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Article ; Online: Review of the spider wasp genus Episyron Schidte, 1837 (Hymenoptera: Pompilidae) from India, with description of three new species.

Anju, K / Kumar, P Girish / Thejass, P

Zootaxa

2024 Volume 5405, Issue 4, Page(s) 562–576

Abstract: The spider wasp genus Episyron Schidte, 1837 is reviewed, with five species recorded from various parts of India along with three new species described and illustrated from Kerala: E. keralaensis Anju, Girish Kumar & Thejass, sp. nov., E. nigrocalcarius ... ...

Abstract	The spider wasp genus Episyron Schidte, 1837 is reviewed, with five species recorded from various parts of India along with three new species described and illustrated from Kerala: E. keralaensis Anju, Girish Kumar & Thejass, sp. nov., E. nigrocalcarius Anju, Girish Kumar & Thejass, sp. nov., and E. rufotibius Anju, Girish Kumar & Thejass, sp. nov. Diagnosis of species occurring in India, comparisons of new species with congeners and a key to the Indian species also are provided.
MeSH term(s)	Animals ; Wasps ; Hymenoptera ; India ; Lepidoptera
Language	English
Publishing date	2024-02-01
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.5405.4.5
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Article ; Online: Taxonomic study on the spider wasp genus Ceropales Latreille, 1796 (Pompilidae: Ceropalinae) with description of two new species from India.

Anju, K / Thejass, P / Binoy, C / Kumar, P Girish

Zootaxa

2023 Volume 5264, Issue 1, Page(s) 119–128

Abstract: The spider wasp genus Ceropales Latreille, 1796 from India was studied, resulting in the discovery of two new species in the nominotypical subgenus: Ceropales (Ceropales) anaghae Anju, Girish Kumar & Thejass, sp. nov. and C. (C.) keralaensis Anju, Binoy & ...

Abstract	The spider wasp genus Ceropales Latreille, 1796 from India was studied, resulting in the discovery of two new species in the nominotypical subgenus: Ceropales (Ceropales) anaghae Anju, Girish Kumar & Thejass, sp. nov. and C. (C.) keralaensis Anju, Binoy & Thejass, sp. nov. Description of the new species with illustrations, comparisons with congeners and a key to Indian species of the subgenus are also provided.
MeSH term(s)	Animals ; Wasps ; India
Language	English
Publishing date	2023-04-12
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.5264.1.8
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Article ; Online: Chemical Composition and Biological Activities of the Essential Oil from Citrus reticulata Blanco Peels Collected from Agrowastes.

Job, Joice Tom / Visakh, Naduvilthara U / Pathrose, Berin / Alfarhan, Ahmed / Rajagopal, Rajakrishnan / Thayyullathil, Jobiraj / Thejass, P / Ramesh, Varsha / Narayanankutty, Arunaksharan

Chemistry & biodiversity

2024 Volume 21, Issue 3, Page(s) e202301223

Abstract: Citrus fruits have a thick outer coat which is often discarded due to its low economic value and usually contributes to the waste. So this work focused on exploring the potential pharmacological properties of the discarded citrus peels. In the present ... ...

Abstract	Citrus fruits have a thick outer coat which is often discarded due to its low economic value and usually contributes to the waste. So this work focused on exploring the potential pharmacological properties of the discarded citrus peels. In the present study, we extracted the essential oil from peel wastes of Citrus reticulata Blanco (CREO) from the local market. The antioxidant, antibacterial, and anticancer properties of essential oil were evaluated. The CREO exhibited a strong antioxidant property with DPPH radical scavenging, ABTS radical scavenging, H
MeSH term(s)	Oils, Volatile/pharmacology ; Oils, Volatile/chemistry ; Antioxidants/pharmacology ; Antioxidants/chemistry ; Escherichia coli ; Staphylococcus aureus ; Citrus/chemistry ; Anti-Bacterial Agents/pharmacology
Chemical Substances	Oils, Volatile ; Antioxidants ; Anti-Bacterial Agents
Language	English
Publishing date	2024-02-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2139001-0
ISSN	1612-1880 ; 1612-1872
ISSN (online)	1612-1880
ISSN	1612-1872
DOI	10.1002/cbdv.202301223
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Article ; Online: Description of a new species of spider wasp Genus Machaerothrix Haupt<br />(Hymenoptera: Pompilidae) from India with reports on its host ssociation and nesting behaviour.

