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Article ; Online: Costal margin injuries and trans-diaphragmatic intercostal hernia: Presentation, management and outcomes according to the Sheffield classification.

Byers, Jonathan L / Rao, Jagan N / Socci, Laura / Hopkinson, David N / Tenconi, Sara / Edwards, John G

The journal of trauma and acute care surgery

2023 Volume 95, Issue 6, Page(s) 839–845

Abstract: Background: Costal margin rupture (CMR) injuries are under-diagnosed and inconsistently managed, while carrying significant symptomatic burden. We hypothesized that the Sheffield Classification system of CMR injuries would relate to injury patterns and ... ...

Abstract	Background: Costal margin rupture (CMR) injuries are under-diagnosed and inconsistently managed, while carrying significant symptomatic burden. We hypothesized that the Sheffield Classification system of CMR injuries would relate to injury patterns and management options. Methods: Data were collected prospectively between 2006 and 2023 at a major trauma center in the United Kingdom. Computed tomography scans were interrogated and injuries were categorized according to the Sheffield Classification. Clinical, radiologic, management and outcome variables were assessed. Results: Fifty-four patients were included in the study. Intercostal hernia (IH) was present in 30 patients and associated with delayed presentation ( p = 0.004), expulsive mechanism of injury (i.e. such as occurs with coughing, sneezing, or retching), higher body mass index ( p < 0.001), and surgical management ( p = 0.02). There was a bimodal distribution of the level of the costal margin rupture, with IH Present and expulsive mechanism injuries occurring predominantly at the ninth costal cartilage, and IH Absent cases and other mechanisms at the seventh costal cartilage ( p < 0.001). There were correlations between the costal cartilage being thin at the site of the CMR and the presence of IH and expulsive etiology ( p < 0.001). Management was conservative in 23 and surgical in 31 cases. Extrathoracic mesh IH repairs were performed in 3, Double Layer Mesh Repairs in 8, Suture IH repairs in 5, CMR plating in 8, CMR sutures in 2, and associated Surgical Stabilization of Rib Fractures in 11 patients. There was one postoperative death. There were seven repeat surgical procedures in five patients. Conclusion: The Sheffield Classification is associated statistically with presentation, related chest wall injury patterns, and type of definitive management. Further collaborative data collection is required to determine the optimal management strategies. Level of evidence: Therapeutic/Care Management; Level III.
MeSH term(s)	Humans ; Rib Cage/surgery ; Hernia/etiology ; Hernia, Hiatal/complications ; Hernias, Diaphragmatic, Congenital/surgery ; Herniorrhaphy/methods ; Rupture/surgery
Language	English
Publishing date	2023-08-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2651070-4
ISSN	2163-0763 ; 2163-0755
ISSN (online)	2163-0763
ISSN	2163-0755
DOI	10.1097/TA.0000000000004068
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Zs.A 127: Show issues

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Article ; Online: Survival following lung volume reduction procedures: results from the UK Lung Volume Reduction (UKLVR) registry.

Buttery, S C / Lewis, A / Alzetani, A / Bolton, C E / Curtis, K J / Dodd, J W / Habib, A M / Hussain, A / Havelock, T / Jordan, S / Kallis, C / Kemp, S V / Kirk, A / Lawson, R A / Mahadeva, R / Munavvar, M / Naidu, B / Rathinam, S / Shackcloth, M /

Shah, P L / Tenconi, S / Hopkinson, N S

BMJ open respiratory research

2024 Volume 11, Issue 1

Abstract: Introduction: Lung volume reduction surgery (LVRS) and endobronchial valve (EBV) placement can produce substantial benefits in appropriately selected people with emphysema. The UK Lung Volume Reduction (UKLVR) registry is a national multicentre ... ...

