Article: Advances in CMV Management: A Single Center Real-Life Experience.
Frontiers in cell and developmental biology
2020 Volume 8, Page(s) 534268
Abstract: CMV infection is a major challenge in allogeneic stem cell transplantation (allo-SCT). The changing landscape in CMV management includes the introduction of letermovir in prophylaxis of high-risk patients and the source of CMV DNA monitoring (plasma-PL ... ...
| Abstract | CMV infection is a major challenge in allogeneic stem cell transplantation (allo-SCT). The changing landscape in CMV management includes the introduction of letermovir in prophylaxis of high-risk patients and the source of CMV DNA monitoring (plasma-PL vs. whole blood-WB), for pre-emptive therapy (PET) initiation. We report here how our real-life experience in CMV management evolved, following letermovir registration. We focus on: (i) the effects of systematic use of letermovir for CMV prophylaxis in high-risk patients, (ii) the results of a longitudinal comparison of CMV DNAemia monitoring in PL and WB. From December 2018 to April 2020, 60 allo-SCTs have been performed in our center (LET |
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| Language | English |
| Publishing date | 2020-10-27 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2737824-X |
| ISSN | 2296-634X |
| ISSN | 2296-634X |
| DOI | 10.3389/fcell.2020.534268 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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