Binoy, C / Anju, K / Thejass, P

Zootaxa

2020 Volume 4766, Issue 1, Page(s) zootaxa.4766.1.11

Abstract: The little-known spider wasp genus Machaerothrix Haupt, 1938 is recorded for the first time from India with the description and illustrations of both sexes of a seventh species from the World. The biology, habitat, prey preference and transport, nest ... ...

Abstract	The little-known spider wasp genus Machaerothrix Haupt, 1938 is recorded for the first time from India with the description and illustrations of both sexes of a seventh species from the World. The biology, habitat, prey preference and transport, nest structure and nesting behaviour of the new species is studied and the association of the wasps with salticid spiders (Araneae: Salticidae) is here validated.
MeSH term(s)	Animals ; Ecosystem ; Female ; India ; Male ; Nesting Behavior ; Spiders ; Wasps
Language	English
Publishing date	2020-04-17
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.4766.1.11
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Article ; Online: The threat of microplastics: Exploring pollution in coastal ecosystems and migratory shorebirds along the west coast of India.

Athira, T R / Aarif, K M / Thomas, Jeniffer Ann / Alatawi, Abdulaziz S / Muzaffar, Sabir Bin / Nefla, Aymen / Reshi, Omer R / Jobiraj, T / Thejass, P

Marine pollution bulletin

2023 Volume 198, Page(s) 115912

Abstract: To evaluate the exposure risk and ingestion of microplastics by migratory shorebirds, which are regarded as apex predators in the coastal ecosystem, this study investigated the ubiquitous presence of microplastics in estuarine and coastal habitats and ... ...

Abstract	To evaluate the exposure risk and ingestion of microplastics by migratory shorebirds, which are regarded as apex predators in the coastal ecosystem, this study investigated the ubiquitous presence of microplastics in estuarine and coastal habitats and their potential to be transferred in the food chains. We analysed the presence of microplastics in water, sediment, major macroinvertebrate prey and the guano samples of ten shorebird species from ten important wintering grounds in the west coast of India. Our results revealed that water is the primary source through which microplastics disseminate into various ecosystem components. Microplastic debris in various forms were reported in all samples analysed, with microfibres being the most abundant form. While polyethylene and polypropylene were found as the major microplastic types in water, sediment, and prey samples, polystyrene was most abundant in guano samples. Microplastic transfer and impacts in this delicate ecosystem demand further investigations.
MeSH term(s)	Microplastics ; Ecosystem ; Plastics/analysis ; Environmental Monitoring/methods ; Water Pollutants, Chemical/analysis ; Water/analysis ; India
Chemical Substances	Microplastics ; Plastics ; Water Pollutants, Chemical ; Water (059QF0KO0R)
Language	English
Publishing date	2023-12-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2001296-2
ISSN	1879-3363 ; 0025-326X
ISSN (online)	1879-3363
ISSN	0025-326X
DOI	10.1016/j.marpolbul.2023.115912
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Article ; Online: The impact of long-term environmental change on zooplankton along the southwestern coast of India.

Athira, T R / Nefla, Aymen / Shifa, C T / Shamna, H / Aarif, K M / AlMaarofi, Sama S / Rashiba, A P / Reshi, Omer R / Jobiraj, T / Thejass, P / Muzaffar, Sabir Bin

Environmental monitoring and assessment

2022 Volume 194, Issue 4, Page(s) 316

Abstract: Environmental pollution and climate change are causing major changes in the marine environment. Coastal zones around the world are experiencing changes such as nutrient influx, resulting in altered plankton communities. The aim of this study was to ... ...

Abstract	Environmental pollution and climate change are causing major changes in the marine environment. Coastal zones around the world are experiencing changes such as nutrient influx, resulting in altered plankton communities. The aim of this study was to determine the response of zooplankton to the changes in the environmental variables in the coastal zone of the Arabian Sea, Southwest Coast of India, over 10 years. Zooplankton abundance, chlorophyll-a concentrations, and water quality variables (rainfall, nitrates, phosphates, pH, water temperature, and salinity) were quantified from January 2010 to December 2019. Water temperature, pH, salinity, and phosphates increased steadily across the sites during the study period whereas chlorophyll-a and nitrates decreased. Rainfall abundance was not exhibiting any patterns or trends. The effects of the sampled environmental variables on zooplankton abundance were tested using generalized linear mixed models. Salinity and phosphates negatively affected the zooplankton abundance whereas water temperature, pH, and chlorophyll-a concentration had a positive effect. Coastal zones in southwest India are experiencing declining phytoplankton abundance due to a number of environmental factors. Reduced phytoplankton combined with altered environmental variables are having declining effects on zooplankton. This decline in zooplankton population has far reaching effects on biota in higher trophic levels including economically important organisms such as fishes.
MeSH term(s)	Animals ; Chlorophyll A ; Environmental Monitoring ; Phytoplankton ; Plankton ; Zooplankton
Chemical Substances	Chlorophyll A (YF5Q9EJC8Y)
Language	English
Publishing date	2022-03-31
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	782621-7
ISSN	1573-2959 ; 0167-6369
ISSN (online)	1573-2959
ISSN	0167-6369
DOI	10.1007/s10661-022-09921-w
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Article: Modulation of cell-mediated immune response in B16F-10 melanoma-induced metastatic tumor-bearing C57BL/6 mice by sulforaphane.

Thejass, P / Kuttan, G

Immunopharmacology and immunotoxicology

2007 Volume 29, Issue 2, Page(s) 173–186

Abstract: Effect of sulforaphane on cell-mediated immune response (CMI) was studied in B16F-10 melanoma-induced metastasis-bearing C57BL/6 mice. Administration of sulforaphane significantly enhanced natural killer (NK) cell activity in metastatic tumor-bearing ... ...

Abstract	Effect of sulforaphane on cell-mediated immune response (CMI) was studied in B16F-10 melanoma-induced metastasis-bearing C57BL/6 mice. Administration of sulforaphane significantly enhanced natural killer (NK) cell activity in metastatic tumor-bearing animals (43.17% cell lysis, on day 5) and the activity was observed earlier than in tumor-bearing control animals (maximum of 9.76% cell lysis, on day 9). Antibody-dependent cellular cytotoxicity also was enhanced significantly in metastatic tumor-bearing animals (41.20% cell lysis on day 9) after sulforaphane administration compared with untreated control tumor-bearing animals (maximum of 12.62% cell lysis on day 15). An early antibody-dependent complement-mediated cytotoxicity also was observed in sulforaphane-treated tumor-bearing animals (26% cell lysis, on day 15). Administration of sulforaphane significantly enhanced the production of IL-2 and IFN-gamma in metastatic tumor-bearing animals. In addition, sulforaphane significantly downregulated the serum levels of proinflammatory cytokines such as IL-1beta, IL-6, TNF-alpha, and GM-CSF during metastasis. These data clearly suggest that sulforaphane effectively inhibited the spread of metastatic tumor cells through the stimulation of CMI, upregulation of IL-2 and IFN-gamma, and downregulation of proinflammatory cytokines IL-1beta, IL-6, TNF-alpha, and GM-CSF.
MeSH term(s)	Animals ; Antibody-Dependent Cell Cytotoxicity/drug effects ; Anticarcinogenic Agents/pharmacology ; Complement System Proteins/physiology ; Cytokines/metabolism ; Granulocyte Colony-Stimulating Factor/pharmacology ; Humans ; Immunity, Cellular/drug effects ; Interferon-gamma/pharmacology ; Interleukin-2/pharmacology ; Isothiocyanates ; K562 Cells ; Killer Cells, Natural/drug effects ; Killer Cells, Natural/immunology ; Male ; Melanoma, Experimental/immunology ; Mice ; Mice, Inbred C57BL ; Neoplasm Metastasis/immunology ; Recombinant Proteins ; Thiocyanates/pharmacology
Chemical Substances	Anticarcinogenic Agents ; Cytokines ; Interleukin-2 ; Isothiocyanates ; Recombinant Proteins ; Thiocyanates ; Granulocyte Colony-Stimulating Factor (143011-72-7) ; Interferon-gamma (82115-62-6) ; Complement System Proteins (9007-36-7) ; sulforaphane (GA49J4310U)
Language	English
Publishing date	2007-09-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	807033-7
ISSN	1532-2513 ; 0892-3973
ISSN (online)	1532-2513
ISSN	0892-3973
DOI	10.1080/08923970701511728
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Article: Antiangiogenic activity of Diallyl Sulfide (DAS).

Thejass, P / Kuttan, Girija

International immunopharmacology

2007 Volume 7, Issue 3, Page(s) 295–305

Abstract: Antiangiogenic activity of Diallyl sulfide (DAS) was studied using in vivo as well as in vitro models. In vivo antiangiogenic activity was studied using B16F-10 melanoma cell induced capillary formation in C57BL/6 mice. DAS significantly inhibited tumour ...

Abstract	Antiangiogenic activity of Diallyl sulfide (DAS) was studied using in vivo as well as in vitro models. In vivo antiangiogenic activity was studied using B16F-10 melanoma cell induced capillary formation in C57BL/6 mice. DAS significantly inhibited tumour directed capillary formation. Studies of serum cytokine profile of angiogenesis induced animals clearly showed that DAS significantly reduced the production of proinflammatory cytokines such as IL-1beta, IL-6, TNF-alpha and GM-CSF which are known proangiogenic factors. The serum level of VEGF, an important proangiogenic factor, in angiogenesis induced animals was found to be significantly reduced upon treatment with DAS which may be due to its efficacy in the down regulation of VEGF mRNA expression. Administration of DAS significantly enhanced the production of antiangiogenic factors such as IL-2 and TIMP. In vitro studies using rat aortic ring assay showed that administration of DAS at no n-toxic concentrations significantly inhibited microvessel sprouting. Studies using Human umbilical vein endothelial cells (HUVECs) clearly demonstrated that administration of DAS significantly retarded endothelial cell proliferation, migration, invasion and tube formation. These data clearly suggests that antiangiogenic activity of DAS can be related to its negative regulation of proangiogenic factors such as VEGF and proinflammatory cytokines and positive regulation of antiangiogenic factors such as IL-2 and TIMP.
MeSH term(s)	Allyl Compounds/pharmacology ; Angiogenesis Inhibitors/pharmacology ; Animals ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Endothelial Cells/cytology ; Endothelial Cells/drug effects ; Granulocyte-Macrophage Colony-Stimulating Factor/biosynthesis ; Humans ; Interleukin-2/blood ; Interleukin-6/biosynthesis ; Male ; Mice ; Mice, Inbred C57BL ; Neovascularization, Physiologic/drug effects ; RNA, Messenger/analysis ; Sulfides/pharmacology ; Tissue Inhibitor of Metalloproteinase-1/blood ; Tumor Necrosis Factor-alpha/biosynthesis ; Vascular Endothelial Growth Factor A/biosynthesis
Chemical Substances	Allyl Compounds ; Angiogenesis Inhibitors ; Interleukin-2 ; Interleukin-6 ; RNA, Messenger ; Sulfides ; Tissue Inhibitor of Metalloproteinase-1 ; Tumor Necrosis Factor-alpha ; Vascular Endothelial Growth Factor A ; allyl sulfide (60G7CF7CWZ) ; Granulocyte-Macrophage Colony-Stimulating Factor (83869-56-1)
Language	English
Publishing date	2007-03
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2043785-7
ISSN	1567-5769
ISSN	1567-5769
DOI	10.1016/j.intimp.2006.10.011
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Article: Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by diallyl disulfide (DADS).

Thejass, P / Kuttan, Girija

Life sciences

2007 Volume 80, Issue 6, Page(s) 515–521

Abstract: Angiogenesis is a crucial step in the growth and metastasis of cancers. The activation of endothelial cells and their further behaviour are very critical during angiogenesis. We analyzed the effect of diallyl disulfide (DADS) on angiogenesis in in vitro ... ...

Abstract	Angiogenesis is a crucial step in the growth and metastasis of cancers. The activation of endothelial cells and their further behaviour are very critical during angiogenesis. We analyzed the effect of diallyl disulfide (DADS) on angiogenesis in in vitro models using human umbilical vein endothelial cells (HUVECs). DADS significantly inhibited endothelial cell migration, invasion and tube formation. (3)H-thymidine proliferation assay clearly showed the inhibitory effect of DADS on the proliferation of HUVECs in vitro. The role of metalloproteinases has been shown to be important in angiogenesis; therefore, zymography was performed to determine whether DADS affected protease activity. Gelatin zymographic analysis showed the inhibitory effect of DADS on the activation of matrix metalloproteinases-MMP-2 and MMP-9. These findings suggest that DADS acts as an angiogenesis inhibitor by inhibiting the activation of matrix metalloproteinases during endothelial morphogenesis.
MeSH term(s)	Allyl Compounds/pharmacology ; Angiogenesis Inhibitors/pharmacology ; Cell Differentiation/drug effects ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Disulfides/pharmacology ; Dose-Response Relationship, Drug ; Endothelial Cells/drug effects ; Endothelial Cells/pathology ; Humans ; Models, Biological ; Neovascularization, Pathologic/prevention & control ; Umbilical Veins/cytology
Chemical Substances	Allyl Compounds ; Angiogenesis Inhibitors ; Disulfides ; diallyl disulfide (5HI47O6OA7)
Language	English
Publishing date	2007-01-16
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3378-9
ISSN	1879-0631 ; 0024-3205
ISSN (online)	1879-0631
ISSN	0024-3205
DOI	10.1016/j.lfs.2006.09.045
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Article: Inhibition of endothelial cell differentiation and proinflammatory cytokine production during angiogenesis by allyl isothiocyanate and phenyl isothiocyanate.

Thejass, P / Kuttan, Girija

Integrative cancer therapies

2007 Volume 6, Issue 4, Page(s) 389–399

Abstract: Angiogenesis is a crucial step in the growth and metastasis of cancers. The activation of endothelial cells and their further behavior are very critical during angiogenesis. The authors analyze the effect of allyl isothiocyanate (AITC) and phenyl ... ...

Abstract	Angiogenesis is a crucial step in the growth and metastasis of cancers. The activation of endothelial cells and their further behavior are very critical during angiogenesis. The authors analyze the effect of allyl isothiocyanate (AITC) and phenyl isothiocyanate (PITC) on angiogenesis in an in vitro model using human umbilical vein endothelial cells (HUVECs). AITC and PITC significantly inhibited endothelial cell migration, invasion, and tube formation. (3)H-thymidine proliferation assay showed that AITC and PITC significantly inhibited the proliferation of HUVECs in vitro. The authors also studied the effect of AITC and PITC on the serum cytokine profiles of angiogenesis-induced animals and found that these compounds are highly potent in the downregulation of vascular endothelial growth factor (VEGF) and proinflammatory cytokines such as interleukin (IL)-1beta , IL-6, granulocyte macrophage colony-stimulating factor (GM-CSF), and tumor necrosis factor alpha (TNF-alpha). Treatment with these compounds showed an elevation in the levels of IL-2 and tissue inhibitor of metalloproteinases (TIMP)-1, which are antiangiogenic factors. Moreover, studies using B16F-10 melanoma cells showed that both AITC and PITC significantly reduced VEGF mRNA expression. These findings suggest that AITC and PITC act as angiogenesis inhibitors through the downregulation of VEGF and proinflammatory cytokines such as IL-1beta, IL-6, GM-CSF, and TNF-alpha and upregulation of IL-2 and TIMP.
MeSH term(s)	Angiogenesis Inhibitors/pharmacology ; Animals ; Cell Differentiation/drug effects ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Cytokines/blood ; Endothelial Cells/cytology ; Endothelial Cells/drug effects ; Endothelial Cells/metabolism ; Fibroblast Growth Factors/pharmacology ; Gene Expression/drug effects ; Granulocyte-Macrophage Colony-Stimulating Factor/blood ; Humans ; Interleukins/blood ; Isothiocyanates/pharmacology ; Male ; Melanoma, Experimental/blood supply ; Melanoma, Experimental/pathology ; Melanoma, Experimental/prevention & control ; Mice ; Mice, Inbred C57BL ; Neovascularization, Pathologic/blood ; Neovascularization, Pathologic/drug therapy ; Tissue Inhibitor of Metalloproteinase-1/blood ; Tumor Necrosis Factor-alpha/blood ; Vascular Endothelial Growth Factor A/blood ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/pharmacology
Chemical Substances	Angiogenesis Inhibitors ; Cytokines ; Interleukins ; Isothiocyanates ; Tissue Inhibitor of Metalloproteinase-1 ; Tumor Necrosis Factor-alpha ; Vascular Endothelial Growth Factor A ; vascular endothelial growth factor A, mouse ; phenylisothiocyanate (0D58F84LSU) ; Fibroblast Growth Factors (62031-54-3) ; Granulocyte-Macrophage Colony-Stimulating Factor (83869-56-1) ; allyl isothiocyanate (BN34FX42G3)
Language	English
Publishing date	2007-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2182320-0
ISSN	1552-695X ; 1534-7354
ISSN (online)	1552-695X
ISSN	1534-7354
DOI	10.1177/1534735407309084
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