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  1. Article ; Online: The effects of extraction conditions on the yield of crude pectin extract from passion fruit (Passiflora edulis Sims.) and the application of the extract on jam forming ability

    Trung Hau Nguyen / Hoai Xuan Nu Tran / Thi Thuy Vu / Thi Thuy Linh Ho / Thi Tuong Van Nguyen

    Can Tho University Journal of Science, Vol 14, Iss

    2022  Volume 2

    Abstract: The peel of purple passion fruit (Passiflora edulis Sims.) can account for up to 60% of the total weight and contains usable organic compounds such as polymeric sugars, including pectin. The influences of ripeness stages and the extraction conditions ( ... ...

    Abstract The peel of purple passion fruit (Passiflora edulis Sims.) can account for up to 60% of the total weight and contains usable organic compounds such as polymeric sugars, including pectin. The influences of ripeness stages and the extraction conditions (solvents, peel to solvent ratio, temperature, time) on the extract of crude pectin yield were investigated. The results indicated that pectin yield was independent of fruit maturation. The extraction efficiency reached its peak when extracted with citric acid and demonstrated optimal pectin production yield with the ratio of 1:5 (w/v) and at 95°C for 80 minutes. The extracted crude pectin was then applied to mango jam production. Jam made from extracted pectin had a good structure, moderate hardness, nice color, and harmonious taste. The ability to form coagulation on mango jam of crude pectin was weaker than commercial pectin. This study found that the topic's practical applicability to the processing of food products was significant.
    Keywords acid ; extraction ; passion fruit peel ; pectin ; yield ; Social sciences (General) ; H1-99 ; Agriculture (General) ; S1-972 ; Engineering (General). Civil engineering (General) ; TA1-2040
    Subject code 660
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher CAN THO UNIVERSITY PUBLISHING HOUSE
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Viral and bacterial microorganisms in Vietnamese children with severe and non-severe pneumonia

    Xuan Duong Tran / Van-Thuan Hoang / Ndiaw Goumballa / Thi Nguyet Vu / Trong Kiem Tran / Thi Dung Pham / Thi-Loi Dao / Thi Thuy Vu / Duy Cuong Nguyen / Quoc Tien Nguyen / Pierre Marty / Philippe Gautret

    Scientific Reports, Vol 14, Iss 1, Pp 1-

    2024  Volume 10

    Abstract: Abstract To investigate potential respiratory pathogens in children with community-acquired pneumonia (CAP) and risk factors for severe disease. This prospective study was conducted among 467 children at the Thai Binh Paediatric Hospital, Vietnam between ...

    Abstract Abstract To investigate potential respiratory pathogens in children with community-acquired pneumonia (CAP) and risk factors for severe disease. This prospective study was conducted among 467 children at the Thai Binh Paediatric Hospital, Vietnam between 1 July 2020 and 30 June 2021. Clinical data and laboratory results were collected. Twenty-four respiratory microorganisms were tested from nasopharyngeal swabs using real-time PCR. Logistical regression was used to estimate a factor’s adjusted odd ratios of the severity of disease. Mean age of patients = 15.4 ± 13.3 months, 63.0% were male. Over 97% of patients had a positive PCR result. 87% of patients were positive for multiple (up to eight) microorganisms. Rhinovirus (46%), respiratory syncytial virus (RSV) (24%), enterovirus (17%), and parainfluenza viruses-3 (13%) were the most frequent viruses. H. influenzae (61%), S. pneumoniae (45%) and M. catarrhalis (30%) were the most common bacteria. 128 (27%) cases were classified as severe pneumonia. Presence of smokers at home (aOR 2.11, 95% CI 1.27–3.52, P value = 0.004), CRP level ≥ 50 mg/dL (aOR 6.11, 95% CI 3.86–9.68, P value < 0.0001), RSV (aOR 1.78, 95% CI 1.07–2.96, P value = 0.03) and H. influenzae (aOR 1.66, 95% CI 1.03–2.67, P value = 0.04) PCR detection associated with a higher risk of severe pneumonia; ,. Causative agents of pneumonia in children are complex. Children positive with RSV and H. influenzae need to be closely monitored to prevent severe pneumonia.
    Keywords Medicine ; R ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Effects of nitrite exposure on haematological parameters and growth in clown knifefish (Chitala ornata, Gray 1831)

