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  1. Article: Recommencement of atezolizumab with associated pulmonary sarcoid-like reaction.

    Tam, Khai / Wallace, Michael / Mulrennan, Siobhain

    Respirology case reports

    2024  Volume 12, Issue 5, Page(s) e01363

    Abstract: An 81 year old male with Child-Pugh A cirrhosis and metastatic hepatocellular carcinoma (HCC) treated with 3-weekly atezolizumab and bevacizumab developed a pulmonary sarcoid-like reaction (SLR) after 5 months. Atezolizumab, an immune checkpoint ... ...

    Abstract An 81 year old male with Child-Pugh A cirrhosis and metastatic hepatocellular carcinoma (HCC) treated with 3-weekly atezolizumab and bevacizumab developed a pulmonary sarcoid-like reaction (SLR) after 5 months. Atezolizumab, an immune checkpoint inhibitor, was identified as the likely culprit. He was treated with prednisolone, resulting in improvement, and was successfully rechallenged with both atezolizumab and bevacizumab.
    Language English
    Publishing date 2024-04-26
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2750180-2
    ISSN 2051-3380
    ISSN 2051-3380
    DOI 10.1002/rcr2.1363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Medical students' perceptions of the importance of exercise and their perceived competence in prescribing exercise to older people.

    Jadczak, Agathe Daria / Tam, Khai Loon / Yu, Solomon / Visvanathan, Renuka

    Australasian journal on ageing

    2017  Volume 36, Issue 3, Page(s) E7–E13

    Abstract: Objective: To determine the effects of a 4.5-week geriatric medicine course on fifth year medical students' perception of the importance of and their competence in prescribing exercise to older people.: Methods: The modified Exercise and Physical ... ...

    Abstract Objective: To determine the effects of a 4.5-week geriatric medicine course on fifth year medical students' perception of the importance of and their competence in prescribing exercise to older people.
    Methods: The modified Exercise and Physical Activity Competence Questionnaire was administered to 81 students before and after the course. Scores ranged from 0 to 6. One open-ended question about perceived barriers to exercise prescription was asked.
    Results: Students' perceptions of the importance of designing an exercise prescription (P = 0.038), determining the training heart rate (P = 0.021), determining the body mass index (P > 0.001), referring an older person to an exercise program (P > 0.001) and identifying age-related limitations (P = 0.029) improved significantly after the course. Students' self-perceived competence improved significantly across all items (P > 0.001). Barriers to exercise prescription included lack of: knowledge (57%), patient compliance (39%) and time (33%).
    Conclusion: A geriatric medicine course contributes to improved senior medical students' perceptions of importance of and their competence in prescribing exercise to older people.
    Language English
    Publishing date 2017-09
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1457406-8
    ISSN 1741-6612 ; 0726-4240 ; 1440-6381
    ISSN (online) 1741-6612
    ISSN 0726-4240 ; 1440-6381
    DOI 10.1111/ajag.12412
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  3. Article ; Online: Fifth-year medical students' perceptions of the importance of frailty and competence in assessing, diagnosing and managing frailty before and after a geriatric medicine course.

    Arakawa Martins, Beatriz / Jadczak, Agathe Daria / Dollard, Joanne / Barrie, Helen / Mahajan, Neha / Tam, Khai Loon / Visvanathan, Renuka

    Australasian journal on ageing

    2020  Volume 39, Issue 3, Page(s) e472–e477

    Abstract: Objective: To assess the changes in fifth-year medical students' perceptions of the importance of frailty and competence in assessing, diagnosing and managing frailty after a 4.5-week geriatric medicine course.: Methods: Students' perceived ... ...

    Abstract Objective: To assess the changes in fifth-year medical students' perceptions of the importance of frailty and competence in assessing, diagnosing and managing frailty after a 4.5-week geriatric medicine course.
    Methods: Students' perceived importance and competence was assessed before and after the course using a 26-item Likert scale questionnaire with scores ranging from 1 to 6.
    Results: Students' perceptions of the importance of defining frailty (P = .01), explaining what frailty is (P = .03), advising on nutritional needs (P = .001) and exercise (P = .001) and prescribing an exercise program (P < .001) significantly improved after the course. Medical students' perceived competence in assessing, diagnosing and managing frailty was low to moderate precourse and increased significantly postcourse (2.3 [1.2] 4.9 [2.9], mean [IQR], P < .001) across all items.
    Conclusion: An appropriate curriculum focusing on geriatric health conditions such as frailty can improve senior medical students' perceived importance and competence in assessing, diagnosing and managing frailty.
    MeSH term(s) Aged ; Clinical Competence ; Curriculum ; Education, Medical, Undergraduate ; Frailty/diagnosis ; Frailty/therapy ; Geriatrics/education ; Humans ; Perception ; Students, Medical ; Surveys and Questionnaires
    Language English
    Publishing date 2020-03-02
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1457406-8
    ISSN 1741-6612 ; 0726-4240 ; 1440-6381
    ISSN (online) 1741-6612
    ISSN 0726-4240 ; 1440-6381
    DOI 10.1111/ajag.12788
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  4. Article ; Online: Evaluation of the introduction of the OSCE to the fifth-year Geriatric Medicine Teaching Programme.

