LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 16416

Search options

  1. Book ; Online: Crosstalk between Depression, Anxiety, and Dementia: Comorbidity in Behavioral Neurology and Neuropsychiatry

    Tanaka, Masaru

    2022  

    Keywords Medicine ; Clinical & internal medicine ; dementia ; behavioral and psychological symptoms of dementia ; systematic review ; meta-analysis ; animal-assisted intervention ; pet-robot intervention ; G protein-coupled receptors ; GPR120 ; FFAR4 ; schizophrenia ; polyunsaturated fatty acids ; long-chain fatty acids ; omega-3 ; nutritional psychiatry ; Alzheimer's disease ; psychiatric disease ; depression ; anxiety ; Down's syndrome ; inositol ; nutraceutical ; insulin signaling ; antioxidant ; aging ; psilocybin ; clinical trials ; oxidative stress ; redox ; multiple sclerosis ; biomarker ; neurodegenerative disease ; personalized medicine ; major depressive disorder ; longitudinal study ; LC-MS/MS ; plasma protein biomarker ; drug response monitoring ; multiple reaction monitoring ; diabetes mellitus ; type 2 ; dyslipidemias ; hypertension ; post-stroke depression ; disability level ; mortality ; late-life depression ; neuroimaging ; resting-state functional magnetic resonance imaging ; default mode network ; executive control network ; salience network ; healthy life expectancy (HALE) ; morbidity/mortality paradox ; cognition ; systolic blood pressure ; cerebral blood flow ; arterial properties ; angiogenesis ; gender medicine ; neurodegenerative disorders ; kisspeptin ; locomotion ; Kiss1 receptor ; HPA axis ; HPG axis ; nucleus accumbens ; stroke ; lipid ; diabetes
    Language 0|e
    Size 1 electronic resource (266 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021617796
    ISBN 9783036540023 ; 3036540024
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Book ; Online: Amyloid-β

    Tanaka, Masashi / Ono, Kenjiro / Saito, Satoshi

    Structure, Function, and Pathophysiological Significance in Neurodegenerative Diseases

    2023  

    Keywords Public health & preventive medicine ; activation phenotypes ; microglia ; neuroinflammation ; immunohistochemistry ; temporal cortex ; Alzheimer's disease ; amyloid ; amyloid β-protein (Aβ) ; mAb158 ; oligomers ; protofibrils ; amyloid aggregation ; supported lipid bilayers ; time-lapse AFM ; molecular dynamics simulation ; alzheimer's disease ; amyloid β ; bryostatin-1 ; ECE1 ; iPS ; nELAV ; neurotoxicity ; oligomer ; protein kinase C ; α-secretase ; APP mutation ; recessive inheritance ; familial Alzheimer's disease ; Aβ oligomers ; amyloid imaging ; microbiota ; bacterial amyloid ; FUBA ; curli ; CsgA ; amyloid beta ; oxidative stress ; supplement ; phosphodiesterase III inhibitor ; cerebral micro-hemorrhage(s) ; cerebral amyloid angiopathy ; amyloid-β protein ; transgenic mice ; NMR ; CD ; Aβ ; β-amyloid peptide ; α/β-discordant ; Dutch-type mutation ; E22Q ; FAD ; Amyloid β ; Polyphenol ; Pro-oxidant ; Alzheimer's Disease ; molecular imaging ; amyloid β-peptides ; islet amyloid polypeptide ; high-speed atomic force microscopy ; amyloid PET ; tau PET ; amyloid precursor protein ; mutation ; cerebellum ; PBB3 ; PiB ; axon ; traditional medicines ; Polygalae Radix ; diosgenin ; naringenin ; kihito ; amyloid-β ; antimicrobial ; antiviral ; antimicrobial peptide ; neurodegenerative disease ; misfolding ; fluorescence microscopy ; FRET ; n/a
    Language English
    Size 1 electronic resource (276 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030377034
    ISBN 9783036567136 ; 3036567135
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Book ; Online: Amyloid-β

