LIVIVO - Search results -

Search results

Result 1 - 10 of total 97

Search options

Article ; Online: A Review of the Use of Native and Engineered Probiotics for Colorectal Cancer Therapy.

Han, Huawen / Zhang, Yifan / Tang, Haibo / Zhou, Tuoyu / Khan, Aman

International journal of molecular sciences

2024 Volume 25, Issue 7

Abstract: Colorectal cancer (CRC) is a serious global health concern, and researchers have been investigating different strategies to prevent, treat, or support conventional therapies for CRC. This review article comprehensively covers CRC therapy involving wild- ... ...

Abstract	Colorectal cancer (CRC) is a serious global health concern, and researchers have been investigating different strategies to prevent, treat, or support conventional therapies for CRC. This review article comprehensively covers CRC therapy involving wild-type bacteria, including probiotics and oncolytic bacteria as well as genetically modified bacteria. Given the close relationship between CRC and the gut microbiota, it is crucial to compile and present a comprehensive overview of bacterial therapies used in the context of colorectal cancer. It is evident that the use of native and engineered probiotics for colorectal cancer therapy necessitates research focused on enhancing the therapeutic properties of probiotic strains.. Genetically engineered probiotics might be designed to produce particular molecules or to target cancer cells more effectively and cure CRC patients.
MeSH term(s)	Humans ; Gastrointestinal Microbiome ; Genetic Engineering ; Probiotics/therapeutic use ; Research Personnel ; Colorectal Neoplasms/therapy
Language	English
Publishing date	2024-03-31
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms25073896
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Exploring the impact of preoperative insulin resistance levels on outcomes after metabolic surgery: a focus on multiracial type 2 diabetes patients.

Cao, Yaoquan / Tang, Haibo / Zhu, Shaihong / Zhu, Liyong

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

2023 Volume 20, Issue 2, Page(s) 214

MeSH term(s)	Humans ; Insulin Resistance ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/surgery ; Diabetes Mellitus, Type 2/metabolism ; Bariatric Surgery ; Blood Glucose/metabolism ; Insulin/metabolism
Chemical Substances	Blood Glucose ; Insulin
Language	English
Publishing date	2023-11-02
Publishing country	United States
Document type	Letter
ZDB-ID	2274243-8
ISSN	1878-7533 ; 1550-7289
ISSN (online)	1878-7533
ISSN	1550-7289
DOI	10.1016/j.soard.2023.10.007
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 6572: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Why more successful? An analysis of participants' self-monitoring data in an online weight loss intervention.

Tang, Hai-Bo / Jalil, Nurul Iman Binti Abdul / Tan, Chee-Seng / He, Ling / Zhang, Shu-Juan

BMC public health

2024 Volume 24, Issue 1, Page(s) 322

Abstract: Background: Self-monitoring is crucial for behavioral weight loss. However, few studies have examined the role of self-monitoring using mixed methods, which may hinder our understanding of its impact.: Methods: This study examined self-monitoring ... ...

