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  1. Book ; Online: Machine Learning and Embedded Computing in Advanced Driver Assistance Systems (ADAS)

    Ball, John / Tang, Bo

    2019  

    Abstract: This book contains the latest research on machine learning and embedded computing in advanced driver assistance systems (ADAS). It encompasses research in detection, tracking, ... ...

    Abstract This book contains the latest research on machine learning and embedded computing in advanced driver assistance systems (ADAS). It encompasses research in detection, tracking, LiDAR
    Keywords Technology (General) ; Engineering (General). Civil engineering (General)
    Size 1 electronic resource (344 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note eng ; Open Access
    HBZ-ID HT020323991
    ISBN 9783039213757 ; 9783039213764 ; 303921375X ; 3039213768
    DOI 10.3390/books978-3-03921-376-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Spatiotemporal change patterns and driving factors of land surface temperature in the Yunnan-Kweichow Plateau from 2000 to 2020.

    He, Zhi-Wei / Tang, Bo-Hui

    The Science of the total environment

    2023  Volume 896, Page(s) 165288

    Abstract: In this study, the spatiotemporal change patterns and driving factors of land surface temperature (LST) on the Yunnan-Kweichow Plateau (YKP) during 2000-2020 are investigated by using the Thermal and Reanalysis Integrating Moderate-resolution Spatial- ... ...

    Abstract In this study, the spatiotemporal change patterns and driving factors of land surface temperature (LST) on the Yunnan-Kweichow Plateau (YKP) during 2000-2020 are investigated by using the Thermal and Reanalysis Integrating Moderate-resolution Spatial-seamless (TRIMS) LST dataset provided by National Tibetan Plateau Data Center. The YKP LST spatiotemporal change patterns are revealed at annual, seasonal, monthly, and daily scales. Furthermore, seven driving factors such as air temperature, land cover types, normalized difference vegetation index, precipitation, solar radiation, elevation, and latitude are quantified the impacts on LST spatial heterogeneity at annual scale. The main findings are as follows: (1) Annual mean LST increases by 0.016 K/year. Annual mean daytime LST slightly decreases by 0.009 K/year. Annual mean nighttime LST significantly increases by 0.042 K/year. (2) The trend and seasonal components of the daily, daily mean daytime, and daily mean nighttime LST have five and four breakpoints respectively, indicating that the variation of LST is unstable during 2000-2020 on the YKP. (3) The LST lapse rates at nighttime are generally higher than those at daytime on the YKP at the annual, seasonal, and monthly scales. The LST maximum lapse rate is 0.59 K/100 m in summer nighttime, and the LST minimum lapse rate is 0.18 K/100 m in winter daytime. (4) The controlling effects of seven factors are generally stronger in the nighttime than those in the daytime. The factors of elevation and air temperature dominate the LST spatial distribution on the YKP, with a contribution rate of >70 %. In addition, the interactions among the seven factors are all enhancing the effects on the spatial distribution of annual mean LST, including bivariate enhancement and nonlinear enhancement. This study contributes to the mitigation and adaptation to climate change of LST in the plateau and plays a theoretical reference role in formulating corresponding policies for environmental protection.
    Language English
    Publishing date 2023-07-03
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.165288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A study on the spatial-temporal patterns and influencing factors of atmospheric vulnerability in the Pearl River Delta.

    Tang, Bo / Tan, Zhixiong

    PloS one

    2023  Volume 18, Issue 11, Page(s) e0289436

    Abstract: Atmospheric environmental assessment has emerged as a prominent area of research due to global climate change and regional atmospheric pollution issues. Accurate evaluation of atmospheric environmental vulnerability characteristics and understanding ... ...

