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  1. Article ; Online: Exploration of neuron heterogeneity in human heart failure with dilated cardiomyopathy through single-cell RNA sequencing analysis.

    Cui, Yu-Hui / Wu, Chun-Rong / Xu, Dan / Tang, Jian-Guo

    BMC cardiovascular disorders

    2024  Volume 24, Issue 1, Page(s) 86

    Abstract: Objective: We aimed to explore the heterogeneity of neurons in heart failure with dilated cardiomyopathy (DCM).: Methods: Single-cell RNA sequencing (scRNA-seq) data of patients with DCM and chronic heart failure and healthy samples from GSE183852 ... ...

    Abstract Objective: We aimed to explore the heterogeneity of neurons in heart failure with dilated cardiomyopathy (DCM).
    Methods: Single-cell RNA sequencing (scRNA-seq) data of patients with DCM and chronic heart failure and healthy samples from GSE183852 dataset were downloaded from NCBI Gene Expression Omnibus, in which neuron data were extracted for investigation. Cell clustering analysis, differential expression analysis, trajectory analysis, and cell communication analysis were performed, and highly expressed genes in neurons from patients were used to construct a protein-protein interaction (PPI) network and validated by GSE120895 dataset.
    Results: Neurons were divided into six subclusters involved in various biological processes and each subcluster owned its specific cell communication pathways. Neurons were differentiated into two branches along the pseudotime, one of which was differentiated into mature neurons, whereas another tended to be involved in the immune and inflammation response. Genes exhibited branch-specific differential expression patterns. FLNA, ITGA6, ITGA1, and MDK interacted more with other gene-product proteins in the PPI network. The differential expression of FLNA between DCM and control was validated.
    Conclusion: Neurons have significant heterogeneity in heart failure with DCM, and may be involved in the immune and inflammation response to heart failure.
    MeSH term(s) Humans ; Cardiomyopathy, Dilated/diagnosis ; Cardiomyopathy, Dilated/genetics ; Cardiomyopathy, Dilated/metabolism ; Gene Expression Profiling ; Heart Failure/diagnosis ; Heart Failure/genetics ; Inflammation ; Sequence Analysis, RNA ; Neurons/metabolism
    Language English
    Publishing date 2024-02-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059859-2
    ISSN 1471-2261 ; 1471-2261
    ISSN (online) 1471-2261
    ISSN 1471-2261
    DOI 10.1186/s12872-024-03739-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Isolated Unilateral Horizontal Semicircular Canal Malformation.

    Liu, Yi-Wei / Sun, Ke / Tang, Jian-Guo

    Chinese medical journal

    2018  Volume 131, Issue 6, Page(s) 743–745

    MeSH term(s) Humans ; Semicircular Canals/abnormalities
    Language English
    Publishing date 2018-03-09
    Publishing country China
    Document type Letter
    ZDB-ID 127089-8
    ISSN 0366-6999 ; 1002-0187
    ISSN 0366-6999 ; 1002-0187
    DOI 10.4103/0366-6999.226895
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The protective effect of 999 XiaoErGanMao granules on the lungs and intestines of influenza A virus-infected mice.

    Hao, Yuan-Zhen / Cen, Li-Feng / Wang, Ting / Yi, Tong / Shi, Xun-Long / Duan, Hui-Juan / Dai, Zhi / Zhu, Hai-Yan / Tang, Jian-Guo

    Pharmaceutical biology

    2023  Volume 61, Issue 1, Page(s) 630–638

    Abstract: Context: Gastrointestinal symptoms are a common complication of influenza virus infection in children, which the gut-lung axis become involved in its biological progress. The protective effect of 999 XiaoErGanMao granules (XEGMG) on multi-organ injury ... ...

