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  1. Article ; Online: Increase Attention to Computed Tomography Findings of Emphysema without Airflow Limitation: Small Airway Disease Is Already There.

    Tanabe, Naoya

    American journal of respiratory and critical care medicine

    2024  Volume 209, Issue 6, Page(s) 619–621

    MeSH term(s) Humans ; Cross-Sectional Studies ; Pulmonary Disease, Chronic Obstructive ; Pulmonary Emphysema/diagnostic imaging ; Asthma ; Emphysema ; Tomography
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202312-2245ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Narrative review of current COPD status in Japan.

    Tanabe, Naoya / Sato, Susumu

    Journal of thoracic disease

    2021  Volume 13, Issue 6, Page(s) 3878–3887

    Abstract: Chronic obstructive pulmonary disease (COPD) causes morbidity and mortality worldwide. Due to the improvement in environmental sanitation and medical care, the general life span has increased in the past decades in Japan. However, many older patients ... ...

    Abstract Chronic obstructive pulmonary disease (COPD) causes morbidity and mortality worldwide. Due to the improvement in environmental sanitation and medical care, the general life span has increased in the past decades in Japan. However, many older patients with COPD develop a wide range of comorbidities, and the impairments in the activities of daily living result in frailty and increase social and economic burdens. Population-based studies have shown that the prevalence of COPD is approximately 10% among subjects aged ≥40 years, but more than 80% of COPD patients are underdiagnosed. The Ministry of Health, Labour, and Welfare in Japan proposed the National Health Promotion in the 21st century, termed Health Japan 21 (the second term), in 2013 to prevent the onset and progression of noncommunicable diseases (NCDs), including COPD. The government, medical society, and community have been attempting to increase the recognition of COPD and promote smoking cessation. Additionally, Japanese cohorts have revealed distinct clinical features in Japanese patients with COPD, including lower rates of patient-reported exacerbations, less frequent coexisting cardiovascular disease and metabolic syndrome, and lower use of inhaled corticosteroids in Japan compared to the Western countries. Moreover, the poor adherence to inhaled medications is found in approximately 20% of subjects, and rehabilitation is performed in 26% of hospitalized patients with COPD. Therefore, more efforts should be made to improve adherence and access to pulmonary rehabilitation. Overall, Japanese COPD patients share common clinical and social features with COPD patients in other countries. Further international corroboration may help establish better comprehensive management of the disease.
    Language English
    Publishing date 2021-06-29
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd-20-2263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Recent advances in airway imaging using micro-computed tomography and computed tomography for chronic obstructive pulmonary disease.

    Tanabe, Naoya / Hirai, Toyohiro

    The Korean journal of internal medicine

    2021  Volume 36, Issue 6, Page(s) 1294–1304

    Abstract: Chronic obstructive pulmonary disease (COPD) is a complex lung disease characterized by a combination of airway disease and emphysema. Emphysema is classified as centrilobular emphysema (CLE), paraseptal emphysema (PSE), or panlobular emphysema (PLE), ... ...

    Abstract Chronic obstructive pulmonary disease (COPD) is a complex lung disease characterized by a combination of airway disease and emphysema. Emphysema is classified as centrilobular emphysema (CLE), paraseptal emphysema (PSE), or panlobular emphysema (PLE), and airway disease extends from the respiratory, terminal, and preterminal bronchioles to the central segmental airways. Although clinical computed tomography (CT) cannot be used to visualize the small airways, micro-CT has shown that terminal bronchiole disease is more severe in CLE than in PSE and PLE, and micro-CT findings suggest that the loss and luminal narrowing of terminal bronchioles is an early pathological change in CLE. Furthermore, the introduction of ultra-high-resolution CT has enabled direct evaluation of the proximal small (1 to 2-mm diameter) airways, and new CT analytical methods have enabled estimation of small airway disease and prediction of future COPD onset and lung function decline in smokers with and without COPD. This review discusses the literature on micro-CT and the technical advancements in clinical CT analysis for COPD. Hopefully, novel micro-CT findings will improve our understanding of the distinct pathogeneses of the emphysema subtypes to enable exploration of new therapeutic targets, and sophisticated CT imaging methods will be integrated into clinical practice to achieve more personalized management.
    MeSH term(s) Bronchioles ; Humans ; Pulmonary Disease, Chronic Obstructive/diagnostic imaging ; Pulmonary Emphysema/diagnostic imaging ; X-Ray Microtomography
    Language English
    Publishing date 2021-10-06
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 639023-7
    ISSN 2005-6648 ; 1226-3303
    ISSN (online) 2005-6648
    ISSN 1226-3303
    DOI 10.3904/kjim.2021.124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Is High-Flow Nasal Cannula Oxygen Therapy an Aerosol-Generating Medical Procedure?

    Hamada, Satoshi / Tanabe, Naoya / Inoue, Hideki / Hirai, Toyohiro

    Archivos de bronconeumologia

    2022  Volume 57, Issue 9, Page(s) 601–602

    MeSH term(s) Aerosols ; Cannula ; Humans ; Oxygen ; Oxygen Inhalation Therapy/methods
    Chemical Substances Aerosols ; Oxygen (S88TT14065)
    Language English
    Publishing date 2022-06-08
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbr.2021.01.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Air Collection in the Intrathoracic Extrapleural Space-like Pneumothorax.

