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  1. Article ; Online: Acquisition of Host Cytosolic Protein by Toxoplasma gondii Bradyzoites.

    Kannan, Geetha / Thaprawat, Pariyamon / Schultz, Tracey L / Carruthers, Vern B

    mSphere

    2021  Volume 6, Issue 1

    Abstract: Toxoplasma ... ...

    Abstract Toxoplasma gondii
    MeSH term(s) Animals ; CHO Cells ; Cricetulus ; Cytosol/metabolism ; Doxycycline/pharmacology ; Host-Parasite Interactions ; Luminescent Proteins/metabolism ; Male ; Mice ; Mice, Inbred CBA ; Toxoplasma/metabolism ; Red Fluorescent Protein
    Chemical Substances Luminescent Proteins ; Doxycycline (N12000U13O)
    Language English
    Publishing date 2021-01-27
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/mSphere.00934-20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Status of hospital infection prevention practices in Thailand in the era of COVID-19: Results from a national survey.

    Thaprawat, Pariyamon / Greene, Michael Todd / Saint, Sanjay / Kasatpibal, Nongyao / Fowler, Karen E / Apisarnthanarak, Anucha

    American journal of infection control

    2022  Volume 50, Issue 9, Page(s) 975–980

    Abstract: Background: A 2014 study assessed infection prevention (IP) practices in Thai hospitals for catheter-associated urinary tract infection (CAUTI), central line-associated bloodstream infection (CLABSI), and ventilator-associated pneumonia (VAP). This ... ...

    Abstract Background: A 2014 study assessed infection prevention (IP) practices in Thai hospitals for catheter-associated urinary tract infection (CAUTI), central line-associated bloodstream infection (CLABSI), and ventilator-associated pneumonia (VAP). This study compares current IP practices to results obtained in 2014.
    Methods: Between February 1, 2021 and August 31, 2021, we resurveyed Thai hospitals regarding practices to prevent CAUTI, CLABSI, and VAP. We also assessed COVID-19 impact and healthcare worker burnout and coping strategies. We distributed 100 surveys to a convenience sample of infection preventionists.
    Results: Response rate: 100%. One-third (31%) of hospitals reported excellent leadership support for infection control (ie, responses of "good" or "excellent" to one survey question). Some prevention practices increased between 2014 vs 2021 (CAUTI: catheter reminder/stop-order/nurse-initiated discontinuation [50.0% vs 70.0%, P < .001]; condom catheters [36.3% vs 51.0%, P = .01]; ultrasound bladder scanner [4.7% vs 12.0%, P = .03]; CLABSI: chlorhexidine gluconate insertion site antisepsis [73.6% vs 85.0%, P = .03]; maximum sterile barrier precautions [63.2% vs 80.0%, P = .003]; VAP: selective digestive tract decontamination [26.9% vs 40.0%, P = .02]). Antimicrobial catheter use decreased since 2014 (10.4% vs 3.0%, P < .001). Many other practices remain suboptimal. COVID-19 challenges: staff shortages (71%), financial hardships (67%). Only 46% of infection preventionists felt safe working during COVID-19.
    Conclusions: More national strategic support is needed for IP programs to prevent CAUTI, CLABSI, VAP and healthcare worker well-being in Thailand during the COVID-19 pandemic.
    MeSH term(s) COVID-19/prevention & control ; Catheter-Related Infections/epidemiology ; Catheter-Related Infections/prevention & control ; Cross Infection/epidemiology ; Cross Infection/prevention & control ; Health Care Surveys ; Hospitals ; Humans ; Infection Control/methods ; Pandemics/prevention & control ; Pneumonia, Ventilator-Associated/prevention & control ; Thailand/epidemiology ; Urinary Tract Infections/epidemiology
    Language English
    Publishing date 2022-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2022.06.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A

    Piro, Federica / Masci, Silvia / Kannan, Geetha / Focaia, Riccardo / Schultz, Tracey L / Thaprawat, Pariyamon / Carruthers, Vern B / Di Cristina, Manlio

    mSphere

    2023  Volume 9, Issue 1, Page(s) e0059723

    Abstract: Toxoplasma ... ...

    Abstract Toxoplasma gondii
    MeSH term(s) Animals ; Humans ; Toxoplasma/metabolism ; Parasites ; Vacuoles/metabolism ; Amino Acid Transport Systems/metabolism ; Arginine/metabolism
    Chemical Substances Amino Acid Transport Systems ; Arginine (94ZLA3W45F)
    Language English
    Publishing date 2023-12-05
    Publishing country United States
    Document type Journal Article
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/msphere.00597-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Translation initiation factor eIF1.2 promotes

    Wang, Fengrong / Holmes, Michael J / Hong, Hea Jin / Thaprawat, Pariyamon / Kannan, Geetha / Huynh, My-Hang / Schultz, Tracey L / Licon, M Haley / Lourido, Sebastian / Sullivan, William J / O'Leary, Seán E / Carruthers, Vern B

    bioRxiv : the preprint server for biology

    2023  

    Abstract: ... The ... ...

    Abstract The parasite
    Language English
    Publishing date 2023-11-03
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.11.03.565545
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: HilE Regulates HilD by Blocking DNA Binding in Salmonella enterica Serovar Typhimurium.

    Grenz, Jesse R / Cott Chubiz, Jessica E / Thaprawat, Pariyamon / Slauch, James M

    Journal of bacteriology

    2018  Volume 200, Issue 8

    Abstract: ... ...

    Abstract The
    MeSH term(s) Animals ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; DNA, Bacterial/metabolism ; Gene Deletion ; Gene Expression Regulation, Bacterial ; Genomic Islands ; Mice ; Mice, Inbred BALB C ; Mutation ; Phenotype ; Promoter Regions, Genetic ; Protein Stability ; Salmonella Infections/microbiology ; Salmonella typhimurium/genetics ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcription, Genetic ; Type III Secretion Systems/genetics
    Chemical Substances Bacterial Proteins ; DNA, Bacterial ; HilC protein, Salmonella typhimurium ; HilD protein, Salmonella typhimurium ; Transcription Factors ; Type III Secretion Systems
    Language English
    Publishing date 2018-03-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/JB.00750-17
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Protection from Lethal Clostridioides difficile Infection via Intraspecies Competition for Cogerminant.

    Leslie, Jhansi L / Jenior, Matthew L / Vendrov, Kimberly C / Standke, Alexandra K / Barron, Madeline R / O'Brien, Tricia J / Unverdorben, Lavinia / Thaprawat, Pariyamon / Bergin, Ingrid L / Schloss, Patrick D / Young, Vincent B

    mBio

    2021  Volume 12, Issue 2

    Abstract: Clostridioides ... ...

    Abstract Clostridioides difficile
    MeSH term(s) Animals ; Antibiosis ; Biological Therapy ; Clostridioides difficile/classification ; Clostridioides difficile/growth & development ; Clostridioides difficile/pathogenicity ; Clostridioides difficile/physiology ; Clostridium Infections/microbiology ; Clostridium Infections/prevention & control ; Female ; Glycine/metabolism ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Microbiota ; Spores, Bacterial/classification ; Spores, Bacterial/genetics ; Spores, Bacterial/growth & development ; Spores, Bacterial/physiology ; Virulence
    Chemical Substances Glycine (TE7660XO1C)
    Language English
    Publishing date 2021-03-30
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2557172-2
    ISSN 2150-7511 ; 2161-2129
    ISSN (online) 2150-7511
    ISSN 2161-2129
    DOI 10.1128/mBio.00522-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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