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Article ; Online: An Improved YOLOv5 Algorithm for Vulnerable Road User Detection.

Yang, Wei / Tang, Xiaolin / Jiang, Kongming / Fu, Yang / Zhang, Xinling

2023 Volume 23, Issue 18

Abstract: The vulnerable road users (VRUs), being small and exhibiting random movements, increase the difficulty of object detection of the autonomous emergency braking system for vulnerable road users AEBS-VRUs, with their behaviors highly random. To overcome ... ...

Abstract	The vulnerable road users (VRUs), being small and exhibiting random movements, increase the difficulty of object detection of the autonomous emergency braking system for vulnerable road users AEBS-VRUs, with their behaviors highly random. To overcome existing problems of AEBS-VRU object detection, an enhanced YOLOv5 algorithm is proposed. While the Complete Intersection over Union-Loss (CIoU-Loss) and Distance Intersection over Union-Non-Maximum Suppression (DIoU-NMS) are fused to improve the model's convergent speed, the algorithm also incorporates a minor object detection layer to increase the performance of VRU detection. A dataset for complex AEBS-VRUS scenarios is established based on existing datasets such as Caltech, nuScenes, and Penn-Fudan, and the model is trained using migration learning based on the PyTorch framework. A number of comparative experiments using models such as YOLOv6, YOLOv7, YOLOv8 and YOLOx are carried out. The results of the comparative evaluation show that the proposed improved YOLO5 algorithm has the best overall performance in terms of efficiency, accuracy and timeliness of target detection.
Language	English
Publishing date	2023-09-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23187761
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Article ; Online: Extraction, separation and kinetics of phenylethanosides from

Feng, Chuanhua / Guo, Huiling / Zhao, Xiaojuan / Tang, Xiaolin / Xiong, Yaokun

Preparative biochemistry & biotechnology

2023 Volume 53, Issue 8, Page(s) 978–987

Abstract: In this paper, the total phenylethanosides (TPS) were extracted efficiently by an innovative extraction technology--deep eutectic solvent-based ultrasound-assisted extraction (DES-UAE) ... ...

Abstract	In this paper, the total phenylethanosides (TPS) were extracted efficiently by an innovative extraction technology--deep eutectic solvent-based ultrasound-assisted extraction (DES-UAE) from
MeSH term(s)	Solvents ; Flavonoids ; Deep Eutectic Solvents ; Plantago ; Methanol ; Kinetics ; Water ; Technology ; Ethanol ; Plant Extracts
Chemical Substances	Solvents ; Flavonoids ; Deep Eutectic Solvents ; Methanol (Y4S76JWI15) ; Water (059QF0KO0R) ; Ethanol (3K9958V90M) ; Plant Extracts
Language	English
Publishing date	2023-01-31
Publishing country	England
Document type	Journal Article
ZDB-ID	1322522-4
ISSN	1532-2297 ; 1082-6068
ISSN (online)	1532-2297
ISSN	1082-6068
DOI	10.1080/10826068.2022.2163257
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Article ; Online: Extraction, separation and kinetics of phenylethanosides from Plantago asiatica L. by an innovative extraction technology—deep eutectic solvent-based ultrasound-assisted extraction

Feng, Chuanhua / Guo, Huiling / Zhao, Xiaojuan / Tang, Xiaolin / Xiong, Yaokun

Preparative Biochemistry & Biotechnology. 2023 Sept. 1, v. 53, no. 8 p.978-987

2023

Abstract: In this paper, the total phenylethanosides (TPS) were extracted efficiently by an innovative extraction technology––deep eutectic solvent-based ultrasound-assisted extraction (DES-UAE) from Plantago asiatica L. Ten diverse types of DESs were synthesized ... ...

Abstract	In this paper, the total phenylethanosides (TPS) were extracted efficiently by an innovative extraction technology––deep eutectic solvent-based ultrasound-assisted extraction (DES-UAE) from Plantago asiatica L. Ten diverse types of DESs were synthesized as alternative extraction solutions. The extraction efficiency of DES-3 (constituted by choline chloride and lactic acid) was much higher than those of other DESs. On the basis of single factor tests and Box-Behnken design (BBD), the optimum processing parameters of DES-UAE as follow: DES-3 with molar ratio of 1:3, extraction temperature 51 °C, solid/liquid 22.5 mg/ml, water content 30%, ultrasonic power 65 W, extraction time 23 min. The extraction efficiency of TPS from Plantago asiatica L. was 8.395 mg/ml, which was more superior than those of organic solvents (water, methanol, 50% methanol, ethanol, 50% ethanol). The extraction kinetics experiment results showed that water content had a significant influence upon the extraction efficiency of TPS. At the same time, AB-8 macroporous resin column was used to efficiently isolate TPS from DES extraction with a recovery rate of 88.5%.
Keywords	Plantago asiatica ; biochemistry ; biotechnology ; choline chloride ; ethanol ; experimental design ; lactic acid ; liquids ; methanol ; porous media ; temperature ; ultrasonic treatment ; ultrasonics ; water content ; Plantago asiatica L. ; deep eutectic solvent ; ultrasound-assisted extraction ; kinetics ; phenylethanosides
Language	English
Dates of publication	2023-0901
Size	p. 978-987.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	1322522-4
ISSN	1532-2297 ; 1082-6068
ISSN (online)	1532-2297
ISSN	1082-6068
DOI	10.1080/10826068.2022.2163257
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Article ; Online: Battery thermal- and cabin comfort-aware collaborative energy management for plug-in fuel cell electric vehicles based on the soft actor-critic algorithm

Deng, Lei / Li, Shen / Tang, Xiaolin / Yang, Kai / Lin, Xianke

Energy Conversion and Management. 2023 May, v. 283 p.116889-

2023

Abstract: While the air conditioning system provides a comfortable thermal environment for vehicle occupants, it is also one of the most energy-intensive auxiliary devices in modern vehicles. Meanwhile, the operating characteristic of the battery system ... ...

Abstract	While the air conditioning system provides a comfortable thermal environment for vehicle occupants, it is also one of the most energy-intensive auxiliary devices in modern vehicles. Meanwhile, the operating characteristic of the battery system significantly impacts the economic and safety performance of the vehicle. To improve the energy efficiency of plug-in fuel cell electric vehicles, this paper proposes a collaborative energy management strategy based on the soft actor-critic algorithm, considering battery thermal management and cabin thermal comfort management. First, the soft actor-critic algorithm is implemented in energy management research for fuel cell electric vehicles. Second, by establishing a control-oriented vehicle-integrated thermal management model and adopting a novel air conditioning system design, the coordinated optimization of the battery thermal management and cabin thermal comfort management is achieved. Finally, the collaborative energy management strategy based on the soft actor-critic algorithm is presented to minimize the total operating cost, while maintaining the optimal battery temperature range and cabin thermal comfort. The online testing results demonstrate that the implemented energy management strategy based on the soft actor-critic algorithm can achieve 96.06% fuel economy of the dynamic programming benchmark methodology, while significantly improving computational efficiency. Moreover, the proposed collaborative energy management strategy can effectively improve the overall vehicle fuel economy, manage the battery temperature within the optimal operating range, and maintain cabin thermal comfort. However, with the prolonged operation of the air conditioning system, the total operating cost of the vehicle increases considerably, up to 28.12% or even more, indicating that it is a highly energy-consuming component.
Keywords	administrative management ; air ; algorithms ; batteries ; energy efficiency ; fuel cells ; fuels ; models ; systems engineering ; temperature ; Plug-in fuel cell electric vehicle ; Energy management strategy ; Battery thermal management ; Cabin thermal comfort ; Air conditioning system ; Soft actor-critic
Language	English
Dates of publication	2023-05
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	2000891-0
ISSN	0196-8904
ISSN	0196-8904
DOI	10.1016/j.enconman.2023.116889
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Article ; Online: Polyetherimide- and folic acid-modified Fe

Wang, Qinganzi / Cheng, Yuemei / Wang, Wenhua / Tang, Xiaolin / Yang, Yongxiu

Journal of biomedical materials research. Part B, Applied biomaterials

2022 Volume 111, Issue 4, Page(s) 795–804

Abstract: Recent studies have highlighted the development prospects of magnetic hyperthermia in cancer therapy. A few studies on the application of ... ...

Abstract	Recent studies have highlighted the development prospects of magnetic hyperthermia in cancer therapy. A few studies on the application of Fe
MeSH term(s)	Animals ; Mice ; Humans ; Nanospheres ; Folic Acid/pharmacology ; NIH 3T3 Cells ; Hyperthermia, Induced/methods ; Magnetic Phenomena
Chemical Substances	polyetherimide ; Folic Acid (935E97BOY8)
Language	English
Publishing date	2022-11-16
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2099992-6
ISSN	1552-4981 ; 1552-4973 ; 0021-9304
ISSN (online)	1552-4981
ISSN	1552-4973 ; 0021-9304
DOI	10.1002/jbm.b.35190
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Article ; Online: Advanced MRI features of intraventricular inflammatory myofibroblastic tumor: a case report.

Tang, Xiao-Lin / Huang, Wen-Jun / Ma, Qiang / Yi, Kun-Ming

BMC neurology

2022 Volume 22, Issue 1, Page(s) 448

Abstract: Background: Inflammatory myofibroblastic tumor (IMT) is a rare central nervous system (CNS) tumor. We first report a rare case of IMT in the lateral ventricle and describe the magnetic resonance imaging (MRI) findings of the tumor with an emphasis on ... ...

Abstract	Background: Inflammatory myofibroblastic tumor (IMT) is a rare central nervous system (CNS) tumor. We first report a rare case of IMT in the lateral ventricle and describe the magnetic resonance imaging (MRI) findings of the tumor with an emphasis on the advanced MRI features. Case presentation: A 49-year-old female patient with headaches and blurred vision for 2 months. Brain MRI revealed a well-circumscribed, lobulated mass occupying the left lateral ventricle trigone, with marked perilesional brain edema. The tumor showed heterogeneous significant hyperintensity on T2-weighted imaging (T2WI) and hypointensity on T1-weighted imaging (T1WI). After the administration of gadolinium, the mass exhibited marked contrast enhancement and the halo sign was observed. On advanced MRI, the lesion showed decreased perfusion on perfusion MRI and reduced diffusion on diffusion-weighted imaging (DWI). On susceptibility-weighted imaging (SWI), there was a punctate low signal intensity in the tumor. The patient underwent surgical resection of the mass and a pathological examination confirmed the lesion to be an inflammatory myofibroblastic tumor with negative expression of anaplastic lymphoma kinase (ALK). This patient had remained healthy without evidence of recurrence during a 20-month follow-up. Conclusions: On MRI, marked perilesional brain edema, significant hyperintensity on T2WI, hypoperfusion on perfusion MRI but with an obvious enhancement, no diffusion restriction on DWI, and halo sign may be the characteristic findings of intraventricular IMT. The advanced MRI characteristics could provide abundant information to reflect the histological features and physiological metabolic characteristics of the tumor.
MeSH term(s)	Female ; Humans ; Middle Aged ; Brain Edema ; Magnetic Resonance Imaging ; Gadolinium ; Diffusion Magnetic Resonance Imaging ; Magnetic Resonance Angiography
Chemical Substances	Gadolinium (AU0V1LM3JT)
Language	English
Publishing date	2022-12-02
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2041347-6
ISSN	1471-2377 ; 1471-2377
ISSN (online)	1471-2377
ISSN	1471-2377
DOI	10.1186/s12883-022-02993-8
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Article ; Online: Gingipains may be one of the key virulence factors of Porphyromonas gingivalis to impair cognition and enhance blood-brain barrier permeability: An animal study.

Li, Fulong / Ma, Chunliang / Lei, Shuang / Pan, Yaping / Lin, Li / Pan, Chunling / Li, Qian / Geng, Fengxue / Min, Dongyu / Tang, Xiaolin

Journal of clinical periodontology

2024

Abstract: Aim: Blood-brain barrier (BBB) disorder is one of the early findings in cognitive impairments. We have recently found that Porphyromonas gingivalis bacteraemia can cause cognitive impairment and increased BBB permeability. This study aimed to find out ... ...

Abstract	Aim: Blood-brain barrier (BBB) disorder is one of the early findings in cognitive impairments. We have recently found that Porphyromonas gingivalis bacteraemia can cause cognitive impairment and increased BBB permeability. This study aimed to find out the possible key virulence factors of P. gingivalis contributing to the pathological process. Materials and methods: C57/BL6 mice were infected with P. gingivalis or gingipains or P. gingivalis lipopolysaccharide (P. gingivalis LPS group) by tail vein injection for 8 weeks. The cognitive behaviour changes in mice, the histopathological changes in the hippocampus and cerebral cortex, the alternations of BBB permeability, and the changes in Mfsd2a and Cav-1 levels were measured. The mechanisms of Ddx3x-induced regulation on Mfsd2a by arginine-specific gingipain A (RgpA) in BMECs were explored. Results: P. gingivalis and gingipains significantly promoted mice cognitive impairment, pathological changes in the hippocampus and cerebral cortex, increased BBB permeability, inhibited Mfsd2a expression and up-regulated Cav-1 expression. After RgpA stimulation, the permeability of the BBB model in vitro increased, and the Ddx3x/Mfsd2a/Cav-1 regulatory axis was activated. Conclusions: Gingipains may be one of the key virulence factors of P. gingivalis to impair cognition and enhance BBB permeability by the Ddx3x/Mfsd2a/Cav-1 axis.
Language	English
Publishing date	2024-02-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	188647-2
ISSN	1600-051X ; 0303-6979
ISSN (online)	1600-051X
ISSN	0303-6979
DOI	10.1111/jcpe.13966
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Zs.A 1003: Show issues

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Article ; Online: Characterization of a novel gammapartitivirus infecting the phytopathogenic fungus Pyricularia oryzae.

Fan, Yu / Zhao, Wenhua / Tang, XiaoLin / Wang, Li / Yang, Mei / Yang, Yingqing / Cheng, Baoping / Zhou, Erxun / He, Zhenrui

Archives of virology

2024 Volume 169, Issue 5, Page(s) 105

Abstract: In this study, we identified a novel double-strand RNA (dsRNA) mycovirus in Pyricularia oryzae, designated "Magnaporthe oryzae partitivirus 4" (MoPV4). The genome of MoPV4 consists of a dsRNA-1 segment encoding an RNA-dependent RNA polymerase (RdRP) and ... ...

Abstract	In this study, we identified a novel double-strand RNA (dsRNA) mycovirus in Pyricularia oryzae, designated "Magnaporthe oryzae partitivirus 4" (MoPV4). The genome of MoPV4 consists of a dsRNA-1 segment encoding an RNA-dependent RNA polymerase (RdRP) and a dsRNA-2 segment encoding a capsid protein (CP). Phylogenetic analysis indicated that MoPV4 belongs to the genus Gammapartitivirus within family Partitiviridae. The particles of MoPV4 are isometric with a diameter of about 32.4 nm. Three-dimensional structure predictions indicated that the RdRP of MoPV4 forms a classical right-handed conformation, while the CP has a reclining-V shape.
MeSH term(s)	RNA, Viral/genetics ; Phylogeny ; RNA Viruses/genetics ; Ascomycota ; Capsid Proteins/genetics ; RNA-Dependent RNA Polymerase/genetics ; Genome, Viral ; Fungal Viruses/genetics ; RNA, Double-Stranded/genetics ; Open Reading Frames
Chemical Substances	RNA, Viral ; Capsid Proteins ; RNA-Dependent RNA Polymerase (EC 2.7.7.48) ; RNA, Double-Stranded
Language	English
Publishing date	2024-04-18
Publishing country	Austria
Document type	Journal Article
ZDB-ID	7491-3
ISSN	1432-8798 ; 0304-8608
ISSN (online)	1432-8798
ISSN	0304-8608
DOI	10.1007/s00705-024-06031-5
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Article: Calcitriol-enhanced autophagy in gingival epithelium attenuates periodontal inflammation in rats with type 2 diabetes mellitus.

Wang, Yanan / Huang, Maoting / Xu, Wanlin / Li, Fulong / Ma, Chunliang / Tang, Xiaolin

Frontiers in endocrinology

2023 Volume 13, Page(s) 1051374

Abstract: Type 2 diabetes mellitus (T2DM)-associated periodontitis is a common disease with high prevalence, associated with persistent infection and complicated manifestations. Calcitriol (1 alpha, 25-dihydroxyvitamin D3, 1,25D) is the active form of vitamin D ... ...

Abstract	Type 2 diabetes mellitus (T2DM)-associated periodontitis is a common disease with high prevalence, associated with persistent infection and complicated manifestations. Calcitriol (1 alpha, 25-dihydroxyvitamin D3, 1,25D) is the active form of vitamin D that plays a protective role in immune regulation, bone metabolism, and inflammatory response. In this study, we constructed a T2DM model in rats by combining a high-fat diet with low-dose streptozotocin. The periodontitis model in rats was developed by ligation and
MeSH term(s)	Rats ; Humans ; Animals ; Calcitriol/pharmacology ; Calcitriol/therapeutic use ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Inflammation/drug therapy ; Inflammation/complications ; Epithelium/metabolism ; Periodontitis/complications ; Periodontitis/drug therapy ; Autophagy ; Anti-Bacterial Agents/pharmacology
Chemical Substances	Calcitriol (FXC9231JVH) ; Anti-Bacterial Agents
Language	English
Publishing date	2023-01-10
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2022.1051374
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Article: Convex optimization-based predictive and bi-level energy management for plug-in hybrid electric vehicles

Li, Yapeng / Wang, Feng / Tang, Xiaolin / Hu, Xiaosong / Lin, Xianke

Energy. 2022 Oct. 15, v. 257

2022

Abstract: Energy management is one of the key technologies to improve the energy efficiency of electrified vehicles. In the existing real-time powertrain control strategies, most studies focus on improving fuel economy based on high-fidelity powertrain models ... ...

Abstract	Energy management is one of the key technologies to improve the energy efficiency of electrified vehicles. In the existing real-time powertrain control strategies, most studies focus on improving fuel economy based on high-fidelity powertrain models without adequately exploring the impact of model accuracy on computational efficiency and energy saving. To address this research gap, this paper proposes a hierarchical control framework to minimize the fuel consumption of a plug-in hybrid electric vehicle. Specifically, three main contributions are presented to distinguish our efforts from existing research. First, two types of powertrain models are used in the optimization framework. In the upper control layer, an approximated model is employed to generate the optimal reference state of charge trajectory using convex optimization. Then in the lower control layer, by integrating the equivalent consumption minimize strategy into the model predictive control framework, the fuel consumption is minimized in real-time by using a high-fidelity powertrain model. Second, optimization results from the other three real-time control strategies and two predictive energy management strategies are presented and analyzed to verify the effectiveness of the proposed method. Finally, the robustness with respect to prediction horizon length, initial co-state value, and gain coefficient value are discussed.
Keywords	energy efficiency ; energy use and consumption ; models ; vehicles (equipment)
Language	English
Dates of publication	2022-1015
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	2019804-8
ISSN	0360-5442 ; 0360-5442
ISSN (online)	0360-5442
ISSN	0360-5442
DOI	10.1016/j.energy.2022.124672
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