Abstract	Introduction: Lung volume reduction surgery (LVRS) and endobronchial valve (EBV) placement can produce substantial benefits in appropriately selected people with emphysema. The UK Lung Volume Reduction (UKLVR) registry is a national multicentre observational study set up to support quality standards and assess outcomes from LVR procedures at specialist centres across the UK. Methods: Data were analysed for all patients undergoing an LVR procedure (LVRS/EBV) who were recruited into the study at participating centres between January 2017 and June 2022, including; disease severity and risk assessment, compliance with guidelines for selection, procedural complications and survival to February 2023. Results: Data on 541 patients from 14 participating centres were analysed. Baseline disease severity was similar in patients who had surgery n=244 (44.9%), or EBV placement n=219 (40.9%), for example, forced expiratory volume in 1 s (FEV
MeSH term(s)	Humans ; Male ; Emphysema ; Lung/surgery ; Pneumonectomy/adverse effects ; Pneumonectomy/methods ; Pulmonary Emphysema/surgery ; Registries ; United Kingdom ; Female
Language	English
Publishing date	2024-02-29
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2736454-9
ISSN	2052-4439 ; 2052-4439
ISSN (online)	2052-4439
ISSN	2052-4439
DOI	10.1136/bmjresp-2023-002092
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Article ; Online: Surgery as part of radical treatment for malignant pleural mesothelioma.

Waller, David A / Tenconi, Sara

Current opinion in pulmonary medicine

2017 Volume 23, Issue 4, Page(s) 334–338

Abstract: Purpose of review: To review the latest developments in surgery for malignant pleural mesothelioma both in patient selection, surgical technique, and strategy.: Recent findings: The International Association for the Study of Lung Cancer mesothelioma ... ...

Abstract	Purpose of review: To review the latest developments in surgery for malignant pleural mesothelioma both in patient selection, surgical technique, and strategy. Recent findings: The International Association for the Study of Lung Cancer mesothelioma staging project has produced data to inform the 8th tumour node metastasis revision. The difficulty in clinical N staging and clinical T staging are highlighted and the importance of tumour volume is recognized. New imaging techniques can be utilized to assess tumour volume. The transition from extrapleural pneumonectomy to lung-sparing pleurectomy/decortication has extended the role of cancer-directed surgery into a more elderly population. More aggressive multimodality regimes, including induction radiotherapy are available to a selected population and adjuvant radiotherapy and chemotherapy are feasible in the elderly majority. Additional chemotherapy should not be delayed in those with poorer prognosis node positive, nonepithelioid disease. Summary: Radical surgery for malignant pleural mesothelioma can achieve significant survival when targeted in those with the best prognosis by careful staging. It can be made more accessible by lung preservation without compromising outcome. It should be part of multimodality therapy.
MeSH term(s)	Combined Modality Therapy ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Mesothelioma/surgery ; Mesothelioma, Malignant ; Neoplasm Staging ; Patient Selection ; Pleura/pathology ; Pleura/surgery ; Pleural Neoplasms/pathology ; Pleural Neoplasms/surgery ; Pneumonectomy/methods ; Radiotherapy, Adjuvant ; Thoracic Surgical Procedures/methods ; Treatment Outcome
Language	English
Publishing date	2017-05-24
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1285505-4
ISSN	1531-6971 ; 1070-5287 ; 1078-1641
ISSN (online)	1531-6971
ISSN	1070-5287 ; 1078-1641
DOI	10.1097/MCP.0000000000000389
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Zs.A 4900: Show issues

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Article ; Online: Standardizing Surgical Treatment of Malignant Pleural Mesothelioma.

Waller, David A / Bilancia, Rocco / Bille, Andrea / Tenconi, Sara

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

2020 Volume 15, Issue 5, Page(s) e73–e74

MeSH term(s)	Humans ; Lung Neoplasms/surgery ; Mesothelioma/surgery ; National Cancer Institute (U.S.) ; Pleural Neoplasms/surgery ; United States
Language	English
Publishing date	2020-04-27
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	2432037-7
ISSN	1556-1380 ; 1556-0864
ISSN (online)	1556-1380
ISSN	1556-0864
DOI	10.1016/j.jtho.2019.12.131
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Zs.A 6664: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 652: Show issues

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Article ; Online: The effects of an intentional transition from extrapleural pneumonectomy to extended pleurectomy/decortication.

Sharkey, Annabel J / Tenconi, Sara / Nakas, Apostolos / Waller, David A

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

2016 Volume 49, Issue 6, Page(s) 1632–1641

Abstract: Objectives: For many years, extrapleural pneumonectomy (EPP) was the operation of choice for the radical management of pleural mesothelioma in the UK. However, doubts surrounding the efficacy of EPP, and the change in demographics of the affected ... ...

