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  1. Article ; Online: HLA alleles associated with susceptibility and severity of the COVID-19 in Vietnamese.

    Hai, Nguyen Thi Thanh / Nhung, Vu Phuong / Tam, Nguyen Thi Thanh / Ngoc, Tran Thi Bich / Thuong, Ma Thi Huyen / Dai, Ha Van / Duong, Nguyen Thuy / Hai, Nong Van / Ton, Nguyen Dang / Thach, Pham Ngoc / Ha, Nguyen Hai

    Human immunology

    2024  , Page(s) 110796

    Abstract: The diversity of clinical manifestations in COVID-19 has been observed not only among individuals but also among various populations in globally. HLA molecules play a central role in physiology, protective immunity, and deleterious, disease-related ... ...

    Abstract The diversity of clinical manifestations in COVID-19 has been observed not only among individuals but also among various populations in globally. HLA molecules play a central role in physiology, protective immunity, and deleterious, disease-related autoimmune reactivity or overreaction. This study exploited the association between HLA frequencies and SARS-CoV-2 susceptibility and disease severity among the Vietnamese cohort (159 patients and 52 controls). A significant difference in frequency of both HLA class I and II in mild, moderate, and severe/fatal COVID-19 patients and negative exposure individuals - the controls were observed. Regarding SARS-CoV-2 sensitivity, HLA-A*03:01, 30:01, HLA-DQA1*01:02, DRB1*15:01, and DRB5*02:02 presented higher frequency in the control group compared with infected patients but DRB1 09:01 frequency was higher in infected patients. Regarding COVID-19 severity, HLA-F*01:01, 01:03 and DPA1*01:03 and 02:01, DPB1*04:01, DQA1*01:02, and DQB1*05:02 alleles were detected with higher frequency in severe patients but DOB*01:01, DRB1*05:01 and 09:01 had a significantly higher frequency in the mild group than remaining groups. Surprisingly, HLA-DQA1*01:02 and DRB1*09:01 alleles were identified with both inversely potential roles in protective function and severe risk. The obtained data herein will contribute to explore on the role of host genetic background in the pathology of COVID-19 disease.
    Language English
    Publishing date 2024-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 801524-7
    ISSN 1879-1166 ; 0198-8859
    ISSN (online) 1879-1166
    ISSN 0198-8859
    DOI 10.1016/j.humimm.2024.110796
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Should Scrotal Color Doppler Ultrasound Be Routinely Indicated in Fertility Evaluation of Non-Azoospermic Men?

    Le, Minh Tam / Nguyen, Dac Nguyen / Tam Nguyen, Thi Thanh / Nguyen, Vu Quoc Huy / Pham, Chi Kong / Le, Dinh Duong / Cao, Ngoc Thanh

    Current urology

    2020  Volume 14, Issue 4, Page(s) 211–218

    Abstract: Objective: Scrotal ultrasound is not a routine investigation in the clinical approach to male infertility analysis. This study aims to identify the role of testicular Doppler ultrasound in male infertility assessment and its relation to semen parameters ...

