Article ; Online: Hepatosplenic Alpha-Beta T-Cell Lymphoma: A Challenging Diagnostic Entity.
2024 Volume 13, Issue 1-2, Page(s) 29–33
Abstract: Hepatosplenic T-cell lymphoma (HSTCL) is rare and clinically very aggressive T-cell lymphoma. The majority of cases harbor γδ T-cell receptors (TCRs); however, in some even rarer cases, tumor cells harbor αβ TCR. Recent studies suggest that αβ cases may ... ...
| Abstract | Hepatosplenic T-cell lymphoma (HSTCL) is rare and clinically very aggressive T-cell lymphoma. The majority of cases harbor γδ T-cell receptors (TCRs); however, in some even rarer cases, tumor cells harbor αβ TCR. Recent studies suggest that αβ cases may have distinct morphological characteristics and demonstrate an even more aggressive course. In this case report, we demonstrated that in line with previous findings, αβ case of HSTCL had hemolytic presentation, demonstrated a very aggressive clinical course, and was unrelated to immunosuppression. Morphologically, tumor cells demonstrated diffuse growth pattern, blastoid morphology, and were CD8 |
|---|---|
| Language | English |
| Publishing date | 2024-04-09 |
| Publishing country | Canada |
| Document type | Case Reports |
| ZDB-ID | 2662519-2 |
| ISSN | 1927-1220 ; 1927-1220 |
| ISSN (online) | 1927-1220 |
| ISSN | 1927-1220 |
| DOI | 10.14740/jh1203 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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