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  1. Article ; Online: Author response.

    Taylor, Clare J

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2023  Volume 73, Issue 727, Page(s) 58

    Language English
    Publishing date 2023-01-26
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp23X731829
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  2. Article ; Online: Earlier heart failure diagnosis in primary care.

    Taylor, Clare J

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2022  Volume 73, Issue 726, Page(s) 4–5

    MeSH term(s) Humans ; Heart Failure/diagnosis ; Early Diagnosis ; Primary Health Care
    Language English
    Publishing date 2022-12-21
    Publishing country England
    Document type Editorial
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp23X731481
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Diagnosing heart failure: challenges in primary care.

    Taylor, Clare J

    Heart (British Cardiac Society)

    2019  Volume 105, Issue 9, Page(s) 663–664

    MeSH term(s) Heart Failure ; Humans ; Primary Health Care
    Language English
    Publishing date 2019-01-15
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2018-314396
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  4. Article ; Online: Exacerbating the burden of cardiovascular disease: how can we address cardiopulmonary risk in individuals with chronic obstructive pulmonary disease?

    Shrikrishna, Dinesh / Taylor, Clare J / Stonham, Carol / Gale, Chris P

    European heart journal

    2023  Volume 45, Issue 4, Page(s) 247–249

    MeSH term(s) Humans ; Cardiovascular Diseases/prevention & control ; Pulmonary Disease, Chronic Obstructive/complications ; Heart
    Language English
    Publishing date 2023-10-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad669
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  5. Article ; Online: Long term changes in health-related quality of life for people with heart failure: the ECHOES study.

    Roalfe, Andrea K / Taylor, Clare J / Hobbs, F D Richard

    ESC heart failure

    2022  Volume 10, Issue 1, Page(s) 211–222

    Abstract: Aims: Heart failure (HF) impairs all aspects of health-related quality of life (HRQoL), but little is known about the effect of developing HF on HRQoL over time. We aimed to report changes in HRQoL over a 13-year period.: Methods and results: HRQoL ... ...

    Abstract Aims: Heart failure (HF) impairs all aspects of health-related quality of life (HRQoL), but little is known about the effect of developing HF on HRQoL over time. We aimed to report changes in HRQoL over a 13-year period.
    Methods and results: HRQoL was measured in the Echocardiographic Heart of England Screening (ECHOES) study and the ECHOES-X follow-up study (N = 1618) using the SF-36 questionnaire (Version 1). Mixed modelling compared changes in HRQoL across diagnostic groups, adjusting for potential predictors and design variables. Patients who had developed HF with reduced ejection fraction (HFrEF) or HF with preserved ejection fraction (HFpEF) at rescreening had significantly greater reduction in physical functioning (PF) and role physical (RP) scores compared with those without HF; adjusted mean difference in PF: HFrEF -16.1, [95% confidence interval (CI) -22.2 to -10.1]; HFpEF -14.6, (95% CI -21.2 to -8.1); in RP: HFrEF -20.7, (95% CI -31.8 to -9.7); HFpEF -19.3, (95% CI -31.0 to -7.6). Changes in HRQoL of those with a HF diagnosis at baseline and rescreen, with exception of role emotion, were similar to those without HF but started from a much lower baseline score.
    Conclusions: People with a new diagnosis of HF at rescreening had a significant reduction in HRQoL. Conversely, for those with HF detected on initial screening, little change was observed in HRQoL scores on rescreening. Further research is required to understand the development of HF over time and to test interventions designed to prevent decline in HRQoL, potentially through earlier diagnosis and treatment optimization.
    MeSH term(s) Humans ; Heart Failure/therapy ; Quality of Life ; Follow-Up Studies ; Stroke Volume ; Echocardiography
    Language English
    Publishing date 2022-10-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2814355-3
    ISSN 2055-5822 ; 2055-5822
    ISSN (online) 2055-5822
    ISSN 2055-5822
    DOI 10.1002/ehf2.14182
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  6. Article ; Online: FASTer diagnosis: Time to BEAT heart failure.

