LIVIVO - Search results -

Search results

Result 1 - 10 of total 364

Search options

Article ; Online: Getting closer to the clinic.

Tanaka, Toshiko / Ferrucci, Luigi

2022 Volume 11

Abstract: Associations between plasma protein levels and DNA methylation patterns can be used to predict the onset of age-related chronic disease. ...

Abstract	Associations between plasma protein levels and DNA methylation patterns can be used to predict the onset of age-related chronic disease.
MeSH term(s)	Aging/genetics ; Chronic Disease ; DNA Methylation ; Epigenesis, Genetic ; Humans
Language	English
Publishing date	2022-02-25
Publishing country	England
Document type	Journal Article ; Comment
ZDB-ID	2687154-3
ISSN	2050-084X ; 2050-084X
ISSN (online)	2050-084X
ISSN	2050-084X
DOI	10.7554/eLife.77180
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: A Dietary Holy Grail for Healthy Aging?

Tanaka, Toshiko / Simonsick, Eleanor / Ferrucci, Luigi

The journals of gerontology. Series A, Biological sciences and medical sciences

2023 Volume 78, Issue 2, Page(s) 239–240

MeSH term(s)	Healthy Aging ; Diet
Language	English
Publishing date	2023-02-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Intramural ; Comment
ZDB-ID	1223643-3
ISSN	1758-535X ; 1079-5006
ISSN (online)	1758-535X
ISSN	1079-5006
DOI	10.1093/gerona/glac219
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uc I Zs.242/A: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Associations between dietary indices and hearing status among middle-older aged adults - results from the Baltimore Longitudinal Study of Aging.

Jin, Yichen / Tanaka, Toshiko / Reed, Nicholas S / Tucker, Katherine L / Ferrucci, Luigi / Talegawkar, Sameera A

The American journal of clinical nutrition

2024

Abstract: Background: Hearing loss, a public health issue in older populations, is closely related to functional decline.: Objective: To investigate the longitudinal associations between 4 dietary indices and hearing status.: Methods: Data from the ... ...

Abstract	Background: Hearing loss, a public health issue in older populations, is closely related to functional decline. Objective: To investigate the longitudinal associations between 4 dietary indices and hearing status. Methods: Data from the Baltimore Longitudinal Study of Aging were used and included 882 participants ≥45 y of age. Dietary intake was assessed using a validated food frequency questionnaire, and 4 dietary scores (Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay diet [MIND], Mediterranean style diet score [MDS], Alternative Healthy Eating Index [AHEI], and Healthy Eating Index [HEI]) were calculated as averages over time. Hearing status was examined using pure-tone audiometry, and pure-tone average (PTA) of hearing thresholds were calculated at speech-level (PTA Results: At baseline, the mean age of participants was 67 y and 55% were female. Over a median of 8 y of follow-up, MDS ≥7 was associated with 3.5 (95% CI: -6.5, -0.4) and 5.0 (95% CI: -9.1, -1.0) dB lower PTA Conclusions: Adherence to healthy dietary patterns was associated with better hearing status, with stronger associations at high frequencies. Am J Clin Nutr 20xx;x:xx.
Language	English
Publishing date	2024-03-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	280048-2
ISSN	1938-3207 ; 0002-9165
ISSN (online)	1938-3207
ISSN	0002-9165
DOI	10.1016/j.ajcnut.2024.03.001
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ue I Zs.208: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Gender differences in guilt aversion in Korea and the United Kingdom.

Nihonsugi, Tsuyoshi / Tanaka, Toshiko / Haruno, Masahiko

Scientific reports

2022 Volume 12, Issue 1, Page(s) 8187

Abstract: Guilt aversion, which describes the tendency to reduce the discrepancy between a partner's expectation and his/her actual outcome, is a key driving force for cooperation in both the East and West. A recent study based on functional magnetic resonance ... ...

