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  1. Article ; Online: Pancreatic Interventions: From the Quill to the Sonar.

    Reddy, Duvvur Nageshwar / Talukdar, Rupjyoti

    Gastrointestinal endoscopy clinics of North America

    2023  Volume 33, Issue 4, Page(s) xv–xvi

    Language English
    Publishing date 2023-06-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 1313994-0
    ISSN 1558-1950 ; 1052-5157
    ISSN (online) 1558-1950
    ISSN 1052-5157
    DOI 10.1016/j.giec.2023.05.002
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  2. Article ; Online: Progression of recurrent acute to chronic pancreatitis: More questions than answers!

    Talukdar, Rupjyoti

    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

    2018  Volume 37, Issue 2, Page(s) 77–78

    MeSH term(s) Acute Disease ; Disease Progression ; Humans ; Pancreatitis ; Pancreatitis, Chronic ; Recurrence
    Language English
    Publishing date 2018-03-19
    Publishing country India
    Document type Editorial ; Comment
    ZDB-ID 632595-6
    ISSN 0975-0711 ; 0254-8860
    ISSN (online) 0975-0711
    ISSN 0254-8860
    DOI 10.1007/s12664-018-0839-8
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  3. Article ; Online: Optimizing nutrition in chronic pancreatitis.

    Talukdar, Rupjyoti / Unnisa, Misbah

    Current opinion in gastroenterology

    2022  Volume 38, Issue 5, Page(s) 495–500

    Abstract: Purpose of review: This review aims to discuss recent developments in the nutritional management in chronic pancreatitis.: Recent findings: Nutritional assessment should be comprehensive and include dietary history, anthropometry, and biochemical ... ...

    Abstract Purpose of review: This review aims to discuss recent developments in the nutritional management in chronic pancreatitis.
    Recent findings: Nutritional assessment should be comprehensive and include dietary history, anthropometry, and biochemical nutritional parameters. Micronutrients should be evaluated at least yearly and dual-energy X-ray absorptiometry (DEXA) at every 2-yearly intervals. Studies on pancreatic enzyme replacement therapy (PERT) have primarily evaluated coefficient of fat excretion (CFA), coefficient of nitrogen excretion (CNA), and stool weight. Two RCTs, in which patients were treated with PERT for 7 days in a blinded manner and subsequently extended for 6-12 months in an open-label manner, showed improvement in nutritional parameters. However, two subsequent RCTs failed to show any benefit, and the most recent observational study demonstrated persistence of malnutrition even after PERT. The reason for the latter findings were nonadherence to PERT and poor oral intake of calories. Therefore, it is essential to educate the patients on adherence, counsel on taking high-protein, high-calorie diet, and supplement nutrients in those with inadequate oral intake. Other associated manifestations, such as diabetes and related complications, and anxiety/depression could also contribute to malnutrition directly or indirectly, and should, therefore, be adequately managed.
    Summary: Nutritional assessment should be performed meticulously. Nutritional therapy should not be restricted to only PERT and nutritional supplementation, but should also include dietary counselling and disease related education.
    MeSH term(s) Enzyme Replacement Therapy ; Humans ; Malnutrition/etiology ; Malnutrition/therapy ; Nutritional Status ; Pancreas ; Pancreatitis, Chronic/complications ; Pancreatitis, Chronic/therapy
    Language English
    Publishing date 2022-08-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 632571-3
    ISSN 1531-7056 ; 0267-1379
    ISSN (online) 1531-7056
    ISSN 0267-1379
    DOI 10.1097/MOG.0000000000000866
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  4. Article: Next Generation Sequencing Based Detection of Bacterial Species in Bile After Liver Transplantation. Hope, Hype or Hyperbole?

    Rao, Padaki N / Vishnubhotla, Ravikanth / Talukdar, Rupjyoti

    Journal of clinical and experimental hepatology

    2023  Volume 14, Issue 1, Page(s) 101311

    Language English
    Publishing date 2023-11-30
    Publishing country India
    Document type Editorial
    ISSN 0973-6883
    ISSN 0973-6883
    DOI 10.1016/j.jceh.2023.101311
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  5. Article ; Online: Complications of ERCP.

    Talukdar, Rupjyoti

    Best practice & research. Clinical gastroenterology

    2016  Volume 30, Issue 5, Page(s) 793–805

    Abstract: Even though considered safe, endoscopic retrograde cholangiopancreatography (ERCP) is among the endoscopic procedures associated with the highest rate of complications. Post ERCP pancreatitis (PEP) is the most common complication of ERCP. Several ... ...