    Abstract Context: Gastrointestinal symptoms are a common complication of influenza virus infection in children, which the gut-lung axis become involved in its biological progress. The protective effect of 999 XiaoErGanMao granules (XEGMG) on multi-organ injury in viral pneumonia remains unclear.
    Objective: To investigate the therapeutic effect of XEGMG on lungs and intestines injury in A/FM/1/47 (H1N1) influenza virus-infected mice.
    Materials and methods: Male BALB/c mice were infected with the 2LD
    Results: Treating with XEGMG (12 g/kg) can mitigate body weight loss caused by 2LD
    Discussion and conclusions: XEGMG can protect against H1N1 invasion involved in gut-lung axis regulation. The results provide new evidence for the protective effect of XEGMG, which is beneficial to vulnerable children.
    MeSH term(s) Male ; Animals ; Mice ; Influenza A virus/metabolism ; Influenza A Virus, H1N1 Subtype ; Lung ; Cytokines/metabolism ; Intestines ; Mice, Inbred BALB C
    Chemical Substances Cytokines
    Language English
    Publishing date 2023-04-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 1440131-9
    ISSN 1744-5116 ; 1388-0209
    ISSN (online) 1744-5116
    ISSN 1388-0209
    DOI 10.1080/13880209.2023.2195884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Preparation of graphene oxide/silica hybrid composite membranes and performance studies in water treatment

    Du, Ying-chen / Huang, Lin-jun / Wang, Yan-xin / Yang, Kun / Zhang, Zhi-jie / Wang, Yao / Kipper, Matt J / Belfiore, Laurence A / Tang, Jian-guo

    Journal of materials science. 2020 Sept., v. 55, no. 25

    2020  

    Abstract: Water shortages have become a major problem facing the world today. Membrane separation technology is commonly used in water treatment applications. The development of new materials for water treatment can reduce the energy required for water treatment, ... ...

    Abstract Water shortages have become a major problem facing the world today. Membrane separation technology is commonly used in water treatment applications. The development of new materials for water treatment can reduce the energy required for water treatment, reduce cost, and improve efficiency. The unique structure and properties of graphene and silica make them attractive materials for preparation of nanofiltration membranes for water treatment. We have successfully prepared a graphene oxide/silica (GO/SiO₂) hybrid composite materials by in situ hydrolysis, using tetraethyl orthosilicate (TEOS) as a silicon source in an alkaline environment. The chemistry and structure of these materials are characterized by TEM, FTIR, Raman, and XPS of GO and the GO/SiO₂ composite. BET porosimetry reveals that the total pore volume of the composite is 2.84 cm³ g⁻¹, the specific surface area is 2897 m² g⁻¹, and the average pore diameter is 3.97 nm. We prepared GO membranes and GO/SiO₂ composite membranes by vacuum suction filtration. The morphology of the membrane was observed by FESEM and AFM. The composite membrane has a larger surface roughness (Rₘₛ = 9.39). We also tested the thermal stability by TGA, and hydrophilicity by water contact angle measurements. The water permeance of the composite membrane is up to 229.15 L m⁻² h⁻¹ bar⁻¹, and the rejection of the rhodamine B dye molecules is as high as 99%. The GO/SiO₂ hybrid composite membrane has good hydrophilicity and thermal stability, high water permeance and rejection, and can be developed as a high-performance material for water treatment.
    Keywords asymmetric membranes ; contact angle ; cost effectiveness ; dyes ; energy ; graphene ; graphene oxide ; hydrolysis ; hydrophilicity ; nanofiltration ; porosimetry ; rhodamines ; silica ; silicon ; surface area ; surface roughness ; thermal stability ; water treatment
    Language English
    Dates of publication 2020-09
    Size p. 11188-11202.
    Publishing place Springer US
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2015305-3
    ISSN 1573-4803 ; 0022-2461
    ISSN (online) 1573-4803
    ISSN 0022-2461
    DOI 10.1007/s10853-020-04774-5
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: A review of performance improvement strategies for graphene oxide-based and graphene-based membranes in water treatment

    Han, Zhen-yang / Huang, Lin-jun / Qu, Huai-jiao / Wang, Yan-xin / Zhang, Zhi-jie / Rong, Qing-lin / Sang, Zi-qi / Wang, Yao / Kipper, Matt J / Tang, Jian-guo

    Journal of materials science. 2021 June, v. 56, no. 16

    2021  

    Abstract: In the past few decades, due to the rapid development of industry and the rapid growth of population, emissions of pollutants to the environment have increased dramatically, and the demand for drinking water is also increasing. Water treatment is a ... ...

    Abstract In the past few decades, due to the rapid development of industry and the rapid growth of population, emissions of pollutants to the environment have increased dramatically, and the demand for drinking water is also increasing. Water treatment is a matter of concern because it is directly related to the health of humans and wildlife. Graphene and its derivatives have potential applications in seawater desalination and wastewater treatment due to their unique pore structure and ionic molecular sieving separation capabilities. Graphene, graphene oxide (GO), and reduced graphene oxide (rGO) can be formulated into nanoporous materials and composites with tunable properties that can be optimized for water filtration. Methods for perforating graphene include ion etching/ion bombardment and electron beam nanometer engraving, which are briefly introduced in this paper. Graphene-based composites further expand the capabilities of graphene in seawater desalination and wastewater treatment, by introducing new features and properties. In this review, the performance improvement of graphene-based separation membranes in decontamination and desalination in recent years is reviewed in detail. This review focuses on improving the performance of graphene-based membranes for separation, decontamination, and seawater desalination applications, by discussing how various modifications and preparation methods impact important performance properties, including water permeance, selectivity, rejection of solutes, membrane mechanical strength, and antifouling characteristics. We also discuss the outlook for future development of graphene-based membranes.
    Keywords decontamination ; desalination ; filtration ; graphene ; graphene oxide ; industry ; nanopores ; seawater ; strength (mechanics) ; wastewater treatment ; wildlife
    Language English
    Dates of publication 2021-06
    Size p. 9545-9574.
    Publishing place Springer US
    Document type Article
    Note NAL-AP-2-clean ; Review
    ZDB-ID 2015305-3
    ISSN 1573-4803 ; 0022-2461
    ISSN (online) 1573-4803
    ISSN 0022-2461
    DOI 10.1007/s10853-021-05873-7
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: [Bamboo nodes on the vocal cord and autoimmune disease].

    Lu, Juan / Tang, Jian-guo

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2009  Volume 44, Issue 4, Page(s) 346–348

    MeSH term(s) Autoimmune Diseases ; Humans ; Laryngeal Diseases ; Sarcoidosis ; Vocal Cords/pathology
    Language Chinese
    Publishing date 2009-04
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article: Effect of Candida albicans on Intestinal Ischemia-reperfusion Injury in Rats.

    Yan, Lei / Wu, Chun-Rong / Wang, Chen / Yang, Chun-Hui / Tong, Guang-Zhi / Tang, Jian-Guo

    Chinese medical journal

    2016  Volume 129, Issue 14, Page(s) 1711–1718

    Abstract: Background: Inflammation is supposed to play a key role in the pathophysiological processes of intestinal ischemia-reperfusion injury (IIRI), and Candida albicans in human gut commonly elevates inflammatory cytokines in intestinal mucosa. This study ... ...

    Abstract Background: Inflammation is supposed to play a key role in the pathophysiological processes of intestinal ischemia-reperfusion injury (IIRI), and Candida albicans in human gut commonly elevates inflammatory cytokines in intestinal mucosa. This study aimed to explore the effect of C. albicans on IIRI.
    Methods: Fifty female Wistar rats were divided into five groups according to the status of C. albicans infection and IIRI operation: group blank and sham; group blank and IIRI; group cefoperazone plus IIRI; group C. albicans plus cefoperazone and IIRI (CCI); and group C. albicans plus cefoperazone and sham. The levels of inflammatory factors tumor necrosis factor (TNF)-μ, interleukin (IL)-6, IL-1β, and diamine oxidase (DAO) measured by enzyme-linked immunosorbent assay were used to evaluate the inflammation reactivity as well as the integrity of small intestine. Histological scores were used to assess the mucosal damage, and the C. albicans blood translocation was detected to judge the permeability of intestinal mucosal barrier.
    Results: The levels of inflammatory factors TNF-μ, IL-6, and IL-1β in serum and intestine were higher in rats undergone both C. albicans infection and IIRI operation compared with rats in other groups. The levels of DAO (serum: 44.13 ± 4.30 pg/ml, intestine: 346.21 ± 37.03 pg/g) and Chiu scores (3.41 ± 1.09) which reflected intestinal mucosal disruption were highest in group CCI after the operation. The number of C. albicans translocated into blood was most in group CCI ([33.80 ± 6.60] ×102 colony forming unit (CFU)/ml).
    Conclusion: Intestinal C. albicans infection worsened the IIRI-induced disruption of intestinal mucosal barrier and facilitated the subsequent C. albicans translocation and dissemination.
    MeSH term(s) Amine Oxidase (Copper-Containing)/metabolism ; Animals ; Anti-Bacterial Agents/pharmacology ; Candida albicans/drug effects ; Candida albicans/pathogenicity ; Cefoperazone/pharmacology ; Enzyme-Linked Immunosorbent Assay ; Female ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Intestines/drug effects ; Intestines/immunology ; Intestines/metabolism ; Rats ; Rats, Wistar ; Reperfusion Injury/immunology ; Reperfusion Injury/metabolism ; Reperfusion Injury/microbiology
    Chemical Substances Anti-Bacterial Agents ; Interleukin-1beta ; Interleukin-6 ; Cefoperazone (7U75I1278D) ; Amine Oxidase (Copper-Containing) (EC 1.4.3.21)
    Language English
    Publishing date 2016-07-20
    Publishing country China
    Document type Journal Article
    ZDB-ID 127089-8
    ISSN 0366-6999 ; 1002-0187
    ISSN 0366-6999 ; 1002-0187
    DOI 10.4103/0366-6999.185862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Transnasal endoscopic treatment of epidermoid cyst of middle cranial base report of a case].

    Li, Xuan / Tang, Jian-guo

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2007  Volume 42, Issue 7, Page(s) 541

    MeSH term(s) Endoscopy/methods ; Epidermal Cyst/surgery ; Female ; Humans ; Middle Aged ; Skull Base/pathology
    Language Chinese
    Publishing date 2007-07
    Publishing country China
    Document type Case Reports ; Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
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  9. Article: [The effect of aerosolized antibiotic therapy on ventilator associated pneumonia].

    Li, Hu / Yang, Chun-hui / Tang, Jian-guo

    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue

    2011  Volume 23, Issue 1, Page(s) 60–62

    MeSH term(s) Aerosols/administration & dosage ; Aerosols/adverse effects ; Aerosols/therapeutic use ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/adverse effects ; Anti-Bacterial Agents/therapeutic use ; Humans ; Pneumonia, Ventilator-Associated/drug therapy ; Ventilators, Mechanical/adverse effects
    Chemical Substances Aerosols ; Anti-Bacterial Agents
    Language Chinese
    Publishing date 2011-01
    Publishing country China
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ISSN 1003-0603
    ISSN 1003-0603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Graphene Oxide Nanofiltration Membranes Containing Silver Nanoparticles: Tuning Separation Efficiency via Nanoparticle Size.

    Yang, Kun / Huang, Lin-Jun / Wang, Yan-Xin / Du, Ying-Chen / Zhang, Zhi-Jie / Wang, Yao / Kipper, Matt J / Belfiore, Laurence A / Tang, Jian-Guo

    Nanomaterials (Basel, Switzerland)

    2020  Volume 10, Issue 3

    Abstract: Three types of graphene oxide/silver nanoparticles (GO/AgNPs) composite membranes were prepared to investigate size-effect of AgNPs on nanofiltration ability. The size of AgNPs was 8, 20, and 33 nm, which was characterized by UV-visible spectroscopy and ... ...

    Abstract Three types of graphene oxide/silver nanoparticles (GO/AgNPs) composite membranes were prepared to investigate size-effect of AgNPs on nanofiltration ability. The size of AgNPs was 8, 20, and 33 nm, which was characterized by UV-visible spectroscopy and transmission electron microscopy. The morphology and structure of GO and GO/AgNPs composite membranes were characterized by atomic force microscopy, scanning electron microscopy, and X-ray diffraction. The filtration performance of membranes were evaluated on a dead-end filtration device. When the size of AgNPs is 20 nm, the GO/AgNPs composite membrane has the highest water flux (106.1 L m
    Language English
    Publishing date 2020-03-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano10030454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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