LIVIVO - Search results -

Search results

Result 1 - 10 of total 368

Search options

Article ; Online: Determining Minnesota bee species' distributions and phenologies with the help of participatory science.

Satyshur, Colleen D / Evans, Elaine C / Forsberg, Britt M / Evans, Thea A / Blair, Robert

2023 Volume 11, Page(s) e16146

Abstract: The Minnesota Bee Atlas project contributed new information about bee distributions, phenologies, and community structure by mobilizing participatory science volunteers to document bees statewide. Volunteers submitted iNaturalist (©2016 California ... ...

Abstract	The Minnesota Bee Atlas project contributed new information about bee distributions, phenologies, and community structure by mobilizing participatory science volunteers to document bees statewide. Volunteers submitted iNaturalist (©2016 California Academy of Sciences) photograph observations, monitored nest-traps for tunnel-nesting bees, and conducted roadside observational bumble bee surveys. By pairing research scientists and participatory science volunteers, we overcame geographic and temporal challenges to document the presence, phenologies, and abundances of species. Minnesota Bee Atlas project observations included new state records for
MeSH term(s)	Humans ; Bees ; Animals ; Minnesota ; Ecosystem ; Forests ; Endangered Species
Language	English
Publishing date	2023-11-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2703241-3
ISSN	2167-8359 ; 2167-8359
ISSN (online)	2167-8359
ISSN	2167-8359
DOI	10.7717/peerj.16146
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: In Silico Analysis of Anti-Inflammatory and Antioxidant Properties of Bioactive Compounds from

Gonzales, Alecsanndra L / Huang, Steven Kuan-Hua / Sevilla, Ureah Thea A / Hsieh, Cheng-Yang / Tsai, Po-Wei

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 8

Abstract: Crescentia ... ...

Abstract	Crescentia cujete
MeSH term(s)	Humans ; Antioxidants/pharmacology ; Molecular Docking Simulation ; Oxidation-Reduction ; Anti-Inflammatory Agents/pharmacology ; Inflammation/drug therapy ; Plant Extracts/pharmacology
Chemical Substances	Antioxidants ; Anti-Inflammatory Agents ; Plant Extracts
Language	English
Publishing date	2023-04-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28083547
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.MO 81: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Sperm-inherited H3K27me3 epialleles are transmitted transgenerationally in

Kaneshiro, Kiyomi Raye / Egelhofer, Thea A / Rechtsteiner, Andreas / Cockrum, Chad / Strome, Susan

Proceedings of the National Academy of Sciences of the United States of America

2022 Volume 119, Issue 40, Page(s) e2209471119

Abstract: The transmission of chromatin states from parent cells to daughter cells preserves cell-specific transcriptional states and thus cell identity through cell division. The mechanism that underpins this process is not fully understood. The role that ... ...

Abstract	The transmission of chromatin states from parent cells to daughter cells preserves cell-specific transcriptional states and thus cell identity through cell division. The mechanism that underpins this process is not fully understood. The role that chromatin states serve in transmitting gene expression information across generations via sperm and oocytes is even less understood. Here, we utilized a model in which
MeSH term(s)	Alleles ; Animals ; Caenorhabditis elegans/genetics ; Chromatin/metabolism ; Epigenesis, Genetic ; Histones/genetics ; Male ; Oocytes/metabolism ; Semen/metabolism ; Spermatozoa/metabolism
Chemical Substances	Chromatin ; Histones
Language	English
Publishing date	2022-09-26
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2209471119
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1148: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Social motivation predicts gaze following between 6 and 14 months.

Zeng, Guangyu / Leung, Tiffany S / Maylott, Sarah E / Saunders, Thea A / Messinger, Daniel S / Llabre, Maria M / Simpson, Elizabeth A

Infancy : the official journal of the International Society on Infant Studies

2023 Volume 28, Issue 4, Page(s) 836–860

Abstract: Infants vary in their ability to follow others' gazes, but it is unclear how these individual differences emerge. We tested whether social motivation levels in early infancy predict later gaze following skills. We longitudinally tracked infants' (N = 82) ...

