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  1. AU="Taylor, Marisa"
  2. AU="Shanto, Hasibul Hasan"
  3. AU="Ahmad Khanshour"

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  1. Artikel ; Online: A Curious Case of a Pigmented Lesion.

    Sachedina, Dilshad / Taylor, Marisa

    Indian journal of dermatology

    2024  Band 69, Heft 1, Seite(n) 104–105

    Sprache Englisch
    Erscheinungsdatum 2024-02-27
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 416069-1
    ISSN 1998-3611 ; 0019-5154
    ISSN (online) 1998-3611
    ISSN 0019-5154
    DOI 10.4103/ijd.ijd_281_23
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Cathepsin-C mutation in an individual with phenotypic features of Haim-Munk syndrome: a case report.

    McCarthy, Rebecca L / Gnanappiragasam, Dushyanth / Scorer, Matthew / Taylor, Marisa / O'Toole, Edel A

    Clinical and experimental dermatology

    2023  Band 48, Heft 11, Seite(n) 1298–1300

    Mesh-Begriff(e) Humans ; Cathepsin C/genetics ; Papillon-Lefevre Disease/genetics ; Acro-Osteolysis ; Mutation
    Chemische Substanzen Cathepsin C (EC 3.4.14.1)
    Sprache Englisch
    Erscheinungsdatum 2023-07-25
    Erscheinungsland England
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1093/ced/llad241
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Intense pulsed light may improve inflammatory acne through TNF-α down-regulation.

    Taylor, Marisa / Porter, Rebecca / Gonzalez, Maria

    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology

    2014  Band 16, Heft 2, Seite(n) 96–103

    Abstract: Background: Despite many studies on the action of yellow light in acne, its efficacy and mechanisms of action are still unclear.: Objectives: To determine if IPL can cause a clinical improvement in acne and whether it modifies TLR2 and TNFα ... ...

    Abstract Background: Despite many studies on the action of yellow light in acne, its efficacy and mechanisms of action are still unclear.
    Objectives: To determine if IPL can cause a clinical improvement in acne and whether it modifies TLR2 and TNFα expression.
    Methods: Twenty-one patients with mild to moderate acne involving their backs received 530 nm IPL treatments once every 2 weeks. Assessments at baseline and after the fourth treatment included lesion counts, Leeds grading and SER. Biopsies from the treatment area were taken at three time points. TLR2 expression was determined using immunohistochemistry, and TaqMan Low Density Arrays were used to measure TNFα, IL-8 and IL-10.
    Results: Inflamed lesion counts fell significantly by 28.0% (p = 0.002) but not the Leeds score, SER or non-inflamed lesions. A reduction in TNFα expression of 17.6% (p = 0.031) weakly correlated with the change in lesion counts. TLR2 expression fell by 2.6% (p < 0.001) but did not correlate with lesion counts. Neither IL-10 nor IL-8 expression was significantly altered.
    Conclusions: 530 nm IPL significantly reduces inflammatory lesions, where its efficacy will need optimising to make it a viable treatment option. Its mechanism seems to include a novel anti-TNFα effect, independent of IL-10 up-regulation.
    Mesh-Begriff(e) Acne Vulgaris ; Adult ; Back ; Cosmetic Techniques ; Down-Regulation ; Female ; Humans ; Immunohistochemistry ; Intense Pulsed Light Therapy/methods ; Interleukins/metabolism ; Male ; Middle Aged ; Toll-Like Receptor 2/metabolism ; Tumor Necrosis Factor-alpha/metabolism
    Chemische Substanzen Interleukins ; Toll-Like Receptor 2 ; Tumor Necrosis Factor-alpha
    Sprache Englisch
    Erscheinungsdatum 2014-04
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2146360-8
    ISSN 1476-4180 ; 1476-4172
    ISSN (online) 1476-4180
    ISSN 1476-4172
    DOI 10.3109/14764172.2013.864198
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Hyperandrogenism does not predispose patients to photoepilatory treatment failure: a single-center review.

    Taylor, Marisa / Gonzalez, Maria

    Journal of cosmetic dermatology

    2010  Band 9, Heft 3, Seite(n) 169–173

    Abstract: Studies have suggested that patients with PCOS tend to be more treatment resistant to light-mediated depilation compared with their non-PCOS counterparts. We conducted a retrospective assessment of 29 hirsute patients treated between January 2006 and ... ...

    Abstract Studies have suggested that patients with PCOS tend to be more treatment resistant to light-mediated depilation compared with their non-PCOS counterparts. We conducted a retrospective assessment of 29 hirsute patients treated between January 2006 and February 2007 to assess whether those with unsatisfactory hair clearance after treatment with intense pulsed light (IPL) were predominantly hyperandrogenic. The number of IPL sessions was also recorded for those patients failing to improve on treatment. Seventy-six percent had satisfactory hair clearance where hyperandrogenic patients dominated. All patients required an average of six treatments before discharge. Eighty-eight percent of poor responders were normoandrogenic. Our hyperandrogenic cohort appeared more responsive to IPL than the normoandrogenic patients. From our observations, the presence of hyperandrogenism does not indicate treatment resistance. This standpoint is unique and warrants a randomized trial directly comparing the two groups to investigate whether a positive or negative relationship actually exists.
    Mesh-Begriff(e) Adult ; Androgens/blood ; Female ; Follicle Stimulating Hormone/blood ; Genetic Predisposition to Disease ; Hair Removal/methods ; Hirsutism/therapy ; Humans ; Hyperandrogenism/complications ; Hyperandrogenism/genetics ; Light ; Luteinizing Hormone/blood ; Middle Aged ; Reference Values ; Retrospective Studies ; Treatment Failure ; Young Adult
    Chemische Substanzen Androgens ; Luteinizing Hormone (9002-67-9) ; Follicle Stimulating Hormone (9002-68-0)
    Sprache Englisch
    Erscheinungsdatum 2010-09
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/j.1473-2165.2010.00505.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Pathways to inflammation: acne pathophysiology.

    Taylor, Marisa / Gonzalez, Maria / Porter, Rebecca

    European journal of dermatology : EJD

    2011  Band 21, Heft 3, Seite(n) 323–333

    Abstract: Acne vulgaris affects as much as 80% of the adolescent population and persists in approximately 3% of middle-aged adults. Only a percentage of these persons seek medical help, however, acne can cause levels of anxiety and depression akin to a chronic ... ...

    Abstract Acne vulgaris affects as much as 80% of the adolescent population and persists in approximately 3% of middle-aged adults. Only a percentage of these persons seek medical help, however, acne can cause levels of anxiety and depression akin to a chronic illness. A recurring question from patients who seek help from various healthcare professionals - their pharmacist, family doctor or dermatologist, is "why?" They also ask questions about a possible familial link, the impact of their diet and the association with their hormones. The following review aims to link these factors with the end result - inflammation.
    Mesh-Begriff(e) Acne Vulgaris/etiology ; Acne Vulgaris/genetics ; Acne Vulgaris/pathology ; Genetic Predisposition to Disease ; Humans ; Inflammation/complications ; Inflammation/genetics ; Inflammation/pathology ; Skin/pathology
    Sprache Englisch
    Erscheinungsdatum 2011-05
    Erscheinungsland France
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1128666-0
    ISSN 1952-4013 ; 1167-1122
    ISSN (online) 1952-4013
    ISSN 1167-1122
    DOI 10.1684/ejd.2011.1357
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Successful Treatment of Autoimmune Disease-Associated Pyoderma Gangrenosum With the IL-1 Receptor Antagonist Anakinra: A Case Series of 3 Patients.

    Beynon, Celia / Chin, Mei Fong / Hunasehally, Prasad / Bhagwandas, Krishnan / Bevan, Martin / Taylor, Marisa / Lawson, Thomas

    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases

    2017  Band 23, Heft 3, Seite(n) 181–183

    Mesh-Begriff(e) Arthritis, Rheumatoid/complications ; Biopsy/methods ; Drug Resistance ; Female ; Humans ; Interleukin 1 Receptor Antagonist Protein/administration & dosage ; Lupus Erythematosus, Systemic/complications ; Middle Aged ; Pyoderma Gangrenosum/drug therapy ; Pyoderma Gangrenosum/etiology ; Pyoderma Gangrenosum/pathology ; Pyoderma Gangrenosum/physiopathology ; Receptors, Interleukin-1/antagonists & inhibitors ; Treatment Outcome
    Chemische Substanzen Interleukin 1 Receptor Antagonist Protein ; Receptors, Interleukin-1
    Sprache Englisch
    Erscheinungsdatum 2017-03-19
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 1283266-2
    ISSN 1536-7355 ; 1076-1608
    ISSN (online) 1536-7355
    ISSN 1076-1608
    DOI 10.1097/RHU.0000000000000511
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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