Abstract	Objectives: For many years, extrapleural pneumonectomy (EPP) was the operation of choice for the radical management of pleural mesothelioma in the UK. However, doubts surrounding the efficacy of EPP, and the change in demographics of the affected population, have prompted a transition in our practice towards extended pleurectomy/decortication (EPD). The aim of this study was to determine the effects an intentional transition from EPP to EPD has had on patient outcome. Methods: Data from 362 patients undergoing radical surgery (229 EPD, 133 EPP) during 1999-2014 were included. Demographics and outcome were compared between the two groups; EPP versus EPD. Results: The median age of patients undergoing EPD was significantly higher than those undergoing EPP [57 years (range 14-70 years) vs 65 years (range 42-81 years), P < 0.001]. There was a significantly higher proportion of patients with performance status ≥1 in the EPD group (46.3 vs 35.4%, P = 0.047). There was no difference in the median length of hospital stay between the two groups [14 days (range 1-133 days) vs 13 days (range 0-93 days), P = 0.409]. There was also no difference between the groups in terms of in-hospital mortality (EPP 5.3% and EPD 6.6%, P = 0.389), 30-day mortality [EPP 8 (6.0%) and EPD 8 (3.5%), P = 0.294] or 90-day mortality [EPP 18 (13.5%) and EPD 21 (9.2%), P = 0.220]. There was a significantly higher early reoperation rate in the EPP group (15.0 vs 6.2%, P = 0.008) but a significantly higher late reoperation rate in the EPD group (0.8 vs 5.3%, P = 0.037). There was no significant difference in overall survival or disease-free interval between the two groups (P = 0.899 and P = 0.399, respectively). However, overall survival was significantly greater in patients over the age of 65 undergoing EPD (12.5 vs 4.7 months, P = 0.001). Conclusion: The transition from EPP to EPD in our standard practice has enabled us to operate on more elderly, frail patients with no significant increase in use of hospital resources, and without detriment to overall survival.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Chemotherapy, Adjuvant ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Mesothelioma/surgery ; Mesothelioma/therapy ; Middle Aged ; Pleural Neoplasms/surgery ; Pleural Neoplasms/therapy ; Pneumonectomy/methods ; Pneumonectomy/trends ; Professional Practice/trends ; Radiotherapy, Adjuvant ; Reoperation/statistics & numerical data ; Retrospective Studies ; Treatment Outcome ; Young Adult
Language	English
Publishing date	2016-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	639293-3
ISSN	1873-734X ; 1010-7940 ; 1567-4258
ISSN (online)	1873-734X
ISSN	1010-7940 ; 1567-4258
DOI	10.1093/ejcts/ezv403
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Zs.A 2303: Show issues

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Article ; Online: Extended pleurectomy decortication for malignant pleural mesothelioma in the elderly: the need for an inclusive yet selective approach.

Sharkey, Annabel Jane / Bilancia, Rocco / Tenconi, Sara / Nakas, Apostolos / Waller, David A

Interactive cardiovascular and thoracic surgery

2017 Volume 25, Issue 5, Page(s) 696–702

Abstract: Objectives: The median age at diagnosis of patients with pleural mesothelioma in the UK is 73 years. Recent series have shown the feasibility of extended pleurectomy decortication in the elderly, but with continuing debate about the efficacy of this ... ...