    Abstract Atmospheric environmental assessment has emerged as a prominent area of research due to global climate change and regional atmospheric pollution issues. Accurate evaluation of atmospheric environmental vulnerability characteristics and understanding driving mechanisms are crucial for effective air pollution monitoring and prevention. This study focuses on the Pearl River Delta (PRD) region and employs the Vulnerability-Scoping-Diagram (VSD) model framework to establish an index system for assessing atmospheric environmental vulnerability based on exposure, sensitivity, and adaptability, combining the entropy value method and adopts Geographic Information System (GIS) for the time change and spatial evolution analysis, and finally utilizing the factor detection and interaction in Geodetector to explore the contribution degree of each driving factor of atmospheric environmental vulnerability and the exchange of influencing factors. The findings of this research are as follows: Firstly, the sensitivity index and resilience index of the atmospheric environment of the PRD exhibit an overall upward trend with fluctuations, while the exposure index demonstrates a pattern of initial increase, followed by a decrease, and subsequent increase with significant interannual variability. Secondly, the atmospheric environment vulnerability level of the PRD is primarily categorized as low and mild, with a negligible proportion of moderate vulnerability and no instances of severe or extreme vulnerability. The vulnerability index shows an initial increase followed by a subsequent decline from 2016 to 2020, indicating an overall improvement in the region's atmospheric environment. Thirdly, notable variations exist in the atmospheric environment vulnerability indices among the nine cities in the PRD, in which moderate vulnerability and low vulnerability are mainly concentrated in Guangzhou, Shenzhen, Foshan, and Dongguan in the central part of the PRD. lower vulnerability is primarily observed in the eastern and western regions of the PRD characterized by favorable natural environments and limited human interference, such as Huizhou, Zhaoqing, and Zhuhai. Finally, the atmospheric environment vulnerability of the PRD is the result of the combined effect of various driving factors, among which the urban built-up area, PM2.5 concentration, SO2 concentration, population density and the share of tertiary industry in GDP are the key drivers.
    MeSH term(s) Humans ; Environmental Monitoring/methods ; Rivers ; Air Pollution/analysis ; Geographic Information Systems ; Cities ; China ; Air Pollutants/analysis
    Chemical Substances Air Pollutants
    Language English
    Publishing date 2023-11-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0289436
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The chain mediating effect of shared leadership on team innovation.

    Tang, Bo / Han, Yang / He, Gang / Li, Xianmiao

    Heliyon

    2024  Volume 10, Issue 3, Page(s) e25282

    Abstract: Background: Although recent literature has explored the effectiveness of shared leadership in teamwork, there is still a lack of more in-depth research on the process mechanism of shared leadership's effect on team innovation.: Objective: Based on ... ...

    Abstract Background: Although recent literature has explored the effectiveness of shared leadership in teamwork, there is still a lack of more in-depth research on the process mechanism of shared leadership's effect on team innovation.
    Objective: Based on self-determination theory, social cognitive theory and adaptive structure theory, this study investigates the influence of shared leadership on team innovation, as well as the mediating roles played by team member exchange (TMX) and team resilience. A total of 107 knowledge-based teams were invited to participate in the study.
    Results: The findings indicate that: (1) shared leadership has a positive influence on team innovation, TMX and team resilience; (2) TMX and team resilience, respectively, mediate the influence of shared leadership on team innovation; (3) TMX and team resilience play a chain mediating role between shared leadership and team innovation.
    Conclusion: In knowledge-based teams, shared leadership has a positive effect on team innovation by promoting team communication and enhancing team resilience. The results contribute to research on the relationship between shared leadership and team innovation and their practical applications.
    Language English
    Publishing date 2024-01-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e25282
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The association between serum heat shock protein 72 and intestinal permeability with intestinal microbiota and clinical severity in patients with cerebral infarction.

    Zhu, Jiahui / Dai, Yijie / Tang, Bo / Zhang, Hao

    Frontiers in medicine

    2024  Volume 10, Page(s) 1302460

    Abstract: Objectives: We aimed to compare serum heat shock protein 72 (HSP72) and intestinal permeability in patients with cerebral infarction (CI) and healthy individuals to reveal their correlations and link to gut microbiota alterations and clinical severity ... ...

    Abstract Objectives: We aimed to compare serum heat shock protein 72 (HSP72) and intestinal permeability in patients with cerebral infarction (CI) and healthy individuals to reveal their correlations and link to gut microbiota alterations and clinical severity of CI.
    Methods and results: Stool samples of 50 patients with CI and 46 healthy volunteers were analyzed through 16S rRNA gene sequencing to characterize intestinal flora profiles. Serum HSP72 and zonulin were assayed using enzyme-linked immunoassay (ELISA). The obtained data were then subjected to comparative and correlative analysis. We found that the levels of zonulin and serum HSP72 were significantly higher in the CI group compared to the healthy group. Serum HSP72 and zonulin levels were positively correlated in the CI group and correlated positively with the clinical severity of CI. β diversity showed significant differences in intestinal microbiota composition between the two groups. In the CI patient group, the abundance of bacteria
    Conclusion: Our findings indicated that an increase in serum HSP72 and zonulin levels was manifested in patients with CI and was related to specific gut microbiota alterations and the clinical severity of CI.
    Language English
    Publishing date 2024-01-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1302460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Green Synthesis of CQDs via the Trunks of Bauhinia purpurea as Fluorescence Probes for Rapid and Accurate Detection of Quinoline Yellow.

    Ge, Ziyang / Du, Haiying / Tang, Bo / Deng, Jie

    Journal of fluorescence

    2024  

    Abstract: Carbon quantum dots (CQDs) were greenly synthesized via a single-step hydrothermal method, using the trunks of Bauhinia purpurea as the carbon source. They exhibited good dispersibility, water solubility, high sensitivity, and great stability with a ... ...

