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  1. Article ; Online: Genetic Mapping and Phenotypic Analysis of

    Thomson, Lauren / Shah, Hemin P / Akinwotu Adewale, Victoria / Beise, Alyssa / Bliayang, Camryn / Cioch, Zuzanna / Craig, Mason / Crump, Adell / Durdan, Maya / Espinosa, Madeleine / Feda, Kaitlin / Feist, Jami / Fragoso, Alexis / Haro, Genesys / Hoffman, Breanna / Horne, Paige / Houha, Nathan / Hounnou, Shirley / Inman, Annabel /
    Jakobsze, Daniel / Juarez-Morales, Yolanda / Khan, Yousuf / Kohler, Joshua / Lawlor, Reece / Lieser, Bethany / Loitz, Ryan / Martinez, Erik / Martinez, Alexis / Martinez, Michelle / Maza, Brandyn / Mendoza, Brenda / Miller, Steven / Mngodo, Haniel / O'Shea, Sarah / Piane, Sarah N / Raivala, Ethan / Ruger, Sophie / Singer, Abigail / Strand, Jessica E / Traylor, Alexis / Wright, Asia / McCabe, Shawn / Pandit, Sandesh S / Bieser, Kayla / Croonquist, Paula / Taylor, Elizabeth E / Wittke-Thompson, Jacqueline / Kagey, Jacob D / Devergne, Olivier

    microPublication biology

    2024  Volume 2024

    Abstract: Genetic screens are valuable for identifying novel genes involved in the regulation of developmental processes. To identify genes associated with cell growth regulation ... ...

    Abstract Genetic screens are valuable for identifying novel genes involved in the regulation of developmental processes. To identify genes associated with cell growth regulation in
    Language English
    Publishing date 2024-04-13
    Publishing country United States
    Document type Journal Article
    ISSN 2578-9430
    ISSN (online) 2578-9430
    DOI 10.17912/micropub.biology.001019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration.

    Sahoo, Pabitra K / Lee, Seung Joon / Jaiswal, Poonam B / Alber, Stefanie / Kar, Amar N / Miller-Randolph, Sharmina / Taylor, Elizabeth E / Smith, Terika / Singh, Bhagat / Ho, Tammy Szu-Yu / Urisman, Anatoly / Chand, Shreya / Pena, Edsel A / Burlingame, Alma L / Woolf, Clifford J / Fainzilber, Mike / English, Arthur W / Twiss, Jeffery L

    Nature communications

    2018  Volume 9, Issue 1, Page(s) 3358

    Abstract: Critical functions of intra-axonally synthesized proteins are thought to depend on regulated recruitment of mRNA from storage depots in axons. Here we show that axotomy of mammalian neurons induces translation of stored axonal mRNAs via regulation of the ...

    Abstract Critical functions of intra-axonally synthesized proteins are thought to depend on regulated recruitment of mRNA from storage depots in axons. Here we show that axotomy of mammalian neurons induces translation of stored axonal mRNAs via regulation of the stress granule protein G3BP1, to support regeneration of peripheral nerves. G3BP1 aggregates within peripheral nerve axons in stress granule-like structures that decrease during regeneration, with a commensurate increase in phosphorylated G3BP1. Colocalization of G3BP1 with axonal mRNAs is also correlated with the growth state of the neuron. Disrupting G3BP functions by overexpressing a dominant-negative protein activates intra-axonal mRNA translation, increases axon growth in cultured neurons, disassembles axonal stress granule-like structures, and accelerates rat nerve regeneration in vivo.
    MeSH term(s) Animals ; Axons/metabolism ; Cells, Cultured ; Cytoplasmic Granules/metabolism ; Female ; Fluorescence Recovery After Photobleaching ; HEK293 Cells ; Humans ; Male ; Mice ; Microscopy, Fluorescence ; NIH 3T3 Cells ; Nerve Regeneration/genetics ; Nerve Regeneration/physiology ; Poly-ADP-Ribose Binding Proteins/genetics ; Poly-ADP-Ribose Binding Proteins/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley
    Chemical Substances Poly-ADP-Ribose Binding Proteins ; RNA, Messenger
    Language English
    Publishing date 2018-08-22
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-018-05647-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: clifford