Abstract	Guilt aversion, which describes the tendency to reduce the discrepancy between a partner's expectation and his/her actual outcome, is a key driving force for cooperation in both the East and West. A recent study based on functional magnetic resonance imaging and online behavioral experiments reported that men show stronger guilt aversion than women and also suggested that men's predominance in guilt aversion arises from stronger sensitivity to social norms. However, since the participants of that study were all Japanese, it remains unaddressed how common the gender difference in guilt aversion is. Here, we conducted online behavioral studies on people from Korea and the UK (Korea; n = 294, UK; n = 347) using the same trust game. We confirmed that men exhibit stronger guilt aversion than women in both countries. Furthermore, consistent with the Japanese study, our Lasso regression analysis for UK participants revealed that Big Five Conscientiousness (rule-based decision) correlated with guilt aversion in men. In contrast, guilt aversion in Korean men correlated with Big Five Neuroticism. Thus, our results suggest that gender differences in guilt aversion are universal but the underlying cognitive processes may be influenced by cultural differences.
MeSH term(s)	Affect ; Female ; Guilt ; Humans ; Magnetic Resonance Imaging ; Male ; Sex Factors ; Trust
Language	English
Publishing date	2022-05-17
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-12163-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The initial decrease in 7T-BOLD signals detected by hyperalignment contains information to decode facial expressions.

Tanaka, Toshiko / Okamoto, Naohiro / Kida, Ikuhiro / Haruno, Masahiko

NeuroImage

2022 Volume 262, Page(s) 119537

Abstract: The initial decrease in the blood oxygenation level-dependent (BOLD) signal reflects primary neuronal activity more than the later hemodynamic positive peak responses. Moreover, ultra-high field BOLD has high sensitivity for the initial de-oxygenation ... ...

Abstract	The initial decrease in the blood oxygenation level-dependent (BOLD) signal reflects primary neuronal activity more than the later hemodynamic positive peak responses. Moreover, ultra-high field BOLD has high sensitivity for the initial de-oxygenation signal. However, it is not fully understood how much information about task events and cognitive processes the initial decrease in the BOLD signal contains. Multivoxel pattern analysis (MVPA) of the BOLD signal has enabled the quantification of information contained in the activity patterns, but it has mainly relied on the positive peak responses. Here, we applied a signal-based functional inter-individual alignment algorithm (i.e., hyper-alignment) to a 7T-BOLD timeseries scanned while participants conducted a facial expression discrimination task. We found that the MVPA decoding accuracy in the bilateral amygdala 2 s after the face onset was significantly beyond chance. Furthermore, we confirmed that the voxels contributing to the decoding accuracy at 2 s displayed a decreasing hemodynamics response. These results demonstrated that the initial decrease in 7T-BOLD signals contains finer information about task events and cognitive processes than thought previously.
MeSH term(s)	Algorithms ; Brain/physiology ; Brain Mapping/methods ; Facial Expression ; Hemodynamics ; Humans ; Magnetic Resonance Imaging/methods ; Oxygen
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2022-08-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1147767-2
ISSN	1095-9572 ; 1053-8119
ISSN (online)	1095-9572
ISSN	1053-8119
DOI	10.1016/j.neuroimage.2022.119537
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3664: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 7: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A case of sudden cardiac death due to mitochondrial disease.

Yoshida, Kosho / Sato, Hiroaki / Kimura, Satoshi / Tanaka, Toshiko / Kasai, Kentaro

Legal medicine (Tokyo, Japan)

2022 Volume 55, Page(s) 102026

Abstract: A 25-year-old, emaciated man without medical treatment was found to have died suddenly at home by his mother. At autopsy, there were no injuries to his body, but significant circulatory insufficiency was observed. Electron microscopy revealed abnormal ... ...

Abstract	A 25-year-old, emaciated man without medical treatment was found to have died suddenly at home by his mother. At autopsy, there were no injuries to his body, but significant circulatory insufficiency was observed. Electron microscopy revealed abnormal mitochondria in cells of the cardiac conduction system. The conduction system was filled with mitochondrial size abnormalities and mitochondrial cristae abnormalities. No notable abnormal findings were observed in other organs. Genetic examination of the blood revealed the mitochondrial pathogenetic variant m.3243A>G. Epileptic seizures, diabetic ketoacidosis, and hyperosmolar hyperglycemic state were unlikely to be the cause of sudden death. The cause of death was diagnosed as arrhythmia possibly induced by the failure of the cardiac conduction system due to mitochondrial disease. This is a rare case of sudden death caused by an accumulation of abnormal mitochondria in the cardiac conduction system.
MeSH term(s)	Adult ; Autopsy ; Death, Sudden, Cardiac/etiology ; Humans ; Male ; Mitochondria ; Mitochondrial Diseases/complications ; Mitochondrial Diseases/genetics
Language	English
Publishing date	2022-01-22
Publishing country	Ireland
Document type	Case Reports ; Journal Article
ZDB-ID	2019555-2
ISSN	1873-4162 ; 1344-6223
ISSN (online)	1873-4162
ISSN	1344-6223
DOI	10.1016/j.legalmed.2022.102026
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5250: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Autopsy case of fatal hypoglycemia following ingestion of a therapeutic dose of tramadol.

