LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article ; Online: Parthenium hysterophorus derived nanostructures as an efficient carbocatalyst for the electrochemical sensing of mercury(II) ions.

    Sharma, Ritika / Rana, Dharmender Singh / Gupta, Neeraj / Thakur, Sourbh / Thakur, Kamal Kishor / Singh, Dilbag

    Chemosphere

    2024  Volume 354, Page(s) 141591

    Abstract: The sustainable utilization of resources motivate us to create eco-friendly processes for synthesizing novel carbon nanomaterials from waste biomass by minimizing chemical usage and reducing energy demands. By keeping sustainability as a prime focus in ... ...

    Abstract The sustainable utilization of resources motivate us to create eco-friendly processes for synthesizing novel carbon nanomaterials from waste biomass by minimizing chemical usage and reducing energy demands. By keeping sustainability as a prime focus in the present work, we have made the effective management of Parthenium weeds by converting them into carbon-based nanomaterial through hydrothermal treatment followed by heating in a tube furnace under the nitrogen atmosphere. The XPS studies confirm the natural presence of nitrogen and oxygen-containing functional groups in the biomass-derived carbon. The nanostructure has adopted a layered two-dimensional structure, clearly indicated through HRTEM images. Further, the nanomaterials are analyzed for their ability towards the electrochemical detection of mercury, with a detection limit of 6.17 μM, while the limit of quantification and sensitivity was found to be 18.7 μM and 0.4723 μM μA
    MeSH term(s) Mercury ; Parthenium hysterophorus ; Biosensing Techniques/methods ; Nanostructures/chemistry ; Carbon/chemistry ; Ions ; Nitrogen/chemistry ; Oxygen
    Chemical Substances Mercury (FXS1BY2PGL) ; Carbon (7440-44-0) ; Ions ; Nitrogen (N762921K75) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141591
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2540: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: A Review on Synthesis of 2-Dimensional Mn+1X (MXene) materials

    Sahil / Dahiya Hanny / Thakur Kamal Kishor

    E3S Web of Conferences, Vol 309, p

    2021  Volume 01062

    Abstract: The sequence of 2D transition metal carbides, carbonitrides, and nitrides has gained a lot of interest since the discovery of Ti3C2. About thirty new MXene compounds have been identified, with eight different MXene synthesis methods. The presence of ... ...

    Abstract The sequence of 2D transition metal carbides, carbonitrides, and nitrides has gained a lot of interest since the discovery of Ti3C2. About thirty new MXene compounds have been identified, with eight different MXene synthesis methods. The presence of surface terminations such as hydroxyl, oxygen, fluorine, or chlorine in the materials described thus far indicates strong hydrophilicity as well as metallic conductivity MXenes are becoming increasingly popular due to their diverse chemistry, which has sparked a surge in academic interest. We will study and examine the many methods of fabricating MXenes in this review, which will cover everything from MAX phase etching to exfoliation, as well as the best approach to synthesise them and their most current applications.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article: Comparative Drug Release Investigations for Diclofenac Sodium Drug (DS) by Chitosan-Based Grafted and Crosslinked Copolymers.

    Chopra, Lalita / Thakur, Kamal Kishor / Chohan, Jasgurpreet Singh / Sharma, Shubham / Ilyas, R A / Asyraf, M R M / Zakaria, S Z S

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 7

    Abstract: The hydrogels responding to pH synthesized by graft copolymerization only and then concurrent grafting and crosslinking of monomer N-isopropyl acrylamide (NIPAAM) and binary comonomers acrylamide, acrylic acid and acrylonitrile (AAm, AA and AN) onto ... ...