Abstract	Background: Self-monitoring is crucial for behavioral weight loss. However, few studies have examined the role of self-monitoring using mixed methods, which may hinder our understanding of its impact. Methods: This study examined self-monitoring data from 61 Chinese adults who participated in a 5-week online group intervention for weight loss. Participants reported their baseline Body Mass Index (BMI), weight loss motivation, and engaged in both daily quantitative self-monitoring (e.g., caloric intake, mood, sedentary behavior, etc.) and qualitative self-monitoring (e.g., daily log that summarizes the progress of weight loss). The timeliness of participants' daily self-monitoring data filling was assessed using a scoring rule. One-way repeated measurement ANOVA was employed to analyze the dynamics of each self-monitoring indicator. Correlation and regression analyses were used to reveal the relationship between baseline data, self-monitoring indicators, and weight change. Content analysis was utilized to analyze participants' qualitative self-monitoring data. Participants were categorized into three groups based on their weight loss outcomes, and a chi-square test was used to compare the frequency distribution between these groups. Results: After the intervention, participants achieved an average weight loss of 2.52 kg (SD = 1.36) and 3.99% (SD = 1.96%) of their initial weight. Daily caloric intake, weight loss satisfaction, frequency of daily log, and the speed of weight loss showed a downward trend, but daily sedentary time gradually increased. Moreover, regression analysis showed that baseline BMI, weight loss motivation, and timeliness of daily filling predicted final weight loss. Qualitative self-monitoring data analysis revealed four categories and nineteen subcategories. A significant difference in the frequency of qualitative data was observed, with the excellent group reporting a greater number of daily logs than expected in all categories and most subcategories, and the moderate and poor groups reporting less than expected in all categories and most subcategories. Conclusion: The self-monitoring data in short-term online group intervention exhibited fluctuations. Participants with higher baseline BMI, higher levels of weight loss motivation, and timely self-monitoring achieved more weight loss. Participants who achieved greater weight loss reported a higher quantity of qualitative self-monitoring data. Practitioners should focus on enhancing dieters' weight loss motivation and promote adherence to self-monitoring practices.
MeSH term(s)	Adult ; Humans ; Weight Loss ; Body Mass Index ; Health Behavior ; Behavior Therapy/methods ; Energy Intake
Language	English
Publishing date	2024-01-29
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-024-17848-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The miR-3074/BMP7 axis regulates TGF-β-caused activation of hepatic stellate cells in vitro and CCl

Liu, Bingjie / Xie, Xia / Yang, Xin / Dou, Chengyun / Tang, Haibo / Liu, Jing

Human cell

2024 Volume 37, Issue 2, Page(s) 435–450

Abstract: Continuously progressive hepatic fibrosis might cause chronic liver diseases, resulting in hepatic failure. The activation of hepatic stellate cells (HSCs) residing in the liver might induce and influence hepatic fibrosis. In the present study, microRNA ... ...

Abstract	Continuously progressive hepatic fibrosis might cause chronic liver diseases, resulting in hepatic failure. The activation of hepatic stellate cells (HSCs) residing in the liver might induce and influence hepatic fibrosis. In the present study, microRNA 3074 (miR-3074) was found increased within transforming growth factor-β (TGF-β)-activated HSCs and enriched within the TGF-β signaling. In activated HSCs by TGF-β, miR-3074 overexpression aggravated TGF-β-induced fibrotic changes, whereas miR-3074 inhibition exerted opposite effects. miR-3074 directly targeted bone morphogenetic protein 7 (BMP7) and inhibited BMP7 expression. Under TGF-β induction, overexpressed BMP7 notably attenuated the promotive roles of miR-3074 overexpression in TGF-β-activated HSCs. Within carbon tetrachloride (CCl
MeSH term(s)	Animals ; Mice ; Bone Morphogenetic Protein 7/genetics ; Bone Morphogenetic Protein 7/adverse effects ; Bone Morphogenetic Protein 7/metabolism ; Hepatic Stellate Cells/pathology ; Liver/metabolism ; Liver Cirrhosis/genetics ; Liver Cirrhosis/chemically induced ; MicroRNAs/metabolism ; Transforming Growth Factor beta/metabolism ; Transforming Growth Factor beta1/metabolism
Chemical Substances	Bone Morphogenetic Protein 7 ; MicroRNAs ; Transforming Growth Factor beta ; Transforming Growth Factor beta1 ; bmp7 protein, mouse
Language	English
Publishing date	2024-01-14
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1149134-6
ISSN	1749-0774 ; 0914-7470
ISSN (online)	1749-0774
ISSN	0914-7470
DOI	10.1007/s13577-023-01017-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 3676: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Real-time evolution of oil shale meso-structure under triaxial stress condition

Tang Haibo / Kang Zhiqin / Wang Kun

E3S Web of Conferences, Vol 248, p

2021 Volume 01049

Abstract: It is significant to research the mechanical properties and micro-fracture evolution characteristics of oil shales with different bedding directions under the condition of in-situ triaxial stress loading for understanding the internal micro- ... ...