Yoshida, Kosho / Sato, Hiroaki / Tanaka, Toshiko / Kasai, Kentaro

Forensic science, medicine, and pathology

2021 Volume 17, Issue 3, Page(s) 465–468

Abstract: An 86-year-old female was found unconscious the day after taking a prescribed tablet containing a combination of tramadol and acetaminophen. At admission to the hospital, marked hypoglycemia (blood glucose: 4 mg/dL) was confirmed, but serum insulin and C- ...

Abstract	An 86-year-old female was found unconscious the day after taking a prescribed tablet containing a combination of tramadol and acetaminophen. At admission to the hospital, marked hypoglycemia (blood glucose: 4 mg/dL) was confirmed, but serum insulin and C-peptide were within the normal range, which suggested that neither endogenous hyperinsulinemia nor exogenous insulin administration was responsible for the hypoglycemia. Despite resuscitation efforts, the woman subsequently died. At autopsy, there was renal disorder, but any pathological abnormalities that could have caused hypoglycemia were not observed. Blood tramadol and acetaminophen were in the therapeutic range. We speculate that the cause of fatal hypoglycemia was tramadol intake at the therapeutic dose. Older age and renal insufficiency are factors that could have potentially caused the fatal hypoglycemia in this case despite tramadol having been taken at a therapeutic dose. This is the first case report of fatal hypoglycemia following ingestion of a therapeutic dose of tramadol.
MeSH term(s)	Aged, 80 and over ; Analgesics, Opioid/adverse effects ; Autopsy ; Eating ; Female ; Humans ; Hypoglycemia/chemically induced ; Tramadol/adverse effects
Chemical Substances	Analgesics, Opioid ; Tramadol (39J1LGJ30J)
Language	English
Publishing date	2021-06-09
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2195904-3
ISSN	1556-2891 ; 1547-769X
ISSN (online)	1556-2891
ISSN	1547-769X
DOI	10.1007/s12024-021-00386-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

Order via subito

Details ▾
- Full text online
- Order with fees

Article: The Role of Brain Methamidophos in Acephate Poisoning in Mice.

Tanaka, Toshiko / Sato, Hiroaki / Yoshida, Kosho / Kasai, Kentaro

Journal of UOEH

2021 Volume 43, Issue 2, Page(s) 197–203

Abstract: We gave mice a 540 mg/kg dose of LD50 acephate, followed by an assessment of acephate, methamidophos (MP), and choline esterase (ChE) activity for up to 4 hours (hr) in order to investigate the time course of acephate intoxication. At 1 hr, the blood ... ...

Abstract	We gave mice a 540 mg/kg dose of LD50 acephate, followed by an assessment of acephate, methamidophos (MP), and choline esterase (ChE) activity for up to 4 hours (hr) in order to investigate the time course of acephate intoxication. At 1 hr, the blood acephate and MP levels were 428 ± 90 µg/ml (mean ± SEM) and 4.2 ± 0.4 µg/ ml, respectively. The liver acephate levels were similar to those in the blood, but the liver MP levels were approximately 3.5 times that of the blood at 1 hr. The brain MP level tended to be higher than the blood MP at 1 hr. These levels decreased gradually over 4 hr, but the brain acephate and MP levels surpassed the blood levels significantly at 4 hr, and after 2 hr, respectively. Serum, liver, cerebrum, cerebellum, and brainstem cholinesterase activity (ChE) were inhibited at 1 hr, and remained inhibited in all but the cerebellum until the end of the experiment. The obtained data were applied to previously reported autopsy cases of acephate intake. Experimental data suggest that brain MP is involved in acute acephate-induced poisoning, even after a reduction in blood acephate. In autopsy cases with suspected acephate poisoning, the MP level in the brain should be considered in addition to the ChE activity to diagnose the cause of death.
MeSH term(s)	Animals ; Brain ; Cholinesterase Inhibitors ; Insecticides ; Mice ; Organothiophosphorus Compounds ; Phosphoramides
Chemical Substances	Cholinesterase Inhibitors ; Insecticides ; Organothiophosphorus Compounds ; Phosphoramides ; acephate (3Y417O444D) ; methamidophos (8Z083FM94W)
Language	English
Publishing date	2021-06-07
Publishing country	Japan
Document type	Journal Article
ZDB-ID	632724-2
ISSN	2187-2864 ; 0387-821X
ISSN (online)	2187-2864
ISSN	0387-821X
DOI	10.7888/juoeh.43.197
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 2868: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A message of the majority with scientific evidence encourages young people to show their prosocial nature in COVID-19 vaccination.