    Nowaskie, Reagan R / Kitch, Ashley / Adams, Abby / Anandaraj, Abinaya / Apawan, Ethan / Bañuelos, Liliana / Betz, Cassandra J / Bogunia, Julia M / Buechlein, Nicholas / Burns, Morgan R / Collier, Hayley A / Collins, Zach / Combs, Kynzie / Dakarian, Vana D / Daniel, Abigail / De Jesus Iii, Conrad M / Erickson, John D / Estrada, Bianca / Estrada, Kevin /
    Fields, Sydney / Gabriel, Maya / Garcia, Rosario M / Gitamo, Sylvia / Granath, Emma / Hardin, Sabrina N / Hattling, Emily / Henriquez, Alexandra Vl / Hernandez, Destiny / Johnson, Luke / Kim, Annie H / Kolley, Lillian K / Larue, Katelynn M / Lockwood, Erin / Longoria, Nelia / Lopez, Cassandra / Lopez-Roca Fernandez, Rosario C / Lozano, Sofia / Manthie, Carissa / May, Trinity / Mehrzad, Zorah / Mendoza, Itzel / Mohan, Somya / Mounthachak, Claylan / Muyizere, Merveille / Myers, Margaret R / Newton, Jayce / Nwawueze, Amarachi / Paredes, Ariana J / Pezdek, Marissa N / Phat Nguyen, Hoang / Pobuda, Nadia / Sadat, Sahar / Sailor, Johnathon J / Santiago, David / Sbarbaro, Madison / Schultz Iii, David E / Senobari, Anahita N / Shouse, Emma M / Snarski, Sarah M / Solano, Estefanie / Solis Campos, Naomi / Stewart, Elnora / Szczepaniak, Jessica / Tejeda, Michael / Teoli, Dominic F / Tran, Michael / Trivedi, Nishita / Uribe Aristizabal, Laurita / Vargas, Bryan Z / Walker Iii, Kenneth W / Wasiqi, Joseph / Wong, Joyi / Zachrel, Adira / Shah, Hemin P / Small, Elizabeth / Watts, Charlie T / Croonquist, Paula / Devergne, Olivier / Jones, Amy K / Taylor, Elizabeth E / Kagey, Jacob D / Merkle, Julie A

    microPublication biology

    2023  Volume 2023

    Abstract: ... ...

    Abstract Mutant
    Language English
    Publishing date 2023-08-22
    Publishing country United States
    Document type Journal Article
    ISSN 2578-9430
    ISSN (online) 2578-9430
    DOI 10.17912/micropub.biology.000936
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Adaptive visual metamorphosis in a deep-sea hydrothermal vent crab.

    Jinks, Robert N / Markley, Tara L / Taylor, Elizabeth E / Perovich, Gina / Dittel, Ana I / Epifanio, Charles E / Cronin, Thomas W

    Nature

    2002  Volume 420, Issue 6911, Page(s) 68–70

    Abstract: Hydrothermal vents along the mid-ocean ridges host ephemeral ecosystems of diverse endemic fauna including several crustacean species, some of which undergo planktonic development as larvae up to 1,000 m above and 100 km away from the vents. Little is ... ...

    Abstract Hydrothermal vents along the mid-ocean ridges host ephemeral ecosystems of diverse endemic fauna including several crustacean species, some of which undergo planktonic development as larvae up to 1,000 m above and 100 km away from the vents. Little is known about the role of vision in the life history of vent fauna. Here we report that planktonic zoea larvae of the vent crab Bythograea thermydron possess image-forming compound eyes with a visual pigment sensitive to the blue light of mesopelagic waters. As they metamorphose and begin to descend to and settle at the vents, they lose their image-forming optics and develop high-sensitivity naked-retina eyes. The spectral absorbance of the visual pigment in these eyes shifts towards longer wavelengths from larva to postlarva to adult. This progressive visual metamorphosis trades imaging for increased sensitivity, and changes spectral sensitivity from the blue wavelengths of the larval environment towards the dim, longer wavelengths produced in the deeper bathypelagic vent environment of the adults. As hydrothermal vents produce light, vision may supplement thermal and chemical senses to orient postlarval settlement at vent sites.
    MeSH term(s) Adaptation, Physiological ; Animals ; Brachyura/anatomy & histology ; Brachyura/growth & development ; Brachyura/physiology ; Environment ; Eye/anatomy & histology ; Eye/chemistry ; Eye/growth & development ; Hot Temperature ; Larva/anatomy & histology ; Larva/growth & development ; Larva/physiology ; Light ; Metamorphosis, Biological ; Oceans and Seas ; Ocular Physiological Phenomena ; Plankton/physiology ; Retinal Pigments/analysis ; Steam ; Vision, Ocular/physiology
    Chemical Substances Retinal Pigments ; Steam
    Language English
    Publishing date 2002-11-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/nature01144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Online: Genetic mapping of