Abstract	Infants vary in their ability to follow others' gazes, but it is unclear how these individual differences emerge. We tested whether social motivation levels in early infancy predict later gaze following skills. We longitudinally tracked infants' (N = 82) gazes and pupil dilation while they observed videos of a woman looking into the camera simulating eye contact (i.e., mutual gaze) and then gazing toward one of two objects, at 2, 4, 6, 8, and 14 months of age. To improve measurement validity, we used confirmatory factor analysis to combine multiple observed measures to index the underlying constructs of social motivation and gaze following. Infants' social motivation-indexed by their speed of social orienting, duration of mutual gaze, and degree of pupil dilation during mutual gaze-was developmentally stable and positively predicted the development of gaze following-indexed by their proportion of time looking to the target object, first object look difference scores, and first face-to-object saccade difference scores-from 6 to 14 months of age. These findings suggest that infants' social motivation likely plays a role in the development of gaze following and highlight the use of a multi-measure approach to improve measurement sensitivity and validity in infancy research.
MeSH term(s)	Female ; Humans ; Infant ; Motivation ; Fixation, Ocular
Language	English
Publishing date	2023-05-17
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2020049-3
ISSN	1532-7078 ; 1525-0008
ISSN (online)	1532-7078
ISSN	1525-0008
DOI	10.1111/infa.12544
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Fluorescent Nanodiamonds for Tracking Single Polymer Particles in Cells and Tissues

Li, Runrun / Vedelaar, Thea A. / Sigaeva, Alina / Zhang, Yue / Wu, Kaiqi / Wang, Hui / Wu, Xixi / Olinga, Peter / Wlodarzyk-Biegun, Małgorzata K. / Schirhagl, Romana

Analytical Chemistry. 2023 Aug. 23, v. 95, no. 35 p.13046-13054

2023

Abstract: Polymer nanoparticles are widely used in drug delivery and are also a potential concern due to the increased burden of nano- or microplastics in the environment. In order to use polymer nanoparticles safely and understand their mechanism of action, it is ...

Abstract	Polymer nanoparticles are widely used in drug delivery and are also a potential concern due to the increased burden of nano- or microplastics in the environment. In order to use polymer nanoparticles safely and understand their mechanism of action, it is useful to know where within cells and tissues they end up. To this end, we labeled polymer nanoparticles with nanodiamond particles. More specifically, we have embedded nanodiamond particles in the polymer particles and characterized the composites. Compared to conventional fluorescent dyes, these labels have the advantage that nanodiamonds do not bleach or blink, thus allowing long-term imaging and tracking of polymer particles. We have demonstrated this principle both in cells and entire liver tissues.
Keywords	analytical chemistry ; drugs ; fluorescence ; liver ; mechanism of action ; microplastics ; nanodiamonds ; nanoparticles
Language	English
Dates of publication	2023-0823
Size	p. 13046-13054.
Publishing place	American Chemical Society
Document type	Article ; Online
ZDB-ID	1508-8
ISSN	1520-6882 ; 0003-2700
ISSN (online)	1520-6882
ISSN	0003-2700
DOI	10.1021/acs.analchem.3c01452
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 4' 52/94: Show issues
Z 2.9: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Book ; Online: Barriers to mainstream adoption of catchment wide Natural Flood Management, a transdisciplinary problem framing study of delivery practice

Wingfield, Thea A. J. / Macdonald, Neil / Peters, Kimberley / Spees, Jack

eISSN: 1607-7938

2021

Abstract: Natural Flood Management (NFM) is the name given to Nature Based Solutions (NBS) for Flood Management in the UK. It is a holistic flood management technique that employs natural hydrological processes, through the instillation of interventions, to slow ... ...

