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Article: Herbal product use patterns and possible herb-drug interactions among older adults in Turkey

Taneri, Petek Eylul / Akis, Nalan / Karaalp, Atila

Journal of herbal medicine. 2021 Oct., v. 29

2021

Abstract: Traditional and Complementary medicine use is on the increase universally. In this descriptive study, the aim is to evaluate the frequency and determinants of herbal product use, as well as determine possible drug-herb interactions among older ... ...

Abstract	Traditional and Complementary medicine use is on the increase universally. In this descriptive study, the aim is to evaluate the frequency and determinants of herbal product use, as well as determine possible drug-herb interactions among older individuals who live in rural and urban areas.The study was carried out with individuals 65 years or older in one urban and five rural neighborhoods in Bursa, Turkey. The data was collected during face-to-face interviews using a questionnaire comprising 43 questions. The participants were asked about the drugs and herb/herbal products they use and then the possible drug-herb interactions were evaluated using Micromedex®.Among the participants, 82.2 % reported using at least one drug regularly, and 18.3 % used at least one herb/herbal product in the past year (rural 26.1 %, urban 13.4 %). Most commonly used herb/herbal products were plane tree leaves and black cumin. Herbal product use was seen more among those experiencing difficulties accessing health care and living alone. Among those using drug and herb/herbal products concurrently, the possible drug-herb interaction rate was 7.5 %.Physicians providing health care services to geriatric populations should inquire about usage of drugs and herbs. Conventional medicine should be made accessible to every older adult, and it should be ensured that they do not have to resort to complementary therapies that could harm their health.
Keywords	Nigella sativa ; alternative medicine ; descriptive studies ; health services ; herbal medicines ; medicine ; questionnaires ; trees
Language	English
Dates of publication	2021-10
Publishing place	Elsevier GmbH
Document type	Article
ISSN	2210-8033
DOI	10.1016/j.hermed.2021.100487
Database	NAL-Catalogue (AGRICOLA)

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Article: A 7-Step Guideline for Qualitative Synthesis and Meta-Analysis of Observational Studies in Health Sciences.

Glisic, Marija / Raguindin, Peter Francis / Gemperli, Armin / Taneri, Petek Eylul / Salvador, Dante Jr / Voortman, Trudy / Marques Vidal, Pedro / Papatheodorou, Stefania I / Kunutsor, Setor K / Bano, Arjola / Ioannidis, John P A / Muka, Taulant

Public health reviews

2023 Volume 44, Page(s) 1605454

Abstract: Objectives: ...

Abstract	Objectives:
Language	English
Publishing date	2023-05-16
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	217531-9
ISSN	2107-6952 ; 0301-0422
ISSN (online)	2107-6952
ISSN	0301-0422
DOI	10.3389/phrs.2023.1605454
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Article ; Online: Protocol for the development of a core outcome set for neonatal sepsis (NESCOS).

Taneri, Petek Eylul / Kirkham, Jamie J / Molloy, Eleanor J / Biesty, Linda / Polin, Richard A / Wynn, James L / Stoll, Barbara J / Kissoon, Niranjan / Kawaza, Kondwani / Daly, Mandy / Branagan, Aoife / Bonnard, Lívia Nagy / Giannoni, Eric / Strunk, Tobias / Ohaja, Magdalena / Mugabe, Kenneth / Suguitani, Denise / Quirke, Fiona / Devane, Declan

PloS one

2023 Volume 18, Issue 12, Page(s) e0295325

Abstract: Neonatal sepsis is a serious public health problem; however, there is substantial heterogeneity in the outcomes measured and reported in research evaluating the effectiveness of the treatments. Therefore, we aim to develop a Core Outcome Set (COS) for ... ...

