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  1. Article: The use of corn distiller’s dried grains with solubles as a protein source in practical diets for Pacific white leg shrimp Litopenaeus vannamei

    Novriadi, Romi / Suwendi, Erwin / Tan, Ronnie

    Aquaculture reports. 2022 Aug., v. 25

    2022  

    Abstract: A two-stage growth trial using identical diets was conducted to examine the viability of partially replacing soybean meal (SBM) with corn distiller’s dried grain with solubles (DDGS) simulating the commercial growth cycle of shrimp from 1 g to 19 g body ... ...

    Abstract A two-stage growth trial using identical diets was conducted to examine the viability of partially replacing soybean meal (SBM) with corn distiller’s dried grain with solubles (DDGS) simulating the commercial growth cycle of shrimp from 1 g to 19 g body weight. In both trials, the reference diet was formulated using 25 % SBM, 8 % fish meal (FM) and 20 % poultry by-product meal (PBPM). Test diets were formulated by replacing SBM with 5 %, 10 % and 15 % of DDGS, respectively. All diets contain approximately 36 % crude protein and 7 % crude lipid. In trial 1, fifteen shrimp with average initial weight of 1.04 ± 0.04 g were stocked into 98 l aquaria tank (equivalent to 150 shrimp m⁻²) in a completely randomized design with ten replicates per treatment and fed with the experimental diets for 52 days. In trial 2, shrimp (5.2 ± 0.2 g) were stocked randomly into 200 L clear tanks at a density of 50 shrimp per tank (equivalent to 250 shrimp m⁻²) with eight replicates per treatment and fed for 84 days. The results showed growth performance of shrimp in both studies was not affected as the dietary SBM was partially replaced with DDGS. There were no significant differences observed in terms of crude protein, fat content, dry matter and ash content of the shrimp in both studies. The results from this study demonstrated that corn DDGS could be used up to 15 % in commercial feed formulations without causing any adverse effect on growth, feed conversion, nutrient utilization efficiency and whole body composition. Since the price per unit protein of corn DDGS is much cheaper than SBM, the use of corn DDGS could offer the development of sustainable and economically sound practical diets for Pacific white leg shrimp L. vannamei.
    Keywords Litopenaeus vannamei ; adverse effects ; aquaculture ; ash content ; body composition ; body weight ; corn ; crude protein ; feed conversion ; fish meal ; growth performance ; lipid content ; lipids ; poultry meal ; prices ; protein sources ; shrimp ; soybean meal ; viability
    Language English
    Dates of publication 2022-08
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 2835391-2
    ISSN 2352-5134
    ISSN 2352-5134
    DOI 10.1016/j.aqrep.2022.101209
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Dupilumab in type 2 airway inflammation-a step forward in targeted therapy for COPD.

    Tan, Ronnie Voon Shiong / Aung, Hnin Wint Wint / Flynn, Cara / Greening, Neil J / Brightling, Christopher E

    The Journal of allergy and clinical immunology

    2023  Volume 153, Issue 2, Page(s) 404–406

    MeSH term(s) Humans ; Inflammation/drug therapy ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Antibodies, Monoclonal, Humanized/therapeutic use
    Chemical Substances dupilumab (420K487FSG) ; Antibodies, Monoclonal, Humanized
    Language English
    Publishing date 2023-11-07
    Publishing country United States
    Document type Editorial
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2023.10.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: White precipitate in a dialysis circuit.

    Chia, Chelsea / Lim, Desiree Xin Ying / Ng, Shi Yang / Tan, Ronnie Voon Shiong

    Annals of the Academy of Medicine, Singapore

    2022  Volume 51, Issue 8, Page(s) 517–519

    MeSH term(s) Humans ; Renal Dialysis
    Language English
    Publishing date 2022-09-13
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    DOI 10.47102/annals-acadmedsg.202270
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Promises and challenges of biologics for severe asthma.

    Tan, Ronnie / Liew, Mei Fong / Lim, Hui Fang / Leung, Bernard P / Wong, W S Fred

    Biochemical pharmacology

    2020  Volume 179, Page(s) 114012

    Abstract: Patients with severe asthma that remain uncontrolled incur significant medical burden and healthcare costs. Severe asthma is a heterogeneous airway disorder with complex pathophysiological mechanisms which can be broadly divided into type 2 (T2)-high and ...