    Taylor, Clare J / Hartshorne-Evans, Nick / Satchithananda, Duwarakan / Hobbs, Fd Richard

    BJGP open

    2021  Volume 5, Issue 3

    Language English
    Publishing date 2021-06-30
    Publishing country England
    Document type Journal Article
    ISSN 2398-3795
    ISSN (online) 2398-3795
    DOI 10.3399/BJGPO.2021.0006
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  7. Article ; Online: Body mass index and survival in people with heart failure.

    Jones, Nicholas R / Ordóñez-Mena, José M / Roalfe, Andrea K / Taylor, Kathryn S / Goyder, Clare R / Hobbs, Fd Richard / Taylor, Clare J

    Heart (British Cardiac Society)

    2023  Volume 109, Issue 20, Page(s) 1542–1549

    Abstract: Aims: In people with heart failure (HF), a high body mass index (BMI) has been linked with better outcomes ('obesity paradox'), but there is limited evidence in community populations across long-term follow-up. We aimed to examine the association ... ...

    Abstract Aims: In people with heart failure (HF), a high body mass index (BMI) has been linked with better outcomes ('obesity paradox'), but there is limited evidence in community populations across long-term follow-up. We aimed to examine the association between BMI and long-term survival in patients with HF in a large primary care cohort.
    Methods: We included patients with incident HF aged ≥45 years from the Clinical Practice Research Datalink (2000-2017). We used Kaplan-Meier curves, Cox regression and penalised spline methods to assess the association of pre-diagnostic BMI, based on WHO classification, with all-cause mortality.
    Results: There were 47 531 participants with HF (median age 78.0 years (IQR 70-84), 45.8% female, 79.0% white ethnicity, median BMI 27.1 (IQR 23.9-31.0)) and 25 013 (52.6%) died during follow-up. Compared with healthy weight, people with overweight (HR 0.78, 95% CI 0.75 to 0.81, risk difference (RD) -4.1%), obesity class I (HR 0.76, 95% CI 0.73 to 0.80, RD -4.5%) and class II (HR 0.76, 95% CI 0.71 to 0.81, RD -4.5%) were at decreased risk of death, whereas people with underweight were at increased risk (HR 1.59, 95% CI 1.45 to 1.75, RD 11.2%). In those underweight, this risk was greater among men than women (p value for interaction=0.02). Class III obesity was associated with increased risk of all-cause mortality compared with overweight (HR 1.23, 95% CI 1.17 to 1.29).
    Conclusion: The U-shaped relationship between BMI and long-term all-cause mortality suggests a personalised approach to identifying optimal weight may be needed for patients with HF in primary care. Underweight people have the poorest prognosis and should be recognised as high-risk.
    MeSH term(s) Male ; Humans ; Female ; Aged ; Overweight/complications ; Body Mass Index ; Thinness/complications ; Thinness/epidemiology ; Heart Failure ; Obesity/complications ; Obesity/epidemiology ; Obesity/diagnosis ; Risk Factors
    Language English
    Publishing date 2023-09-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2023-322459
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  8. Article ; Online: Diagnosis and management of chronic heart failure: NICE guideline update 2018.

    Taylor, Clare J / Moore, Jim / O'Flynn, Norma

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2019  Volume 69, Issue 682, Page(s) 265–266

    MeSH term(s) General Practice/methods ; General Practice/standards ; Heart Failure/diagnosis ; Heart Failure/therapy ; Humans ; Patient Care Management/methods ; Patient Care Management/standards ; Severity of Illness Index ; State Medicine ; United Kingdom
    Language English
    Publishing date 2019-04-25
    Publishing country England
    Document type Journal Article ; Practice Guideline
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp19X702665
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  9. Article: Multiprofessional heart failure self-development framework.

    Forsyth, Paul / Young, Susan / Hughes, Kirsty / James, Ruby / Oxley, Cheryl / Kelly, Ruth / Jones, Rebecca / Briggs, Sarah / Mackay-Thomas, Lynn / Millerick, Yvonne / Simpson, Maggie / Taylor, Clare J / Beggs, Simon / Piper, Susan / Duckett, Simon

    Open heart

    2024  Volume 11, Issue 1

    Abstract: Objective: Heart failure remains a key public health priority across the globe. The median age of people with heart failure admitted to hospital in the UK is 81 years old. Many such patients transcend the standard interventions that are well ... ...