    Abstract Objective: Scrotal ultrasound is not a routine investigation in the clinical approach to male infertility analysis. This study aims to identify the role of testicular Doppler ultrasound in male infertility assessment and its relation to semen parameters in non-azoospermic men.
    Methods: Cross-sectional descriptive analysis of 558 men from infertile couples were examined at the Hue Center for Reproductive Endocrinology and Infertility, Hue University Hospital from June 2016 to May 2018. Some cohort characteristics, semen analysis and testicular Doppler ultrasound were analyzed. Men with acute systemic diseases, acute urinary tract infection, hepatic dysfunction, malignant diseases, retrograde ejaculation, cryptorchidism or azoospermia were excluded.
    Results: The mean volumes of the right and left testicles were 8.87 and 8.77 ml, respectively. The total volume of the 2 sides was 17.63 ± 4.34 ml (95% confidence interval 17.27-18.00 ml). The mean right resistive index (RI) was 0.61 ± 0.23, and the mean left RI was 0.59 ± 0.01. The rate of normal semen quality was 23.2% in group with varicocele and 30.6% in group with non-varicocele. The ultrasound results from the normal semen group were much different from those of the abnormal semen group regarding testicular volume: mean right testis volume: 9.67 ± 1.88 vs. 8.75 ± 2.34 ml, p = 0.0096; mean left testis volume: 9.54 ± 1.78 vs. 8.51 ± 2.44 ml, p = 0.0047; mean total volume of 2 sides: 19.21 ± 3.60 vs. 17.26 ± 4.59 ml, p = 0.005 (varicocele group); mean right testis volume: 9.21 ± 2.21 vs. 8.63 ± 2.21 ml, p = 0.029 (non-varicocele group). The other indexes of color Doppler ultrasound (peak systolic velocity, end diastolic velocity, RI) were not found to correlate with semen quality.
    Conclusions: Testicular volume which has a close relation to the semen parameters could be used as a clinical prediction factor for the quality of semen.
    Language English
    Publishing date 2020-12-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2253664-4
    ISSN 1661-7657 ; 1661-7649
    ISSN (online) 1661-7657
    ISSN 1661-7649
    DOI 10.1159/000499236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Effectiveness of different biochar in aqueous zinc removal: Correlation with physicochemical characteristics

    Van Hien, Nguyen / Valsami-Jones, Eugenia / Vinh, Nguyen Cong / Phu, Tong Thi / Tam, Nguyen Thi Thanh / Lynch, Iseult

    Bioresource technology reports. 2020 Sept., v. 11

    2020  

    Abstract: Bochar from typical Vietnamese biomass residues (acacia wood chip, rice husk, bamboo) were assessed for application in remediation of metal-contaminated water. The biochar physical (e.g., surface area, morphology) and chemical (e.g. surface functional ... ...

    Abstract Bochar from typical Vietnamese biomass residues (acacia wood chip, rice husk, bamboo) were assessed for application in remediation of metal-contaminated water. The biochar physical (e.g., surface area, morphology) and chemical (e.g. surface functional groups, proximate and elemental analysis) characteristics were correlated with their effectiveness in removing zinc (Zn²⁺). The impact of biochar dose, contact time, and initial adsorbate concentration were investigated to determine the adsorption capacity of the biochar for Zn²⁺. All three effectively remove Zn²⁺ from aqueous solution, with bamboo biochar especially efficient (removal of 96–98% Zn²⁺ from 40 to 80 mg/L). Maximum adsorptions were 7.62, 4.02, and 3.82 mg Zn²⁺/L for bamboo, wood, and rice husk biochar, respectively. The Freundlich model fit the adsorption of Zn²⁺, and a pseudo-second order model described the adsorption kinetics. Adsorption was governed by chelation with biochar organic groups (-COOH, -OH⁻) and precipitation onto inorganic groups (CO₃²⁻, PO₄²⁻), not ion exchange.
    Keywords Acacia ; adsorption ; aqueous solutions ; bamboos ; biochar ; biomass ; chelation ; ion exchange ; models ; remediation ; rice hulls ; sorption isotherms ; surface area ; technology ; wood ; wood chips ; zinc
    Language English
    Dates of publication 2020-09
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-AP-2-clean
    ISSN 2589-014X
    DOI 10.1016/j.biteb.2020.100466
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: The mCME Project

    Christopher J Gill / Bao Le Ngoc / Nafisa Halim / Ha Nguyen Viet / Anna Larson Williams / Tan Nguyen Van / Marion McNabb / Lien Tran Thi Ngoc / Ariel Falconer / Hai An Phan Ha / Julia Rohr / Hai Hoang / James Michiel / Tam Nguyen Thi Thanh / Liat Bird / Hoang Pham Vu / Mahlet Yeshitla / Nhu Ha Van / Lora Sabin

    PLoS ONE, Vol 11, Iss 11, p e

    A Randomized Controlled Trial of an SMS-Based Continuing Medical Education Intervention for Improving Medical Knowledge among Vietnamese Community Based Physicians' Assistants.