Abstract	Objectives: The median age at diagnosis of patients with pleural mesothelioma in the UK is 73 years. Recent series have shown the feasibility of extended pleurectomy decortication in the elderly, but with continuing debate about the efficacy of this treatment, we reviewed our experience to identify more detailed selection criteria. Methods: We reviewed prospectively collected data on all patients from 1999 to 2016 undergoing extended pleurectomy decortication. We compared clinical and pathological outcomes and survival data from patients 70 years and older (≥70 years) with those younger than 70 years (<70 years). Results: Eighty-two of the 300 (27.3%) patients were ≥70 years of age at the time of surgery. More patients in the elderly group required intensive care postoperatively (6.2 vs 16.7%, P = 0.01) and developed atrial fibrillation (14.4 vs 24.4%, P = 0.05). There was no intergroup difference in length of hospital stay or in in-hospital, 30-day or 90-day mortality. Elderly patients were less likely to receive neoadjuvant (<70 years 21.2%, ≥70 years 11.0%; P = 0.045) or adjuvant chemotherapy (<70 years 45.4%, ≥70 years 29.3%; P = 0.04). Median overall survival was similar: <70 years 14.0 months, ≥70 years 10.3 months; P = 0.29. However, in node-positive patients, survival was poorer in the elderly (13.0 vs 9.1 months, P = 0.05), particularly in those with non-epithelioid tumours (3.8 vs 6.7 months, P = 0.04). On multivariable analysis, age was not a significant prognostic factor, although lack of adjuvant therapy (P = 0.001) and admission to the intensive care unit (P < 0.001) remained poor prognostic factors. Conclusions: Although age in isolation should not be an exclusion criterion for extended pleurectomy decortication for mesothelioma, in the elderly, a more rigorous preoperative evaluation of nodal disease and an additional assessment of fitness for adjuvant chemotherapy are recommended.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/mortality ; Lung Neoplasms/surgery ; Male ; Mesothelioma/diagnosis ; Mesothelioma/mortality ; Mesothelioma/surgery ; Mesothelioma, Malignant ; Middle Aged ; Patient Selection ; Pleura/diagnostic imaging ; Pleura/surgery ; Pleural Neoplasms/diagnosis ; Pleural Neoplasms/mortality ; Pleural Neoplasms/surgery ; Positron-Emission Tomography ; Retrospective Studies ; Survival Rate/trends ; Thoracic Surgical Procedures/methods ; Tomography, X-Ray Computed ; Treatment Outcome ; United Kingdom/epidemiology
Language	English
Publishing date	2017-10-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2095298-3
ISSN	1569-9285 ; 1569-9293
ISSN (online)	1569-9285
ISSN	1569-9293
DOI	10.1093/icvts/ivx221
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Zs.A 5730: Show issues

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Article ; Online: Lung volume reduction surgery

The European respiratory journal

2023 Volume 61, Issue 4

Abstract: Background: Lung volume reduction surgery (LVRS) and bronchoscopic lung volume reduction (BLVR) with endobronchial valves can improve outcomes in appropriately selected patients with emphysema. However, no direct comparison data exist to inform clinical ...

Abstract	Background: Lung volume reduction surgery (LVRS) and bronchoscopic lung volume reduction (BLVR) with endobronchial valves can improve outcomes in appropriately selected patients with emphysema. However, no direct comparison data exist to inform clinical decision making in people who appear suitable for both procedures. Our aim was to investigate whether LVRS produces superior health outcomes when compared with BLVR at 12 months. Methods: This multicentre, single-blind, parallel-group trial randomised patients from five UK hospitals, who were suitable for a targeted lung volume reduction procedure, to either LVRS or BLVR and compared outcomes at 1 year using the i-BODE score. This composite disease severity measure includes body mass index, airflow obstruction, dyspnoea and exercise capacity (incremental shuttle walk test). The researchers responsible for collecting outcomes were masked to treatment allocation. All outcomes were assessed in the intention-to-treat population. Results: 88 participants (48% female, mean±sd age 64.6±7.7 years, forced expiratory volume in 1 s percent predicted 31.0±7.9%) were recruited at five specialist centres across the UK and randomised to either LVRS (n=41) or BLVR (n=47). At 12 months follow-up, the complete i-BODE was available in 49 participants (21 LVRS/28 BLVR). Neither improvement in the i-BODE score (LVRS -1.10±1.44 Conclusion: Our findings do not support the hypothesis that LVRS is a substantially superior treatment to BLVR in individuals who are suitable for both treatments.
MeSH term(s)	Humans ; Female ; Middle Aged ; Aged ; Male ; Pneumonectomy/methods ; Single-Blind Method ; Lung/surgery ; Pulmonary Emphysema/surgery ; Forced Expiratory Volume ; Treatment Outcome ; Bronchoscopy/methods
Language	English
Publishing date	2023-04-27
Publishing country	England
Document type	Randomized Controlled Trial ; Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	639359-7
ISSN	1399-3003 ; 0903-1936
ISSN (online)	1399-3003
ISSN	0903-1936
DOI	10.1183/13993003.02063-2022
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Zs.A 2322: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 292: Show issues

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Article ; Online: Rehabilitation for lung cancer patients undergoing surgery: results of the PUREAIR randomized trial.

