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  1. Article: The Relevance of Thiamine Evaluation in a Practical Setting

    Pacei, Federico / Tesone, Antonella / Laudi, Nazzareno / Laudi, Emanuele / Cretti, Anna / Pnini, Shira / Varesco, Fabio / Colombo, Chiara

    Nutrients. 2020 Sept. 13, v. 12, no. 9

    2020  

    Abstract: Thiamine is a crucial cofactor involved in the maintenance of carbohydrate metabolism and participates in multiple cellular metabolic processes. Although thiamine can be obtained from various food sources, some common food groups are deficient in ... ...

    Abstract Thiamine is a crucial cofactor involved in the maintenance of carbohydrate metabolism and participates in multiple cellular metabolic processes. Although thiamine can be obtained from various food sources, some common food groups are deficient in thiamine, and it can be denatured by high temperature and pH. Additionally, different drugs can alter thiamine metabolism. In addition, the half-life of thiamine in the body is between 1 and 3 weeks. All these factors could provide an explanation for the relatively short period needed to develop thiamine deficiency and observe the consequent clinical symptoms. Thiamine deficiency could lead to neurological and cardiological problems. These clinical conditions could be severe or even fatal. Marginal deficiency too may promote weaker symptoms that might be overlooked. Patients undergoing upper gastrointestinal or pancreatic surgery could have or develop thiamine deficiency for many different reasons. To achieve the best outcome for these patients, we strongly recommend the execution of both an adequate preoperative nutritional assessment, which includes thiamine evaluation, and a close nutritional follow up to avoid a nutrient deficit in the postoperative period.
    Keywords carbohydrate metabolism ; gastrointestinal system ; half life ; nutrition assessment ; pH ; surgery ; temperature ; thiamin
    Language English
    Dates of publication 2020-0913
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    Note NAL-light
    ZDB-ID 2518386-2
    ISSN 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu12092810
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: The Relevance of Thiamine Evaluation in a Practical Setting.

    Pacei, Federico / Tesone, Antonella / Laudi, Nazzareno / Laudi, Emanuele / Cretti, Anna / Pnini, Shira / Varesco, Fabio / Colombo, Chiara

    Nutrients

    2020  Volume 12, Issue 9

    Abstract: Thiamine is a crucial cofactor involved in the maintenance of carbohydrate metabolism and participates in multiple cellular metabolic processes. Although thiamine can be obtained from various food sources, some common food groups are deficient in ... ...

    Abstract Thiamine is a crucial cofactor involved in the maintenance of carbohydrate metabolism and participates in multiple cellular metabolic processes. Although thiamine can be obtained from various food sources, some common food groups are deficient in thiamine, and it can be denatured by high temperature and pH. Additionally, different drugs can alter thiamine metabolism. In addition, the half-life of thiamine in the body is between 1 and 3 weeks. All these factors could provide an explanation for the relatively short period needed to develop thiamine deficiency and observe the consequent clinical symptoms. Thiamine deficiency could lead to neurological and cardiological problems. These clinical conditions could be severe or even fatal. Marginal deficiency too may promote weaker symptoms that might be overlooked. Patients undergoing upper gastrointestinal or pancreatic surgery could have or develop thiamine deficiency for many different reasons. To achieve the best outcome for these patients, we strongly recommend the execution of both an adequate preoperative nutritional assessment, which includes thiamine evaluation, and a close nutritional follow up to avoid a nutrient deficit in the postoperative period.
    MeSH term(s) Digestive System Surgical Procedures/adverse effects ; Humans ; Nutritional Status ; Thiamine/blood ; Thiamine Deficiency/blood ; Thiamine Deficiency/etiology ; Thiamine Deficiency/prevention & control
    Chemical Substances Thiamine (X66NSO3N35)
    Language English
    Publishing date 2020-09-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu12092810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Prevalence rate of Metabolic Syndrome in a group of light and heavy smokers.

    Cena, Hellas / Tesone, Antonella / Niniano, Rosanna / Cerveri, Isa / Roggi, Carla / Turconi, Giovanna

    Diabetology & metabolic syndrome

    2013  Volume 5, Issue 1, Page(s) 28

    Abstract: Background: Smoking is an important cause of morbidity and mortality worldwide. It is widely accepted as a major risk factor for metabolic and cardiovascular disease. Smoking reduces insulin sensitivity or induces insulin resistance and enhances ... ...

    Abstract Background: Smoking is an important cause of morbidity and mortality worldwide. It is widely accepted as a major risk factor for metabolic and cardiovascular disease. Smoking reduces insulin sensitivity or induces insulin resistance and enhances cardiovascular risk factors such as elevated plasma triglycerides, decreases high-density lipoprotein cholesterol and causes hyperglycemia. Several studies show that smoking is associated with metabolic abnormalities and increases the risk of Metabolic Syndrome. The aim of this study was to estimate the prevalence of the metabolic syndrome in a group of light and heavy smokers, wishing to give up smoking.
    Methods: In this cross-sectional study all the enrolled subjects voluntary joined the smoking cessation program held by the Respiratory Pathophysiology Unit of San Matteo Hospital, Pavia, Northern Italy.All the subjects enrolled were former smokers from at least 10 years and had no cancer or psychiatric disorders, nor history of diabetes or CVD or coronary artery disease and were not on any medication.
    Results: The subjects smoke 32.3 ± 16.5 mean Pack Years. The prevalence of the metabolic syndrome is 52.1%: 57.3% and 44.9% for males and females respectively. Analysing the smoking habit influence on the IDF criteria for the metabolic syndrome diagnosis we found that all the variables show an increasing trend from light to heavy smokers, except for HDL cholesterol. A statistical significant correlation among Pack Years and waist circumference (R = 0.48, p < 0.0001), Systolic Blood Pressure (R = 0.18, p < 0.05), fasting plasma glucose (R = 0.19, p < 0.005) and HDL cholesterol (R = -0.26, p = 0.0005) has been observed.
    Conclusions: Currently smoking subjects are at high risk of developing the metabolic syndrome.Therapeutic lifestyle changes, including smoking cessation are a desirable Public health goal and should successfully be implemented in clinical practice at any age.
    Language English
    Publishing date 2013-05-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2518786-7
    ISSN 1758-5996
    ISSN 1758-5996
    DOI 10.1186/1758-5996-5-28
    Database MEDical Literature Analysis and Retrieval System OnLINE

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