Abstract	Neonatal sepsis is a serious public health problem; however, there is substantial heterogeneity in the outcomes measured and reported in research evaluating the effectiveness of the treatments. Therefore, we aim to develop a Core Outcome Set (COS) for studies evaluating the effectiveness of treatments for neonatal sepsis. Since a systematic review of key outcomes from randomised trials of therapeutic interventions in neonatal sepsis was published recently, we will complement this with a qualitative systematic review of the key outcomes of neonatal sepsis identified by parents, other family members, parent representatives, healthcare providers, policymakers, and researchers. We will interpret the outcomes of both studies using a previously established framework. Stakeholders across three different groups i.e., (1) researchers, (2) healthcare providers, and (3) patients' parents/family members and parent representatives will rate the importance of the outcomes in an online Real-Time Delphi Survey. Afterwards, consensus meetings will be held to agree on the final COS through online discussions with key stakeholders. This COS is expected to minimize outcome heterogeneity in measurements and publications, improve comparability and synthesis, and decrease research waste.
MeSH term(s)	Infant, Newborn ; Humans ; Neonatal Sepsis/therapy ; Research Design ; Delphi Technique ; Consensus ; Outcome Assessment, Health Care/methods ; Treatment Outcome ; Systematic Reviews as Topic
Language	English
Publishing date	2023-12-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0295325
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Buckwheat and Cardiometabolic Health: A Systematic Review and Meta-Analysis.

Llanaj, Erand / Ahanchi, Noushin Sadat / Dizdari, Helga / Taneri, Petek Eylul / Niehot, Christa D / Wehrli, Faina / Khatami, Farnaz / Raeisi-Dehkordi, Hamidreza / Kastrati, Lum / Bano, Arjola / Glisic, Marija / Muka, Taulant

Journal of personalized medicine

2022 Volume 12, Issue 12

Abstract: Buckwheat (BW) is suggested to have beneficial effects, but evidence on how it affects cardiometabolic health (CMH) is not yet established. We aimed to assess the effects of BW and/or its related bioactive compounds on cardiovascular disease (CVD) risk ... ...

Abstract	Buckwheat (BW) is suggested to have beneficial effects, but evidence on how it affects cardiometabolic health (CMH) is not yet established. We aimed to assess the effects of BW and/or its related bioactive compounds on cardiovascular disease (CVD) risk markers in adults. Five databases were searched for eligible studies. Observational prospective studies, nonrandomized or randomized trials were considered if they assessed BW, rutin or quercetin-3-glucoside intake and CVD risk markers. We adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for reporting. We selected 16 human studies based on 831 subjects with mild metabolic disturbances, such as hypercholesterolemia, diabetes and/or overweight. Eight studies, investigating primarily grain components, were included in the meta-analyses (
Language	English
Publishing date	2022-11-22
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm12121940
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Article ; Online: A 7-Step Guideline for Qualitative Synthesis and Meta-Analysis of Observational Studies in Health Sciences

Glisic, Marija / Raguindin, Peter Francis / Gemperli, Armin / Taneri, Petek Eylul / Salvador, Dante Jr / Voortman, Trudy / Marques Vidal, Pedro / Papatheodorou, Stefania I. / Kunutsor, Setor K. / Bano, Arjola / Ioannidis, John P.A. / Muka, Taulant

Public Health Reviews

2023 Volume 44

Abstract: Objectives: To provide a step-by-step, easy-to-understand, practical guide for systematic review and meta-analysis of observational studies. Methods: A multidisciplinary team of researchers with extensive experience in observational studies and ... ...

Abstract	Objectives: To provide a step-by-step, easy-to-understand, practical guide for systematic review and meta-analysis of observational studies. Methods: A multidisciplinary team of researchers with extensive experience in observational studies and systematic review and meta-analysis was established. Previous guidelines in evidence synthesis were considered. Results: There is inherent variability in observational study design, population, and analysis, making evidence synthesis challenging. We provided a framework and discussed basic meta-analysis concepts to assist reviewers in making informed decisions. We also explained several statistical tools for dealing with heterogeneity, probing for bias, and interpreting findings. Finally, we briefly discussed issues and caveats for translating results into clinical and public health recommendations. Our guideline complements “A 24-step guide on how to design, conduct, and successfully publish a systematic review and meta-analysis in medical research” and addresses peculiarities for observational studies previously unexplored. Conclusion: We provided 7 steps to synthesize evidence from observational studies. We encourage medical and public health practitioners who answer important questions to systematically integrate evidence from observational studies and contribute evidence-based decision-making in health sciences.
Keywords	cohort studies ; cross-sectional studies ; evidence-based approach ; observational study ; systematic review and meta-analysis
Subject code	306
Language	English
Publishing country	nl
Document type	Article ; Online
ZDB-ID	217531-9
ISSN	2107-6952 ; 0301-0422
ISSN (online)	2107-6952
ISSN	0301-0422
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Association Between Ultra-Processed Food Intake and All-Cause Mortality: A Systematic Review and Meta-Analysis.

