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  1. AU="Taylor, Evangeline"
  2. AU="Thomas E Morrison"
  3. AU="Hernandez-Cuebas, Lisa"
  4. AU="Juliann E Aukema"
  5. AU="Guy Melamed"
  6. AU="Raikhel, Marina"
  7. AU="Bhatti, Hakikat Bir Singh"
  8. AU="Christian Molnár"
  9. AU="Montarello, Natalie"
  10. AU="Phan Nu Dieu Hong"
  11. AU="Polliack, Michael"
  12. AU="Ye, Tianai"
  13. AU="Galenson, Walter"
  14. AU="Nisar, Muhammad K"
  15. AU="Keshavarzi, Nahid"
  16. AU="Gabig, Theodore G"
  17. AU="Nixon, Ian J"
  18. AU="Huang Xiaoting"
  19. AU="Colturato, Virgílio Antônio Rensi"
  20. AU="Mahfouz, Amira Y"
  21. AU="Ayyappan, Sabarish"
  22. AU=Wang Kevin L-C
  23. AU="Lukas T. Hirschwald"
  24. AU="Morley-Davies, A"
  25. AU="Felsberg, Gary J"
  26. AU="Bogen, Oliver"
  27. AU="de Portu, Simona"
  28. AU="Janssens, Rick"

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  1. Artikel: "I'm in pain and I want help": An online survey investigating the experiences of tic-related pain and use of pain management techniques in people with tics and tic disorders.

    Taylor, Evangeline / Anderson, Seonaid / Davies, E Bethan

    Frontiers in psychiatry

    2022  Band 13, Seite(n) 914044

    Abstract: Objectives: Tic disorders (TDs) are complex neurological conditions characterized by involuntary, persistent vocalizations and motor movements called tics. Tics involve brief muscle movements and can impair many aspects of daily functioning and quality ... ...

    Abstract Objectives: Tic disorders (TDs) are complex neurological conditions characterized by involuntary, persistent vocalizations and motor movements called tics. Tics involve brief muscle movements and can impair many aspects of daily functioning and quality of life in patients - and their physical nature can cause pain. Understanding individuals' experiences of tic-related pain and pain management could help explore this under-researched area and identify additional support needs for this population. The aim of this study was to investigate experiences of pain and use of pain management techniques in people with tic disorders.
    Methods: An online survey consisting of multiple choice and open-ended questions exploring experiences of tic-related pain, help-seeking behavior for tic-related pain, and use of pain relief techniques for tic-related pain, was circulated online
    Results: One hundred eighty-one participants (16-71 years; 58.0% female) from 18 countries completed the online survey. Several aspects of tics were associated with pain, including the physical effort of motor tics (
    Conclusions: Tic-related pain was reported to have a significant physical and psychological impact which impacted aspects of daily living in people with tic disorders. The findings add to limited research suggesting tic-related pain is a dominant issue for individuals with tic disorders, potentially impacting upon their quality of life. Increased understanding of tic-related pain and its influence may be helpful in the long-term management of tic disorders, both in terms of clinical management and patients' self-management.
    Sprache Englisch
    Erscheinungsdatum 2022-08-05
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2022.914044
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Communal coping and glycemic control: Daily patterns among young adult couples with type 1 diabetes.

    Yorgason, Jeremy B / Noorda, Naomi M / Steeger, Danielle / Saylor, Jennifer / Berg, Cynthia / Davey, Adam / Rellaford, Susannah / Kirkham, Daylee / Saunders, James / Taylor, Evangeline

    Families, systems & health : the journal of collaborative family healthcare

    2023  

    Abstract: Introduction: Young adulthood is a time when persons with Type 1 diabetes (T1D) become more fully responsible for diabetes management. Establishing healthy diabetes routines during this period is foundational for successful management across adulthood. ... ...

    Abstract Introduction: Young adulthood is a time when persons with Type 1 diabetes (T1D) become more fully responsible for diabetes management. Establishing healthy diabetes routines during this period is foundational for successful management across adulthood. Although partner support is generally considered helpful in T1D management, less is known about specific partner behaviors that could benefit glucose levels. The aim of this study was to explore associations between communal coping behaviors and T1D glucose management.
    Method: During 2018-2020, 23 young married opposite-sex couples (
    Results: Multilevel model results suggested that higher time-in-range on a given day was predicted by reports of lower daily spousal instrumental support, lower overprotective and controlling behaviors, and by higher emotional support. Controlling spousal behavior on one day was associated with higher time-in-range the next day. At the same time, patient reports of higher average spousal controlling behavior (across all days) were associated with lower time-in-range and higher average glucose. Average glucose was also predicted by communal coping behaviors (especially within-person higher instrumental support), yet results were less robust after covariates were considered.
    Discussion: Some young romantic partners may engage in behaviors that are associated with higher average blood glucose and lower time-in-range for the person with T1D. Persons with T1D could communicate to their partners types of support that are helpful versus not. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
    Sprache Englisch
    Erscheinungsdatum 2023-11-13
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1326859-4
    ISSN 1939-0602 ; 1091-7527 ; 0736-1718
    ISSN (online) 1939-0602
    ISSN 1091-7527 ; 0736-1718
    DOI 10.1037/fsh0000857
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Hypermethylated genes as biomarkers of cancer in women with pathologic nipple discharge.

    Fackler, Mary Jo / Rivers, Aeisha / Teo, Wei Wen / Mangat, Amrit / Taylor, Evangeline / Zhang, Zhe / Goodman, Steve / Argani, Pedram / Nayar, Ritu / Susnik, Barbara / Sukumar, Saraswati / Khan, Seema A

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2009  Band 15, Heft 11, Seite(n) 3802–3811

    Abstract: Purpose: In a pilot study of women with pathologic nipple discharge (PND) undergoing ductoscopy, we tested quantitative assessment of gene promoter hypermethylation using quantitative multiplex methylation-specific PCR (QM-MSP) to enhance detection of ... ...

    Abstract Purpose: In a pilot study of women with pathologic nipple discharge (PND) undergoing ductoscopy, we tested quantitative assessment of gene promoter hypermethylation using quantitative multiplex methylation-specific PCR (QM-MSP) to enhance detection of duct carcinoma in situ (DCIS).
    Experimental design: Women with PND underwent ductoscopy; ducts with significant lesions were surgically resected (36 ducts in 33 women) and those with minimal findings were not (28 ducts in 16 women). QM-MSP was done on ductoscopy cell samples. Results were compared with cytology and tissue histology.
    Results: Cells from ducts with significant lesions on ductoscopy had significantly higher levels of methylation than those with minimal findings. Furthermore, cells from ducts with DCIS displayed higher levels of methylation than those with benign lesions such as papilloma (P = 0.006); or ducts with minimal findings on ductoscopy (P = 0.0001). Cumulative RASSF1A, TWIST1, and HIN1 gene methylation accurately distinguished ducts with cancerous versus benign lesions (100% sensitivity, 72% specificity, and area under the curve of 0.91 according to receiving operating characteristic analyses). QM-MSP analysis was more informative than cytology (100% versus 29% sensitivity, respectively), for detecting DCIS. In a validation set of paraffin-embedded DCIS and papilloma samples from women presenting with PND, QM-MSP was significantly higher in DNA from DCIS than papilloma sections (P = 0.002).
    Conclusion: The positive predictive value of ductoscopy was more than doubled (19% versus 47%) with the addition of QM-MSP, demonstrating the benefit of targeting ducts having both high methylation and significant abnormalities on ductoscopy for surgical excision. Future large-scale studies to validate this approach are needed.
    Mesh-Begriff(e) Adult ; Aged ; Biomarkers, Tumor/genetics ; Breast Diseases/diagnosis ; Breast Diseases/genetics ; Breast Neoplasms/diagnosis ; Breast Neoplasms/genetics ; Carcinoma in Situ/diagnosis ; Carcinoma in Situ/genetics ; Carcinoma, Ductal, Breast/diagnosis ; Carcinoma, Ductal, Breast/genetics ; Cytokines/genetics ; DNA Methylation ; Diagnosis, Differential ; Endoscopy/methods ; Female ; Genetic Predisposition to Disease/genetics ; Humans ; Mammary Glands, Human/metabolism ; Mammary Glands, Human/pathology ; Middle Aged ; Nipples/metabolism ; Nipples/pathology ; Nuclear Proteins/genetics ; Polymerase Chain Reaction/methods ; Reproducibility of Results ; Sensitivity and Specificity ; Tumor Suppressor Proteins/genetics ; Twist-Related Protein 1/genetics
    Chemische Substanzen Biomarkers, Tumor ; Cytokines ; Nuclear Proteins ; RASSF1 protein, human ; SCGB3A1 protein, human ; TWIST1 protein, human ; Tumor Suppressor Proteins ; Twist-Related Protein 1
    Sprache Englisch
    Erscheinungsdatum 2009-05-26
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-08-1981
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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