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  1. Article ; Online: Fabrication of Mie-resonant silicon nanoparticles using laser annealing for surface-enhanced fluorescence spectroscopy.

    Fukuta, Tatsuya / Kato, Ryo / Tanaka, Takuo / Yano, Taka-Aki

    Microsystems & nanoengineering

    2024  Volume 10, Page(s) 45

    Abstract: Silicon nanostructures with unique Mie resonances have garnered considerable attention in the field of nanophotonics. Here, we present a simple and efficient method for the fabrication of silicon (Si) nanoparticle substrates using continuous-wave (CW) ... ...

    Abstract Silicon nanostructures with unique Mie resonances have garnered considerable attention in the field of nanophotonics. Here, we present a simple and efficient method for the fabrication of silicon (Si) nanoparticle substrates using continuous-wave (CW) laser annealing. The resulting silicon nanoparticles exhibit Mie resonances in the visible region, and their resonant wavelengths can be precisely controlled. Notably, laser-annealed silicon nanoparticle substrates show a 60-fold enhancement in fluorescence. This tunable and fluorescence-enhancing silicon nanoparticle platform has tremendous potential for highly sensitive fluorescence sensing and biomedical imaging applications.
    Language English
    Publishing date 2024-03-28
    Publishing country England
    Document type Journal Article
    ISSN 2055-7434
    ISSN (online) 2055-7434
    DOI 10.1038/s41378-024-00666-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Single-cell infrared vibrational analysis by optical trapping mid-infrared photothermal microscopy.

    Kato, Ryo / Yano, Taka-Aki / Tanaka, Takuo

    The Analyst

    2023  Volume 148, Issue 6, Page(s) 1285–1290

    Abstract: Single-cell analysis by means of vibrational spectroscopy combined with optical trapping is a reliable platform for unveiling cell-to-cell heterogeneities in vast populations. Although infrared (IR) vibrational spectroscopy provides rich molecular ... ...

    Abstract Single-cell analysis by means of vibrational spectroscopy combined with optical trapping is a reliable platform for unveiling cell-to-cell heterogeneities in vast populations. Although infrared (IR) vibrational spectroscopy provides rich molecular fingerprint information on biological samples in a label-free manner, its application with optical trapping has never been achieved due to weak gradient forces generated by the diffraction-limited focused IR beam and strong background of water absorption. Herein, we present single-cell IR vibrational analysis that incorporates mid-infrared photothermal (MIP) microscopy with optical trapping. Optically trapped single polymer particles and red blood cells (RBCs) in blood could be chemically identified owing to their IR vibrational fingerprints. This single-cell IR vibrational analysis further allowed us to probe the chemical heterogeneities of RBCs originating from the variation in the intracellular characteristics. Our demonstration paves the way for the IR vibrational analysis of single cells and chemical characterization in various fields.
    MeSH term(s) Microscopy/methods ; Optical Tweezers ; Spectrophotometry, Infrared/methods ; Polymers ; Single-Cell Analysis
    Chemical Substances Polymers
    Language English
    Publishing date 2023-03-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d2an01917e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Dynamic measurement of an angular Goos-Hänchen shift at a surface plasmon resonance in liquid.

    Olaya, Cherrie May / Hayazawa, Norihiko / Balgos, Maria Herminia / Tanaka, Takuo

    Applied optics

    2023  Volume 62, Issue 31, Page(s) 8426–8433

    Abstract: We developed a surface plasmon resonance (SPR)-enhanced angular Goos-Hänchen (GH) shift measurement system capable of tracking small refractive index changes with high sensitivity in a liquid environment. Our method can be performed in angular ... ...

    Abstract We developed a surface plasmon resonance (SPR)-enhanced angular Goos-Hänchen (GH) shift measurement system capable of tracking small refractive index changes with high sensitivity in a liquid environment. Our method can be performed in angular interrogation schemes, where we demonstrate a simple zero-finding algorithm to locate the SPR angle instead of the complicated data processing algorithms used in conventional sensors. We also propose a displacement interrogation scheme for dynamic measurement of small refractive index changes in the sample. The main advantage of our method is the controllability of the measured displacement by standard geometrical optics, allowing measurement sensitivity enhancement without the need to modify the sensor material.
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.501856
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: 3D conical helix metamaterial-based isotropic broadband perfect light absorber.

    Mudachathi, Renilkumar / Tanaka, Takuo

    Optics express

    2019  Volume 27, Issue 19, Page(s) 26369–26376

    Abstract: We present the design and fabrication of an isotropic broadband perfect light absorber in the near-infrared range using 3D metamaterials with a single resonator in the unit cell. The metamaterial resonator is comprised of a gold conical helix supported ... ...