    Mast, Elizabeth / Bieser, Kayla L / Abraham-Villa, Mary / Adams, Vanessa / Akinlehin, Akinwonuola J / Aquino, Lynarose Z / Austin, Joseph L / Austin, Abigail K / Beckham, Carissa N / Bengson, Ethan J / Bieszk, Amanda / Bogard, Brianna L / Brennan, Rowan C / Brnot, Rebecca M / Cirone, Nicholas J / Clark, Mason R / Cooper, Brianna N / Cruz, Dennys / Daprizio, Katlyn A /
    DeBoe, Jason / Dencker, Michaela M / Donnelly, Laura L / Driscoll, Leanne / DuBeau, Ryan J / Durso, Sirada W / Ejub, Adam / Elgosbi, Waad / Estrada, Melanie / Evins, Kaeli / Fox, Pearl D / France, Jacob M / Franco Hernandez, Maira G / Garcia, Lizbeth A / Garl, Olivia / Gorsuch, Myeerah R / Gorzeman-Mohr, Mikayla A / Grothouse, Madison E / Gubbels, Megan E / Hakemiamjad, Romina / Harvey, Chloé V / Hoeppner, Madeline A / Ivanov, Jessica L / Johnson, Veronica M / Johnson, Jessica L / Johnson, Ashton / Johnston, Kaleigh / Keller, Katie R / Kennedy, Breanna T / Killian, Levi R / Klumb, Marissa / Koehn, Olivia L / Koym, Aaron S / Kress, Kari J / Landis, Regan E / Lewis, Kaitlyn N / Lim, Enosh / Lopez, Ilcen K / Lowe, D'Artagnan / Luengo Carretero, Paula / Lunaburg, Grace / Mallinder, Samantha L / Marshall, Natalie A / Mathew, Jessica / Mathew, Jasmine / Mcmanaway, Hailee S / Meegan, Emily N / Meyst, Jacob D / Miller, Meredith J / Minogue, Colin K / Mohr, Alina A / Moran, Cristhian I / Moran, Adrian / Morris, Morgan D / Morrison, Michael D / Moses, Emmily A / Mullins, Cade J / Neri, Citlalli I / Nichols, Jess M / Nickels, Breanna R / Okai, Akosua M / Okonmah, Chiedu / Paramo, Makena / Paramo, Meagan / Parker, Sydney L / Parmar, Neil K / Paschal, Jacob / Patel, Prem / Patel, Deep / Perkins, Erica B / Perry, Madelyn M / Perry, Zachary / Pollock, Amanda A / Portalatin, Oxxyris / Proffitt, Kamron S / Queen, Jason T / Quemeneur, Alexis C / Richardson, Amelia G / Rosenberger, Kaylee / Rutherford, Allison M / Santos-Perez, Itchel X / Sarti, Christy Y / Schouweiler, Lacey J / Sessing, Lauren M / Setaro, Sara O / Silvestri, Christopher F / Smith, Olivia A / Smith, Mackenzie J / Sumner, Jayson C / Sutton, Rachel R / Sweckard, Lindsay / Talbott, Nicholas B / Traxler, Peyton A / Truesdell, Jenna / Valenti, Aaron F / Verace, Leif / Vijayakumar, Pragathi / Wadley, William L / Walter, Katherine E / Williams, Ayanna R / Wilson, Trey J / Witbeck, Makayla A / Wobler, Trinity M / Wright, Lucas J / Zuczkowska, Karolina A / Devergne, Olivier / Hamill, Danielle R / Shah, Hemin P / Siders, Jamie / Taylor, Elizabeth E / Vrailas-Mortimer, Alysia D / Kagey, Jacob D

    microPublication biology

    2022  Volume 2022

    Language English
    Publishing date 2022-03-18
    Publishing country United States
    Document type Journal Article
    ISSN 2578-9430
    ISSN (online) 2578-9430
    DOI 10.17912/micropub.biology.000542
    Database MEDical Literature Analysis and Retrieval System OnLINE

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