LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article ; Online: Spirulina platensis (Cyanophyta) İle Hazırlanan Tablet ve Kapsüllerin in vitro Kalite Kontrol Çalışmaları.

    H. Yeşim Karasulu / Meltem Conk Dalay / Evren Şanal / Tamer Güneri

    Su Ürünleri Dergisi, Vol 18, Iss

    2015  Volume 1

    Keywords - ; Aquaculture. Fisheries. Angling ; SH1-691 ; Ecology ; QH540-549.5
    Language English
    Publishing date 2015-12-01T00:00:00Z
    Publisher Ege University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Comparative bone uptake study of alendronate sodium from vaginal suppositories prepared with polyethylene glycol and massa estarinum bases

    Derya İlem-Özdemir / Kamil Köseoğlu / Makbule Aşıkoğlu / Hayal Özkılıç / Tamer Güneri

    Marmara Pharmaceutical Journal, Vol 17, Iss 3, Pp 165-

    2013  Volume 169

    Abstract: The aim of this study was to compare the bone uptake of alendronate sodium (ALD) from vaginal suppositories prepared with massa estarinum AB (ME) and polyethylene glycol 1500 (PEG) bases. For this purpose, ALD was radiolabeled with 99mTecnetium ... ...

    Abstract The aim of this study was to compare the bone uptake of alendronate sodium (ALD) from vaginal suppositories prepared with massa estarinum AB (ME) and polyethylene glycol 1500 (PEG) bases. For this purpose, ALD was radiolabeled with 99mTecnetium Pertechnetate (99mTc) by direct method. Radiochemical purity and stability of 99mTc-ALD was performed with chromatographic studies. 99mTc-ALD containing suppositories were prepared with ME and PEG bases. Physical properties of suppositories were evaluated. The physicochemical diffusion study was carried out to compare the release of ALD from different suppository bases. The bone uptake of 99mTc-ALD was observed by gamma scintigraphy studies. 99mTc-ALD containing suppositories were administrated to rabbits via vaginal route. The scintigraphic images were obtained with a gamma camera at different time intervals up to 240 minutes. According to our studies, radiochemical purity of 99mTc-ALD was observed more than 95% up to 6 hours. At 240 minutes of physicochemical diffusion studies, released ALD has 0.620 ± 0.091 mm and 10.465 ± 0.651 mm diameter zone from ME and PEG base suppositories respectively. According to the gamma scintigraphy studies, although no bone uptake observed after ME suppositories application, rabbit’s bones were clearly visible after PEG suppositories applied. The results of physicochemical diffusion and gamma scintigraphy studies were found compatible in each other
    Keywords Alendronate sodium ; bone uptake ; vaginal suppository ; massa estarinum ; polyethylene glyco ; Pharmacy and materia medica ; RS1-441 ; Medicine ; R ; DOAJ:Pharmacy and materia medica ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 500
    Publishing date 2013-09-01T00:00:00Z
    Publisher Marmara University Faculty of Pharmacy
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Quality by design approach for tablet formulations containing spray coated ramipril by using artificial intelligence techniques

    Buket AKSU / Marcel DE MATAS / Erdal CEVHER / Yıldız ÖZSOY / Tamer GÜNERİ / Peter YORK

    International Journal of Drug Delivery, Vol 4, Iss 1, Pp 59-

    2012  Volume 69

    Abstract: Different software programs based on mathematical models have been developed to aid the product development process. Recent developments in mathematics and computer science have resulted in new programs based on artificial neural networks (ANN) ... ...

    Abstract Different software programs based on mathematical models have been developed to aid the product development process. Recent developments in mathematics and computer science have resulted in new programs based on artificial neural networks (ANN) techniques. These programs have been used to develop and formulate pharmaceutical products. In this study, intelligent software was used to predict the relationship between the materials that were used in tablet formulation and the tablet specifications and to determine highly detailed information about the interactions between the formulation parameters and the specifications. The input data were generated from historical data and the results obtained from analyzing tablets produced by different formulations. The relative significance of inputs on various outputs such as assay, dissolution in 30 min and crushing strengths, was investigated using the artificial neural networks (ANNs), neurofuzzy logic and genetic programming (FormRules, INForm ANN and GEP). This study indicated that ANN and GEP can be used effectively for optimizing formulations and that GEP can be evaluated statistically because of the openness of its equations. Additionally, FormRules was very helpful for teasing out the relationships between the inputs (formulation variables) and the outputs.
    Keywords Quality by Design ; Artificial Neural Networks ; FormRules ; ramipril ; spray drying ; tablet ; Pharmacy and materia medica ; RS1-441 ; Medicine ; R
    Subject code 006
    Language English
    Publishing date 2012-09-01T00:00:00Z
    Publisher Advanced Research Journals
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Spirulina platensis (Cyanophyta) İle Hazırlanan Tablet ve Kapsüllerin in vitro Kalite Kontrol Çalışmaları.

    Evren Şanal / H. Yeşim Karasulu / Meltem Conk Dalay / Tamer Güneri

    Su Ürünleri Dergisi, Vol 18, Iss

    2001  Volume 1

    Keywords - ; Aquaculture. Fisheries. Angling ; SH1-691 ; Ecology ; QH540-549.5
    Language English
    Publishing date 2001-03-01T00:00:00Z
    Publisher Ege University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: In vitro Quality Control Studies of Tablets and Capsules Prepared with Spirulina platensis (Cyanophyta).

    H. Yeşim Karasulu / Meltem Conk Dalay / Evren Şanal / Tamer Güneri

    Su Ürünleri Dergisi, Vol 18, Iss

    2001  Volume 1

    Keywords Aquaculture. Fisheries. Angling ; SH1-691 ; Ecology ; QH540-549.5
    Language English
    Publishing date 2001-03-01T00:00:00Z
    Publisher Ege University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Spirulina platensis (Cyanophyta) İle Hazırlanan Tablet ve Kapsüllerin in vitro Kalite Kontrol Çalışmaları.

    H. Yeşim Karasulu / Meltem Conk Dalay / Evren Şanal / Tamer Güneri

    Su Ürünleri Dergisi, Vol 18, Iss

    2001  Volume 1

    Keywords - ; Aquaculture. Fisheries. Angling ; SH1-691 ; Ecology ; QH540-549.5
    Language English
    Publishing date 2001-03-01T00:00:00Z
    Publisher Ege University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top