    Abstract Carbon quantum dots (CQDs) were greenly synthesized via a single-step hydrothermal method, using the trunks of Bauhinia purpurea as the carbon source. They exhibited good dispersibility, water solubility, high sensitivity, and great stability with a spherical form and a particle size of 2.68 ± 0.32 nm. By utilizing the inner filter effect and dynamic quenching effect, the fluorescence quenching of CQDs can be induced to detect quinoline yellow. Detailed experimental results showed that the change rate of fluorescence intensity of CQDs had a good linear relationship with varying concentrations of quinoline yellow (2-128 µmol/L). It can be clearly observed that the fluorescence quenching occurred within 1 min, its correlation coefficient (R
    Language English
    Publishing date 2024-05-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2016892-5
    ISSN 1573-4994 ; 1053-0509
    ISSN (online) 1573-4994
    ISSN 1053-0509
    DOI 10.1007/s10895-024-03699-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: STK11 (LKB1) mutation suppresses ferroptosis in lung adenocarcinoma by facilitating monounsaturated fatty acid synthesis

    Zou Qiang / Tang Bo / Chen Xianchao / Zhang Chuang / Huang Yun

    Open Medicine, Vol 19, Iss 1, Pp 209-

    2024  Volume 49

    Abstract: Serine/threonine kinase 11 (STK11), a tumor suppressor gene, exhibits frequent mutations in lung adenocarcinoma (LUAD). However, the specific molecular mechanisms by which STK11 mutations exert an influence on the biosynthesis of monounsaturated fatty ... ...

    Abstract Serine/threonine kinase 11 (STK11), a tumor suppressor gene, exhibits frequent mutations in lung adenocarcinoma (LUAD). However, the specific molecular mechanisms by which STK11 mutations exert an influence on the biosynthesis of monounsaturated fatty acids (MUFAs) and subsequently affect ferroptosis in LUAD remain indistinct. In this study, bioinformatic analysis was employed to probe into the linkage between STK11 and key inhibitory genes of ferroptosis, namely SLC7A11 and SCD1, in LUAD tissues. Quantitative reverse transcription polymerase chain reaction was employed to assess the expression of STK11 in both wild-type and mutant STK11 LUAD cells, cell counting kit-8 to assess cell viability, and flow cytometry to detect apoptosis. A transmission electron microscope was utilized to observe mitochondrial morphology, and Western blot to ascertain the protein expression of STK11, ferroptosis-related proteins, and the enzyme SCD1 involved in MUFA synthesis. Oil red O staining was employed to test the distribution of lipid droplets in cancer cells, and a lipid quantification method to measure the content of MUFAs. Commercial kits were employed to assess the levels of lipid reactive oxygen species, malondialdehyde, glutathione, and Fe2+ in cells. The result revealed a negative correlation between STK11 and SLC7A11 as well as SCD1, with STK11 expression downregulated in mutant STK11 LUAD cells. Furthermore, STK11 mutations were found to suppress ferroptosis in LUAD cells by affecting MUFA synthesis. Subsequent rescue assays demonstrated that STK11 mutations hindered ferroptosis by impacting the synthesis of MUFAs in LUAD cells. This study provided evidence that STK11 mutations suppressed ferroptosis in LUAD cells by promoting MUFA synthesis, thus offering a novel research direction in the management of LUAD.
    Keywords stk11 ; lung adenocarcinoma ; monounsaturated fatty acid synthesis ; ferroptosis ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher De Gruyter
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Mechanisms of Reactions between HOI and HY (Y = Cl, Br, I) on a Water Nanodroplet Surface.

    Tang, Bo / Li, Zhenyu

    The journal of physical chemistry. A

    2022  Volume 126, Issue 43, Page(s) 8028–8036

    Abstract: Iodine chemistry has a broad range of implications for atmospheric processes including new particle formation. Hypoiodous acid (HOI) is a major iodine reservoir species. Its heterogeneous recycling in marine aerosols influences the lifetime of ozone in ... ...

    Abstract Iodine chemistry has a broad range of implications for atmospheric processes including new particle formation. Hypoiodous acid (HOI) is a major iodine reservoir species. Its heterogeneous recycling in marine aerosols influences the lifetime of ozone in the troposphere. One important step of such recycling is the reaction between HOI and HY (Y = Cl, Br, I). In this article, we employ
    Language English
    Publishing date 2022-10-19
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5215
    ISSN (online) 1520-5215
    DOI 10.1021/acs.jpca.2c05414
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: STK11 (LKB1) mutation suppresses ferroptosis in lung adenocarcinoma by facilitating monounsaturated fatty acid synthesis.

