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  1. Article ; Online: The Importance of RSV Epidemiological Surveillance: A Multicenter Observational Study of RSV Infection during the COVID-19 Pandemic.

    Pruccoli, Giulia / Castagno, Emanuele / Raffaldi, Irene / Denina, Marco / Barisone, Elisa / Baroero, Luca / Timeus, Fabio / Rabbone, Ivana / Monzani, Alice / Terragni, Gian Maria / Lovera, Cristina / Brach Del Prever, Adalberto / Manzoni, Paolo / Barbaglia, Michelangelo / Roasio, Luca / De Franco, Simona / Calitri, Carmelina / Lupica, Maddalena / Felici, Enrico /
    Marciano, Cinzia / Santovito, Savino / Militerno, Gaia / Abrigo, Enrica / Curtoni, Antonio / Quarello, Paola / Bondone, Claudia / Garazzino, Silvia

    Viruses

    2023  Volume 15, Issue 2

    Abstract: The restrictive measures adopted worldwide against SARS-CoV-2 produced a drastic reduction in respiratory pathogens, including RSV, but a dramatic rebound was thereafter reported. In this multicenter retrospective observational study in 15 Pediatric ... ...

    Abstract The restrictive measures adopted worldwide against SARS-CoV-2 produced a drastic reduction in respiratory pathogens, including RSV, but a dramatic rebound was thereafter reported. In this multicenter retrospective observational study in 15 Pediatric Emergency Departments, all children <3 years old with RSV infection admitted between 1 September and 31 December 2021 were included and compared to those admitted in the same period of 2020 and 2019. The primary aim was to evaluate RSV epidemiology during and after the COVID-19 pandemic peak. The secondary aims were to evaluate the clinical features of children with RSV infection. Overall, 1015 children were enrolled: 100 in 2019, 3 in 2020 and 912 in 2021. In 2019, the peak was recorded in December, and in 2021, it was recorded in November. Comparing 2019 to 2021, in 2021 the median age was significantly higher and the age group 2-3 years was more affected. Admissions were significantly higher in 2021 than in 2020 and 2019, and the per-year hospitalization rate was lower in 2021 (84% vs. 93% in 2019), while the duration of admissions was similar. No difference was found in severity between 2019-2020-2021. In conclusion, after the COVID-19 pandemic, an increase in RSV cases in 2021 exceeding the median seasonal peak was detected, with the involvement of older children, while no difference was found in severity.
    MeSH term(s) Child ; Humans ; Adolescent ; Child, Preschool ; COVID-19/epidemiology ; SARS-CoV-2 ; Pandemics ; Respiratory Syncytial Virus Infections/epidemiology ; Emergency Service, Hospital
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15020280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pediatric admissions to emergency departments of North-Western Italy during COVID-19 pandemic: A retrospective observational study.

    Raffaldi, Irene / Castagno, Emanuele / Fumi, Ilaria / Bondone, Claudia / Ricceri, Fulvio / Besenzon, Luigi / Brach Del Prever, Adalberto / Capalbo, Pina / Cosi, Gianluca / Felici, Enrico / Fusco, Patrizia / Gallina, Maria Rita / Garofalo, Franco / Gianino, Paola / Guala, Andrea / Haitink, Oscar / Manzoni, Paolo / Marra, Antonio / Rabbone, Ivana /
    Roasio, Luca / Santovito, Savino / Serra, Alberto / Tappi, Eleonora / Terragni, Gian Maria / Timeus, Fabio S / Torielli, Flaminia / Vigo, Alessandro / Urbino, Antonio F

    The Lancet regional health. Europe

    2021  Volume 5, Page(s) 100081

    Abstract: Background: COVID-19 pandemic caused huge decrease of pediatric admissions to Emergency Department (ED), arising concerns about possible delays in diagnosis and treatment of severe disorders.: Methods: Impact of COVID-19 on Pediatric Emergency Room ( ... ...

    Abstract Background: COVID-19 pandemic caused huge decrease of pediatric admissions to Emergency Department (ED), arising concerns about possible delays in diagnosis and treatment of severe disorders.
    Methods: Impact of COVID-19 on Pediatric Emergency Room (ICOPER) was a retrospective multicentre observational study including 23 Italian EDs.All the children <18 years admitted, between March 9th and May 3rd 2020 stratified by age, priority code, cause of admission and outcome have been included and compared to those admitted in the same period of 2019.Our objectives were to assess the characteristics of pediatric admissions to EDs since COVID-19 outbreak until the end of lockdown, and to describe the features of critical children.
    Findings: 16,426 children were admitted in 2020, compared to 55,643 in 2019 (-70·48%). Higher reduction was reported in hospitals without Pediatric Intensive Care Unit (PICU) (-73·38%) than in those with PICU (-64·08%) (
    Interpretation: Admissions with low priority decreased significantly more than those with high priority; we suppose that the fear of being infected in hospital maybe overcame the concerns of caregivers. Compared to 2019, no significant referral delay by caregivers was reported. Our data suggest the need of adaptation of EDs and primary care services to different needs of children during COVID-9 pandemic.
    Language English
    Publishing date 2021-03-18
    Publishing country England
    Document type Journal Article
    ISSN 2666-7762
    ISSN (online) 2666-7762
    DOI 10.1016/j.lanepe.2021.100081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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