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  1. Article ; Online: Evaluating the impact of genomic epidemiology of methicillin-resistant

    Blane, Beth / Raven, Kathy E / Brown, Nicholas M / Harrison, Ewan M / Coll, Francesc / Thaxter, Rachel / Enoch, David A / Gouliouris, Theodore / Leek, Danielle / Girgis, Sophia T / Akram, Asha / Matuszewska, Marta / Rhodes, Paul / Parkhill, Julian / Peacock, Sharon J

    Microbial genomics

    2024  Volume 10, Issue 4

    Abstract: Genomic epidemiology enhances the ability to detect and refute methicillin- ... ...

    Abstract Genomic epidemiology enhances the ability to detect and refute methicillin-resistant
    MeSH term(s) Humans ; Methicillin-Resistant Staphylococcus aureus/genetics ; Cross Infection/microbiology ; Staphylococcal Infections/microbiology ; Prospective Studies ; Genomics
    Language English
    Publishing date 2024-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835258-0
    ISSN 2057-5858 ; 2057-5858
    ISSN (online) 2057-5858
    ISSN 2057-5858
    DOI 10.1099/mgen.0.001235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Large-Scale Evaluation of a Rapid Fully Automated Analysis Platform to Detect and Refute Outbreaks Based on MRSA Genome Comparisons.

    Raven, Kathy E / Bragin, Eugene / Blane, Beth / Leek, Danielle / Kumar, Narender / Rhodes, Paul A / Enoch, David A / Thaxter, Rachel / Brown, Nicholas M / Parkhill, Julian / Peacock, Sharon J

    mSphere

    2022  , Page(s) e0028322

    Abstract: Genomic epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) could transform outbreak investigations, but its clinical introduction is hampered by the lack of automated data analysis tools to rapidly and accurately define transmission based ...

    Abstract Genomic epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) could transform outbreak investigations, but its clinical introduction is hampered by the lack of automated data analysis tools to rapidly and accurately define transmission based on sequence relatedness. We aimed to evaluate a fully automated bioinformatics system for MRSA genome analysis versus a bespoke researcher-led manual informatics pipeline. We analyzed 781 MRSA genomes from 777 consecutive patients identified over a 9-month period in a clinical microbiology laboratory in the United Kingdom. Outputs were bacterial species identification, detection of
    Language English
    Publishing date 2022-10-26
    Publishing country United States
    Document type Journal Article
    ISSN 2379-5042
    ISSN (online) 2379-5042
    DOI 10.1128/msphere.00283-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pilot Evaluation of a Fully Automated Bioinformatics System for Analysis of Methicillin-Resistant Staphylococcus aureus Genomes and Detection of Outbreaks.

    Brown, Nicholas M / Blane, Beth / Raven, Kathy E / Kumar, Narender / Leek, Danielle / Bragin, Eugene / Rhodes, Paul A / Enoch, David A / Thaxter, Rachel / Parkhill, Julian / Peacock, Sharon J

    Journal of clinical microbiology

    2019  Volume 57, Issue 11

    Abstract: Genomic surveillance that combines bacterial sequencing and epidemiological information will become the gold standard for outbreak detection, but its clinical translation is hampered by the lack of automated interpretation tools. We performed a ... ...

    Abstract Genomic surveillance that combines bacterial sequencing and epidemiological information will become the gold standard for outbreak detection, but its clinical translation is hampered by the lack of automated interpretation tools. We performed a prospective pilot study to evaluate the analysis of methicillin-resistant
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Automation, Laboratory ; Bacterial Typing Techniques ; Computational Biology ; Disease Outbreaks ; England ; Genome, Bacterial ; Humans ; Methicillin/pharmacology ; Methicillin-Resistant Staphylococcus aureus/classification ; Methicillin-Resistant Staphylococcus aureus/drug effects ; Multilocus Sequence Typing ; Pilot Projects ; Prospective Studies ; Sequence Analysis, DNA ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/microbiology ; Whole Genome Sequencing
    Chemical Substances Anti-Bacterial Agents ; Methicillin (Q91FH1328A)
    Language English
    Publishing date 2019-10-23
    Publishing country United States
    Document type Evaluation Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/JCM.00858-19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  4. Article: Unrecognised Outbreak: Human parainfluenza virus infections in a pediatric oncology unit.  A new diagnostic PCR and virus monitoring system may allow early detection of future outbreaks.

    Smielewska, Anna / Pearson, Callum / Popay, Ashley / Roddick, Iain / Reacher, Mark / Emmott, Edward / He, Jenny / Thaxter, Rachel / Chenery, Carol / Goodfellow, Ian / Burke, Amos / Jalal, Hamid

    Wellcome open research

    2018  Volume 3, Page(s) 119

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2018-09-19
    Publishing country England
    Document type Journal Article
    ISSN 2398-502X
    ISSN 2398-502X
    DOI 10.12688/wellcomeopenres.14732.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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