Abstract	Natural Flood Management (NFM) is the name given to Nature Based Solutions (NBS) for Flood Management in the UK. It is a holistic flood management technique that employs natural hydrological processes, through the instillation of interventions, to slow the flow of water, creating a landscape scale flood management system. Despite widespread interest and supporting policy from governments and non-profit organisations NFM, as yet, has not been widely adopted as a mainstream flood management technique. A small number of academic studies examining perceived barriers to NFM adoption have identified a variety of individual factors as being responsible. It is commonly accepted that flood risk management broadly, and NFM specifically, are complex, challenges of interacting physical and human parameters and that academic, institutional and policy divisions are rarely sympathetic to embracing these complexities. A transdisciplinary problem framing study in conjunction with professionals experienced in the delivery of NFM projects in the UK aimed to capture these multifaceted parameters of flood management and strategic delivery at a landscape scale using Group Concept Mapping, a systems approach to identify conceptual convergence. This policy-delivery impasse was further explored by quantifying the relative importance of individual barriers and conceptual groupings from the perspective of two different practitioner groups (flood risk managers and conservation practitioners). The results demonstrate that the NFM delivery system can be grouped into seven interacting elements: policy and regulation, politics, public perception, cross-cutting issues, funding, technical knowledge and evidence , of which each have a varying number of barriers that limit NFM uptake. Opinions differs as to the importance of these individual barriers, however when considering the system broadly we identify that the institutional and social barriers are perceived as the most important, whilst technical knowledge and evidence are the areas of least concern. This paper aims to promote NBS flood management delivery in the UK and globally by generating, structuring and representing the multifaceted and multilevel NFM delivery system at a local level to evidence adaptive decision making at a regional, national and global level. Through problem structuring and an increased understanding and awareness of the structure and network of linking elements and perceived differences of practitioner groups that influence the system of delivery, steps can be taken towards solutions that are socially, scientifically and practically robust.
Subject code	910
Language	English
Publishing date	2021-07-30
Publishing country	de
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Glomerular proteomic profiling reveals early differences between preexisting and de novo type 2 diabetes in human renal allografts.

Kipp, Anne / Marti, Hans-Peter / Babickova, Janka / Nakken, Sigrid / Leh, Sabine / Halden, Thea A S / Jenssen, Trond / Vikse, Bjørn Egil / Åsberg, Anders / Spagnoli, Giulio / Furriol, Jessica

BMC nephrology

2023 Volume 24, Issue 1, Page(s) 254

Abstract: Background: Diabetes mellitus (DM), either preexisting or developing after transplantation, remains a crucial clinical problem in kidney transplantation. To obtain insights into the molecular mechanisms underlying PTDM development and early glomerular ... ...

Abstract	Background: Diabetes mellitus (DM), either preexisting or developing after transplantation, remains a crucial clinical problem in kidney transplantation. To obtain insights into the molecular mechanisms underlying PTDM development and early glomerular damage before the development of histologically visible diabetic kidney disease, we comparatively analysed the proteome of histologically normal glomeruli from patients with PTDM and normoglycaemic (NG) transplant recipients. Moreover, to assess specificities inherent in PTDM, we also comparatively evaluated glomerular proteomes from transplant recipients with preexisting type 2 DM (T2DM). Methods: Protocol biopsies were obtained from adult NG, PTDM and T2DM patients one year after kidney transplantation. Biopsies were formalin-fixed and embedded in paraffin, and glomerular cross-sections were microdissected. A total of 4 NG, 7 PTDM and 6 T2DM kidney biopsies were used for the analysis. The proteome was determined by liquid chromatography-tandem mass spectrometry. Relative differences in protein abundance and significantly dysregulated pathways were analysed. Results: Proteins involved in cell adhesion, immune response, leukocyte transendothelial filtration, and cell localization and organization were less abundant in glomeruli from PTDM patients than in those from NG patients, and proteins associated with supramolecular fibre organization and protein-containing complex binding were more abundant in PTDM patients. Overall, proteins related to adherens and tight junctions and those related to the immune system, including leukocyte transendothelial migration, were more abundant in NG patients than in transplanted patients with DM, irrespective of the timing of its development. However, proteins included in cell‒cell junctions and adhesion, insulin resistance, and vesicle-mediated transport were all less abundant in PTDM patients than in T2DM patients. Conclusions: The glomerular proteome profile differentiates PTDM from NG and T2DM, suggesting specific pathogenetic mechanisms. Further studies are warranted to validate these results, potentially leading to an improved understanding of PTDM kidney transplant pathophysiology and to the identification of novel biomarkers.
MeSH term(s)	Adult ; Humans ; Kidney Transplantation ; Diabetes Mellitus, Type 2 ; Proteome ; Proteomics ; Kidney ; Diabetic Nephropathies ; Allografts
Chemical Substances	Proteome
Language	English
Publishing date	2023-08-25
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041348-8
ISSN	1471-2369 ; 1471-2369
ISSN (online)	1471-2369
ISSN	1471-2369
DOI	10.1186/s12882-023-03294-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Fluorescent Nanodiamonds for Tracking Single Polymer Particles in Cells and Tissues.

Li, Runrun / Vedelaar, Thea A / Sigaeva, Alina / Zhang, Yue / Wu, Kaiqi / Wang, Hui / Wu, Xixi / Olinga, Peter / Wlodarzyk-Biegun, Małgorzata K / Schirhagl, Romana

Analytical chemistry

2023 Volume 95, Issue 35, Page(s) 13046–13054

Abstract	Polymer nanoparticles are widely used in drug delivery and are also a potential concern due to the increased burden of nano- or microplastics in the environment. In order to use polymer nanoparticles safely and understand their mechanism of action, it is useful to know where within cells and tissues they end up. To this end, we labeled polymer nanoparticles with nanodiamond particles. More specifically, we have embedded nanodiamond particles in the polymer particles and characterized the composites. Compared to conventional fluorescent dyes, these labels have the advantage that nanodiamonds do not bleach or blink, thus allowing long-term imaging and tracking of polymer particles. We have demonstrated this principle both in cells and entire liver tissues.
MeSH term(s)	Nanodiamonds ; Plastics ; Fluorescent Dyes ; Drug Delivery Systems ; Polymers
Chemical Substances	Nanodiamonds ; Plastics ; Fluorescent Dyes ; Polymers
Language	English
Publishing date	2023-08-23
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1508-8
ISSN	1520-6882 ; 0003-2700
ISSN (online)	1520-6882
ISSN	0003-2700
DOI	10.1021/acs.analchem.3c01452
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4033: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Applying NV center-based quantum sensing to study intracellular free radical response upon viral infections

Kaiqi Wu / Thea A. Vedelaar / Viraj G. Damle / Aryan Morita / Julie Mougnaud / Claudia Reyes San Martin / Yue Zhang / Denise P.I. van der Pol / Heidi Ende-Metselaar / Izabela Rodenhuis-Zybert / Romana Schirhagl

Redox Biology, Vol 52, Iss , Pp 102279- (2022)

2022

Abstract: Although viruses are known to modify the free radical concentration in infected cells, the exact location and concentrations of such changes remain unknown. Although this information is important to understand the virus pathogenesis and design better ... ...

Abstract	Although viruses are known to modify the free radical concentration in infected cells, the exact location and concentrations of such changes remain unknown. Although this information is important to understand the virus pathogenesis and design better anti-viral drugs or vaccines, obtaining it with the conventional free radical/ROS detection techniques is impossible. Here, we elucidate the utility of diamond magnetometry for studying the free radical response of baby hamster kidney-21 cells upon Semliki Forest virus infection. Specifically, we optically probe the alterations in free radical concentration near infectious viruses via measuring the spin–lattice relaxation (T1) of NV defect ensembles embedded in intracellular nanodiamonds. We performed measurements both at random locations as well as close to the virus entry by conjugating viruses to nanodiamond sensors. We observed alterations of T1, which represent the intracellular free radical concentration during the viral replication process. Moreover, relaxometry is also used to monitor real-time free radical variation during the early infectious process.
Keywords	Fluorescent nanodiamonds ; Free radicals ; Viral infections ; Diamond magnetometry ; NV centers ; ROS ; Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
Subject code	500
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Repression of Germline Genes in

Rechtsteiner, Andreas / Costello, Meghan E / Egelhofer, Thea A / Garrigues, Jacob M / Strome, Susan / Petrella, Lisa N

Genetics

2019 Volume 212, Issue 1, Page(s) 125–140

Abstract: Repression of germline-promoting genes in somatic cells is critical for somatic development and function. To study how germline genes are repressed in somatic tissues, we analyzed key histone modifications in ... ...

Abstract	Repression of germline-promoting genes in somatic cells is critical for somatic development and function. To study how germline genes are repressed in somatic tissues, we analyzed key histone modifications in three
MeSH term(s)	Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Caenorhabditis elegans Proteins/genetics ; Gene Expression Regulation, Developmental ; Germ Cells ; Histones/metabolism ; Methylation ; Promoter Regions, Genetic ; Protein Processing, Post-Translational
Chemical Substances	Caenorhabditis elegans Proteins ; Histones
Language	English
Publishing date	2019-03-25
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2167-2
ISSN	1943-2631 ; 0016-6731
ISSN (online)	1943-2631
ISSN	0016-6731
DOI	10.1534/genetics.118.301878
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 767: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito