Article ; Online: Changes of Tumor Markers in Patients with Lung Cancer after Immunotherapy and Their Link with Inflammation in the Body.
Computational and mathematical methods in medicine
2022 Volume 2022, Page(s) 7781686
Abstract: Purpose: To figure out tumor markers changes in lung cancer (LC) patients after immunotherapy and their link with inflammation in the body.: Methods: From May 2017 to January 2021, taking 97 LC patients with elevated Programmed Cell Death Protein 1 ... ...
| Abstract | Purpose: To figure out tumor markers changes in lung cancer (LC) patients after immunotherapy and their link with inflammation in the body. Methods: From May 2017 to January 2021, taking 97 LC patients with elevated Programmed Cell Death Protein 1 and Programmed Cell Death Protein-ligand 1 was as the research objects. They were all given immunotherapy and assigned into the remission and the nonremission groups on the grounds of the tumor remission after 6 months of treatment, after comparison of tumor markers [carcinoembryonic antigen (CEA), squamous cell carcinoma-associated antigen (SCC-Ag), cytokeratin 19 fragment (CYFRA12-1), and neuron-specific enolase (NSE)] and inflammation indicators [interleukin-10 (IL-10), interleukin (IL-6), and tumor necrosis factor- Results: Tumor markers, IL-10, IL-6, and TNF- Conclusion: Tumor markers and the inflammation state of the body in LC patients are memorably reduced after immunotherapy, and a correlation is presented between the two, which manifests evaluating value of the efficacy of immunotherapy. |
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| MeSH term(s) | Biomarkers, Tumor ; Humans ; Immunotherapy ; Inflammation ; Interleukin-10 ; Interleukin-6 ; Lung Neoplasms/metabolism ; Phosphopyruvate Hydratase ; Tumor Necrosis Factor-alpha |
| Chemical Substances | Biomarkers, Tumor ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Interleukin-10 (130068-27-8) ; Phosphopyruvate Hydratase (EC 4.2.1.11) |
| Language | English |
| Publishing date | 2022-07-19 |
| Publishing country | United States |
| Document type | Journal Article ; Retracted Publication |
| ZDB-ID | 2252430-7 |
| ISSN | 1748-6718 ; 1748-670X ; 1027-3662 |
| ISSN (online) | 1748-6718 |
| ISSN | 1748-670X ; 1027-3662 |
| DOI | 10.1155/2022/7781686 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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