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  1. Article ; Online: Metastatic lung cancer, an interesting stroke mimic.

    Torrance, Hew David Thomas / Tan, Kai Lee / Jackson, Ava

    BMJ case reports

    2014  Volume 2014

    Abstract: An elderly man presented to the emergency department with symptoms of a left-sided weakness. A CT of the brain scan showed an abnormality, and he was diagnosed with a stroke and admitted to the stroke unit. The stroke consultant reviewed him the next ... ...

    Abstract An elderly man presented to the emergency department with symptoms of a left-sided weakness. A CT of the brain scan showed an abnormality, and he was diagnosed with a stroke and admitted to the stroke unit. The stroke consultant reviewed him the next morning; a detailed history was acquired and imaging reviewed. As a result of the history of neurological symptoms, a diagnosis of malignancy was suspected and an MRI of the brain was ordered. This did not show a stroke but suggested a mass lesion. A CT of the chest, abdomen and pelvis was ordered to rule out a primary cause. Unfortunately, this showed widespread metastatic carcinoma with a left upper lobe primary (T4 N3 M1b). This was confirmed on histology. The patient died soon after the diagnosis.
    MeSH term(s) Adenocarcinoma/complications ; Adenocarcinoma/diagnosis ; Adenocarcinoma/secondary ; Aged ; Brain/diagnostic imaging ; Brain/pathology ; Brain Neoplasms/complications ; Brain Neoplasms/diagnosis ; Brain Neoplasms/secondary ; Diagnosis, Differential ; Fatal Outcome ; Humans ; Lung Neoplasms/complications ; Lung Neoplasms/pathology ; Magnetic Resonance Imaging ; Male ; Stroke/diagnosis ; Stroke/etiology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2014-01-21
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2013-201699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A very sudden onset of tracheomalacia with an unknown cause.

    Javaid, Mahvesh Rana / Tan, Kai Lee / Ahmed, Yasser Noeman

    BMJ case reports

    2013  Volume 2013

    MeSH term(s) Aged ; Humans ; Male ; Tomography, X-Ray Computed ; Tracheomalacia/diagnosis ; Tracheomalacia/diagnostic imaging ; Tracheomalacia/etiology
    Language English
    Publishing date 2013-05-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2013-009375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.

    Charles Santhanaraju Vairappan / Takahiro Ishii / Tan Kai Lee / Minoru Suzuki / Zhan Zhaoqi

    Marine Drugs, Vol 8, Iss 6, Pp 1743-

    2010  Volume 1749

    Abstract: In our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10- ... ...

    Abstract In our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10-acetoxyangasiol (1), and four other known metabolites, aplysidiol (2), cupalaurenol (3), 1-methyl-2,3,5-tribromoindole (4), and chamigrane epoxide (5), were isolated and identified. Isolated metabolites exhibited potent antibacterial activities against clinical bacteria, Staphylococcus aureus, Staphylococcus sp., Streptococcus pyogenes, Salmonella sp. and Vibrio cholerae.
    Keywords Laurencia sp ; halogenated metabolites ; antibacterial activity ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2010-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Role of secondary metabolites as defense chemicals against ice-ice disease bacteria in biofouler at carrageenophyte farms

    Vairappan, Charles S / Anangdan, Sangeetha P / Tan, Kai Lee / Matsunaga, Shigeki

    Journal of applied phycology. 2010 June, v. 22, no. 3

    2010  

    Abstract: Carrageenophyte farming is an expanding economical activity in North Borneo Island, Malaysia. During routine monitoring of “ice-ice” disease and epiphyte outbreak at commercial farms, it was apparent that culture lines were heavily (60-80%) infested with ...

    Abstract Carrageenophyte farming is an expanding economical activity in North Borneo Island, Malaysia. During routine monitoring of “ice-ice” disease and epiphyte outbreak at commercial farms, it was apparent that culture lines were heavily (60-80%) infested with biofoulers, particularly Acanthophora spp. and Laurencia majuscula. However, only L. majuscula showed dominance and flourished even during “ice-ice” disease outbreak. Presence of chemical defense against seaweed pathogens was investigated in two populations of L. majuscula collected from three major carrageenophyte farms in two districts; (A) Lohok Butun, Selakan Island, and Bum-Bum Island, in Semporna district, and (B) Telutuh, Carrington Reef, and Balambangan Island, in Kudat district. The first population contained elatol (1), and iso-obtusol (2), and, second population contained (Z)-10,15-dibromo-9-hydroxy-chamigra-1,3(15),7(14)-triene (3) and (E)-10-15-dibromo-9-hydroxy-chamigra-1,3(15),7(14)-triene (4), as their antibacterial metabolites. All four metabolites showed highly selective inhibition against “ice-ice” disease bacteria compared to human pathogens at 30 µg disk⁻¹. In addition, seasonal variation of these compounds at two representative farms (Selakan Island [P-1] and Balambangan Island [P-2]) revealed a 120-170% increase in concentration during “ice-ice” disease outbreak. Microscopy of fresh specimens showed the presence of corps en cerise, which is the synthesis and storage site of halogenated metabolites at superficial cortical cells, branch tips, and trichoblasts. This suggests the importance of these metabolites as defense chemicals against “ice-ice” disease bacteria in L. majuscula that grows on seaweed culture lines.
    Keywords Acanthophora ; Laurencia ; bacteria ; commercial farms ; epiphytes ; farming systems ; humans ; macroalgae ; microscopy ; monitoring ; pathogens ; seasonal variation ; seaweed culture ; secondary metabolites ; Borneo ; Malaysia
    Language English
    Dates of publication 2010-06
    Size p. 305-311.
    Publisher Springer Netherlands
    Publishing place Dordrecht
    Document type Article
    ZDB-ID 1002324-0
    ISSN 1573-5176 ; 0921-8971
    ISSN (online) 1573-5176
    ISSN 0921-8971
    DOI 10.1007/s10811-009-9460-7
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 89/703: Show issues

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  5. Article ; Online: Perforated pyloroduodenal peptic ulcer and sonography.

    Kuzmich, Siarhei / Harvey, Chris J / Fascia, Daniel T M / Kuzmich, Tatsiana / Neriman, Deena / Basit, Rizwan / Tan, Kai Lee

    AJR. American journal of roentgenology

    2012  Volume 199, Issue 5, Page(s) W587–94

    Abstract: Objective: The purpose of this article is to illustrate the spectrum of sonographic findings in perforated pyloroduodenal peptic ulcer and discuss the potential role of sonography in the diagnosis.: Conclusion: Although sonography is not the first- ... ...

    Abstract Objective: The purpose of this article is to illustrate the spectrum of sonographic findings in perforated pyloroduodenal peptic ulcer and discuss the potential role of sonography in the diagnosis.
    Conclusion: Although sonography is not the first-line investigation of choice in suspected perforated peptic ulcer, understanding of the characteristic appearances seen during general abdominal sonography may aid the reader in the diagnosis of this important and sometimes overlooked cause of nonspecific abdominal pain. This may shorten time to the diagnosis and ultimate surgical management.
    MeSH term(s) Adult ; Aged ; Diagnosis, Differential ; Duodenal Ulcer/diagnostic imaging ; Female ; Humans ; Male ; Middle Aged ; Peptic Ulcer Perforation/diagnostic imaging ; Pneumoperitoneum/diagnostic imaging ; Stomach Ulcer/diagnostic imaging ; Ultrasonography
    Language English
    Publishing date 2012-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.11.8292
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.57: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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