Article ; Online: Deacetylase Sirtuin 1 mitigates type I IFN- and type II IFN-induced signaling and antiviral immunity.
2024 Volume 98, Issue 3, Page(s) e0008824
Abstract: Type I and type II IFNs are important immune modulators in both innate and adaptive immunity. They transmit signaling by activating JAK-STAT pathways. Sirtuin 1 (SIRT1), a class III ... ...
Abstract | Type I and type II IFNs are important immune modulators in both innate and adaptive immunity. They transmit signaling by activating JAK-STAT pathways. Sirtuin 1 (SIRT1), a class III NAD |
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MeSH term(s) | Animals ; Mice ; Immunity, Innate ; Interferon Type I/metabolism ; Interferon-gamma ; Phosphorylation ; Signal Transduction ; Sirtuin 1/genetics ; Sirtuin 1/metabolism ; STAT1 Transcription Factor/metabolism ; Virus Diseases/immunology |
Chemical Substances | Interferon Type I ; Interferon-gamma (82115-62-6) ; Sirtuin 1 (EC 3.5.1.-) ; STAT1 Transcription Factor ; Sirt1 protein, mouse (EC 3.5.1.-) |
Language | English |
Publishing date | 2024-02-22 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 80174-4 |
ISSN | 1098-5514 ; 0022-538X |
ISSN (online) | 1098-5514 |
ISSN | 0022-538X |
DOI | 10.1128/jvi.00088-24 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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