    Hamada, Satoshi / Tanabe, Naoya / Hirai, Toyohiro

    Internal medicine (Tokyo, Japan)

    2022  Volume 61, Issue 21, Page(s) 3311–3312

    MeSH term(s) Humans ; Pneumothorax/diagnostic imaging
    Language English
    Publishing date 2022-04-02
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 32371-8
    ISSN 1349-7235 ; 0021-5120 ; 0918-2918
    ISSN (online) 1349-7235
    ISSN 0021-5120 ; 0918-2918
    DOI 10.2169/internalmedicine.9347-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Editorial: The heterogeneity in COPD phenotypes.

    Tanabe, Naoya / Rhee, Chin Kook / Park, Hye Yun / Suzuki, Masaru

    Frontiers in medicine

    2022  Volume 9, Page(s) 982121

    Language English
    Publishing date 2022-08-15
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2022.982121
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Associations of fractional exhaled nitric oxide with airway dimension and mucus plugs on ultra-high-resolution computed tomography in former smokers and nonsmokers with asthma.

    Hayashi, Yusuke / Tanabe, Naoya / Matsumoto, Hisako / Shimizu, Kaoruko / Sakamoto, Ryo / Oguma, Tsuyoshi / Sunadome, Hironobu / Sato, Atsuyasu / Sato, Susumu / Hirai, Toyohiro

    Allergology international : official journal of the Japanese Society of Allergology

    2024  

    Abstract: Background: Associations of fractional exhaled nitric oxide (FeNO) with airway wall remodeling and mucus plugs remain to be explored in smokers and nonsmokers with asthma. Ultra-high-resolution computed tomography (U-HRCT), which allows accurate ... ...

    Abstract Background: Associations of fractional exhaled nitric oxide (FeNO) with airway wall remodeling and mucus plugs remain to be explored in smokers and nonsmokers with asthma. Ultra-high-resolution computed tomography (U-HRCT), which allows accurate structural quantification of airways >1 mm in diameter, was used in this study to examine whether higher FeNO was associated with thicker walls of the 3rd to 6th generation airways and mucus plugging in patients with asthma.
    Methods: The retrospective analyses included consecutive former smokers and nonsmokers with asthma who underwent U-HRCT in a hospital. The ratio of wall area to summed lumen and wall area was calculated as the wall area percent (WA%). Mucus plugging was visually scored.
    Results: Ninety-seven patients with asthma (including 59 former smokers) were classified into low (<20 ppb), middle (20-35 ppb), and high (>35 ppb) FeNO groups (n = 24, 26, and 47). In analysis including all patients and subanalysis including nonsmokers or former smokers, WA% in the 6th generation airways was consistently higher in the high FeNO group than in the low FeNO group, whereas WA% in the 3rd to 5th generation airways was not. In multivariable models, WA% in the 6th generation airways and the rate of mucus plugging were higher in the high FeNO group than in the low FeNO group after adjusting for age, sex, body mass index, smoking status, lung volume, and allergic rhinitis presence.
    Conclusions: Higher FeNO may reflect the inflammation and remodeling of relatively peripheral airways in asthma in both former smokers and nonsmokers.
    Language English
    Publishing date 2024-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1336498-4
    ISSN 1440-1592 ; 1323-8930
    ISSN (online) 1440-1592
    ISSN 1323-8930
    DOI 10.1016/j.alit.2024.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Is High-Flow Nasal Cannula Oxygen Therapy an Aerosol-Generating Medical Procedure?

    Hamada, Satoshi / Tanabe, Naoya / Inoue, Hideki / Hirai, Toyohiro

    Archivos de bronconeumologia

    2021  

    Language Spanish
    Publishing date 2021-02-03
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 2591346-3
    ISSN 2173-5751 ; 2173-5751
    ISSN (online) 2173-5751
    ISSN 2173-5751
    DOI 10.1016/j.arbres.2021.01.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Humidification via high-flow nasal cannula oxygen therapy does not generate aerosols.

    Hamada, Satoshi / Tanabe, Naoya / Hirai, Toyohiro

    British journal of anaesthesia

    2021  Volume 127, Issue 3, Page(s) e109–e110

    MeSH term(s) Administration, Intranasal ; Aerosols ; COVID-19/complications ; COVID-19/therapy ; Humans ; Humidity ; Nebulizers and Vaporizers ; Oxygen Inhalation Therapy/methods ; Particle Size ; Personal Protective Equipment
    Chemical Substances Aerosols
    Language English
    Publishing date 2021-06-30
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2021.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Effects of combined oxygen and surgical masks on inspired fraction of oxygen: relevance to COVID-19-induced respiratory failure.

    Hamada, Satoshi / Tanabe, Naoya / Hirai, Toyohiro

    British journal of anaesthesia

    2021  Volume 126, Issue 6, Page(s) e215–e217

    MeSH term(s) Adult ; COVID-19/metabolism ; COVID-19/therapy ; Female ; Humans ; Male ; Masks/adverse effects ; Oxygen/administration & dosage ; Oxygen/metabolism ; Oxygen Inhalation Therapy/methods ; Respiratory Insufficiency/metabolism ; Respiratory Insufficiency/therapy
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-03-05
    Publishing country England
    Document type Letter
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2021.02.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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