    Abstract The hydrogels responding to pH synthesized by graft copolymerization only and then concurrent grafting and crosslinking of monomer N-isopropyl acrylamide (NIPAAM) and binary comonomers acrylamide, acrylic acid and acrylonitrile (AAm, AA and AN) onto chitosan support were explored for the percent upload and release study for anti-inflammatory diclofenac sodium drug (DS), w.r.t. time and pH. Diclofenac sodium DS was seized in polymeric matrices by the equilibration process. The crosslinked-graft copolymers showed the highest percent uptake than graft copolymers (without crosslinker) and chitosan itself. The sustainable release of the loaded drug was studied with respect to time at pH 2.2, 7.0, 7.4 and 9.4. Among graft copolymers (without crosslinking), Chit-g-polymer (NIPAAM-co-AA) and Chit-g-polymer (NIPAAM-co-AN) exhibited worthy results for sustainable drug deliverance, whereas Crosslink-Chit-g-polymer (NIPAAM-co-AA) and Crosslink-Chit-g-polymer (NIPAAM-co-AAm) presented the best results for controlled/sustained release of diclofenac sodium DS with 93.86 % and 96.30 % percent release, respectively, in 6 h contact time. Therefore, the grafted and the crosslinked graft copolymers of the chitosan showed excellent delivery devices for the DS with sustainable/prolonged release in response to pH. Drug release kinetics was studied using Fick’s law. The kinetic study revealed that polymeric matrices showed the value of n as n > 1.0, hence drug release took place by non-Fickian diffusion. Hence, the present novel findings showed the multidirectional drug release rate. The morphological changes due to interwoven network structure of the crosslinked are evident by the Scanning electron microscopy (SEM) analysis.
    Language English
    Publishing date 2022-03-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15072404
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Preparation and characterization of pH-responsive guar gum microspheres.

    Sharma, Shitika / Kaur, Jasvinder / Sharma, Gaurav / Thakur, Kamal Kishor / Chauhan, Ghanshyam S / Chauhan, Kalpana

    International journal of biological macromolecules

    2013  Volume 62, Page(s) 636–641

    Abstract: Guar gum, being the natural polymer is renewable, nontoxic, biocompatible and biodegradable. Therefore, it is the perfect material to formulate particulates or microspheres for potential applications in pharmaceutical. The formulation of material in nano/ ...

    Abstract Guar gum, being the natural polymer is renewable, nontoxic, biocompatible and biodegradable. Therefore, it is the perfect material to formulate particulates or microspheres for potential applications in pharmaceutical. The formulation of material in nano/microsphere scale offers new rich in application potential. In view of that, novel biodegradable and pH-sensitive hydrogels composed of pH-sensitive methacrylic acid (MAc) and a biodegradable guar gum were synthesized by grafting reactions. Water-in-oil (w/o) emulsion method was used to direct the pH-sensitive material in microspheres shape using bi-functional glutaraldehyde (GA) as crosslinker. The synthesized microspheres were characterized by FTIR and SEM (different magnification). The swelling ratios of hydrogels in buffer solutions showed a pH-dependent profile at physiological pH. In vitro release data was analyzed using Fick's law, which indicated swelling controlled super case II transport of BSA through the synthesized microspheres. Therefore, in conclusion, as ascertained from the results the introduction of -COOH moieties along the guar gum chain drastically increases the end-use performance due to pH-sensitivity.
    MeSH term(s) Cross-Linking Reagents ; Drug Carriers/chemistry ; Drug Delivery Systems/methods ; Galactans/chemistry ; Galactans/ultrastructure ; Glutaral ; Hydrogels ; Hydrogen-Ion Concentration ; Mannans/chemistry ; Mannans/ultrastructure ; Methacrylates/chemistry ; Microspheres ; Molecular Structure ; Plant Gums/chemistry ; Spectroscopy, Fourier Transform Infrared
    Chemical Substances Cross-Linking Reagents ; Drug Carriers ; Galactans ; Hydrogels ; Mannans ; Methacrylates ; Plant Gums ; methacrylic acid (1CS02G8656) ; guar gum (E89I1637KE) ; Glutaral (T3C89M417N)
    Language English
    Publishing date 2013-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2013.09.045
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2374: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Uneven spread of cis- and trans-editing aminoacyl-tRNA synthetase domains within translational compartments of P. falciparum.

    Khan, Sameena / Sharma, Arvind / Jamwal, Abhishek / Sharma, Vinay / Pole, Anil Kumar / Thakur, Kamal Kishor / Sharma, Amit

    Scientific reports

    2011  Volume 1, Page(s) 188

    Abstract: Accuracy of aminoacylation is dependent on maintaining fidelity during attachment of amino acids to cognate tRNAs. Cis- and trans-editing protein factors impose quality control during protein translation, and 8 of 36 Plasmodium falciparum aminoacyl-tRNA ... ...

    Abstract Accuracy of aminoacylation is dependent on maintaining fidelity during attachment of amino acids to cognate tRNAs. Cis- and trans-editing protein factors impose quality control during protein translation, and 8 of 36 Plasmodium falciparum aminoacyl-tRNA synthetase (aaRS) assemblies contain canonical putative editing modules. Based on expression and localization profiles of these 8 aaRSs, we propose an asymmetric distribution between the parasite cytoplasm and its apicoplast of putative editing-domain containing aaRSs. We also show that the single copy alanyl- and threonyl-tRNA synthetases are dually targeted to parasite cytoplasm and apicoplast. This bipolar presence of two unique synthetases presents opportunity for inhibitor targeting their aminoacylation and editing activities in twin parasite compartments. We used this approach to identify specific inhibitors against the alanyl- and threonyl-tRNA synthetases. Further development of such inhibitors may lead to anti-parasitics which simultaneously block protein translation in two key parasite organelles, a strategy of wider applicability for pathogen control.
    MeSH term(s) Amino Acyl-tRNA Synthetases/chemistry ; Animals ; Antiparasitic Agents/pharmacology ; Cloning, Molecular ; Cytoplasm/enzymology ; Fibroblasts/cytology ; Gene Expression Regulation ; Gene Expression Regulation, Enzymologic ; Green Fluorescent Proteins/metabolism ; HeLa Cells ; Humans ; Mice ; Plasmodium falciparum/enzymology ; Protein Structure, Tertiary ; Protozoan Proteins/chemistry ; Threonine-tRNA Ligase/chemistry
    Chemical Substances Antiparasitic Agents ; Protozoan Proteins ; Green Fluorescent Proteins (147336-22-9) ; Amino Acyl-tRNA Synthetases (EC 6.1.1.-) ; Threonine-tRNA Ligase (EC 6.1.1.3)
    Language English
    Publishing date 2011-12-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/srep00188
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Preparation and characterization of pH-responsive guar gum microspheres

    Sharma, Shitika / Kaur, Jasvinder / Sharma, Gaurav / Thakur, Kamal Kishor / Chauhan, Ghanshyam S. / Chauhan, Kalpana

    International journal of biological macromolecules

    Volume v. 62

    Abstract: Guar gum, being the natural polymer is renewable, nontoxic, biocompatible and biodegradable. Therefore, it is the perfect material to formulate particulates or microspheres for potential applications in pharmaceutical. The formulation of material in nano/ ...

    Abstract Guar gum, being the natural polymer is renewable, nontoxic, biocompatible and biodegradable. Therefore, it is the perfect material to formulate particulates or microspheres for potential applications in pharmaceutical. The formulation of material in nano/microsphere scale offers new rich in application potential. In view of that, novel biodegradable and pH-sensitive hydrogels composed of pH-sensitive methacrylic acid (MAc) and a biodegradable guar gum were synthesized by grafting reactions. Water-in-oil (w/o) emulsion method was used to direct the pH-sensitive material in microspheres shape using bi-functional glutaraldehyde (GA) as crosslinker. The synthesized microspheres were characterized by FTIR and SEM (different magnification). The swelling ratios of hydrogels in buffer solutions showed a pH-dependent profile at physiological pH. In vitro release data was analyzed using Fick's law, which indicated swelling controlled super case II transport of BSA through the synthesized microspheres. Therefore, in conclusion, as ascertained from the results the introduction of COOH moieties along the guar gum chain drastically increases the end-use performance due to pH-sensitivity.
    Keywords glutaraldehyde ; nanomaterials ; guar gum ; emulsions ; biodegradability ; scanning electron microscopy ; polymers ; pH ; hydrocolloids ; particulates ; Fourier transform infrared spectroscopy
    Language English
    Document type Article
    ISSN 0141-8130
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top