Taneri, Petek Eylul / Wehrli, Faina / Roa-Díaz, Zayne M / Itodo, Oche Adam / Salvador, Dante / Raeisi-Dehkordi, Hamidreza / Bally, Lia / Minder, Beatrice / Kiefte-de Jong, Jessica C / Laine, Jessica E / Bano, Arjola / Glisic, Marija / Muka, Taulant

American journal of epidemiology

2022 Volume 191, Issue 7, Page(s) 1323–1335

Abstract: Consumption of ultra-processed foods (UPF) has increased worldwide during the last decades because they are hyperpalatable, cheap, and ready-to-consume products. However, uncertainty exists about their impact on health. We conducted a systematic review ... ...

Abstract	Consumption of ultra-processed foods (UPF) has increased worldwide during the last decades because they are hyperpalatable, cheap, and ready-to-consume products. However, uncertainty exists about their impact on health. We conducted a systematic review and meta-analysis evaluating the association of UPF consumption with all-cause mortality risk. Five bibliographic databases were searched for relevant studies. Random effects models were used to calculate pooled relative risks (RRs) and 95% confidence intervals (CIs). Of 6,951 unique citations, 40 unique prospective cohort studies comprising 5,750,133 individuals were included; publication dates ranged from 1984 to 2021. Compared with low consumption, highest consumption of UPF (RR = 1.29, 95% CI: 1.17, 1.42), sugar-sweetened beverages (RR = 1.11, 95% CI, 1.04, 1.18), artificially sweetened beverages (RR = 1.14, 95% CI, 1.05, 1.22), and processed meat/red meat (RR = 1.15, 95% CI, 1.10, 1.21) were significantly associated with increased risk of mortality. However, breakfast cereals were associated with a lower mortality risk (RR = 0.85, 95% CI, 0.79, 0.92). This meta-analysis suggests that high consumption of UPF, sugar-sweetened beverages, artificially sweetened beverages, processed meat, and processed red meat might increase all-cause mortality, while breakfast cereals might decrease it. Future studies are needed to address lack of standardized methods in UPF categorization.
MeSH term(s)	Eating ; Fast Foods/adverse effects ; Humans ; Meat ; Prospective Studies ; Sweetening Agents/adverse effects
Chemical Substances	Sweetening Agents
Language	English
Publishing date	2022-02-26
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	2937-3
ISSN	1476-6256 ; 0002-9262
ISSN (online)	1476-6256
ISSN	0002-9262
DOI	10.1093/aje/kwac039
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Article ; Online: Prognostic models in COVID-19 infection that predict severity: a systematic review.

Buttia, Chepkoech / Llanaj, Erand / Raeisi-Dehkordi, Hamidreza / Kastrati, Lum / Amiri, Mojgan / Meçani, Renald / Taneri, Petek Eylul / Ochoa, Sergio Alejandro Gómez / Raguindin, Peter Francis / Wehrli, Faina / Khatami, Farnaz / Espínola, Octavio Pano / Rojas, Lyda Z / de Mortanges, Aurélie Pahud / Macharia-Nimietz, Eric Francis / Alijla, Fadi / Minder, Beatrice / Leichtle, Alexander B / Lüthi, Nora /

Ehrhard, Simone / Que, Yok-Ai / Fernandes, Laurenz Kopp / Hautz, Wolf / Muka, Taulant

European journal of epidemiology

2023 Volume 38, Issue 4, Page(s) 355–372

Abstract: Current evidence on COVID-19 prognostic models is inconsistent and clinical applicability remains controversial. We performed a systematic review to summarize and critically appraise the available studies that have developed, assessed and/or validated ... ...