    Abstract Even though considered safe, endoscopic retrograde cholangiopancreatography (ERCP) is among the endoscopic procedures associated with the highest rate of complications. Post ERCP pancreatitis (PEP) is the most common complication of ERCP. Several independent risk factors have been associated with PEP. Prophylactic PD stenting has been shown to be highly effective in preventing PEP. More recent studies have suggested that NSAIDs, especially rectal indomethacin, could by itself be effective in preventing PEP. However, head to head RCTs comparing PD stents with NSAIDs would be required to confirm this. Other complications include ERCP induced bleeding, perforation, and cholangitis. Bleeding is related to morphological, procedural, and patient related factors. Early identification and correction of the risk factors are of paramount importance in preventing bleeding. Risk of infection is particularly high during ERCP. It is important to ensure complete drainage of obstructed biliary system in order to reduce the risk of post-ERCP cholangitis.
    MeSH term(s) Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Cholangiopancreatography, Endoscopic Retrograde/adverse effects ; Cholangitis/etiology ; Cholangitis/prevention & control ; Humans ; Infection/etiology ; Pancreatitis/etiology ; Pancreatitis/prevention & control ; Postoperative Hemorrhage/etiology ; Risk Factors ; Stents
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal
    Language English
    Publishing date 2016-10
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2048181-0
    ISSN 1532-1916 ; 1521-6918
    ISSN (online) 1532-1916
    ISSN 1521-6918
    DOI 10.1016/j.bpg.2016.10.007
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  6. Article ; Online: Are all post-ESWL pancreatitis events clinically significant?

    Singh, Aniruddha Pratap Haripal / Talukdar, Rupjyoti / Ramchandani, Mohan / Reddy, Duvvur Nageshwar

    The lancet. Gastroenterology & hepatology

    2022  Volume 7, Issue 7, Page(s) 593

    MeSH term(s) Calculi/therapy ; Humans ; Lithotripsy ; Pancreatitis/etiology
    Language English
    Publishing date 2022-06-15
    Publishing country Netherlands
    Document type Letter ; Comment
    ISSN 2468-1253
    ISSN (online) 2468-1253
    DOI 10.1016/S2468-1253(22)00119-4
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  7. Article ; Online: Long-term Outcome of Peroral Endoscopic Myotomy in Esophageal Motility Disorders: A Systematic Review and Meta-analysis.

    Nabi, Zaheer / Mandavdhare, Harshal / Akbar, Wahid / Talukdar, Rupjyoti / Reddy, Duvvur Nageshwar

    Journal of clinical gastroenterology

    2023  Volume 57, Issue 3, Page(s) 227–238

    Abstract: Background and aim: Peroral endoscopic myotomy (POEM) is an established treatment for achalasia. In this systematic review and meta-analysis, we aimed to analyze the mid and long-term outcomes of POEM in esophageal motility disorders.: Methods: ... ...

    Abstract Background and aim: Peroral endoscopic myotomy (POEM) is an established treatment for achalasia. In this systematic review and meta-analysis, we aimed to analyze the mid and long-term outcomes of POEM in esophageal motility disorders.
    Methods: Literature search was performed in databases including PubMed, Embase, Cochrane databases, and Google scholar from January 2010 to May 2021. The primary objective of the study was the clinical success (Eckardt score ≤3 or <4) at mid-term (30 to 60 mo) and long-term (>60 mo) follow-up after POEM. Secondary objectives included post-POEM gastroesophageal reflux (GER) as evaluated by symptoms, increased esophageal acid exposure, and reflux esophagitis.
    Results: Seventeen studies with 3591 patients were included in the review. Subtypes of motility disorders were type I (27%), type II (54.5%), type III (10.7%), distal esophageal spasm/Jackhammer esophagus (2%), and esophagogastric junction outflow obstruction (17.5%). Pooled mean follow-up duration was 48.9 months (95% CI, 40.02-57.75). Pooled rate of clinical success at mid-term follow-up was 87% (95% CI, 81-91; I2 , 86%) and long-term was 84% (95% CI, 76-89; I2 , 47%). In nonachalasia motility disorders (esophagogastric junction outflow obstruction, distal esophageal spasm, and Jackhammer esophagus), pooled rate of clinical success was 77% (95% CI, 65-85; I2 , 0%). GER as estimated by symptoms was 23% (95% CI, 19-27; I2 , 74%), erosive esophagitis was 27% (95% CI, 18-38%; I2 , 91%), and increased esophageal acid exposure was 41% (95% CI, 30-52; I2 , 88%).
    Conclusion: POEM is a durable treatment option in cases with achalasia. One-fourth of patients suffer from erosive GER in the long-term and success rates are lower in nonachalasia esophageal motility disorders.
    MeSH term(s) Humans ; Esophageal Achalasia/surgery ; Esophageal Achalasia/complications ; Esophageal Spasm, Diffuse/complications ; Treatment Outcome ; Esophageal Motility Disorders/surgery ; Esophageal Motility Disorders/complications ; Gastroesophageal Reflux/complications ; Esophagitis, Peptic/complications ; Myotomy ; Natural Orifice Endoscopic Surgery ; Esophageal Sphincter, Lower ; Esophagoscopy
    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 448460-5
    ISSN 1539-2031 ; 0192-0790
    ISSN (online) 1539-2031
    ISSN 0192-0790
    DOI 10.1097/MCG.0000000000001776
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    Zs.A 1523: Show issues Location:
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  8. Article: Outcomes of Endoscopic Drainage in Children with Pancreatic Fluid Collections: A Systematic Review and Meta-Analysis.