    Abstract We present the design and fabrication of an isotropic broadband perfect light absorber in the near-infrared range using 3D metamaterials with a single resonator in the unit cell. The metamaterial resonator is comprised of a gold conical helix supported on a silicon pillar with back reflector realized on a silicon substrate. Simulations and experiments have demonstrated that the proposed absorber achieves a broad absorption band of more than 3 µm in the 1.5-4.5 µm wavelength range with an average absorbance of more than 90%. The numerical and experimental analyses show that the proposed device can provide both incident angle and polarization independent operations, which further widens the application prospects of our device.
    Language English
    Publishing date 2019-10-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.27.026369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Label-free visualization of photosynthetic microbial biofilms using mid-infrared photothermal and autofluorescence imaging.

    Kato, Ryo / Maeda, Kaisei / Yano, Taka-Aki / Tanaka, Kan / Tanaka, Takuo

    The Analyst

    2023  Volume 148, Issue 24, Page(s) 6241–6247

    Abstract: The formation of photosynthetic microbial biofilms comprising multispecies biomolecules, such as extracellular polymeric substances (EPSs), and microbial cells play pivotal roles in maintaining or stimulating their biological functions. Although there ... ...

    Abstract The formation of photosynthetic microbial biofilms comprising multispecies biomolecules, such as extracellular polymeric substances (EPSs), and microbial cells play pivotal roles in maintaining or stimulating their biological functions. Although there are numerous studies on photosynthetic microbial biofilms, the spatial distribution of EPS components that are vital for microbial biofilm formation, such as exopolysaccharides and proteins, is not well understood. Visualization of photosynthetic microbial biofilms requires label-free methods, because labelling EPSs results in structural changes or aggregation. Raman spectroscopy is useful for label-free visualization of biofilm constituents based on chemical contrast. However, interference resulting from the bright autofluorescence of photosynthetic molecules and the low detection efficiency of Raman scattering make visualization a challenge. Herein, we visualized photosynthetic microbial biofilms in a label-free manner using a super-resolution optical infrared absorption imaging technique, called mid-infrared photothermal (MIP) microscopy. By leveraging the advantages of MIP microscopy, such as its sub-micrometer spatial resolution, autofluorescence-free features, and high detection sensitivity, the distribution of cyanobacteria and their extracellular polysaccharides in the biofilm matrix were successfully visualized. This showed that cyanobacterial cells were aligned along acidic/sulfated polysaccharides in the extracellular environment. Furthermore, spectroscopic analyses elucidated that during formation of biofilms, sulfated polysaccharides initially form linear structures followed by entrapment of cyanobacterial cells. The present study provides the foundation for further studies on the formation, structure, and biological functions of microbial biofilms.
    MeSH term(s) Biofilms ; Polysaccharides ; Cyanobacteria ; Microscopy ; Optical Imaging
    Chemical Substances Polysaccharides
    Language English
    Publishing date 2023-12-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d3an01453c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Strengthen of magnetic anisotropy of Au/Co/Au nanostructure by surface plasmon resonance.

    Kikuchi, Yusuke / Tanaka, Takuo

    Scientific reports

    2019  Volume 9, Issue 1, Page(s) 8630

    Abstract: We experimentally demonstrated the increase of in-plane magnetic anisotropy in Au/Co/Au nanostructures by localized surface plasmon resonance (LSPR). When an array of Au/Co/Au square patch nanostructures was illuminated with linearly polarized light ... ...

    Abstract We experimentally demonstrated the increase of in-plane magnetic anisotropy in Au/Co/Au nanostructures by localized surface plasmon resonance (LSPR). When an array of Au/Co/Au square patch nanostructures was illuminated with linearly polarized light whose wavelength was 750 nm, the localized surface plasmons were resonantly excited in the nanostructures. From the measurement results of polar magneto-optical Kerr effect curves, we observed the magnetic anisotropy field increase in the Au/Co/Au nanostructure due to the excited surface plasmons. The in-plane magnetic anisotropy energy density was increased about 24%.
    Language English
    Publishing date 2019-06-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-019-45122-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Metamaterial perfect absorber simulations for intensifying the thermal gradient across a thermoelectric device.

    Katsumata, Shohei / Tanaka, Takuo / Kubo, Wakana

    Optics express

    2021  Volume 29, Issue 11, Page(s) 16396–16405

    Abstract: The thermal gradient across a thermoelectric device is the key to convert heat energy into electricity. Here, we propose a metamaterial perfect absorber (MPA) that increases the thermal gradient across a thermoelectric device by local heat generation ... ...

    Abstract The thermal gradient across a thermoelectric device is the key to convert heat energy into electricity. Here, we propose a metamaterial perfect absorber (MPA) that increases the thermal gradient across a thermoelectric device by local heat generation through absorbing thermal radiation emitted from an infinite-size blackbody radiator. The MPA, when attached on top of a bismuth telluride thermoelectric device, generates local heat that propagates to the device, resulting in an additional thermal gradient. The amount of local heat generated at the MPA and the output power of the thermoelectric device loaded with the MPA are examined through numerical calculations.
    Language English
    Publishing date 2021-06-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.418814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: High-sensitivity hyperspectral vibrational imaging of heart tissues by mid-infrared photothermal microscopy.