    Abstract Patients with severe asthma that remain uncontrolled incur significant medical burden and healthcare costs. Severe asthma is a heterogeneous airway disorder with complex pathophysiological mechanisms which can be broadly divided into type 2 (T2)-high and T2-low inflammatory pathways. Recent advances in asthma therapeutics with the advent of biologics have heralded an era of promising targeted therapy in this group of patients. The current available biologics, including anti-IgE mAb, anti-IL-5/IL-5R mAb and anti-IL-4Rα mAb, mainly target patients with an asthma endotype characterised by T2-high inflammation. While they have delivered positive outcomes in terms of reduction in exacerbations, improving lung function and quality of life, as well as reducing the dependence on oral corticosteroids, they have not functioned as the "panacea" as a significant proportion of patients do not respond completely to these targeted therapies. In addition, there is a lack of markers that can predict treatment response and clinicians are guided only by subjective asthma symptom scores. Suboptimal treatment response is common for individual patients. There has also been a dearth of effective targeted therapy for patients with T2-low asthma and treatment options remain limited for these patients. There is a pipeline of newer biologics targeting cytokines that operate at the interface between innate and adaptive immunity (e.g. IL-17A, thymic stromal lymphopoietin (TSLP), IL-25, IL-33, IL-32 and IL-36γ) with potential of modifying and reducing the severity of asthma. This commentary provides an overview of treatment with the current biologics and highlights the limitations, challenges and unmet needs in clinical management. We also summarise up-and-coming potential targets and therapeutic biologics for severe asthma.
    MeSH term(s) Anti-Asthmatic Agents/administration & dosage ; Anti-Asthmatic Agents/therapeutic use ; Antibodies, Monoclonal, Humanized/pharmacology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Asthma/drug therapy ; Asthma/metabolism ; Asthma/physiopathology ; Biological Products/administration & dosage ; Biological Products/therapeutic use ; Cytokines/metabolism ; Humans ; Immunoglobulin E/blood ; Interleukin-17/metabolism ; Interleukin-5/antagonists & inhibitors ; Interleukin-5/blood ; Molecular Targeted Therapy/methods ; Omalizumab/pharmacology ; Omalizumab/therapeutic use
    Chemical Substances Anti-Asthmatic Agents ; Antibodies, Monoclonal, Humanized ; Biological Products ; Cytokines ; IL5 protein, human ; Interleukin-17 ; Interleukin-5 ; Omalizumab (2P471X1Z11) ; Immunoglobulin E (37341-29-0) ; dupilumab (420K487FSG) ; mepolizumab (90Z2UF0E52)
    Language English
    Publishing date 2020-05-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 208787-x
    ISSN 1873-2968 ; 0006-2952
    ISSN (online) 1873-2968
    ISSN 0006-2952
    DOI 10.1016/j.bcp.2020.114012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Medicare beneficiaries' use of computers and internet: 1998-2005.

    Tan, Ronnie L

    Health care financing review

    2006  Volume 28, Issue 2, Page(s) 45–51

    MeSH term(s) Aged ; Aged, 80 and over ; Community Participation ; Computers/utilization ; Female ; Humans ; Insurance, Pharmaceutical Services ; Internet/utilization ; Male ; Medicare ; United States
    Language English
    Publishing date 2006
    Publishing country United States
    Document type Journal Article
    ZDB-ID 761645-4
    ISSN 1554-9887 ; 0195-8631
    ISSN (online) 1554-9887
    ISSN 0195-8631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Conference proceedings: Proceedings of the Aquaculture Feed Processing and Nutrition Workshop, Thailand and Indonesia, September 19-25, 1991

    Akiyama, Dean Mikio / Tan, Ronnie K. H

    1991  

    Institution American Soybean Association
    Event/congress Aquaculture Feed Processing and Nutrition Workshop (1991, ThailandandIndonesia)
    Author's details edited by Dean M. Akiyama and Ronnie K.H. Tan
    Keywords Aquaculture ; Fishes/Feeding and feeds/Congresses. ; Shrimps/Feeding and feeds/Congresses.
    Language English
    Size 241 p. :, ill. (some col.) ;, 28 cm.
    Publisher American Soybean Association
    Publishing place Singapore
    Document type Book ; Conference proceedings
    Database NAL-Catalogue (AGRICOLA)

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