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Artikel ; Online: Effect of the concentration of water in an MDP-based all-in-one adhesive on the efficacy of smear layer removal and on dentin bonding performance.

Teshima, Masahiro

2018 Band 37, Heft 4, Seite(n) 685–692

Abstract: The effects of the water concentration in an experimental 10-methacryloyloxydecyl dihydrogen phosphate (MDP)-based all-in-one (EX) adhesive were examined on the ability of MDP to remove the smear layer from the ground dentin surface and on the dentin ... ...

Abstract	The effects of the water concentration in an experimental 10-methacryloyloxydecyl dihydrogen phosphate (MDP)-based all-in-one (EX) adhesive were examined on the ability of MDP to remove the smear layer from the ground dentin surface and on the dentin bonding performance. Four types of EX adhesives were prepared by varying the amount of water (46.6, 93.2, 149.8 and 208.1 mg/g), but the MDP concentration was kept a constant at 49.9 mg/g. Scanning electron microscopy and bond strength measurements were performed on the dentin surface demineralized by each EX adhesive. Increased amount of water in the EX adhesive increased the ability of MDP to remove the smear layer. However, the solubilization of the smear layer into the EX adhesive decreased the dentin bond strength. The water concentration in the EX adhesive affected the efficacies of smear layer removal and dentin bonding performance more strongly than the pH value of the EX adhesive.
Mesh-Begriff(e)	Dental Bonding/methods ; Dental Stress Analysis ; Dentin/chemistry ; Dentin-Bonding Agents/chemistry ; Hydrogen-Ion Concentration ; Methacrylates/chemistry ; Microscopy, Electron, Scanning ; Shear Strength ; Smear Layer ; Surface Properties ; Water/chemistry
Chemische Substanzen	Dentin-Bonding Agents ; Methacrylates ; Water (059QF0KO0R) ; methacryloyloxydecyl dihydrogen phosphate (85590-00-7)
Sprache	Englisch
Erscheinungsdatum	2018-05-02
Erscheinungsland	Japan
Dokumenttyp	Journal Article
ZDB-ID	605650-7
ISSN	1881-1361 ; 0287-4547
ISSN (online)	1881-1361
ISSN	0287-4547
DOI	10.4012/dmj.2017-291
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Immediate effects of standing unstable board intervention on the non-paralyzed leg on sitting balance in severe hemiplegia: a randomized controlled trial.

Nagai, Koki / Amimoto, Kazu / Teshima, Masato / Ito, Takeshi / Nariya, Honoka / Ueno, Ryuji / Ikeda, Yumi

Topics in stroke rehabilitation

2024 Band 31, Heft 5, Seite(n) 446–456

Abstract: Background: Unstable board intervention for patients with stroke improves sitting balance and trunk function. However, because patients with severe stroke are at high risk of falling, it is mostly adapted in mild cases.: Objective: We aimed to ... ...

Abstract	Background: Unstable board intervention for patients with stroke improves sitting balance and trunk function. However, because patients with severe stroke are at high risk of falling, it is mostly adapted in mild cases. Objective: We aimed to examine the effect of standing unstable board intervention for the non-paralyzed lower limbs on sitting balance in patients with hemiplegia. Methods: The participants were 42 patients with stroke who were randomly assigned to a control or intervention group. In the intervention group, the non-paralyzed leg was placed on an unstable board, and the patient wore a knee-ankle-foot orthosis on the paralyzed side and practiced standing and weight-bearing exercises on the unstable board for 3 days. The outcomes were the angle of righting reaction of the neck, trunk, and both lower legs and the movement distance of the center of pressure of the righting reaction from lateral tilted sitting. Results: In the intervention group, the righting reaction angle of the trunk to the paralyzed and non-paralyzed sides and the movement distance of the center of pressure were increased significantly after the unstable board intervention. Conclusion: The standing unstable board intervention for the non-paralyzed lower limb increased sensory input to the non-paralyzed side of the trunk weight-bearing on the lower limb of the paralyzed side. The increase in the righting reaction angle and the movement distance of the center of pressure contributed to improved sitting balance.
Mesh-Begriff(e)	Humans ; Hemiplegia/rehabilitation ; Hemiplegia/physiopathology ; Hemiplegia/etiology ; Male ; Female ; Postural Balance/physiology ; Middle Aged ; Aged ; Sitting Position ; Stroke Rehabilitation/methods ; Stroke/complications ; Stroke/physiopathology ; Exercise Therapy/methods ; Orthotic Devices ; Leg/physiopathology
Sprache	Englisch
Erscheinungsdatum	2024-01-15
Erscheinungsland	England
Dokumenttyp	Journal Article ; Randomized Controlled Trial
ZDB-ID	1213112-x
ISSN	1945-5119 ; 1074-9357
ISSN (online)	1945-5119
ISSN	1074-9357
DOI	10.1080/10749357.2024.2302730
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: A magnesium transporter is involved in the cesium ion resistance of the high-concentration cesium ion-resistant bacterium

Ishida, Yoshiki / Koretsune, Takahiro / Ishiuchi, Eri / Teshima, Miyu / Ito, Masahiro

Frontiers in microbiology

2023 Band 14, Seite(n) 1136514

Abstract: Cesium ion ( ... ...