    Tanaka, Masashi / Ono, Kenjiro / Saito, Satoshi

    2023  

    Keywords Research & information: general ; Biology, life sciences ; activation phenotypes ; microglia ; neuroinflammation ; immunohistochemistry ; temporal cortex ; Alzheimer's disease ; amyloid ; amyloid β-protein (Aβ) ; mAb158 ; oligomers ; protofibrils ; amyloid aggregation ; supported lipid bilayers ; time-lapse AFM ; molecular dynamics simulation ; alzheimer's disease ; amyloid β ; bryostatin-1 ; ECE1 ; iPS ; nELAV ; neurotoxicity ; oligomer ; protein kinase C ; α-secretase ; APP mutation ; recessive inheritance ; familial Alzheimer's disease ; Aβ oligomers ; amyloid imaging ; microbiota ; bacterial amyloid ; FUBA ; curli ; CsgA ; amyloid beta ; oxidative stress ; supplement ; phosphodiesterase III inhibitor ; cerebral micro-hemorrhage(s) ; cerebral amyloid angiopathy ; amyloid-β protein ; transgenic mice ; NMR ; CD ; Aβ ; β-amyloid peptide ; α/β-discordant ; Dutch-type mutation ; E22Q ; FAD ; Amyloid β ; Polyphenol ; Pro-oxidant ; Alzheimer's Disease ; molecular imaging ; amyloid β-peptides ; islet amyloid polypeptide ; high-speed atomic force microscopy ; amyloid PET ; tau PET ; amyloid precursor protein ; mutation ; cerebellum ; PBB3 ; PiB ; axon ; traditional medicines ; Polygalae Radix ; diosgenin ; naringenin ; kihito ; amyloid-β ; antimicrobial ; antiviral ; antimicrobial peptide ; neurodegenerative disease ; misfolding ; fluorescence microscopy ; FRET ; n/a
    Language English
    Size 1 electronic resource (276 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030374980
    ISBN 9783036567136 ; 3036567135
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Transcriptional and post-transcriptional regulation of genes encoding secretory proteins in Aspergillus oryzae.

    Tanaka, Mizuki

    Bioscience, biotechnology, and biochemistry

    2024  Volume 88, Issue 4, Page(s) 381–388

    Abstract: Aspergillus oryzae, also known as the yellow koji mold, produces various hydrolytic enzymes that are widely used in different industries. Its high capacity to produce secretory proteins makes this filamentous fungus a suitable host for heterologous ... ...

    Abstract Aspergillus oryzae, also known as the yellow koji mold, produces various hydrolytic enzymes that are widely used in different industries. Its high capacity to produce secretory proteins makes this filamentous fungus a suitable host for heterologous protein production. Amylolytic gene promoter is widely used to express heterologous genes in A. oryzae. The expression of this promoter is strictly regulated by several transcription factors, whose activation involves various factors. Furthermore, the expression levels of amylolytic and heterologous genes are post-transcriptionally regulated by mRNA degradation mechanisms in response to aberrant transcriptional termination or endoplasmic reticulum stress. This review discusses the transcriptional and post-transcriptional regulatory mechanisms controlling the expression of genes encoding secretory proteins in A. oryzae.
    MeSH term(s) Aspergillus oryzae/metabolism ; Endoplasmic Reticulum Stress ; Fungal Proteins/genetics ; Fungal Proteins/metabolism ; Gene Expression Regulation, Fungal ; Transcription Factors/metabolism
    Chemical Substances Fungal Proteins ; Transcription Factors
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1106450-x
    ISSN 1347-6947 ; 0916-8451
    ISSN (online) 1347-6947
    ISSN 0916-8451
    DOI 10.1093/bbb/zbae004
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4647: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Analytical evaluation of food quality.