    Abstract Objective: Heart failure remains a key public health priority across the globe. The median age of people with heart failure admitted to hospital in the UK is 81 years old. Many such patients transcend the standard interventions that are well characterised and evidenced in guidelines, into holistic aspects surrounding frailty, rehabilitation and social care. Previous published competency frameworks in heart failure have focused on the value of doctors, nurses and pharmacists. We aimed to provide an expert consensus on the minimum heart failure-specific competencies necessary for multiple different healthcare professionals, including physiotherapists, occupational therapists, dietitians and cardiac physiologists.
    Methods: The document has been developed focussing on four main parts, (1) establishing a project working group of expert professionals, (2) a literature review of previously existing published curricula and competency frameworks, (3) consensus building, which included developing a structure to the framework with ongoing review of the contents to adapt and be inclusive for each specialty and (4) write up and dissemination to widen the impact of the project.
    Results: The final competency framework displays competencies across seven sections; knowledge (including subheadings on heart failure syndrome, diagnosis and clinical management); general skills; heart failure-specific skills; clinical autonomy; multidisciplinary team working; teaching and education; and research and development.
    Conclusion: People with heart failure can be complex and have needs that require input from a broad range of specialties. This publication focuses on the vital impact of wider multidisciplinary groups and should help define the generic core heart failure-specific competencies needed to support future pipelines of professionals, who regularly interact with and deliver care for patients with heart failure.
    MeSH term(s) Humans ; Aged, 80 and over ; Health Personnel/education ; Curriculum ; Heart Failure/diagnosis ; Heart Failure/therapy
    Language English
    Publishing date 2024-01-19
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 2747269-3
    ISSN 2053-3624
    ISSN 2053-3624
    DOI 10.1136/openhrt-2023-002554
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  10. Article ; Online: Understanding parents' decision-making on participation in clinical trials in children's heart surgery: a qualitative study.

    Drury, Nigel E / Menzies, Julie C / Taylor, Clare J / Jones, Timothy J / Lavis, Anna C

    BMJ open

    2021  Volume 11, Issue 2, Page(s) e044896

    Abstract: Objectives: Few children undergoing heart surgery are recruited to clinical trials and little is known about the views and attitudes of parents towards trials. This study explored parents' perspectives on decision-making about their child's ... ...

    Abstract Objectives: Few children undergoing heart surgery are recruited to clinical trials and little is known about the views and attitudes of parents towards trials. This study explored parents' perspectives on decision-making about their child's participation in a clinical trial during their elective cardiac surgery.
    Design: Qualitative interview study.
    Setting: Single-centre substudy of a multicentre, double-blind, randomised controlled trial to investigate the effects of remote ischaemic preconditioning in children undergoing cardiac surgery.
    Participants: Parents of children approached to participate in the trial, both consenters and decliners.
    Methods: Semistructured interviews were conducted face-to-face or by telephone following discharge, digitally audio-recorded, transcribed and thematically analysed.
    Results: Of 46 patients approached for the trial, 24 consenting and 2 declining parents agreed to participate in an interview (21 mothers, 5 fathers). Parental decision-making about research was influenced by (1) potential risks or additional procedures; (2) personal benefit and altruism for the 'cardiac community'; (3) information, preparation, timing and approach; and (4) trust in the clinical team and collaboration with researchers. All of these were placed within the context of their understanding of the trial and knowledge of research.
    Conclusions: Parents of children undergoing cardiac surgery attach value to clinical research and are supportive of clinical trials when there is no or minimal perceived additional risk. These findings enhance our understanding of the factors that influence parents' decision-making and should be used to inform the design and conduct of future paediatric surgical trials.
    Trial registration number: ISRCTN12923441; Pre-results.
    MeSH term(s) Cardiac Surgical Procedures ; Child ; Comprehension ; Decision Making ; Double-Blind Method ; Humans ; Parents ; Qualitative Research ; Trust
    Language English
    Publishing date 2021-02-23
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2020-044896
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