Tenconi, Sara / Mainini, Carlotta / Rapicetta, Cristian / Braglia, Luca / Galeone, Carla / Cavuto, Silvio / Merlo, Domenico F / Costi, Stefania / Paci, Massimiliano / Piro, Roberto / Fugazzaro, Stefania

European journal of physical and rehabilitation medicine

2021 Volume 57, Issue 6, Page(s) 1002–1011

Abstract: Background: Surgery for non-small cell lung cancer is proven to be the most effective treatment in early stages, although concerns exist on its negative impact on patients' overall fitness.: Aim: To establish whether intensive pulmonary ... ...

Abstract	Background: Surgery for non-small cell lung cancer is proven to be the most effective treatment in early stages, although concerns exist on its negative impact on patients' overall fitness. Aim: To establish whether intensive pulmonary rehabilitation, preoperative and postoperative, improves exercise capacity in patients undergoing lung resection. Design: Single center, unblinded, designed for superiority, 1:1 randomized controlled trial with two parallel arms. Setting: S. Maria Nuova Hospital of Reggio Emilia (Reggio Emilia, Italy). Population: Patients referred from local lung cancer multidisciplinary team for lung resection. Methods: Patients were randomized to either standard of care (SC) or SC + intensive perioperative pulmonary rehabilitation (SC+PR). The primary aim was to investigate the effectiveness of pulmonary rehabilitation in improving exercise capacity six months after surgery. Additionally, we wanted to investigate the same effect shortly after surgery (at one month), as well as the overall impact of rehabilitation on lung function, postoperative complications and length of stay, quality of life, mood disturbances and pain. Sample was sized based on the primary outcome assuming a minimal clinically significant difference of 25 meters in exercise tolerance, measured with 6 minutes walking test. Results: The exercise tolerance at 6 months after surgery was significantly higher in patients undertaking PR compared to SC (+48.9 meters vs. -7.5 meters respectively, difference: +56.4 meters, 95% CI: 29.6-83.0, P<0.001) and it showed significantly lower impairment at 1 month after surgery in the intervention group (-3.0 meters vs. -30.1 meters difference: +27.1 meters, 95% CI: 3.4-50.8, P=0.025). No other significant differences between groups were found. Conclusions: Comparison between groups showed that pulmonary rehabilitation, administered pre and postoperatively, significantly improved exercise capacity at 6 months in patients undergoing lung resection; it also significantly reduced the decrease in exercise tolerance observed 1 month after surgery. Clinical rehabilitation impact: The PUREAIR trial highlights the importance of combined preoperative and postoperative rehabilitation in reducing physical deconditioning in lung cancer patients undergoing surgery. Comprehensive pulmonary rehabilitation improves exercise capacity at 1 and 6 months after surgery. The PUREAIR trial results increase knowledge on comprehensive rehabilitation's outcomes in the first six months after surgery.
MeSH term(s)	Carcinoma, Non-Small-Cell Lung/surgery ; Humans ; Lung Neoplasms/surgery ; Postoperative Period ; Quality of Life ; Walk Test
Language	English
Publishing date	2021-05-27
Publishing country	Italy
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.21.06789-7
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Zs.B 1388: Show issues

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Article ; Online: European Society of Thoracic Surgeons electronic quality of life application after lung resection: field testing in a clinical setting.

Pompili, Cecilia / Trevis, Jason / Patella, Miriam / Brunelli, Alessandro / Libretti, Lidia / Novoa, Nuria / Scarci, Marco / Tenconi, Sara / Dunning, Joel / Cafarotti, Stefano / Koller, Michael / Velikova, Galina / Shargall, Yaron / Raveglia, Federico

Interactive cardiovascular and thoracic surgery

2021 Volume 32, Issue 6, Page(s) 911–920

Abstract: Objectives: Technology has the potential to assist healthcare professionals in improving patient-doctor communication during the surgical journey. Our aims were to assess the acceptability of a quality of life (QoL) application (App) in a cohort of ... ...