    Nabi, Zaheer / Talukdar, Rupjyoti / Lakhtakia, Sundeep / Reddy, D Nageshwar

    Pediatric gastroenterology, hepatology & nutrition

    2022  Volume 25, Issue 3, Page(s) 251–262

    Abstract: Purpose: Endoscopic drainage is an established treatment modality for adult patients with pancreatic fluid collections (PFCs). Available data regarding the efficacy and safety of endoscopic drainage in pediatric patients are limited. In this systematic ... ...

    Abstract Purpose: Endoscopic drainage is an established treatment modality for adult patients with pancreatic fluid collections (PFCs). Available data regarding the efficacy and safety of endoscopic drainage in pediatric patients are limited. In this systematic review and meta-analysis, we aimed to analyze the outcomes of endoscopic drainage in children with PFCs.
    Methods: A literature search was performed in Embase, PubMed, and Google Scholar for studies on the outcomes of endoscopic drainage with or without endoscopic ultrasonography (EUS) guidance in pediatric patients with PFCs from inception to May 2021. The study's primary objective was clinical success, defined as resolution of PFCs. The secondary outcomes included technical success, adverse events, and recurrence rates.
    Results: Fourteen studies (187 children, 70.3% male) were included in this review. The subtypes of fluid collection included pseudocysts (60.3%) and walled-off necrosis (39.7%). The pooled technical success rates in studies where drainage of PFCs were performed with and without EUS guidance were 95.3% (95% confidence interval [CI], 89.6-98%;
    Conclusion: Endoscopic drainage is safe and effective in children with PFCs. However, future studies are required to compare endoscopic and EUS-guided drainage of PFCs in children.
    Language English
    Publishing date 2022-05-09
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3032413-0
    ISSN 2234-8840 ; 2234-8646
    ISSN (online) 2234-8840
    ISSN 2234-8646
    DOI 10.5223/pghn.2022.25.3.251
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  9. Article ; Online: Ethambutol optic neuropathy in the extended anti-tubercular therapy regime: A systematic review.

    Sabhapandit, Swapnali / Gella, Vishwanath / Shireesha, Anumula / Thankachan, Ledo / Ismail, Mohamad / Rao, Raghava / Talukdar, Rupjyoti

    Indian journal of ophthalmology

    2023  Volume 71, Issue 3, Page(s) 729–735

    Abstract: The extended use of ethambutol beyond 2 months for treating tuberculosis has increased risk of optic neuropathy. We performed a systematic review of studies evaluating optic neuropathy in extended ethambutol use since 2010 and compared the outcome with a ...

    Abstract The extended use of ethambutol beyond 2 months for treating tuberculosis has increased risk of optic neuropathy. We performed a systematic review of studies evaluating optic neuropathy in extended ethambutol use since 2010 and compared the outcome with a similar systematic review (1965-2010) by Ezer et al. Literature search was conducted in PubMed, Medline, EMBASE, and Cochrane databases. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Main outcome measures were visual acuity, color vision, visual field defects, optical coherence tomography (OCT), and visual evoked potential (VEP). The JBI Critical Appraisal Checklists were used for quality assessment. Twelve studies were selected (out of 639 studies) for analysis of ethambutol optic neuropathy. Visual acuity improvement after stopping ethambutol was statistically significant. Similar improvement was not noted for other outcome measures. On comparing the results of this review with those by Ezer et al., significant improvement was noted in visual acuity, color vision, and visual field defects. Moreover, more patients reported increased optic nerve toxicity, color vision defects, and visual field defects in the present review. Hence, we conclude that the extended use of ethambutol beyond 2 months results in significant optic nerve toxicity. Further randomized controlled trials with different populations are needed to understand the magnitude of this issue.
    MeSH term(s) Humans ; Ethambutol ; Evoked Potentials, Visual ; Optic Nerve Diseases ; Optic Nerve ; Checklist ; Rare Diseases
    Chemical Substances Ethambutol (8G167061QZ)
    Language English
    Publishing date 2023-03-06
    Publishing country India
    Document type Systematic Review ; Journal Article ; Review ; Comment
    ZDB-ID 187392-1
    ISSN 1998-3689 ; 0301-4738
    ISSN (online) 1998-3689
    ISSN 0301-4738
    DOI 10.4103/ijo.IJO_1920_22
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  10. Article ; Online: Comments on "Endoscopic sleeve gastroplasty, laparoscopic sleeve gastrectomy, and laparoscopic greater curve plication: do they differ at 2 years?"

    Katakwar, Abishek / Lakhtakia, Sundeep / Talukdar, Rupjyoti

    Endoscopy

    2021  Volume 53, Issue 3, Page(s) 339

    MeSH term(s) Gastrectomy/adverse effects ; Gastroplasty/adverse effects ; Humans ; Laparoscopy
    Language English
    Publishing date 2021-02-25
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1308-1998
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