Abstract	It is significant to research the mechanical properties and micro-fracture evolution characteristics of oil shales with different bedding directions under the condition of in-situ triaxial stress loading for understanding the internal micro-characteristics of oil shales. Triaxial stress loading tests of cylindrical oil shales were carried out in two loading directions perpendicular to and parallel to the bedding, which is the S1 and S2 samples. Our results demonstrate that the oil shales are typical anisotropic and brittle fracture characteristics. The triaxial compressive strength of S1 is higher than that of S2, but the elastic modulus is almost the same. Based on the reconstructed 3D-CT image, we analyzed the dynamic evolution law of the fracture inside the sample in the horizontal and vertical directions, and obtained the distribution of the fracture in the loading process, finally revealing the internal micro-characteristics of oil shales under the different loading conditions.
Keywords	Environmental sciences ; GE1-350
Subject code	621
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Efficacy and Safety of Convalescence Plasma Therapy in COVID-19 Patients: A Systematic Review and Meta-Analysis.

Dai, Rongjuan / Hu, Minjie / Tang, Haibo / Peng, Zhongtian / Yan, Cai

Evidence-based complementary and alternative medicine : eCAM

2022 Volume 2022, Page(s) 7670817

Abstract: Background: The coronavirus disease 2019 (COVID-19) has outbroken into a global pandemic. The death rate for hospital patients varied between 11% and 15%. Although COVID-19 is extremely contagious and has a high fatality rate, the amount of knowledge ... ...

Abstract	Background: The coronavirus disease 2019 (COVID-19) has outbroken into a global pandemic. The death rate for hospital patients varied between 11% and 15%. Although COVID-19 is extremely contagious and has a high fatality rate, the amount of knowledge available in the published literature and public sources is rapidly growing. The efficacy of convalescent plasma (CP) therapy for COVID-19 is controversial. Objective: This meta-analysis was designed to assess the efficacy of CP therapy for COVID-19 through a literature survey. Methods: Until August 30, 2021, a literature search was undertaken in Pubmed, Embase, Web of Science, Cochrane Central Register of Controlling Trials (Central), and China National Knowledge Infrastructure databases. The Risk Ratio (RR) and 95% confidence intervals (CIs) were pooled using a fixed or random effect model in dichotomous data. Mean difference (MD) and 95% confidence intervals (CIs) were pooled using a fixed or random effect model in continuous data. Studies with missing or unsuitable data were presented descriptively in the outcomes. Results: In total, thirteen randomized controlled trials (RCTs) were selected for the present meta-analysis, which included a total of 13232 participants. Our results revealed that the CP group has lower mortality compared to the control group, and there was a statistically significant difference (RR: 0.70, 95% CI: 0.55, 0.89, Conclusions: The safety and potential efficacy of convalescent plasma therapy offer a promising treatment strategy for COVID-19. CP therapy can reduce mortality and improve breath and inflammatory cytokines IL-6 and Ferritin in COVID-19 with no significant increase in adverse reactions. However, it does not affect improving virology indicators. In summary, more high-quality clinical trials are needed to verify the conclusion of the present study.
Language	English
Publishing date	2022-10-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2022/7670817
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5995: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Age at Menarche Mediating Visceral Adipose Tissue's Influence on Pre-eclampsia: A Mendelian Randomization Study.

Deng, Peizhi / Yu, Qingwei / Tang, Haibo / Lu, Yao / He, Yingdong

The Journal of clinical endocrinology and metabolism

2022 Volume 108, Issue 2, Page(s) 405–413

Abstract: Context: The association between visceral adipose tissue (VAT) and pre-eclampsia (PE) shows inconsistent results and the underlying mediator remains unknown.: Objective: We aimed to explore the causal effect of VAT on PE risks and the mediation role ... ...