    Tanaka, Mitsuru

    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

    2024  Volume 40, Issue 2, Page(s) 225–226

    MeSH term(s) Food Quality ; Food Contamination/analysis ; Food Analysis
    Language English
    Publishing date 2024-02-05
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 1483376-1
    ISSN 1348-2246 ; 1348-2246
    ISSN (online) 1348-2246
    ISSN 1348-2246
    DOI 10.1007/s44211-023-00494-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: [Perioperative management of patients treated with satralizumab].

    Tanaka, Masami

    Rinsho shinkeigaku = Clinical neurology

    2024  Volume 64, Issue 4, Page(s) 300–301

    MeSH term(s) Humans ; Perioperative Care ; Antibodies, Monoclonal, Humanized/administration & dosage
    Chemical Substances Antibodies, Monoclonal, Humanized
    Language Japanese
    Publishing date 2024-03-24
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 604200-4
    ISSN 1882-0654 ; 0009-918X
    ISSN (online) 1882-0654
    ISSN 0009-918X
    DOI 10.5692/clinicalneurol.cn-001935
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 1455: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 223: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Book ; Thesis: Molecular interaction of polyphenols with cytoskeleton and muscle proteins

    Tanaka, Mine

    2016  

    Author's details presented by M. Sc. Mine Tanaka
    Language English
    Size xii, 117 Seiten, Illustrationen, Diagramme
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruperto-Carola University of Heidelberg, 2016
    HBZ-ID HT019066949
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2016 E 1331 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Exploring the ethics of physical restraints: Students' questioning.

    Tanaka, Maki

    Nursing ethics

    2023  Volume 30, Issue 3, Page(s) 408–422

    Abstract: Background: Physical restraints are routinely employed to ensure patient safety in Japanese acute care. Little is known about nursing students' perspectives and how they begin to question their value and knowledge in the face of restraint experiences in ...

    Abstract Background: Physical restraints are routinely employed to ensure patient safety in Japanese acute care. Little is known about nursing students' perspectives and how they begin to question their value and knowledge in the face of restraint experiences in clinical practice.
    Objective: To investigate nursing students' questions about patient restraints and how they understand the ethics of the use of restraints in nursing.
    Research design: Qualitative descriptive research using narrative analysis.
    Participants and research context: Experiential data were generated and thematically analyzed from semi-structured interviews with 16 nursing students who had completed their bachelor's degree program requirements.
    Ethical considerations: The study was approved by academic and clinical ethics agencies. Participants provided written informed consent.
    Results: Physical restraints were encountered in 16 incidents, 3 with children and 13 with older patients with dementia. Students struggled to comprehend the policies and protocols of restraint use and worried their use was primarily for security rather than therapeutic purposes. Five themes were identified: (1). Questioning the tension between person-centered care, patient autonomy, and restraints, (2). Questioning the nature of restraints in which participants analyzed the policies and protocols around restraint use, (3). Questioning the professional nursing self whereby students reflected on how restraint use challenged their nursing values, and (4). Questioning professional nursing practice, in which students explored how restraints fit within a nursing perspective and positioned themselves as patient advocates. Students encountering physical restraints should ask questions based on values of patient-centeredness, autonomy, and advocacy. There is a need for education that facilitates reflection and questioning so that it informs students' ethical thinking which may enhance nurse advocacy to reduce restraint use.
    Conclusions: Restraints provide contexts in which students must face tensions between nursing values and clinical reality. Further research on nursing education strategies within non-psychiatric settings is needed to reduce physical restraints.
    MeSH term(s) Child ; Humans ; Restraint, Physical ; Education, Nursing ; Informed Consent ; Students, Nursing/psychology ; Qualitative Research
    Language English
    Publishing date 2023-01-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1200467-4
    ISSN 1477-0989 ; 0969-7330
    ISSN (online) 1477-0989
    ISSN 0969-7330
    DOI 10.1177/09697330221143149
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4041: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Applications of Synthetic Polymer Discoidal Lipid Nanoparticles to Biomedical Research.

