LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 3 of total 3

Search options

  1. Article ; Online: Prophylactic Postoperative High Flow Nasal Oxygen Versus Conventional Oxygen Therapy in Obese Patients Undergoing Bariatric Surgery (OXYBAR Study): a Pilot Randomised Controlled Trial.

    Fulton, Rachel / Millar, Jonathan E / Merza, Megan / Johnston, Helen / Corley, Amanda / Faulke, Daniel / Rapchuk, Ivan L / Tarpey, Joe / Fanning, Jonathon P / Lockie, Philip / Lockie, Shirley / Fraser, John F

    Obesity surgery

    2021  Volume 31, Issue 11, Page(s) 4799–4807

    Abstract: Background: Patients with obesity are predisposed to a reduction in end-expiratory lung volume (EELV) and atelectasis after anaesthesia. High flow nasal oxygen (HFNO) may increase EELV, reducing the likelihood of postoperative pulmonary complications ( ... ...

    Abstract Background: Patients with obesity are predisposed to a reduction in end-expiratory lung volume (EELV) and atelectasis after anaesthesia. High flow nasal oxygen (HFNO) may increase EELV, reducing the likelihood of postoperative pulmonary complications (PPC). We conducted a pilot randomised controlled trial (RCT) of conventional oxygen therapy versus HFNO after bariatric surgery. The aim was to investigate the feasibility of using electrical impedance tomography (EIT) as a means of assessing respiratory mechanics and to inform the design of a definitive RCT.
    Methods: We performed a single-centre, parallel-group, pilot RCT. Adult patients with obesity undergoing elective bariatric surgery were eligible for inclusion. We excluded patients with a known contraindication to HFNO or with chronic lung disease.
    Results: Fifty patients were randomised in equal proportions. One patient crossed over from conventional O
    Conclusions: These data suggest that a large-scale RCT of HFNO after bariatric surgery in an 'all-comers' population is likely infeasible. While EIT was an effective means of assessing respiratory mechanics, it was impractical over time. Similarly, the infrequency of PPC precludes its use as a primary outcome. Future studies should focus on identifying patients at the greatest risk of PPC.
    MeSH term(s) Adult ; Bariatric Surgery ; Humans ; Obesity/complications ; Obesity/surgery ; Obesity, Morbid/surgery ; Oxygen ; Pilot Projects
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2021-08-13
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-021-05644-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: High flow nasal oxygen after bariatric surgery (OXYBAR), prophylactic post-operative high flow nasal oxygen versus conventional oxygen therapy in obese patients undergoing bariatric surgery: study protocol for a randomised controlled pilot trial.

    Fulton, Rachel / Millar, Jonathan E / Merza, Megan / Johnston, Helen / Corley, Amanda / Faulke, Daniel / Rapchuk, Ivan / Tarpey, Joe / Lockie, Philip / Lockie, Shirley / Fraser, John F

    Trials

    2018  Volume 19, Issue 1, Page(s) 402

    Abstract: Background: The incidence of obesity is increasing worldwide. In selected individuals, bariatric surgery may offer a means of achieving long-term weight loss, improved health, and healthcare cost reduction. Physiological changes that occur because of ... ...

    Abstract Background: The incidence of obesity is increasing worldwide. In selected individuals, bariatric surgery may offer a means of achieving long-term weight loss, improved health, and healthcare cost reduction. Physiological changes that occur because of obesity and general anaesthesia predispose to respiratory complications following bariatric surgery. The aim of this study is to determine whether post-operative high flow nasal oxygen therapy (HFNO
    Method: The OXYBAR study is a prospective, un-blinded, single centre, randomised, controlled pilot study. Patients with body mass index (BMI) > 30 kg/m
    Discussion: We hypothesise that the post-operative administration of HFNO
    Trial registration: Australian New Zealand Clinical Trials Registry (ANZCTR), ACTRN12617000694314 . Registered on 15 May 2017.
    MeSH term(s) Bariatric Surgery/adverse effects ; Bariatric Surgery/methods ; Cannula ; Humans ; Laparoscopy/adverse effects ; Lung/physiopathology ; Lung Diseases/diagnosis ; Lung Diseases/etiology ; Lung Diseases/physiopathology ; Lung Diseases/prevention & control ; Obesity/diagnosis ; Obesity/physiopathology ; Obesity/surgery ; Oxygen Inhalation Therapy/adverse effects ; Oxygen Inhalation Therapy/instrumentation ; Oxygen Inhalation Therapy/methods ; Pilot Projects ; Postoperative Care/adverse effects ; Postoperative Care/instrumentation ; Postoperative Care/methods ; Prospective Studies ; Queensland ; Randomized Controlled Trials as Topic ; Respiratory Function Tests ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2018-07-27
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1745-6215
    ISSN (online) 1745-6215
    ISSN 1468-6694 ; 1745-6215
    DOI 10.1186/s13063-018-2777-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Laryngeal nerve identification during thyroid surgery -- feasibility of a novel approach.

    Hillermann, Carl L / Tarpey, Joe / Phillips, David E

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2003  Volume 50, Issue 2, Page(s) 189–192

    Abstract: Purpose: Recurrent laryngeal nerve damage remains one of the most devastating complications of thyroid surgery. However, nerve identification is not always easy, and a reliable method to locate nerves intraoperatively is needed.: Methods: Thirty ... ...

    Abstract Purpose: Recurrent laryngeal nerve damage remains one of the most devastating complications of thyroid surgery. However, nerve identification is not always easy, and a reliable method to locate nerves intraoperatively is needed.
    Methods: Thirty consecutive patients were anesthetized for elective thyroid surgery using a standard technique. Indications for surgery covered a broad spectrum of conditions. In the technique described, the airway is secured with a micro laryngeal tube, and a laryngeal mask airway is inserted through which a fibreoptic scope is inserted to view the larynx. Movement of the arytenoids in response to nerve stimulation can be viewed at any time on a television monitor. The airway is secure throughout the procedure and nerve identification is continuously available.
    Results: In our study 30 patients were anesthetized and nerve stimulation used in all of them to identify both superior and recurrent laryngeal nerve. None of them developed intraoperative complications. One patient had temporary postoperative recurrent laryngeal nerve damage, which was not attributable to use of this method.
    Conclusion: On the basis of our results so far, the method described is feasible and provides a safe method of nerve location during surgery. Laryngeal nerve stimulation is likely to become an integral part of thyroid surgery.
    MeSH term(s) Adult ; Aged ; Anesthesia ; Arytenoid Cartilage/anatomy & histology ; Electric Stimulation ; Female ; Fiber Optic Technology ; Humans ; Intubation, Intratracheal ; Laryngeal Masks ; Laryngeal Nerve Injuries ; Laryngeal Nerves/anatomy & histology ; Laryngoscopes ; Laryngoscopy ; Male ; Middle Aged ; Monitoring, Intraoperative ; Postoperative Complications/prevention & control ; Thyroid Gland/surgery ; Thyroidectomy/methods
    Language English
    Publishing date 2003-02
    Publishing country United States
    Document type Clinical Trial ; Journal Article
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/BF03017855
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top