Abstract	Context: The association between visceral adipose tissue (VAT) and pre-eclampsia (PE) shows inconsistent results and the underlying mediator remains unknown. Objective: We aimed to explore the causal effect of VAT on PE risks and the mediation role of age at menarche (AAM) in explaining this relationship. Methods: Summary data for PE were obtained from the FinnGen genome-wide association study (3556 cases and 114 735 controls). For exposure data, 70 genetic variants associated with the predicted VAT in 161 149 European women from UK Biobank were used as instrumental variables. Inverse variance weighted and multiple sensitivity analyses were applied. We also conducted multivariable Mendelian randomization (MR) analyses to test the association between VAT-associated single-nucleotide variations and PE. Next, mediation analyses were performed to study whether the association between VAT and PE was mediated via AAM. Results: In univariable MR analysis, higher volume of VAT was associated with the advancement of AAM and increased PE risk (beta = -0.33; 95% CI, -0.49 to -0.16 for AAM; odds ratio 1.65, 95% CI, 1.23 to 2.20 for PE). After adjusting for waist circumference, waist to hip ratio, and hip circumference, the multivariable MR results presented the consistent positive causality of VAT on PE. Two-step MR analysis proved an estimated 14.3% of the positive effect of VAT on PE was mediated by AAM. Conclusion: Our findings provided evidence of the causal relationship between VAT and PE and proved VAT could accelerate AAM and then contribute to the risk of incident PE.
MeSH term(s)	Pregnancy ; Humans ; Female ; Menarche/genetics ; Pre-Eclampsia/epidemiology ; Pre-Eclampsia/genetics ; Mendelian Randomization Analysis ; Genome-Wide Association Study ; Intra-Abdominal Fat ; Body Mass Index ; Obesity, Abdominal ; Polymorphism, Single Nucleotide
Language	English
Publishing date	2022-09-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3029-6
ISSN	1945-7197 ; 0021-972X
ISSN (online)	1945-7197
ISSN	0021-972X
DOI	10.1210/clinem/dgac566
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh III Zs.134: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Mechanism of RNA circHIPK3 Involved in Resistance of Lung Cancer Cells to Gefitinib.

Zhao, Yi / Zhang, Caiming / Tang, Haibo / Wu, Xiaomin / Qi, Qiugan

publication RETRACTED

BioMed research international

2022 Volume 2022, Page(s) 4541918

Abstract: To study the mechanism of circular ribonucleic acid (RNA) circHIPK3 involved in the resistance of lung cancer cells to gefitinib, 110 patients with lung cancer were recruited as the research objects, and the tumor tissue and para-cancerous tissue of each ...

Abstract	To study the mechanism of circular ribonucleic acid (RNA) circHIPK3 involved in the resistance of lung cancer cells to gefitinib, 110 patients with lung cancer were recruited as the research objects, and the tumor tissue and para-cancerous tissue of each patient's surgical specimens were collected and paraffinized to detect the expression of circHIPK3 in different tissues. Gefitinib drug-resistant cell line of lung cancer was constructed with gefitinib to detect cell apoptosis under different conditions. As a result, the relative expression of circHIPK3 in patients with tumor diameter no less than 3 cm was dramatically inferior to that in patients with tumor diameter less than 3 cm (
MeSH term(s)	Cell Line, Tumor ; Cell Proliferation/genetics ; Gefitinib/pharmacology ; Humans ; Lung/metabolism ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Lymphatic Metastasis ; MicroRNAs/genetics ; RNA, Circular/genetics
Chemical Substances	MicroRNAs ; RNA, Circular ; Gefitinib (S65743JHBS)
Language	English
Publishing date	2022-04-19
Publishing country	United States
Document type	Journal Article ; Retracted Publication
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2022/4541918
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Smoking, DNA Methylation, and Breast Cancer: A Mendelian Randomization Study.

Tang, Haibo / Yang, Desong / Han, Chaofei / Mu, Ping

Frontiers in oncology

2021 Volume 11, Page(s) 745918

Abstract: Background: Smoking was strongly associated with breast cancer in previous studies. Whether smoking promotes breast cancer through DNA methylation remains unknown.: Methods: Two-sample Mendelian randomization (MR) analyses were conducted to assess ... ...

