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  1. AU="Tam, Ka Cheung"
  2. AU="Richardson, Susan E"
  3. AU="Generoso, Erika Marie G"
  4. AU="Moustafa, Ahmed M"
  5. AU="da Cruz, Luciana D"
  6. AU="Ratnayake, Jithendra"
  7. AU="Halesh, L H"
  8. AU=Babajanyan S G
  9. AU="Haruhara, Kotaro"
  10. AU="Wang, Che-Wei"
  11. AU="Eisenberg, Marcia"
  12. AU="Ufnalska, Sylwia"
  13. AU="Leroux, Dominique"
  14. AU="Gallagher, Timothy J"
  15. AU=Baggish Aaron
  16. AU="Bush, Ashley I"
  17. AU="Carr, Kenneth D."
  18. AU="Spiro, Stephen"
  19. AU="Roberts, William Clifford"
  20. AU="Park, Hyungjong"
  21. AU="Das, Debasish"
  22. AU="Sanz-Magro, Adrián"
  23. AU="Fan, Shanhui"
  24. AU="Ellonen, Pekka"
  25. AU="Lambert, T"
  26. AU="Vivekanandan, Rajesh"

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  1. Artikel: Exacerbated VEGF up-regulation accompanies diabetes-aggravated hemorrhage in mice after experimental cerebral ischemia and delayed reperfusion.

    Lai, Angela Ka Wai / Ng, Tsz Chung / Hung, Victor Ka Lok / Tam, Ka Cheung / Cheung, Chi Wai / Chung, Sookja Kim / Lo, Amy Cheuk Yin

    Neural regeneration research

    2021  Band 17, Heft 7, Seite(n) 1566–1575

    Abstract: Reperfusion therapy is the preferred treatment for ischemic stroke, but is hindered by its short treatment window, especially in patients with diabetes whose reperfusion after prolonged ischemia is often accompanied by exacerbated hemorrhage. The ... ...

    Abstract Reperfusion therapy is the preferred treatment for ischemic stroke, but is hindered by its short treatment window, especially in patients with diabetes whose reperfusion after prolonged ischemia is often accompanied by exacerbated hemorrhage. The mechanisms underlying exacerbated hemorrhage are not fully understood. This study aimed to identify this mechanism by inducing prolonged 2-hour transient intraluminal middle cerebral artery occlusion in diabetic Ins2
    Sprache Englisch
    Erscheinungsdatum 2021-12-16
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.330612
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Neuropeptide α-Melanocyte-Stimulating Hormone Promotes Neurological Recovery and Repairs Cerebral Ischemia/Reperfusion Injury in Type 1 Diabetes.

    Goit, Rajesh Kumar / Ng, Tsz Chung / Tam, Ka Cheung / Tsang, Jessica K W / Taylor, Andrew W / Lo, Amy C Y

    Neurochemical research

    2021  Band 47, Heft 2, Seite(n) 394–408

    Abstract: Persons with type 1 diabetes have an increased risk of stroke compared with the general population. α-Melanocyte-stimulating hormone (α-MSH) is a neuropeptide that has protective effects against ischemia/reperfusion (I/R) induced organ damages. In this ... ...

    Abstract Persons with type 1 diabetes have an increased risk of stroke compared with the general population. α-Melanocyte-stimulating hormone (α-MSH) is a neuropeptide that has protective effects against ischemia/reperfusion (I/R) induced organ damages. In this study, we aimed to investigate the neuroprotective role of this peptide on I/R induced brain damage after experimental stroke associated with hyperglycemia using C57BL/6J Ins2
    Mesh-Begriff(e) Animals ; Brain Ischemia/drug therapy ; Diabetes Mellitus, Type 1/drug therapy ; Humans ; Mice ; Mice, Inbred C57BL ; Reperfusion Injury/metabolism ; alpha-MSH/pharmacology ; alpha-MSH/therapeutic use
    Chemische Substanzen alpha-MSH (581-05-5)
    Sprache Englisch
    Erscheinungsdatum 2021-09-29
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 199335-5
    ISSN 1573-6903 ; 0364-3190
    ISSN (online) 1573-6903
    ISSN 0364-3190
    DOI 10.1007/s11064-021-03453-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Long-term lutein administration attenuates retinal inflammation and functional deficits in early diabetic retinopathy using the Ins2

    Wang, Wei / Tam, Ka Cheung / Ng, Tsz Chung / Goit, Rajesh Kumar / Chan, Kate Lok San / Lo, Amy Cheuk Yin

    BMJ open diabetes research & care

    2020  Band 8, Heft 1

    Abstract: Introduction: Lutein is a carotenoid whose protective effects in the retina have been reported in various studies. The effect of lutein has not been reported in the retina of the Ins2: Research design and methods: Heterozygous male Ins2: Results: ... ...

    Abstract Introduction: Lutein is a carotenoid whose protective effects in the retina have been reported in various studies. The effect of lutein has not been reported in the retina of the Ins2
    Research design and methods: Heterozygous male Ins2
    Results: Increased microglial reactivity was detected in the Ins2
    Conclusions: We showed beneficial effects of long-term lutein administration in the Ins2
    Mesh-Begriff(e) Animals ; Diabetes Mellitus, Experimental ; Diabetic Retinopathy/drug therapy ; Humans ; Inflammation ; Lutein/pharmacology ; Lutein/therapeutic use ; Male ; Mice ; Mice, Inbred C57BL ; Retina ; Vascular Endothelial Growth Factor A
    Chemische Substanzen Vascular Endothelial Growth Factor A ; Lutein (X72A60C9MT)
    Sprache Englisch
    Erscheinungsdatum 2020-07-11
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2732918-5
    ISSN 2052-4897 ; 2052-4897
    ISSN (online) 2052-4897
    ISSN 2052-4897
    DOI 10.1136/bmjdrc-2020-001519
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Evidence for the interaction of peroxiredoxin-4 with the store-operated calcium channel activator STIM1 in liver cells.

    Tam, Ka Cheung / Ali, Eunus / Hua, Jin / Chataway, Tim / Barritt, Greg J

    Cell calcium

    2018  Band 74, Seite(n) 14–28

    Abstract: ... ...

    Abstract Ca
    Mesh-Begriff(e) Animals ; Endoplasmic Reticulum, Rough/chemistry ; Endoplasmic Reticulum, Rough/metabolism ; Hepatocytes/chemistry ; Hepatocytes/metabolism ; Male ; Microsomes, Liver/chemistry ; Microsomes, Liver/metabolism ; ORAI1 Protein/analysis ; ORAI1 Protein/metabolism ; Peroxiredoxins/analysis ; Peroxiredoxins/metabolism ; Protein Binding/physiology ; Rats ; Rats, Wistar ; Stromal Interaction Molecule 1/analysis ; Stromal Interaction Molecule 1/metabolism
    Chemische Substanzen ORAI1 Protein ; Orai1 protein, rat ; Stim1 protein, rat ; Stromal Interaction Molecule 1 ; Peroxiredoxins (EC 1.11.1.15) ; Prdx4 protein, rat (EC 1.11.1.15)
    Sprache Englisch
    Erscheinungsdatum 2018-05-15
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 757687-0
    ISSN 1532-1991 ; 0143-4160
    ISSN (online) 1532-1991
    ISSN 0143-4160
    DOI 10.1016/j.ceca.2018.05.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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