    Vanlint, Andrew / Tam, Khai Loon / Yu, Solomon / Visvanathan, Renuka

    Australasian journal on ageing

    2016  Volume 35, Issue 4, Page(s) 285–288

    Abstract: Aim: An Observed Structured Clinical Examination (OSCE) was integrated into the assessment for senior medical students undertaking a 4.5-week geriatric medicine teaching block at one campus. The feasibility and acceptability of an OSCE were examined.: ...

    Abstract Aim: An Observed Structured Clinical Examination (OSCE) was integrated into the assessment for senior medical students undertaking a 4.5-week geriatric medicine teaching block at one campus. The feasibility and acceptability of an OSCE were examined.
    Methods: Students completed eight questions regarding the OSCE using a 6-point Likert scale and two additional questions, using free text, highlighting the strengths and potential areas for improvement. Changes were made every 6 months over a two-year period in response to student evaluation.
    Results: Improvements included adjusting the format to conform with end-of-year examinations and introducing simulated patients. Following these improvements, students perceived improved structure and sequence to the assessments, improved opportunity for demonstration of skills and knowledge and that the assessment was fair.
    Conclusion: This preliminary research provides evidence that it is feasible to introduce OSCE as a form of assessment into a geriatric medicine teaching programme and student evaluation can be used to inform improvements.
    MeSH term(s) Curriculum ; Education, Medical, Undergraduate/methods ; Educational Measurement/methods ; Educational Status ; Feasibility Studies ; Feedback, Psychological ; Geriatrics/education ; Hospitals, Teaching ; Humans ; Learning ; Program Evaluation ; Students, Medical/psychology ; Surveys and Questionnaires ; Teaching
    Language English
    Publishing date 2016-12
    Publishing country Australia
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 1457406-8
    ISSN 1741-6612 ; 0726-4240 ; 1440-6381
    ISSN (online) 1741-6612
    ISSN 0726-4240 ; 1440-6381
    DOI 10.1111/ajag.12352
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  5. Article ; Online: Bisphosphonate-associated atypical subtrochanteric femur fractures in the older patient.

    Gopal, Gopinath K / Tam, Khai L / Krishnan, Shibu P / Maddern, Ian L

    The New Zealand medical journal

    2014  Volume 127, Issue 1389, Page(s) 81–85

    Abstract: Bisphosphonates, drug of choice in the treatment of osteoporosis, have been associated with unusual skeletal side effects such as osteonecrosis of jaw and atypical femur fractures in recent years. We report two older patients with bisphosphonate- ... ...

    Abstract Bisphosphonates, drug of choice in the treatment of osteoporosis, have been associated with unusual skeletal side effects such as osteonecrosis of jaw and atypical femur fractures in recent years. We report two older patients with bisphosphonate-associated atypical femur fracture from a South Australian tertiary care hospital and a brief discussion of potential diagnostic complexities in this patient population.
    MeSH term(s) Aged ; Alendronate/adverse effects ; Bone Density Conservation Agents/adverse effects ; Diphosphonates/adverse effects ; Etidronic Acid/adverse effects ; Etidronic Acid/analogs & derivatives ; Female ; Femoral Fractures/complications ; Femoral Fractures/diagnostic imaging ; Femoral Fractures/etiology ; Humans ; Osteoporosis, Postmenopausal/complications ; Osteoporosis, Postmenopausal/drug therapy ; Radiography ; Risedronate Sodium
    Chemical Substances Bone Density Conservation Agents ; Diphosphonates ; Etidronic Acid (M2F465ROXU) ; Risedronate Sodium (OFG5EXG60L) ; Alendronate (X1J18R4W8P)
    Language English
    Publishing date 2014-02-14
    Publishing country New Zealand
    Document type Case Reports ; Journal Article
    ZDB-ID 390590-1
    ISSN 1175-8716 ; 0028-8446 ; 0110-7704
    ISSN (online) 1175-8716
    ISSN 0028-8446 ; 0110-7704
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  6. Article ; Online: Geriatric medicine course to senior undergraduate medical students improves attitude and self-perceived competency scores.