Abstract	Cesium ion (Cs
Sprache	Englisch
Erscheinungsdatum	2023-02-23
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2023.1136514
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: [A Case of Spinal Cord Metastasis from Breast Cancer Successfully Treated with Trastuzumab Deruxtecan].

Teshima, Marino / Itagaki, Tomoko / Kajitani, Keiko / Ohara, Masahiro / Kawabuchi, Yosiharu

Gan to kagaku ryoho. Cancer & chemotherapy

2023 Band 50, Heft 6, Seite(n) 719–722

Abstract: Objective: Intramedullary spinal cord metastases(ISCM)are very rare in patients with breast cancer and have a poor prognosis with no established treatment. We report a case of ISCM in a patient with HER2-positive breast cancer who was successfully ... ...

Abstract	Objective: Intramedullary spinal cord metastases(ISCM)are very rare in patients with breast cancer and have a poor prognosis with no established treatment. We report a case of ISCM in a patient with HER2-positive breast cancer who was successfully treated with a novel anti-HER2 agent, trastuzumab deruxtecan(T-DXd, ENHERTU®). Case: The patient was a 44- year-old woman who underwent surgery for right breast cancer. T-DXd was introduced as the fourth-line metastatic treatment for multiple metastases, including liver, bone, pituitary, brain, and spinal cord metastases. Hematologic and non- hematologic toxicities did not occur during the treatment with T-DXd. T-DXd could be administered continuously for 25 cycles, and symptoms such as numbness in the left lower limb were controlled without progression of the brain and spinal cord, although T-DXd-induced interstitial lung disease was a concern. Discussion: ISCM is a rare metastatic lesion that is difficult to treat with chemotherapy due to the blood-brain barrier (BBB), and there is no established treatment for ISCM. T-DXd has shown promising results in previous clinical trials, including in patients with central nerve system (CNS) metastases, and is expected to be a good treatment option for CNS metastases in clinical practice. Conclusion: This successful case of T-DXd for ISCM suggests that T-DXd is an effective treatment option for patients with breast cancer and CNS metastases.
Mesh-Begriff(e)	Female ; Humans ; Adult ; Breast Neoplasms/drug therapy ; Trastuzumab ; Immunoconjugates ; Spinal Cord Neoplasms/drug therapy ; Spinal Cord Neoplasms/surgery ; Neoplasms, Second Primary
Chemische Substanzen	trastuzumab deruxtecan (5384HK7574) ; Trastuzumab (P188ANX8CK) ; Immunoconjugates
Sprache	Japanisch
Erscheinungsdatum	2023-06-15
Erscheinungsland	Japan
Dokumenttyp	Case Reports ; English Abstract ; Journal Article
ZDB-ID	604842-0
ISSN	0385-0684
ISSN	0385-0684
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Cell-free enzyme cascades - application and transition from development to industrial implementation.

Teshima, Mariko / Willers, Vivian Pascal / Sieber, Volker

Current opinion in biotechnology

2022 Band 79, Seite(n) 102868

Abstract: In the vision to realize a circular economy aiming for net carbon neutrality or even negativity, cell-free bioconversion of sustainable and renewable resources emerged as a promising strategy. The potential of in vitro systems is enormous, delivering ... ...

Abstract	In the vision to realize a circular economy aiming for net carbon neutrality or even negativity, cell-free bioconversion of sustainable and renewable resources emerged as a promising strategy. The potential of in vitro systems is enormous, delivering technological, ecological, and ethical added values. Innovative concepts arose in cell-free enzymatic conversions to reduce process waste production and preserve fossil resources, as well as to redirect and assimilate released industrial pollutions back into the production cycle again. However, the great challenge in the near future will be the jump from a concept to an industrial application. The transition process in industrial implementation also requires economic aspects such as productivity, scalability, and cost-effectiveness. Here, we briefly review the latest proof-of-concept cascades using carbon dioxide and other C1 or lignocellulose-derived chemicals as blueprints to efficiently recycle greenhouse gases, as well as cutting-edge technologies to maturate these concepts to industrial pilot plants.
Mesh-Begriff(e)	Carbon Dioxide ; Cell-Free System ; Enzymes/chemistry ; Biotechnology/trends
Chemische Substanzen	Carbon Dioxide (142M471B3J) ; Enzymes
Sprache	Englisch
Erscheinungsdatum	2022-12-21
Erscheinungsland	England
Dokumenttyp	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	1052045-4
ISSN	1879-0429 ; 0958-1669
ISSN (online)	1879-0429
ISSN	0958-1669
DOI	10.1016/j.copbio.2022.102868
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: A case of pancreatic adenosquamous cell carcinoma with a pseudocyst following curative surgery.

Kitasaki, Nao / Abe, Tomoyuki / Inoue, Masashi / Teshima, Marino / Nakagawa, Masataka / Kochi, Masatoshi / Hotta, Ryuichi / Toyota, Kazuhiro

Surgical case reports

2024 Band 10, Heft 1, Seite(n) 74

Abstract: Background: Pancreatic adenosquamous cell carcinoma (PASC) is a relatively rare histological type of pancreatic malignancy, and preoperative diagnosis is difficult because of its rarity. PASC accounts for 1-4% of all pancreatic cancers, and even after ... ...

Abstract	Background: Pancreatic adenosquamous cell carcinoma (PASC) is a relatively rare histological type of pancreatic malignancy, and preoperative diagnosis is difficult because of its rarity. PASC accounts for 1-4% of all pancreatic cancers, and even after curative surgery, its prognosis is poorer than that of ordinary pancreatic adenocarcinoma. Pathologically, it shows glandular and squamous differentiation of cells. Complete resection is the only method to achieve a good long-term prognosis, and an increasing doubling time of PASC is considered to indicate early recurrence after surgery. Here, we report a rare case of PASC with an infected pancreatic cyst that was difficult to treat, along with a review of the literature. Case presentation: A woman in her 80s with a history of breast cancer presented with pericardial pain. Computed tomography revealed a 20-mm hypovascular tumor in the body of the pancreas and a 27-mm pseudocyst. Endoscopic retrograde cholangiopancreatography showed a severe main pancreatic duct stenosis in the body of the pancreas that made cannulation impossible, and contrast media extravasation was due to pancreatic duct disruption in the pancreatic tail. Endoscopic fine-needle aspiration revealed that the tumor was a PASC. Because the patient had an infected pancreatic cyst, central intravenous nutrition and antibiotics were administered, which stabilized her general condition. She was diagnosed with resectable PASC and underwent distal pancreatectomy with lymphadenectomy. The postoperative course was uneventful. Immunohistochemical analysis of the resected specimen confirmed T2N0M0 stage IB. Systemic adjuvant chemotherapy with S-1 is ongoing. Conclusion: Appropriate preoperative management and preoperative accurate staging (T2N0M0 stage IB) of PASC with curative surgery can ensure predictable outcomes.
Sprache	Englisch
Erscheinungsdatum	2024-04-01
Erscheinungsland	Germany
Dokumenttyp	Journal Article
ZDB-ID	2809613-7
ISSN	2198-7793
ISSN	2198-7793
DOI	10.1186/s40792-024-01868-z
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Development of a Highly Selective NAD

Teshima, Mariko / Sutiono, Samuel / Döring, Manuel / Beer, Barbara / Boden, Mikael / Schenk, Gerhard / Sieber, Volker

ChemSusChem

2023 Band 17, Heft 4, Seite(n) e202301132

Abstract: Anthropogenic climate change has been caused by over-exploitation of fossil fuels and ... ...

Abstract	Anthropogenic climate change has been caused by over-exploitation of fossil fuels and CO
Mesh-Begriff(e)	Glyceraldehyde/metabolism ; NAD/metabolism ; Pyruvic Acid ; Ethanol ; Oxidoreductases
Chemische Substanzen	Glyceraldehyde (367-47-5) ; NAD (0U46U6E8UK) ; Pyruvic Acid (8558G7RUTR) ; Ethanol (3K9958V90M) ; Oxidoreductases (EC 1.-)
Sprache	Englisch
Erscheinungsdatum	2023-11-16
Erscheinungsland	Germany
Dokumenttyp	Journal Article
ISSN	1864-564X
ISSN (online)	1864-564X
DOI	10.1002/cssc.202301132
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Enabling the Direct Enzymatic Dehydration of d-Glycerate to Pyruvate as the Key Step in Synthetic Enzyme Cascades Used in the Cell-Free Production of Fine Chemicals

Sutiono, S. / Teshima, M. / Beer, B. / Schenk, G. / Sieber, V.

2020

Abstract: S.3110-3118 ... A high degree of dependence on fossil fuels is one of the major problems faced by modern societies. d-Glucose and glycerol have emerged in recent years as prospective replacements for fossil fuels used in the production of high-value ... ...

Abstract	S.3110-3118 A high degree of dependence on fossil fuels is one of the major problems faced by modern societies. d-Glucose and glycerol have emerged in recent years as prospective replacements for fossil fuels used in the production of high-value chemicals, and cell-free bioproduction routes are expected to play a crucial role in such processes. Recently, several synthetic cascades used for the cell-free biotransformations of d-glucose and glycerol to pyruvate and beyond have been described. However, these were limited by the very slow dehydration step of d-glycerate to pyruvate catalyzed by a dehydratase from Sulfolobus solfataricus (SsDHAD), making this step by far the major bottleneck. By combining the vast number of available genomes with a sequence-based discovery approach, we have identified signature sequences leading to the discovery of two distinct classes of dehydratases which exhibit promising activity and total turnover number (TTN) toward d-glycerate. In particular, the dehydratase from Paralcaligenes ureilyticus (PuDHT) demonstrated >100-fold higher activity and TTN for d-glycerate in comparison to SsDHAD. In addition, PuDHT showed exceptionally high activity and TTN toward d-gluconate. The replacement of SsDHAD by PuDHT in our model cascade from d-glucose to ethanol enhanced the production rate 10-fold, reaching a 92% theoretical yield at 50 °C. PuDHT was also suitable for the conversion of glycerol to pyruvate at ambient temperature, leading to a >5-fold improvement in production rate in comparison to the system utilizing SsDHAD at 50 °C and attaining 97% of the theoretical yield. PuDHT was also compatible when crude glycerol was used as the substrate, and it no longer caused a bottleneck in the enzymatic cascade. 10 Nr.5
Schlagwörter	660 ; 610 ; 620
Thema/Rubrik (Code)	660
Sprache	Englisch
Erscheinungsland	de
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: A study for the evaluation of a safety education program me for nursing students: discussions using the QSEN safety competencies.

Watanabe, Yaeko / Claus, Sachiko / Nakagawa, Taiya / Yasunami, Shigeko / Teshima, Megumi

Journal of research in nursing : JRN

2021 Band 26, Heft 1-2, Seite(n) 97–115

Abstract: Background: To respond to calls for improvements in nursing education in Japan, a group of faculties of a baccalaureate nursing programme has made an initial attempt to incorporate quality and safety education for nurses safety competency into three ... ...

Abstract	Background: To respond to calls for improvements in nursing education in Japan, a group of faculties of a baccalaureate nursing programme has made an initial attempt to incorporate quality and safety education for nurses safety competency into three related courses, two sophomore level courses and one senior level course. Aims: To evaluate the learning experiences in a senior level course on medical safety in order to identify learning outcomes in terms of areas of strengths and areas for further improvements of the course and a system-wide implementation of quality and safety education for nurses competencies in the future. Methods: Fourteen students who met the criteria had volunteered to participate in one of the two 40-minute focus group interviews. During the interviews, participants were asked questions as to what they have learned and how they may use that knowledge in the future. The sessions were tape recorded, the data were transcribed and analysed using the content analysis method according to Berelson. Results: Eight categories of learning related to medical safety were identified, including awareness of own risks for errors and plans to reduce such risks. These categories of learning were thought to have achieved the level equal to 75% of quality and safety education for nurses knowledge, skills and attitudes items. Conclusions: The current content and methods for this course identified strengths to be continued, with some areas of improvement for the future for further adoption of quality and safety education for nurses competencies into the entire curriculum.
Sprache	Englisch
Erscheinungsdatum	2021-03-22
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	2173772-1
ISSN	1744-988X ; 1744-9871
ISSN (online)	1744-988X
ISSN	1744-9871
DOI	10.1177/1744987121994859
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Intraoperative quantitative assessment of parathyroid blood flow during total thyroidectomy using indocyanine green fluorescence imaging - surgical strategies for preserving the function of parathyroid glands.

Iritani, Keisuke / Teshima, Masanori / Shimoda, Hikari / Shinomiya, Hirotaka / Otsuki, Naoki / Nibu, Ken-Ichi

Laryngoscope investigative otolaryngology

2022 Band 7, Heft 4, Seite(n) 1251–1258

Sprache	Englisch
Erscheinungsdatum	2022-07-18
Erscheinungsland	United States
Dokumenttyp	Journal Article
ISSN	2378-8038
ISSN	2378-8038
DOI	10.1002/lio2.868
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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