    Kato, Ryo / Yano, Taka-Aki / Minamikawa, Takeo / Tanaka, Takuo

    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

    2022  Volume 38, Issue 12, Page(s) 1497–1503

    Abstract: Visualizing the spatial distribution of chemical compositions in biological tissues is of great importance to study fundamental biological processes and origin of diseases. Raman microscopy, one of the label-free vibrational imaging techniques, has been ... ...

    Abstract Visualizing the spatial distribution of chemical compositions in biological tissues is of great importance to study fundamental biological processes and origin of diseases. Raman microscopy, one of the label-free vibrational imaging techniques, has been employed for chemical characterization of tissues. However, the low sensitivity of Raman spectroscopy often requires a long acquisition time of Raman measurement or a high laser power, or both, which prevents one from investigating large-area tissues in a nondestructive manner. In this work, we demonstrated chemical imaging of heart tissues using mid-infrared photothermal (MIP) microscopy that simultaneously achieves the high sensitivity benefited from IR absorption of molecules and the high spatial resolution down to a few micrometers. We successfully visualized the distributions of different biomolecules, including proteins, phosphate-including proteins, and lipids/carbohydrates/amino acids. Further, we experimentally compared MIP microscopy with Raman microscopy to evaluate the sensitivity and photodamage to tissues. We proved that MIP microscopy is a highly sensitive technique for obtaining vibrational information of molecules in a broad fingerprint region, thereby it could be employed for biological and diagnostic applications, such as live-tissue imaging.
    MeSH term(s) Microscopy/methods ; Spectrum Analysis, Raman/methods ; Vibration ; Proteins ; Lasers
    Chemical Substances Proteins
    Language English
    Publishing date 2022-09-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1483376-1
    ISSN 1348-2246 ; 1348-2246
    ISSN (online) 1348-2246
    ISSN 1348-2246
    DOI 10.1007/s44211-022-00182-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Bi-anisotropic Fano resonance in three-dimensional metamaterials.

    Moritake, Yuto / Tanaka, Takuo

    Scientific reports

    2018  Volume 8, Issue 1, Page(s) 9012

    Abstract: We experimentally investigated the bi-anisotropic properties of Fano resonance in three-dimensional (3D) metamaterials. Fano resonance in 3D metamaterials arises from the interference of in-phase and anti-phase modes that originate from mode ... ...

    Abstract We experimentally investigated the bi-anisotropic properties of Fano resonance in three-dimensional (3D) metamaterials. Fano resonance in 3D metamaterials arises from the interference of in-phase and anti-phase modes that originate from mode hybridization in coupled 3D split ring resonators (SRRs) with detuned resonant wavelengths. At Fano resonance, not only permittivity and permeability but also the bi-anisotropic parameter show doubly dispersive response. Manipulation of the bi-anisotropic response at Fano resonance was demonstrated through controlling the inversion symmetry of the 3D-SRRs. Improvement of inversion symmetry due to rotation of 3D-SRRs results in enhancement of magnetic response and inhibition of electric and bi-anisotropy responses at Fano resonance. Negligible electric and bi-anisotropic responses at Fano resonance were achieved due to the small radiative nature of the anti-phase mode. This bi-anisotropic Fano metamaterials with rich and tunable bi-anisotropy will extend the capabilities of new optical phenomena and broaden the applications of bi-anisotropic metamaterials.
    Language English
    Publishing date 2018-06-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-018-27404-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Impact of substrate etching on plasmonic elements and metamaterials: preventing red shift and improving refractive index sensitivity.

    Moritake, Yuto / Tanaka, Takuo

    Optics express

    2018  Volume 26, Issue 3, Page(s) 3674–3683

    Abstract: We propose and demonstrate the elimination of substrate influence on plasmon resonance by using selective and isotropic etching of substrates. Preventing the red shift of the resonance due to substrates and improving refractive index sensitivity were ... ...

    Abstract We propose and demonstrate the elimination of substrate influence on plasmon resonance by using selective and isotropic etching of substrates. Preventing the red shift of the resonance due to substrates and improving refractive index sensitivity were experimentally demonstrated by using plasmonic nanostructures fabricated on silicon substrates. Applying substrate etching decreases the effective refractive index around the metal nanostructures, resulting in elimination of the red shift. Improvement of sensitivity to the refractive index environment was demonstrated by using plasmonic metamaterials with Fano resonance based on far field interference. Change in quality factors (Q-factors) of the Fano resonance by substrate etching was also investigated in detail. The presence of a closely positioned substrate distorts the electric field distribution and degrades the Q-factors. Substrate etching dramatically increased the refractive index sensitivity reaching to 1532 nm/RIU since the electric fields under the nanostructures became accessible through substrate etching. The FOM was improved compared to the case without the substrate etching. The method presented in this paper is applicable to a variety of plasmonic structures to eliminate the influence of substrates for realizing high performance plasmonic devices.
    Language English
    Publishing date 2018-02-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.26.003674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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