    Tam, Khai Loon / Chandran, Khobe / Yu, Solomon / Nair, Shailaja / Visvanathan, Renuka

    Australasian journal on ageing

    2014  Volume 33, Issue 4, Page(s) E6–11

    Abstract: Aims: The aims were to evaluate the effect of a 4.5-week geriatric medicine course on 5th-year medical students' attitudes and self-perceived competency scores. Student performance in the summative multiple choice questions examination in 2011 was ... ...

    Abstract Aims: The aims were to evaluate the effect of a 4.5-week geriatric medicine course on 5th-year medical students' attitudes and self-perceived competency scores. Student performance in the summative multiple choice questions examination in 2011 was compared with results from 2008.
    Methods: Pre- and post-course attitudes (University of California, Los Angeles Attitudes Survey) and self-perceived competency surveys were administered to 65 5th-year medical students following a 4.5-week geriatric medicine course at one South Australian teaching hospital as part of course evaluation and improvement.
    Results: Significant improvements in students' attitude (mean pre- and post-attitude score (± standard deviation): 3.34 (1.66) vs 3.66 (1.06); P < 0.001) and self-perceived competency (mean pre and post-competency scores: 2.89 (0.84) and 4.03 (0.56); P < 0.001) were observed. The 2011 multiple choice question results were much better than in 2008 (91.5 (3.6) vs 75.2 (7.9); P < 0.001).
    Conclusions: A geriatric medicine course for senior medical students allows for improvement in attitudes and self-perceived competency scores.
    MeSH term(s) Attitude of Health Personnel ; Clinical Competence ; Curriculum ; Education, Medical, Undergraduate/methods ; Educational Measurement ; Geriatrics/education ; Health Knowledge, Attitudes, Practice ; Hospitals, Teaching ; Humans ; Program Evaluation ; Self Concept ; South Australia ; Students, Medical/psychology ; Surveys and Questionnaires ; Teaching
    Language English
    Publishing date 2014-12
    Publishing country Australia
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 1457406-8
    ISSN 1741-6612 ; 0726-4240 ; 1440-6381
    ISSN (online) 1741-6612
    ISSN 0726-4240 ; 1440-6381
    DOI 10.1111/ajag.12060
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  7. Article: Relationships of ratings of appetite to food intake in healthy older men and women.

    Parker, Barbara A / Ludher, Anyssa K / Loon, Tam Khai / Horowitz, Michael / Chapman, Ian M

    Appetite

    2004  Volume 43, Issue 3, Page(s) 227–233

    Abstract: The aim of this study was to determine how rated appetite relates to the amount eaten in a meal in healthy older people. On two study days, 32 healthy older men (n = 16) and women (n = 16) aged 65-85 years, recruited by advertisement, consumed a ... ...

    Abstract The aim of this study was to determine how rated appetite relates to the amount eaten in a meal in healthy older people. On two study days, 32 healthy older men (n = 16) and women (n = 16) aged 65-85 years, recruited by advertisement, consumed a standardised breakfast and 4 h later were offered lunch from which they could eat freely. Foods eaten at lunch were weighed and energy intake calculated from nutrient composition data. Appetite was assessed at baseline and at 30-min intervals between meals by line ratings of hunger, fullness, nausea and how much could be eaten. The optimum time for correlations both among appetite ratings and between appetite and lunch intake was just before the lunch. Mean coefficients of repeatability (21-38 mm) and correlation coefficients (0.67-0.71) at that point in time were similar to those reported previously in young adults. Thus, in older and well as young adults, the size of a meal is most closely related to rated appetite just before the meal.
    MeSH term(s) Aged ; Aged, 80 and over ; Appetite/physiology ; Eating/physiology ; Eating/psychology ; Energy Intake/physiology ; Female ; Humans ; Hunger/physiology ; Male ; Nausea ; Reproducibility of Results ; Satiation/physiology ; Time Factors
    Language English
    Publishing date 2004-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 764440-1
    ISSN 0195-6663
    ISSN 0195-6663
    DOI 10.1016/j.appet.2004.05.004
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