Abstract	Background: Smoking was strongly associated with breast cancer in previous studies. Whether smoking promotes breast cancer through DNA methylation remains unknown. Methods: Two-sample Mendelian randomization (MR) analyses were conducted to assess the causal effect of smoking-related DNA methylation on breast cancer risk. We used 436 smoking-related CpG sites extracted from 846 middle-aged women in the ARIES project as exposure data. We collected summary data of breast cancer from one of the largest meta-analyses, including 69,501 cases for ER+ breast cancer and 21,468 cases for ER- breast cancer. A total of 485 single-nucleotide polymorphisms (SNPs) were selected as instrumental variables (IVs) for smoking-related DNA methylation. We further performed an MR Steiger test to estimate the likely direction of causal estimate between DNA methylation and breast cancer. We also conducted colocalization analysis to evaluate whether smoking-related CpG sites shared a common genetic causal SNP with breast cancer in a given region. Results: We established four significant associations after multiple testing correction: the CpG sites of cg2583948 [OR = 0.94, 95% CI (0.91-0.97)], cg0760265 [OR = 1.07, 95% CI (1.03-1.11)], cg0420946 [OR = 0.95, 95% CI (0.93-0.98)], and cg2037583 [OR =1.09, 95% CI (1.04-1.15)] were associated with the risk of ER+ breast cancer. All the four smoking-related CpG sites had a larger variance than that in ER+ breast cancer (all Conclusions: These findings highlight potential targets for the prevention of ER+ breast cancer. Tissue-specific epigenetic data are required to confirm these results.
Language	English
Publishing date	2021-09-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2021.745918
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Temporal Relationship Between Insulin Resistance and Lipid Accumulation After Bariatric Surgery: a Multicenter Cohort Study.

Tang, Haibo / Ling, Jiapu / Meng, Hua / Wu, Liangping / Zhu, Liyong / Zhu, Shaihong

Obesity surgery

2023 Volume 33, Issue 6, Page(s) 1720–1729

Abstract: Purpose: Insulin resistance (IR) is closely associated with lipid accumulation. Here, we investigated the temporal relationship between the two conditions after bariatric surgery.: Materials and methods: In total, 409 participants were enrolled from ... ...

Abstract	Purpose: Insulin resistance (IR) is closely associated with lipid accumulation. Here, we investigated the temporal relationship between the two conditions after bariatric surgery. Materials and methods: In total, 409 participants were enrolled from three bariatric centers in China from 2009 to 2018. We evaluated whether baseline IR (proxied by homeostasis model assessment of insulin resistance (HOMA-IR)) and lipid accumulation (proxied by visceral adiposity index (VAI) and lipid accumulation product (LAP)) were associated with follow-up IR and lipid accumulation (3 months postoperatively) using linear regression models. We then conducted a cross-lagged panel analysis model to simultaneously examine the bidirectional relationship between IR and lipid accumulation. Results: Multivariable linear regression analyses showed that baseline HOMA-IR was associated with follow-up VAI (β = 0.430, 95% CI: 0.082-0.778, p = 0.016) and LAP (β = 0.070, 95% CI: 0.010-0.130, p = 0.022). There was no relationship between baseline lipid accumulation and follow-up IR. Further cross-lagged panel analyses indicated that the path coefficient from baseline HOMA-IR to follow-up VAI (β Conclusion: Our study demonstrated a unidirectional relationship from HOMA-IR to VAI and LAP, suggesting that the change in IR may precede lipid accumulation after surgery.
MeSH term(s)	Humans ; Insulin Resistance ; Obesity, Morbid/surgery ; Lipids ; Bariatric Surgery ; Cohort Studies ; Adiposity ; Body Mass Index
Chemical Substances	Lipids
Language	English
Publishing date	2023-04-15
Publishing country	United States
Document type	Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-023-06508-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 3381: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito