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Article ; Online: Spatial temporal Fourier single-pixel imaging.

Tang, Zixin / Tang, Tianhang / Chen, Jie / Lv, Shun / Liu, Yiguang

Optics letters

2023 Volume 48, Issue 8, Page(s) 2066–2069

Abstract: Generally, the imaging quality of Fourier single-pixel imaging (FSI) will severely degrade while achieving high-speed imaging at a low sampling rate (SR). To tackle this problem, a new, to the best of our knowledge, imaging technique is proposed: firstly, ...

Abstract	Generally, the imaging quality of Fourier single-pixel imaging (FSI) will severely degrade while achieving high-speed imaging at a low sampling rate (SR). To tackle this problem, a new, to the best of our knowledge, imaging technique is proposed: firstly, the Hessian-based norm constraint is introduced to deal with the staircase effect caused by the low SR and total variation regularization; secondly, based on the local similarity prior of consecutive frames in the time dimension, we designed the temporal local image low-rank constraint for the FSI, and combined the spatiotemporal random sampling method, the redundancy image information of consecutive frames can be utilized sufficiently; finally, by introducing additional variables to decompose the optimization problem into multiple sub-problems and analytically solving each one, a closed-form algorithm is derived for efficient image reconstruction. Experimental results show that the proposed method improves imaging quality significantly compared with state-of-the-art methods.
Language	English
Publishing date	2023-03-13
Publishing country	United States
Document type	Journal Article
ISSN	1539-4794
ISSN (online)	1539-4794
DOI	10.1364/OL.480190
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Fast and high-quality single-pixel imaging.

Tang, Zixin / Tang, Tianhang / Shi, Xuelei / Chen, Jie / Liu, Yiguang

Optics letters

2022 Volume 47, Issue 5, Page(s) 1218–1221

Abstract: The imaging quality of the conventional single-pixel-imaging (SPI) technique seriously degrades at a low sampling rate. To tackle this problem, we propose an efficient sampling method and a high-quality real-time image reconstruction strategy: first, ... ...

Abstract	The imaging quality of the conventional single-pixel-imaging (SPI) technique seriously degrades at a low sampling rate. To tackle this problem, we propose an efficient sampling method and a high-quality real-time image reconstruction strategy: first, different from the conventional simple circular path sampling strategy or variable density random sampling technique, the proposed method samples the Fourier spectrum using the spectrum distribution of the image, that is, sampling the significant spectrum coefficients first, which will help to improve the image quality at a relevantly low sampling rate; second, to handle the long image reconstruction time caused by the iterative algorithm, the sparsity of the image and the alternating direction optimization strategy are combined to ameliorate the reconstruction process in the image gradient space. Compared with the state-of-the-art techniques, the proposed method significantly improves the imaging quality and achieves real-time reconstruction on the time scale of milliseconds.
Language	English
Publishing date	2022-02-18
Publishing country	United States
Document type	Journal Article
ISSN	1539-4794
ISSN (online)	1539-4794
DOI	10.1364/OL.448658
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: High-speed three-dimensional shape measurement based on tripartite complementary Gray-coded light.

Li, Dongsong / Chen, Jie / Tang, Tianhang / Shi, Xuelei / Tang, Zixin / Liu, Yiguang

Applied optics

2022 Volume 61, Issue 17, Page(s) 5083–5089

Abstract: In phase-shifting profilometry based on the Gray code, the jump error is inevitably generated and is further amplified in dynamic scenes. To tackle this problem, we propose the robust tripartite complementary Gray code method (TCG). Without projecting ... ...

Abstract	In phase-shifting profilometry based on the Gray code, the jump error is inevitably generated and is further amplified in dynamic scenes. To tackle this problem, we propose the robust tripartite complementary Gray code method (TCG). Without projecting additional patterns, TCG uses different combinations of Gray code to calculate three complementary orders able to avoid jump error in the unwrapping process. TCG is efficient and robust, as it fully utilizes the redundant information of the Gray code. Experimental results demonstrate that TCG can realize high-efficiency and high-speed three-dimensional shape measurement at a rate of 500 fps.
Language	English
Publishing date	2022-10-03
Publishing country	United States
Document type	Journal Article
ISSN	1539-4522
ISSN (online)	1539-4522
DOI	10.1364/AO.457024
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Article ; Online: Exosome camouflaged coordination-assembled Iridium(III) photosensitizers for apoptosis-autophagy-ferroptosis induced combination therapy against melanoma.

Feng, Tao / Tang, Zixin / Karges, Johannes / Shen, Jinchao / Jin, Chengzhi / Chen, Yu / Pan, Yihang / He, Yulong / Ji, Liangnian / Chao, Hui

Biomaterials

2023 Volume 301, Page(s) 122212

Abstract: Melanoma represents the most fatal form of skin cancer due to its resistance mechanisms and high capacity for the development of metastases. Among other medicinal techniques, photodynamic therapy is receiving increasing attention. Despite promising ... ...

Abstract	Melanoma represents the most fatal form of skin cancer due to its resistance mechanisms and high capacity for the development of metastases. Among other medicinal techniques, photodynamic therapy is receiving increasing attention. Despite promising results, the application of photodynamic therapy is inherently limited due to interference from melanin, poor tissue penetration of photosensitizers, low loading into drug delivery systems, and a lack of tumor selectivity. To overcome these limitations, herein, the coordination-driven assembly of Ir(III) complex photosensitizers with Fe(III) ions into nanopolymers for combined photodynamic therapy and chemodynamic therapy is reported. While remaining stable under physiological conditions, the nanopolymers dissociated in the tumor microenvironment. Upon exposure to light, the Ir(III) complexes produced singlet oxygen and superoxide anion radicals, inducing cell death by apoptosis and autophagy. The Fe(III) ions were reduced to Fe(II) upon depletion of glutathione and reduction of the GPX4 levels, triggering cell death by ferroptosis. To provide tumor selectivity, the nanopolymers were further camouflaged with exosomes. The generated nanoparticles were found to eradicate a melanoma tumor as well as inhibit the formation of metastases inside a mouse model.
MeSH term(s)	Animals ; Mice ; Photosensitizing Agents/therapeutic use ; Photosensitizing Agents/pharmacology ; Iridium ; Ferroptosis ; Exosomes ; Ferric Compounds/therapeutic use ; Neoplasms/drug therapy ; Photochemotherapy/methods ; Melanoma/drug therapy ; Apoptosis ; Cell Line, Tumor ; Tumor Microenvironment
Chemical Substances	Photosensitizing Agents ; Iridium (44448S9773) ; Ferric Compounds
Language	English
Publishing date	2023-06-24
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	603079-8
ISSN	1878-5905 ; 0142-9612
ISSN (online)	1878-5905
ISSN	0142-9612
DOI	10.1016/j.biomaterials.2023.122212
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Book ; Online: Like a bilingual baby

Nguyen, Khai-Nguyen / Tang, Zixin / Mali, Ankur / Kelly, Alex

The advantage of visually grounding a bilingual language model

2022

Abstract: Unlike most neural language models, humans learn language in a rich, multi-sensory and, often, multi-lingual environment. Current language models typically fail to fully capture the complexities of multilingual language use. We train an LSTM language ... ...

Abstract	Unlike most neural language models, humans learn language in a rich, multi-sensory and, often, multi-lingual environment. Current language models typically fail to fully capture the complexities of multilingual language use. We train an LSTM language model on images and captions in English and Spanish from MS-COCO-ES. We find that the visual grounding improves the model's understanding of semantic similarity both within and across languages and improves perplexity. However, we find no significant advantage of visual grounding for abstract words. Our results provide additional evidence of the advantages of visually grounded language models and point to the need for more naturalistic language data from multilingual speakers and multilingual datasets with perceptual grounding. Comment: Preprint, 7 pages, 2 tables, 1 figure
Keywords	Computer Science - Computation and Language
Publishing date	2022-10-11
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Highly hydrostable and flexible opal photonic crystal film for enhanced up-conversion fluorescence sensor of COVID-19 antibody

Hu, Songtao / Li, Yige / Dong, Biao / Tang, Zixin / Zhou, Bingshuai / Wang, Yue / Sun, Liheng / Xu, Lin / Wang, Lin / Zhang, Xueliang / Alifu, Nuernisha / Sun, Liankun / Song, Hongwei

Biosensors and Bioelectronics. 2023 Oct., v. 237 p.115484-

2023

Abstract: Efficient detection of related markers is significant for the early screening of COVID-19. Near infrared (NIR) light excited up-conversion fluorescence probes are ideal for biosensing but limited by the low luminescence efficiency. In this work, a novel ... ...

Abstract	Efficient detection of related markers is significant for the early screening of COVID-19. Near infrared (NIR) light excited up-conversion fluorescence probes are ideal for biosensing but limited by the low luminescence efficiency. In this work, a novel highly stable opal photonic crystal (OPC) structure was designed to provide an OPC effect for up-conversion fluorescence enhancement, and sensitive Novel Coronavirus IgG up-conversion FRET-based sensor was further constructed. For the problems of water stability and mechanical stability of polymer OPC which cannot be solved for a long time, polymer spray combined with a flipped OPC film strategy is presented. Fragmented size OPC film was firmly fixed by polymer modification layer, which gave large size OPC film great water stability, mechanical stability and bending performance without affecting the fluorescence enhancement property. On this basis, the up-conversion emission intensity was enhanced significantly, and fluorescence resonant energy transfer (FRET) based Novel Coronavirus IgG antibody sensor was constructed. Monolayer up-conversion nanoparticles (UCNPs) on the surface of the polydopamine (PDA)/OPC film can make the fluorescent signal more sensitive, and effectively reduce the detection limit. The test device integrating NIR excitation and mobile phone realized the visual fast detection, showing remarkable sensing performance for COVID-19 antibodies with the limit of detection (LOD) of 0.1 ng mL⁻¹. This detection platform will provide a more effective tool for early detection of the novel coronavirus.
Keywords	COVID-19 infection ; Orthocoronavirinae ; antibodies ; biosensors ; detection limit ; emissions factor ; energy transfer ; fluorescence ; mobile telephones ; nanoparticles ; opal ; photons ; polymers ; Large size opal photonic crystal ; Highly water stability ; Flexibility ; Up-conversion fluorescence enhancement ; COVID-19 detection
Language	English
Dates of publication	2023-10
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	1011023-9
ISSN	1873-4235 ; 0956-5663
ISSN (online)	1873-4235
ISSN	0956-5663
DOI	10.1016/j.bios.2023.115484
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Estimation of Vibration Characteristics of a Space Manipulator From Air Bearing Supported Test Data.

Li, Haiquan / Wei, Qingqing / Liang, Jianxun / Ren, Weiyan / Tang, Zixin / Li, Delun

Frontiers in robotics and AI

2021 Volume 8, Page(s) 641165

Abstract: Space manipulators have attracted much attention due to their implications in on-orbit servicing in recent years. Air bearing based support equipment is widely used for ground test to offset the effect of gravity. However, an air bearing support ... ...

Abstract	Space manipulators have attracted much attention due to their implications in on-orbit servicing in recent years. Air bearing based support equipment is widely used for ground test to offset the effect of gravity. However, an air bearing support introduces a new problem caused by additional inertial and mass properties. Additional mass and inertial load will influence the dynamics behavior, especially stiffness information and vibration response of the whole ground test system. In this paper, a set of procedures are presented to remove the influence of air bearings and identify the true equivalent joint stiffness and damping from the test data of a motor-braked space manipulator with an air bearing support. First, inertia parameters are identified. Then, the equivalent joint stiffness and damping are determined by using a genetic algorithm (GA) method. Finally, true vibration characteristics of the manipulator are estimated by removing the additional inertia caused by the air bearings. Moreover, simulations and experiments are carried out to validate the presented procedures.
Language	English
Publishing date	2021-05-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2781824-X
ISSN	2296-9144 ; 2296-9144
ISSN (online)	2296-9144
ISSN	2296-9144
DOI	10.3389/frobt.2021.641165
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Article: Extracellular Vesicles Contribute to the Metabolism of Transthyretin Amyloid in Hereditary Transthyretin Amyloidosis.

Yamaguchi, Hiroki / Kawahara, Hironori / Kodera, Noriyuki / Kumaki, Ayanori / Tada, Yasutake / Tang, Zixin / Sakai, Kenji / Ono, Kenjiro / Yamada, Masahito / Hanayama, Rikinari

Frontiers in molecular biosciences

2022 Volume 9, Page(s) 839917

Abstract: Hereditary (variant) transthyretin amyloidosis (ATTRv amyloidosis), which is caused by variants in the transthyretin (TTR) gene, leads to TTR amyloid deposits in multiple organs and various symptoms such as limb ataxia, muscle weakness, and cardiac ... ...

Abstract	Hereditary (variant) transthyretin amyloidosis (ATTRv amyloidosis), which is caused by variants in the transthyretin (TTR) gene, leads to TTR amyloid deposits in multiple organs and various symptoms such as limb ataxia, muscle weakness, and cardiac failure. Interaction between amyloid proteins and extracellular vesicles (EVs), which are secreted by various cells, is known to promote the clearance of the proteins, but it is unclear whether EVs are involved in the formation and deposition of TTR amyloid in ATTRv amyloidosis. To clarify the relationship between ATTRv amyloidosis and EVs, serum-derived EVs were analyzed. In this study, we showed that cell-derived EVs are involved in the formation of TTR amyloid deposits on the membrane of small EVs, as well as the deposition of TTR amyloid in cells. Human serum-derived small EVs also altered the degree of aggregation and deposition of TTR. Furthermore, the amount of TTR aggregates in serum-derived small EVs in patients with ATTRv amyloidosis was lower than that in healthy controls. These results indicate that EVs contribute to the metabolism of TTR amyloid, and suggest that TTR in serum-derived small EVs is a potential target for future ATTRv amyloidosis diagnosis and therapy.
Language	English
Publishing date	2022-03-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2814330-9
ISSN	2296-889X
ISSN	2296-889X
DOI	10.3389/fmolb.2022.839917
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Article ; Online: Medical Applications and Advancement of Near Infrared Photosensitive Indocyanine Green Molecules.

Mahmut, Zulpya / Zhang, Chunmei / Ruan, Fei / Shi, Nan / Zhang, Xinyao / Wang, Yuda / Zheng, Xianhong / Tang, Zixin / Dong, Biao / Gao, Donghui / Sun, Jiao

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 16

Abstract: Indocyanine green (ICG) is an important kind of near infrared (NIR) photosensitive molecules for PTT/PDT therapy as well as imaging. When exposed to NIR light, ICG can produce reactive oxygen species (ROS), which can kill cancer cells and pathogenic ... ...

Abstract	Indocyanine green (ICG) is an important kind of near infrared (NIR) photosensitive molecules for PTT/PDT therapy as well as imaging. When exposed to NIR light, ICG can produce reactive oxygen species (ROS), which can kill cancer cells and pathogenic bacteria. Moreover, the absorbed light can also be converted into heat by ICG molecules to eliminate cancer cells. In addition, it performs exceptionally well in optical imaging-guided tumor therapy and antimicrobial therapy due to its deeper tissue penetration and low photobleaching properties in the near-infrared region compared to other dyes. In order to solve the problems of water and optical stability and multi-function problem of ICG molecules, composite nanomaterials based on ICG have been designed and widely used, especially in the fields of tumors and sterilization. So far, ICG molecules and their composite materials have become one of the most famous infrared sensitive materials. However, there have been no corresponding review articles focused on ICG molecules. In this review, the molecular structure and properties of ICG, composite material design, and near-infrared light- triggered anti-tumor, and antibacterial, and clinical applications are reviewed in detail, which of great significance for related research.
MeSH term(s)	Humans ; Indocyanine Green/pharmacology ; Dermatitis, Phototoxic ; Coloring Agents ; Anti-Bacterial Agents ; Hot Temperature
Chemical Substances	Indocyanine Green (IX6J1063HV) ; Coloring Agents ; Anti-Bacterial Agents
Language	English
Publishing date	2023-08-16
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28166085
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Article ; Online: Highly hydrostable and flexible opal photonic crystal film for enhanced up-conversion fluorescence sensor of COVID-19 antibody.

Hu, Songtao / Li, Yige / Dong, Biao / Tang, Zixin / Zhou, Bingshuai / Wang, Yue / Sun, Liheng / Xu, Lin / Wang, Lin / Zhang, Xueliang / Alifu, Nuernisha / Sun, Liankun / Song, Hongwei

Biosensors & bioelectronics

2023 Volume 237, Page(s) 115484

Abstract	Efficient detection of related markers is significant for the early screening of COVID-19. Near infrared (NIR) light excited up-conversion fluorescence probes are ideal for biosensing but limited by the low luminescence efficiency. In this work, a novel highly stable opal photonic crystal (OPC) structure was designed to provide an OPC effect for up-conversion fluorescence enhancement, and sensitive Novel Coronavirus IgG up-conversion FRET-based sensor was further constructed. For the problems of water stability and mechanical stability of polymer OPC which cannot be solved for a long time, polymer spray combined with a flipped OPC film strategy is presented. Fragmented size OPC film was firmly fixed by polymer modification layer, which gave large size OPC film great water stability, mechanical stability and bending performance without affecting the fluorescence enhancement property. On this basis, the up-conversion emission intensity was enhanced significantly, and fluorescence resonant energy transfer (FRET) based Novel Coronavirus IgG antibody sensor was constructed. Monolayer up-conversion nanoparticles (UCNPs) on the surface of the polydopamine (PDA)/OPC film can make the fluorescent signal more sensitive, and effectively reduce the detection limit. The test device integrating NIR excitation and mobile phone realized the visual fast detection, showing remarkable sensing performance for COVID-19 antibodies with the limit of detection (LOD) of 0.1 ng mL
MeSH term(s)	Humans ; COVID-19/diagnosis ; Biosensing Techniques ; Nanoparticles/chemistry ; Fluorescence Resonance Energy Transfer ; Polymers/chemistry
Chemical Substances	Polymers
Language	English
Publishing date	2023-06-16
Publishing country	England
Document type	Journal Article
ZDB-ID	1011023-9
ISSN	1873-4235 ; 0956-5663
ISSN (online)	1873-4235
ISSN	0956-5663
DOI	10.1016/j.bios.2023.115484
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Zs.A 2275: Show issues

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