Abstract	Objectives: Technology has the potential to assist healthcare professionals in improving patient-doctor communication during the surgical journey. Our aims were to assess the acceptability of a quality of life (QoL) application (App) in a cohort of cancer patients undergoing lung resections and to depict the early perioperative trajectory of QoL. Methods: This multicentre (Italy, UK, Spain, Canada and Switzerland) prospective longitudinal study with repeated measures used 12 lung surgery-related validated questions from the European Organisation for Research and Treatment of Cancer Item Bank. Patients filled out the questionnaire preoperatively and 1, 7, 14, 21 and 28 days after surgery using an App preinstalled in a tablet. A one-way repeated measures analysis of variance was run to determine if there were differences in QoL over time. Results: A total of 103 patients consented to participate in the study (83 who had lobectomies, 17 who had segmentectomies and 3 who had pneumonectomies). Eighty-three operations were performed by video-assisted thoracoscopic surgery (VATS). Compliance rates were 88%, 90%, 88%, 82%, 71% and 56% at each time point, respectively. The results showed that the operation elicited statistically significant worsening in the following symptoms: shortness of breath (SOB) rest (P = 0.018), SOB walk (P < 0.001), SOB stairs (P = 0.015), worry (P = 0.003), wound sensitivity (P < 0.001), use of arm and shoulder (P < 0.001), pain in the chest (P < 0.001), decrease in physical capability (P < 0.001) and scar interference on daily activity (P < 0.001) during the first postoperative month. SOB worsened immediately after the operation and remained low at the different time points. Worry improved following surgery. Surgical access and forced expiratory volume in 1 s (FEV1) are the factors that most strongly affected the evolution of the symptoms in the perioperative period. Conclusions: We observed good early compliance of patients operated on for lung cancer with the European Society of Thoracic Surgeons QoL App. We determined the evolution of surgery-related QoL in the immediate postoperative period. Monitoring these symptoms remotely may reduce hospital appointments and help to establish early patient-support programmes.
MeSH term(s)	Electronics ; Humans ; Longitudinal Studies ; Lung/surgery ; Lung Neoplasms/surgery ; Pneumonectomy/adverse effects ; Prospective Studies ; Quality of Life ; Surgeons ; Thoracic Surgery, Video-Assisted/adverse effects
Language	English
Publishing date	2021-04-28
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
ZDB-ID	2095298-3
ISSN	1569-9285 ; 1569-9293
ISSN (online)	1569-9285
ISSN	1569-9293
DOI	10.1093/icvts/ivab030
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Article ; Online: Diagnostic pitfalls in the preoperative 18F-FDG PET/CT evaluation of a case of giant malignant solitary fibrous tumor of the pleura.

Lococo, F / Rapicetta, C / Ricchetti, T / Cavazza, A / Filice, A / Treglia, G / Tenconi, S / Paci, M / Sgarbi, G

Revista espanola de medicina nuclear e imagen molecular

2014 Volume 33, Issue 2, Page(s) 109–111

Abstract: Solitary fibrous tumor of the pleura (SFTP) is an uncommon entity, generally with an indolent behavior. Nevertheless, some malignant forms have been rarely reported. These, often have an aggressive biological behavior with pathological findings of ... ...

Abstract	Solitary fibrous tumor of the pleura (SFTP) is an uncommon entity, generally with an indolent behavior. Nevertheless, some malignant forms have been rarely reported. These, often have an aggressive biological behavior with pathological findings of invasiveness. The preoperative diagnosis and evaluation of the grade of malignancy are extremely challenging. Herein we report a case of a 64-year-old man who presented with a left giant intra-thoracic mass imaged with fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG/PET-CT) and sampled via fine-needle aspiration biopsy (FNAB). Imaging and FNAB findings showed suspicion of a benign form of SFTP. Surgical radical resection of the giant mass was performed. The definitive histological diagnosis showed a malignant SFTP. Based on this report, we take the opportunity to briefly discuss the insidious pitfalls concerning the radiological and (18)F-FDG/PET-CT features as well as cyto/histological findings in the pre-operative diagnostic work-up examination of this rare entity.
MeSH term(s)	Fluorodeoxyglucose F18 ; Humans ; Male ; Middle Aged ; Multimodal Imaging ; Positron-Emission Tomography ; Preoperative Care ; Radiopharmaceuticals ; Solitary Fibrous Tumor, Pleural/diagnosis ; Solitary Fibrous Tumor, Pleural/surgery ; Tomography, X-Ray Computed
Chemical Substances	Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2014-03
Publishing country	Spain
Document type	Case Reports ; Journal Article
ZDB-ID	2911865-7
ISSN	2253-8070 ; 2253-654X
ISSN (online)	2253-8070
ISSN	2253-654X
DOI	10.1016/j.remn.2013.07.007
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In stock of ZB MED Cologne/Königswinter

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