Tanaka, Toshiko / Nihonsugi, Tsuyoshi / Ohtake, Fumio / Haruno, Masahiko

Scientific reports

2021 Volume 11, Issue 1, Page(s) 23261

Abstract: The most promising way to prevent the explosive spread of COVID-19 infection is to achieve herd immunity through vaccination. It is therefore important to motivate those who are less willing to be vaccinated. To address this issue, we conducted an online ...

Abstract	The most promising way to prevent the explosive spread of COVID-19 infection is to achieve herd immunity through vaccination. It is therefore important to motivate those who are less willing to be vaccinated. To address this issue, we conducted an online survey of 6232 Japanese people to investigate age- and gender-dependent differences in attitudes towards COVID-19 vaccination and the underlying psychological processes. We asked participants to read one of nine different messages about COVID-19 vaccination and rate their willingness to be vaccinated. We also collected their 17 social personality trait scores and demographic information. We found that males 10-20 years old were least willing to be vaccinated. We also found that prosocial traits are the driving force for young people, but the motivation in older people also depends on risk aversion and self-interest. Furthermore, an analysis of 9 different messages demonstrated that for young people (particularly males), the message emphasizing the majority's intention to vaccinate and scientific evidence for the safety of the vaccination had the strongest positive effect on the willingness to be vaccinated, suggesting that the "majority + scientific evidence" message nudges young people to show their prosocial nature in action.
MeSH term(s)	Adolescent ; Adult ; COVID-19/prevention & control ; COVID-19/psychology ; COVID-19/virology ; COVID-19 Vaccines ; Decision Support Techniques ; Evidence-Based Medicine ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Immunity, Herd ; Male ; Middle Aged ; Motivation ; SARS-CoV-2/isolation & purification ; Social Behavior ; Surveys and Questionnaires ; Vaccination/adverse effects ; Vaccination/psychology ; Young Adult
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2021-12-01
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-02230-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Butane detection after long-term treatment of burns in two autopsy cases.

Tanaka, Toshiko / Kasai, Kentaro / Yoshida, Kosho / Sato, Hiroaki

Legal medicine (Tokyo, Japan)

2021 Volume 49, Page(s) 101847

Abstract: A man and a woman were rescued from a room that had exploded. Many empty cassette gas cylinders were found in the room. The man and woman were hospitalized immediately for the treatment of burns. The woman died 6 days later, and the man died 31 days ... ...

Abstract	A man and a woman were rescued from a room that had exploded. Many empty cassette gas cylinders were found in the room. The man and woman were hospitalized immediately for the treatment of burns. The woman died 6 days later, and the man died 31 days later without regaining consciousness. Carbonization and hardening of the frontal facial skin and parts of the left and right fingers were observed on the man's body. In both cases, systemic burns had led to progressive systemic edema and markedly suppressed circulation. Analytical samples for butanes obtained from their bodies at autopsy were stored at -20 °C for 14 and 25 days, respectively, before analysis. Normal butane and isobutane were quantified in the brain and subcutaneous adipose tissue of the woman. Only the isobutane was quantified in the adipose tissue of the man. The evidence suggests that the man lit a cigarette while breathing gas and the entire room exploded. Our results also suggest that butane can be detected in the adipose tissue of autopsy cases long after inhalation even under the present storage conditions, and isobutane may remain in adipose tissue longer than n-butane.
MeSH term(s)	Adipose Tissue/metabolism ; Adult ; Autopsy/methods ; Burns/complications ; Burns/metabolism ; Burns/pathology ; Butanes/analysis ; Cerebral Cortex/metabolism ; Edema/etiology ; Edema/pathology ; Fatal Outcome ; Female ; Forensic Medicine/methods ; Humans ; Male ; Middle Aged ; Time Factors ; Tissue Preservation/methods
Chemical Substances	Butanes ; butane (6LV4FOR43R)
Language	English
Publishing date	2021-01-13
Publishing country	Ireland
Document type	Case Reports ; Journal Article
ZDB-ID	2019555-2
ISSN	1873-4162 ; 1344-6223
ISSN (online)	1873-4162
ISSN	1344-6223
DOI	10.1016/j.legalmed.2021.101847
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5250: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito