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  1. Article ; Online: Ultrasound-guided identification of superior mesenteric vein in robotic complete mesocolic excision for right colon cancer.

    Tejedor, P / Khan, J S

    Techniques in coloproctology

    2019  Volume 23, Issue 5, Page(s) 505–506

    MeSH term(s) Aged ; Colonic Neoplasms/surgery ; Female ; Humans ; Mesenteric Veins/diagnostic imaging ; Mesocolon/surgery ; Robotic Surgical Procedures ; Ultrasonography, Interventional
    Language English
    Publishing date 2019-04-29
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-019-01987-y
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    Zs.A 5842: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Tips and tricks: robotic low anterior resection - A video vignette.

    Sánchez-Rodríguez, María / Khan, Jim / Denost, Quentin / Tejedor, Patricia

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2024  

    Language English
    Publishing date 2024-03-31
    Publishing country England
    Document type Letter
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16970
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  3. Article ; Online: Surgical anterior plane for rectal surgeons: preserving Denonvilliers' fascia.

    Tejedor, P / Sagias, F / Khan, J

    Techniques in coloproctology

    2020  Volume 24, Issue 9, Page(s) 981–982

    MeSH term(s) Fascia ; Humans ; Pelvis ; Rectal Neoplasms ; Rectum/surgery ; Surgeons
    Language English
    Publishing date 2020-04-21
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-020-02224-7
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  4. Article ; Online: ILEOSTIM trial: a study protocol to evaluate the effectiveness of efferent loop stimulation before ileostomy reversal.

    Blanco, N / Oliva, I / Tejedor, P / Pastor, E / Alvarellos, A / Pastor, C / Baixauli, J / Arredondo, J

    Techniques in coloproctology

    2023  Volume 27, Issue 12, Page(s) 1251–1256

    Abstract: Purpose: A protective loop ileostomy is the most useful method to reduce sequelae in the event of an anastomotic leakage (AL) after rectal cancer surgery. However, it requires an additional stoma reversal surgery with its own potential complications. ... ...

    Abstract Purpose: A protective loop ileostomy is the most useful method to reduce sequelae in the event of an anastomotic leakage (AL) after rectal cancer surgery. However, it requires an additional stoma reversal surgery with its own potential complications. Postoperative ileus (POI) remains the most common complication after ileostomy reversal, which leads to an increase in morbidity, length of hospital stay (LOS) and overall healthcare costs. Several retrospective studies carried out in this field have concluded that there are insufficient evidence-based recommendations about the routine application of preoperative bowel stimulation in clinical practice. Here we discuss whether stimulation of the efferent limb before ileostomy reversal might reduce POI and improve postoperative outcomes.
    Methods: This is a multicentre randomised controlled trial to determine whether mechanical stimulation of the efferent limb during the 2 weeks before the ileostomy reversal would help to reduce the development of POI after surgery. This study was registered on Clinicaltrials.gov (NCT05302557). Stimulation will consist of infusing a solution of 500 ml of saline chloride solution mixed with a thickening agent (Resource
    Conclusion: The results of this study could provide some insights into the preoperative management of these patients.
    MeSH term(s) Humans ; Ileostomy/adverse effects ; Ileostomy/methods ; Retrospective Studies ; Postoperative Complications/etiology ; Postoperative Complications/prevention & control ; Anastomotic Leak/etiology ; Rectal Neoplasms/surgery ; Rectal Neoplasms/complications ; Rectum ; Ileus/etiology ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic
    Language English
    Publishing date 2023-04-27
    Publishing country Italy
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-023-02807-0
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    Zs.A 5842: Show issues Location:
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  5. Article ; Online: Patient Reported Outcomes following Cancer of the Rectum (PROCaRe): protocol of a prospective multicentre international study.

    Tejedor, Patricia / Arredondo, Jorge / Pellino, Gianluca / Pata, Francesco / Pastor, Carlos

    Techniques in coloproctology

    2023  Volume 27, Issue 12, Page(s) 1345–1350

    Abstract: Purpose: Rectal cancer surgery presents challenges in achieving good oncological results and preserving functional outcomes. Different surgical approaches, including open, laparoscopic, robotic and transanal techniques, have been employed, but there is ... ...

    Abstract Purpose: Rectal cancer surgery presents challenges in achieving good oncological results and preserving functional outcomes. Different surgical approaches, including open, laparoscopic, robotic and transanal techniques, have been employed, but there is a lack of consensus on the optimal approach, particularly in terms of functional results. This study aims to assess bowel function and to compare outcomes of patients that had undergone surgery for mid-low rectal cancer across different surgical approaches.
    Method: This is an international, multicentre, prospective cohort study. Inclusion criteria are patients diagnosed with rectal cancer below the peritoneal reflection, eligible for different surgical approaches for total mesorectal excision (TME). Data will be collected using validated questionnaires assessing bowel, sexual and urinary function, and quality of life (QOL). Secondary outcomes include short-term postoperative results. Data will be collected at baseline and 6, 12 and 24 months after index surgery or stoma reversal surgery.
    Conclusion: This study will provide insights into the impact of different approaches for TME on bowel, sexual and urinary function, and overall QOL of patients undergoing rectal cancer surgery. The findings will provide important information to optimise the surgical strategy and to improve patient care in this population.
    Trial registration: ClinicalTrials.gov, NCT04936581 (registered 23 June 2021).
    MeSH term(s) Humans ; Quality of Life ; Prospective Studies ; Rectum/surgery ; Rectal Neoplasms/surgery ; Laparoscopy/methods ; Patient Reported Outcome Measures ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Treatment Outcome ; Multicenter Studies as Topic
    Language English
    Publishing date 2023-09-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-023-02865-4
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  6. Article ; Online: Lymphatic drainage of a splenic flexure tumour defined by intra-operative indocyanine green mapping - a video vignette.

    Tejedor, P / Sagias, F / Khan, J

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2019  Volume 22, Issue 1, Page(s) 106–107

    MeSH term(s) Aged ; Colectomy ; Colon, Transverse/surgery ; Coloring Agents ; Humans ; Indocyanine Green ; Intraoperative Care/methods ; Lymph Nodes/diagnostic imaging ; Lymph Nodes/surgery ; Male ; Manual Lymphatic Drainage/methods ; Peritoneal Neoplasms/surgery
    Chemical Substances Coloring Agents ; Indocyanine Green (IX6J1063HV)
    Language English
    Publishing date 2019-09-13
    Publishing country England
    Document type Case Reports ; Letter ; Video-Audio Media
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.14826
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  7. Article ; Online: Can complete mesocolon excision be considered the treatment of choice in right hemicolectomy for cancer?

    Tejedor, Patricia / Francis, Nader

    Cirugia espanola

    2020  Volume 99, Issue 4, Page(s) 255–257

    Title translation ¿ Se puede consiedar la escisión completa del mesocolon el tratamiento de eleccion en la hemicolectomia derecha por cancer?
    MeSH term(s) Colectomy ; Colonic Neoplasms/surgery ; Humans ; Mesocolon/surgery
    Language Spanish
    Publishing date 2020-04-25
    Publishing country Spain
    Document type Editorial
    ISSN 2173-5077
    ISSN (online) 2173-5077
    DOI 10.1016/j.ciresp.2020.03.005
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  8. Article ; Online: Preoperative Planning of D3 Right Colectomy With Three-Dimensional Vascular Reconstruction.

    Colombari, Renan Carlo / Pérez-Carpio, Carlota / Sánchez Rodriguez, María / Martínez, Javier / Dujovne, Paula / Zorrilla, Jaime / Jiménez-Gomez, Luis M / Tejedor, Patricia

    Diseases of the colon and rectum

    2024  

    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 212581-x
    ISSN 1530-0358 ; 0012-3706
    ISSN (online) 1530-0358
    ISSN 0012-3706
    DOI 10.1097/DCR.0000000000003119
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  9. Article ; Online: Consensus statements on complete mesocolic excision for right-sided colon cancer-technical steps and training implications.

    Tejedor, Patricia / Francis, Nader / Jayne, David / Hohenberger, Werner / Khan, Jim

    Surgical endoscopy

    2022  Volume 36, Issue 8, Page(s) 5595–5601

    Abstract: Background: CME is a radical resection for colon cancer, but the procedure is technically demanding with significant variation in its practice. A standardised approach to the optimal technique and training is, therefore, desirable to minimise technical ... ...

    Abstract Background: CME is a radical resection for colon cancer, but the procedure is technically demanding with significant variation in its practice. A standardised approach to the optimal technique and training is, therefore, desirable to minimise technical hazards and facilitate safe dissemination. The aim is to develop an expert consensus on the optimal technique for Complete Mesocolic Excision (CME) for right-sided and transverse colon cancer to guide safe implementation and training pathways.
    Methods: Guidance was developed following a modified Delphi process to draw consensus from 55 international experts in CME and surgical education representing 18 countries. Domain topics were formulated and subdivided into questions pertinent to different aspects of CME practice. A three-round Delphi voting on 25 statements based on the specific questions and 70% agreement was considered as consensus.
    Results: Twenty-three recommendations for CME procedure were agreed on, describing the technique and optimal training pathway. CME is recommended as the standard of care resection for locally advanced colon cancer. The essential components are central vascular ligation, exposure of the superior mesenteric vein and excision of an intact mesocolon. Key anatomical landmarks to perform a safe CME dissection include identification of the ileocolic pedicle, superior mesenteric vein and root of the mesocolon. A proficiency-based multimodal training curriculum for CME was proposed including a formal proctorship programme.
    Conclusions: Consensus on standardisation of technique and training framework for complete mesocolic excision was agreed upon by a panel of experts to guide current practice and provide a quality control framework for future studies.
    MeSH term(s) Colectomy/methods ; Colonic Neoplasms/surgery ; Humans ; Laparoscopy/methods ; Lymph Node Excision/methods ; Mesocolon/surgery
    Language English
    Publishing date 2022-07-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-021-08395-0
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  10. Article ; Online: The ELECLA trial: A multicentre randomised control trial on outcomes of neoadjuvant treatment on locally advanced colon cancer.

    Arredondo, Jorge / Almeida, Ana / Castañón, Carmen / Sánchez, Carlos / Villafañe, Amaya / Tejedor, Patricia / Simó, Vicente / Baixauli, Jorge / Rodríguez, Javier / Pastor, Carlos

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2024  Volume 26, Issue 4, Page(s) 745–753

    Abstract: Background: Colon cancer (CC) is a public health concern with increasing incidence in younger populations. Treatment for locally advanced CC (LACC) involves oncological surgery and adjuvant chemotherapy (AC) to reduce recurrence and improve overall ... ...

    Abstract Background: Colon cancer (CC) is a public health concern with increasing incidence in younger populations. Treatment for locally advanced CC (LACC) involves oncological surgery and adjuvant chemotherapy (AC) to reduce recurrence and improve overall survival (OS). Neoadjuvant chemotherapy (NAC) is a novel approach for the treatment of LACC, and research is underway to explore its potential benefit in terms of survival. This trial will assess the efficacy of NAC in LACC.
    Methods: This is a multicentre randomised, parallel-group, open label controlled clinical trial. Participants will be selected based on homogenous inclusion criteria and randomly assigned to two treatment groups: NAC, surgery, and AC or surgery followed by AC. The primary aim of this study is to evaluate the 2-year progression-free survival (PFS), with secondary outcomes including 5-year PFS, 2- and 5-year OS, toxicity, radiological and pathological response, morbidity, and mortality.
    Discussion: The results of this study will determine whether NAC induces a clinical and histological tumour response in patients with CCLA and if this treatment sequence improves survival without increasing morbidity and mortality.
    Registration number: NCT04188158.
    MeSH term(s) Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Chemotherapy, Adjuvant/methods ; Colectomy/methods ; Colonic Neoplasms/pathology ; Colonic Neoplasms/mortality ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/therapy ; Colonic Neoplasms/surgery ; Neoadjuvant Therapy/methods ; Progression-Free Survival ; Randomized Controlled Trials as Topic ; Treatment Outcome ; Multicenter Studies as Topic
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16908
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