    Tanaka, Masafumi

    Chemical & pharmaceutical bulletin

    2022  Volume 70, Issue 8, Page(s) 507–513

    Abstract: Liposomes are artificially prepared vesicular lipid nanoparticles with a bilayer structure, resembling cell membrane. Their ability to encapsulate various molecules along with excellent biocompatibility makes them ideal delivery vehicles for ... ...

    Abstract Liposomes are artificially prepared vesicular lipid nanoparticles with a bilayer structure, resembling cell membrane. Their ability to encapsulate various molecules along with excellent biocompatibility makes them ideal delivery vehicles for pharmaceuticals. They can also serve as platforms for membrane proteins to elucidate the structure and function in lipid membranes. Nascent high-density lipoproteins are discoidal lipid nanoparticles with a bilayer structure, which can be reconstituted with their constituents. Such reconstituted nanoparticles, nanodisks, were originally generated in terms of elucidation for mechanisms of lipoprotein metabolisms. At the same time, like liposomes, nanodisks have been developed as delivery vehicles and platforms for membrane proteins in structural biology. From a developmental background, apolipoproteins, their analogs, or fragment peptides were initially used as scaffolding molecules to wrap around the edge of the disk-shaped lipid bilayer. Since the discovery that styrene-maleic acid copolymers produce nanodisks instead of apolipoproteins, variously modified or novel polymers have been synthesized to broaden the applications of polymer nanodisks. This review provides an overview of the types of synthetic polymers used to produce nanodisks, and the biomedical applications of nanodisks to the developments of delivery vehicles and to the structural studies of membrane proteins.
    MeSH term(s) Apolipoproteins ; Biomedical Research ; Lipid Bilayers ; Liposomes ; Membrane Proteins ; Nanoparticles/chemistry ; Polymers/chemistry
    Chemical Substances Apolipoproteins ; Lipid Bilayers ; Lipid Nanoparticles ; Liposomes ; Membrane Proteins ; Polymers
    Language English
    Publishing date 2022-07-28
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 213307-6
    ISSN 1347-5223 ; 0009-2363
    ISSN (online) 1347-5223
    ISSN 0009-2363
    DOI 10.1248/cpb.c22-00125
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 770: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Orem's nursing self-care deficit theory: A theoretical analysis focusing on its philosophical and sociological foundation.

    Tanaka, Maki

    Nursing forum

    2022  Volume 57, Issue 3, Page(s) 480–485

    Abstract: Background: The self-care deficit nursing theory (SCDNT) advocated by Dorothea E. Orem is widely known and used in nursing practice worldwide. However, its broader philosophical and sociological context is often ignored.: Design: The theoretical ... ...

    Abstract Background: The self-care deficit nursing theory (SCDNT) advocated by Dorothea E. Orem is widely known and used in nursing practice worldwide. However, its broader philosophical and sociological context is often ignored.
    Design: The theoretical analysis of Orem's SCDNT reported in this article focuses on four aspects of the theory: its essential structure/core values, affirmation of nursing as a practical science, philosophical foundations, and the sociological context surrounding its development.
    Results: By interpreting the SCDNT from a philosophical and sociological viewpoint, it can be concluded that Orem established human-to-human nursing as a science premised on the existence of human beings as the central value of the theory. Moreover, Orem emphasized that the human-to-human relationship necessarily precedes the nurse-patient interface.
    Conclusion: The new interpretation and evaluation perspectives presented in this report may further the understanding of Orem's SCDNT. Moreover, they highlight the multifaceted aspects of nursing practice and role of person-to-person relationships as the basis of the SCDNT.
    MeSH term(s) Humans ; Nurse-Patient Relations ; Nursing Theory ; Self Care
    Language English
    Publishing date 2022-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 412336-0
    ISSN 1744-6198 ; 0029-6473
    ISSN (online) 1744-6198
    ISSN 0029-6473
    DOI 10.1111/nuf.12696
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 623: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top