    Zou, Qiang / Tang, Bo / Chen, Xianchao / Zhang, Chuang / Huang, Yun

    Open medicine (Warsaw, Poland)

    2024  Volume 19, Issue 1, Page(s) 20230845

    Abstract: Serine/threonine kinase 11 (STK11), a tumor suppressor gene, exhibits frequent mutations in lung adenocarcinoma (LUAD). However, the specific molecular mechanisms by which STK11 mutations exert an influence on the biosynthesis of monounsaturated fatty ... ...

    Abstract Serine/threonine kinase 11 (STK11), a tumor suppressor gene, exhibits frequent mutations in lung adenocarcinoma (LUAD). However, the specific molecular mechanisms by which STK11 mutations exert an influence on the biosynthesis of monounsaturated fatty acids (MUFAs) and subsequently affect ferroptosis in LUAD remain indistinct. In this study, bioinformatic analysis was employed to probe into the linkage between STK11 and key inhibitory genes of ferroptosis, namely SLC7A11 and SCD1, in LUAD tissues. Quantitative reverse transcription polymerase chain reaction was employed to assess the expression of STK11 in both wild-type and mutant STK11 LUAD cells, cell counting kit-8 to assess cell viability, and flow cytometry to detect apoptosis. A transmission electron microscope was utilized to observe mitochondrial morphology, and Western blot to ascertain the protein expression of STK11, ferroptosis-related proteins, and the enzyme SCD1 involved in MUFA synthesis. Oil red O staining was employed to test the distribution of lipid droplets in cancer cells, and a lipid quantification method to measure the content of MUFAs. Commercial kits were employed to assess the levels of lipid reactive oxygen species, malondialdehyde, glutathione, and Fe
    Language English
    Publishing date 2024-01-06
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2829380-0
    ISSN 2391-5463
    ISSN 2391-5463
    DOI 10.1515/med-2023-0845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Relationship between inflammatory bowel disease and erectile dysfunction: a 2-sample Mendelian randomization study.

    Gao, Dawei / Chen, Cheng / Wu, Ziliang / Li, Huakang / Tang, Bo

    Sexual medicine

    2024  Volume 11, Issue 6, Page(s) qfad067

    Abstract: Background: Observational studies have indicated a high prevalence of erectile dysfunction (ED) among patients with inflammatory bowel disease (IBD), but a definitive causal relationship remains unestablished.: Aim: The primary aim of this study was ... ...

    Abstract Background: Observational studies have indicated a high prevalence of erectile dysfunction (ED) among patients with inflammatory bowel disease (IBD), but a definitive causal relationship remains unestablished.
    Aim: The primary aim of this study was to assess the potential causal relationship between IBD and ED using Mendelian randomization (MR) analysis.
    Methods: We obtained statistical data for 2 subtypes of IBD, ulcerative colitis (UC) and Crohn's disease (CD), as well as for ED, from publicly available genome-wide association studies (GWASs). Subsequently, a 2-sample MR analysis was conducted using these datasets. The primary MR analysis utilized the inverse variance-weighted (IVW) method, complemented by secondary analyses employing MR-Egger and weighted median methods. Furthermore, we assessed heterogeneity using Cochran's Q test and evaluated pleiotropy with the MR-Egger intercept test. To identify potential influential single nucleotide polymorphisms, we employed a leave-one-out analysis. Additionally, outliers were identified using the MR-PRESSO method.
    Outcomes: The study outcomes encompassed results from 3 MR analyses, namely IVW, MR-Egger, and weighted median, along with sensitivity analyses involving Cochran's Q test, the MR-Egger intercept test, leave-one-out analysis, and the MR-PRESSO method.
    Results: There was no causal effect of UC and CD on ED in the MR analysis (IVW
    Clinical implications: Genetically, despite the absence of a causal link between IBD and ED according to MR analysis, we must emphasize the elevated ED prevalence among IBD patients in observational studies, with particular consideration for the influence of negative emotions on erectile function.
    Strengths & limitations: This study is the inaugural application of a 2-sample MR analysis using extensive GWAS datasets to evaluate the causal relationship between IBD and ED, effectively mitigating biases stemming from confounding factors and reverse causality often present in observational studies. Nevertheless, it is imperative to exercise caution when drawing conclusions due to inherent limitations in GWAS data, encompassing factors like samples overlap, gender categorization, population ancestry, and the persistent ambiguity surrounding the precise functionality of specific single nucleotide polymorphisms.
    Conclusions: MR analysis did not provide genetic-level evidence supporting a direct causal relationship between IBD (UC and CD) and ED.
    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2734882-9
    ISSN 2050-1161
    ISSN 2050-1161
    DOI 10.1093/sexmed/qfad067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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