    2016  Volume 0166293

    Abstract: Community health workers (CHWs) provide critical services to underserved populations in low and middle-income countries, but maintaining CHW's clinical knowledge through formal continuing medical education (CME) activities is challenging and rarely ... ...

    Abstract Community health workers (CHWs) provide critical services to underserved populations in low and middle-income countries, but maintaining CHW's clinical knowledge through formal continuing medical education (CME) activities is challenging and rarely occurs. We tested whether a Short Message Service (SMS)-based mobile CME (mCME) intervention could improve medical knowledge among a cadre of Vietnamese CHWs (Community Based Physician's Assistants-CBPAs) who are the leading providers of primary medical care for rural underserved populations.The mCME Project was a three arm randomized controlled trial. Group 1 served as controls while Groups 2 and 3 experienced two models of the mCME intervention. Group 2 (passive model) participants received a daily SMS bullet point, and were required to reply to the text to acknowledge receipt; Group 3 (interactive model) participants received an SMS in multiple choice question format addressing the same thematic area as Group 2, entering an answer (A, B, C or D) in their response. The server provided feedback immediately informing the participant whether the answer was correct. Effectiveness was based on standardized examination scores measured at baseline and endline (six months later). Secondary outcomes included job satisfaction and self-efficacy.638 CBPAs were enrolled, randomized, and tested at baseline, with 592 returning at endline (93.7%). Baseline scores were similar across all three groups. Over the next six months, participation of Groups 2 and 3 remained high; they responded to >75% of messages. Group 3 participants answered 43% of the daily SMS questions correctly, but their performance did not improve over time. At endline, the CBPAs reported high satisfaction with the mCME intervention, and deemed the SMS messages highly relevant. However, endline exam scores did not increase over baseline, and did not differ between the three groups. Job satisfaction and self-efficacy scores also did not improve. Average times spent on self-study per week did not increase, and ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 796
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Maternal body mass index and gestational weight gain and their association with perinatal outcomes in Viet Nam.

    Ota, Erika / Haruna, Megumi / Suzuki, Motoi / Anh, Dang Duc / Tho, Le Huu / Tam, Nguyen Thi Thanh / Thiem, Vu Dinh / Anh, Nguyen Thi Hien / Isozaki, Mitsuhiro / Shibuya, Kenji / Ariyoshi, Koya / Murashima, Sachiyo / Moriuchi, Hiroyuki / Yanai, Hideki

    Bulletin of the World Health Organization

    2010  Volume 89, Issue 2, Page(s) 127–136

    Abstract: Objective: To examine the association between gestational weight gain and maternal body mass index (BMI) among Vietnamese women and the risk of delivering an infant too small or too large for gestational age.: Methods: A prospective health-facility- ... ...

    Abstract Objective: To examine the association between gestational weight gain and maternal body mass index (BMI) among Vietnamese women and the risk of delivering an infant too small or too large for gestational age.
    Methods: A prospective health-facility-based study of 2989 pregnant Vietnamese women was conducted in the city of Nha Trang in 2007-2008. Cubic logistic regression was used to investigate the association of interest. Infants were classified into weight-for-gestational-age categories according to weight centiles for the Asian population. Gestational age was based on the date of last menstrual period and adjusted by the results of first-trimester ultrasound.
    Findings: BMI was low (< 18.5), normal (18.5-22.9) and high (≥ 23.0) in 26.1%, 65.4% and 8.5% of the women, respectively. In each of these BMI categories, the percentage of women who delivered infants too small for gestational age was 18.1, 10.0 and 9.4, respectively, and the mean gestational weight gain was 12.5 kg (standard deviation, SD: ± 3.6), 12.2 kg (SD: ± 3.8) and 11.5 kg (SD: ± 4.7), respectively. Among women with low BMI, the risk of delivering an infant too small for gestational age ranged from approximately 40% if the gestational weight gain was < 5 kg to 20% if it was 5-10 kg.
    Conclusion: Having a low BMI, commonly found in Viet Nam, puts women at risk of delivering an infant too small for gestational age, especially when total maternal gestational weight gain is < 10 kg.
    MeSH term(s) Adult ; Birth Weight ; Body Mass Index ; Female ; Gestational Age ; Humans ; Logistic Models ; Maternal Welfare ; Pregnancy ; Pregnancy Outcome ; Prenatal Care ; Program Development ; Prospective Studies ; Risk Factors ; Vietnam ; Weight Gain
    Language English
    Publishing date 2010-11-10
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80213-x
    ISSN 1564-0604 ; 0042-9686 ; 0366-4996 ; 0510-8659
    ISSN (online) 1564-0604
    ISSN 0042-9686 ; 0366-4996 ; 0510-8659
    DOI 10.2471/BLT.10.077982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Journal ; Article ; Online: Maternal body mass index and gestational weight gain and their association with perinatal outcomes in Viet Nam

    Ota, Erika / Haruna, Megumi / Suzuki, Motoi / Anh, Dang Duc / Tho, Le Huu / Tam, Nguyen Thi Thanh / Thiem, Vu Dinh / Anh, Nguyen Thi Hien / Isozaki, Mitsuhiro / Shibuya, Kenji / Ariyoshi, Koya / Murashima, Sachiyo / Moriuchi, Hiroyuki / Yanai, Hideki

    2011  

    Abstract: ... 127 ... ...

    Abstract 127

    136
    Keywords Research
    Publisher World Health Organization
    Document type Journal ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Aetiologies of central nervous system infection in Viet Nam

    Nghia Ho Dang Trung / Tu Le Thi Phuong / Marcel Wolbers / Hoang Nguyen Van Minh / Vinh Nguyen Thanh / Minh Pham Van / Nga Tran Vu Thieu / Tan Le Van / Diep To Song / Phuong Le Thi / Thao Nguyen Thi Phuong / Cong Bui Van / Vu Tang / Tuan Hoang Ngoc Anh / Dong Nguyen / Tien Phan Trung / Lien Nguyen Thi Nam / Hao Tran Kiem / Tam Nguyen Thi Thanh /
    James Campbell / Maxine Caws / Jeremy Day / Menno D de Jong / Chau Nguyen Van Vinh / H Rogier Van Doorn / Hien Tran Tinh / Jeremy Farrar / Constance Schultsz / VIZIONS CNS Infection Network

    PLoS ONE, Vol 7, Iss 5, p e

    a prospective provincial hospital-based descriptive surveillance study.

    2012  Volume 37825

    Abstract: Infectious diseases of the central nervous system (CNS) remain common and life-threatening, especially in developing countries. Knowledge of the aetiological agents responsible for these infections is essential to guide empiric therapy and develop a ... ...

    Abstract Infectious diseases of the central nervous system (CNS) remain common and life-threatening, especially in developing countries. Knowledge of the aetiological agents responsible for these infections is essential to guide empiric therapy and develop a rational public health policy. To date most data has come from patients admitted to tertiary referral hospitals in Asia and there is limited aetiological data at the provincial hospital level where most patients are seen.We conducted a prospective Provincial Hospital-based descriptive surveillance study in adults and children at thirteen hospitals in central and southern Viet Nam between August 2007-April 2010. The pathogens of CNS infection were confirmed in CSF and blood samples by using classical microbiology, molecular diagnostics and serology.We recruited 1241 patients with clinically suspected infection of the CNS. An aetiological agent was identified in 640/1241 (52%) of the patients. The most common pathogens were Streptococcus suis serotype 2 in patients older than 14 years of age (147/617, 24%) and Japanese encephalitis virus in patients less than 14 years old (142/624, 23%). Mycobacterium tuberculosis was confirmed in 34/617 (6%) adult patients and 11/624 (2%) paediatric patients. The acute case fatality rate (CFR) during hospital admission was 73/617 (12%) in adults and to 42/624 (7%) in children.Zoonotic bacterial and viral pathogens are the most common causes of CNS infection in adults and children in Viet Nam.
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2012-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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