulinum toxin treatment for difficult-to-treat finger pressure ulcers caused by severe hand flexion: case report.

    Takekawa, Toru / Ikegaya, Mariko / Etoh, Takafumi / Shiio, Yasushi / Sugihara, Hiroshi / Haraikawa, Keiko / Miyamoto, Nozomi / Abo, Masahiro

    Journal of wound care

    2021  Volume 30, Issue 8, Page(s) 653–659

    Abstract: We report the successful treatment of two cases of difficult-to-treat pressure ulcers with botulinum toxin type A (BoNT-A). A 71-year-old male patient with Parkinson's disease presented with severe hand grip deformities of the fingers and a pressure ... ...

    Abstract We report the successful treatment of two cases of difficult-to-treat pressure ulcers with botulinum toxin type A (BoNT-A). A 71-year-old male patient with Parkinson's disease presented with severe hand grip deformities of the fingers and a pressure ulcer (PU) on the right hand. He received 240U of BoNT-A into the upper limb muscles, which improved finger mobility during passive extension and resulted in resolution of the palm PU. No recurrence was noted. A 69-year-old female patient with Lewy body dementia presented with a PU on the palm side of the middle finger apex of the right hand, with exposure of the phalanx bone and dark red oedematous granulation of the tip of the finger. Severe muscle tone was noted. She received 240U of BoNT-A injected into the muscles of the upper extremities. This resulted in the disappearance of the contracture between the middle finger cusp and palm, and prompt healing of the PU. A protective finger orthosis was also used to improve hand finger grip and prevent further PUs. Although BoNT-A injection resulted in only slight improvement in the range of motion, it produced relief of pressure with consequent healing of the PU. Injection of BoNT-A into the affected muscles of the patients in this case report was effective in reducing flexor muscle tone, relief of pressure on the palm skin and healing of hand PUs.
    MeSH term(s) Aged ; Botulinum Toxins, Type A/therapeutic use ; Female ; Hand Strength ; Humans ; Male ; Muscle Spasticity ; Pressure Ulcer/drug therapy ; Range of Motion, Articular ; Treatment Outcome
    Chemical Substances Botulinum Toxins, Type A (EC 3.4.24.69)
    Language English
    Publishing date 2021-04-12
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1353951-6
    ISSN 0969-0700
    ISSN 0969-0700
    DOI 10.12968/jowc.2021.30.8.653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Brain perfusion and upper limb motor function: a pilot study on the correlation between evolution of asymmetry in cerebral blood flow and improvement in Fugl-Meyer Assessment score after rTMS in chronic post-stroke patients.

    Takekawa, Toru / Kakuda, Wataru / Uchiyama, Mayuki / Ikegaya, Masato / Abo, Masahiro

    Journal of neuroradiology = Journal de neuroradiologie

    2013  Volume 41, Issue 3, Page(s) 177–183

    Abstract: Background and purpose: Few studies have explored the refinement of asymmetry in regional cerebral blood flow in relation to behavioral improvement after treatment. The purpose of this retrospective pilot study was to identify cerebral cortical regions ... ...

    Abstract Background and purpose: Few studies have explored the refinement of asymmetry in regional cerebral blood flow in relation to behavioral improvement after treatment. The purpose of this retrospective pilot study was to identify cerebral cortical regions with improved perfusion that correlated with improvement of upper limb motor function after repetitive transcranial magnetic stimulation (rTMS).
    Materials and methods: The study subjects were 33 post-stroke patients with upper limb hemiparesis who underwent rTMS combined with intensive occupational therapy (mean ± SD age: 64.9 ± 11.2 years; time since onset of stroke: 57.3 ± 45.9 months). Fugl-Meyer Assessment (FMA) and the Wolf Motor Function Test (WMFT) were applied before and after treatment to evaluate motor function in the affected upper limb. Regional brain perfusion was measured by single-photon emission computed tomography, and the percentages of asymmetry values (asymmetry index [AI]) for 52 bilateral regions of interest were calculated. The change in AI was calculated as the post-intervention minus pre-intervention values.
    Results: Changes in AI in the superior and middle frontal areas correlated significantly and negatively with changes in FMA score (superior: r = -0.406, P = 0.03, R(2) = 0.251; middle: r = -0.437, P < 0.001, R(2) = 0.306), but not with changes in WMFT log performance time.
    Conclusion: Changes in AI less than zero reflect improved perfusion, suggesting that upper limb motor function improvement in post-stroke patients reflects evolution of brain perfusion in the superior and middle frontal areas.
    MeSH term(s) Blood Flow Velocity ; Brain/diagnostic imaging ; Brain/physiopathology ; Cerebrovascular Circulation ; Chronic Disease ; Humans ; Middle Aged ; Nerve Net/diagnostic imaging ; Nerve Net/physiopathology ; Paresis/diagnostic imaging ; Paresis/physiopathology ; Paresis/prevention & control ; Pilot Projects ; Radionuclide Imaging ; Recovery of Function ; Retrospective Studies ; Severity of Illness Index ; Stroke/diagnostic imaging ; Stroke/physiopathology ; Stroke/therapy ; Transcranial Magnetic Stimulation ; Treatment Outcome ; Upper Extremity/physiopathology
    Language English
    Publishing date 2013-07-22
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 131763-5
    ISSN 1773-0406 ; 0150-9861
    ISSN (online) 1773-0406
    ISSN 0150-9861
    DOI 10.1016/j.neurad.2013.06.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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