Abstract	Current evidence on COVID-19 prognostic models is inconsistent and clinical applicability remains controversial. We performed a systematic review to summarize and critically appraise the available studies that have developed, assessed and/or validated prognostic models of COVID-19 predicting health outcomes. We searched six bibliographic databases to identify published articles that investigated univariable and multivariable prognostic models predicting adverse outcomes in adult COVID-19 patients, including intensive care unit (ICU) admission, intubation, high-flow nasal therapy (HFNT), extracorporeal membrane oxygenation (ECMO) and mortality. We identified and assessed 314 eligible articles from more than 40 countries, with 152 of these studies presenting mortality, 66 progression to severe or critical illness, 35 mortality and ICU admission combined, 17 ICU admission only, while the remaining 44 studies reported prediction models for mechanical ventilation (MV) or a combination of multiple outcomes. The sample size of included studies varied from 11 to 7,704,171 participants, with a mean age ranging from 18 to 93 years. There were 353 prognostic models investigated, with area under the curve (AUC) ranging from 0.44 to 0.99. A great proportion of studies (61.5%, 193 out of 314) performed internal or external validation or replication. In 312 (99.4%) studies, prognostic models were reported to be at high risk of bias due to uncertainties and challenges surrounding methodological rigor, sampling, handling of missing data, failure to deal with overfitting and heterogeneous definitions of COVID-19 and severity outcomes. While several clinical prognostic models for COVID-19 have been described in the literature, they are limited in generalizability and/or applicability due to deficiencies in addressing fundamental statistical and methodological concerns. Future large, multi-centric and well-designed prognostic prospective studies are needed to clarify remaining uncertainties.
MeSH term(s)	Adult ; Humans ; Adolescent ; Young Adult ; Middle Aged ; Aged ; Aged, 80 and over ; COVID-19 ; Prognosis ; Critical Care ; Intensive Care Units ; Hospitalization
Language	English
Publishing date	2023-02-25
Publishing country	Netherlands
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	632614-6
ISSN	1573-7284 ; 0393-2990
ISSN (online)	1573-7284
ISSN	0393-2990
DOI	10.1007/s10654-023-00973-x
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Article: Dietary Factors and Modulation of Bacteria Strains of <i>Akkermansia muciniphila</i> and <i>Faecalibacterium prausnitzii</i>: A Systematic Review

Verhoog, Sanne / Taneri, Petek Eylul / Roa Díaz, Zayne M / Marques-Vidal, Pedro / Troup, John P / Bally, Lia / Franco, Oscar H / Glisic, Marija / Muka, Taulant

Nutrients. 2019 July 11, v. 11, no. 7

2019

Abstract: Akkermansia muciniphila and Faecalibacterium prausnitzii are highly abundant human gut microbes in healthy individuals, and reduced levels are associated with inflammation and alterations of metabolic processes involved in the development of type 2 ... ...

Abstract	Akkermansia muciniphila and Faecalibacterium prausnitzii are highly abundant human gut microbes in healthy individuals, and reduced levels are associated with inflammation and alterations of metabolic processes involved in the development of type 2 diabetes. Dietary factors can influence the abundance of A. muciniphila and F. prausnitzii, but the evidence is not clear. We systematically searched PubMed and Embase to identify clinical trials investigating any dietary intervention in relation to A. muciniphila and F. prausnitzii. Overall, 29 unique trials were included, of which five examined A. muciniphila, 19 examined F. prausnitzii, and six examined both, in a total of 1444 participants. A caloric restriction diet and supplementation with pomegranate extract, resveratrol, polydextrose, yeast fermentate, sodium butyrate, and inulin increased the abundance of A. muciniphila, while a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols decreased the abundance of A. muciniphila. For F. prausnitzii, the main studied intervention was prebiotics (e.g. fructo-oligosaccharides, inulin type fructans, raffinose); seven studies reported an increase after prebiotic intervention, while two studies reported a decrease, and four studies reported no difference. Current evidence suggests that some dietary factors may influence the abundance of A. muciniphila and F. prausnitzii. However, more research is needed to support these microflora strains as targets of microbiome shifts with dietary intervention and their use as medical nutrition therapy in prevention and management of chronic disease.
Keywords	bacteria ; chronic diseases ; clinical trials ; disaccharides ; fructooligosaccharides ; fruit extracts ; humans ; inflammation ; intestinal microorganisms ; inulin ; low calorie diet ; microbiome ; monosaccharides ; noninsulin-dependent diabetes mellitus ; nutritional intervention ; polyols ; pomegranates ; prebiotics ; raffinose ; resveratrol ; sodium butyrate ; systematic review ; yeasts
Language	English
Dates of publication	2019-0711
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu11071565
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Dietary Factors and Modulation of Bacteria Strains of

Verhoog, Sanne / Taneri, Petek Eylul / Roa Díaz, Zayne M / Marques-Vidal, Pedro / Troup, John P / Bally, Lia / Franco, Oscar H / Glisic, Marija / Muka, Taulant

Nutrients

2019 Volume 11, Issue 7

Abstract: Akkermansia ... ...

Abstract	Akkermansia muciniphila
MeSH term(s)	Diet ; Faecalibacterium prausnitzii/drug effects ; Gastrointestinal Microbiome ; Humans ; Verrucomicrobia/drug effects
Language	English
Publishing date	2019-07-11
Publishing country	Switzerland
Document type	Journal Article ; Systematic Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu11071565
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Article ; Online: Anemia and iron metabolism in COVID-19: a systematic review and meta-analysis.

Taneri, Petek Eylul / Gómez-Ochoa, Sergio Alejandro / Llanaj, Erand / Raguindin, Peter Francis / Rojas, Lyda Z / Roa-Díaz, Zayne Milena / Salvador, Dante / Groothof, Dion / Minder, Beatrice / Kopp-Heim, Doris / Hautz, Wolf E / Eisenga, Michele F / Franco, Oscar H / Glisic, Marija / Muka, Taulant

European journal of epidemiology

2020 Volume 35, Issue 8, Page(s) 763–773

Abstract: Iron metabolism and anemia may play an important role in multiple organ dysfunction syndrome in Coronavirus disease 2019 (COVID-19). We conducted a systematic review and meta-analysis to evaluate biomarkers of anemia and iron metabolism (hemoglobin, ... ...

Abstract	Iron metabolism and anemia may play an important role in multiple organ dysfunction syndrome in Coronavirus disease 2019 (COVID-19). We conducted a systematic review and meta-analysis to evaluate biomarkers of anemia and iron metabolism (hemoglobin, ferritin, transferrin, soluble transferrin receptor, hepcidin, haptoglobin, unsaturated iron-binding capacity, erythropoietin, free erythrocyte protoporphyrine, and erythrocyte indices) in patients diagnosed with COVID-19, and explored their prognostic value. Six bibliographic databases were searched up to August 3rd 2020. We included 189 unique studies, with data from 57,563 COVID-19 patients. Pooled mean hemoglobin and ferritin levels in COVID-19 patients across all ages were 129.7 g/L (95% Confidence Interval (CI), 128.51; 130.88) and 777.33 ng/mL (95% CI, 701.33; 852.77), respectively. Hemoglobin levels were lower with older age, higher percentage of subjects with diabetes, hypertension and overall comorbidities, and admitted to intensive care. Ferritin level increased with older age, increasing proportion of hypertensive study participants, and increasing proportion of mortality. Compared to moderate cases, severe COVID-19 cases had lower hemoglobin [weighted mean difference (WMD), - 4.08 g/L (95% CI - 5.12; - 3.05)] and red blood cell count [WMD, - 0.16 × 10
MeSH term(s)	Anemia/diagnosis ; Betacoronavirus ; Biomarkers/analysis ; Biomarkers/blood ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus/metabolism ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Erythropoietin ; Ferritins/blood ; Hemoglobins/analysis ; Hemoglobins/metabolism ; Hepcidins/blood ; Hepcidins/metabolism ; Humans ; Iron/blood ; Iron/metabolism ; Pandemics ; Pneumonia, Viral/epidemiology ; Receptors, Transferrin/blood ; SARS-CoV-2 ; Transferrin/analysis ; Transferrin/metabolism
Chemical Substances	Biomarkers ; EPO protein, human ; HAMP protein, human ; Hemoglobins ; Hepcidins ; Receptors, Transferrin ; Transferrin ; Erythropoietin (11096-26-7) ; Ferritins (9007-73-2) ; Iron (E1UOL152H7)
Keywords	covid19
Language	English
Publishing date	2020-08-20
Publishing country	Netherlands
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	632614-6
ISSN	1573-7284 ; 0393-2990
ISSN (online)	1573-7284
ISSN	0393-2990
DOI	10.1007/s10654-020-00678-5
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