    Thi Hong Gam Le / Thanh Phuong Nguyen / Thi Thuy Vu Nguyen / Thi Thanh Huong Do / Ngoc Nhu Pham

    Can Tho University Journal of Science, Vol 54, Iss

    2018  Volume 2

    Abstract: Physiological responses and growth of clown knifefish (Chitala ornata) (initial weight of 11-12 g) exposed to nitrite were investigated with three separate experiments. The first experiment was to determine the nitrite concentration causing 50% mortality ...

    Abstract Physiological responses and growth of clown knifefish (Chitala ornata) (initial weight of 11-12 g) exposed to nitrite were investigated with three separate experiments. The first experiment was to determine the nitrite concentration causing 50% mortality in 96 hours (96-h LC50). The second experiment examined the effects of different nitrite concentrations on haematological parameters. The third experiment investigated into the effects of different nitrite concentrations on fish growth including 4 treatments such as control, 0.2 mM nitrite, 0.4 mM nitrite, and 4 mM nitrite for measuring growth parameters at days 0, 30, 60, and 90 days (sampling 30 fish/tank). The results showed that the clown knifefish had high nitrite tolerance with 96-h LC50 of 7.82 mM. There were significant increases in methaemoglobin and leukocytes while other haematological parameters decreased during nitrite exposures at the treatment of 4 mM nitrite. Particularly, methaemoglobin and the number of leukocytes increased from 0.4 to 29.5%, and from 39.89x103 to 72.33x103 cells/mm3, respectively. Differently, there were significant declines in the number of erythrocyte (3.19x106–2.33x106 cells/mm3), haemoglobin (10.47-7.04 mM), and haematocrit (38.07-26.5%) at the highest nitrite treatment. After 90 days, daily weight gain (0.25±0.02 g/day), specific growth rate (1.18±0.07 %/day), survival rate (59%) at the treatment of 4 mM nitrite were significantly lower than those of the control, but no significant difference was observed in such parameters between the control and the treatments of 0.2 or 0.4 mM nitrite.
    Keywords Clown knifefish ; growth ; haematological parameters ; nitrite ; Social sciences (General) ; H1-99 ; Agriculture (General) ; S1-972 ; Engineering (General). Civil engineering (General) ; TA1-2040
    Subject code 630
    Language English
    Publishing date 2018-03-01T00:00:00Z
    Publisher CAN THO UNIVERSITY PUBLISHING HOUSE
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Small-scale experiments aimed at optimization of large-scale production of the microalga Rhodomonas salina

    Thoisen, Christina / Benni Winding Hansen / Minh Thi Thuy Vu / Per Meyer Jepsen / Søren Laurentius Nielsen / Thibaut Carron-Cabaret

    Journal of applied phycology. 2018 Aug., v. 30, no. 4

    2018  

    Abstract: The cryptophyte Rhodomonas is an important feed item for live feed organisms in aquaculture and although large-scale cultivation of Rhodomonas in photobioreactors (PBRs) is feasible, the production needs to be optimized through further studies of ... ...

    Abstract The cryptophyte Rhodomonas is an important feed item for live feed organisms in aquaculture and although large-scale cultivation of Rhodomonas in photobioreactors (PBRs) is feasible, the production needs to be optimized through further studies of specific factors. Through small-scale experiments, several factors relevant for an on-going large-scale production of Rhodomonas were studied and the results presented here provide a useful insight on factors that can help future large-scale production. The content of polyunsaturated fatty acids (PUFAs) and the temporal sedimentation was compared in five strains of Rhodomonas. Strain K-1487 (R. salina) was chosen as the most suitable for cultivation in PBRs due to a good biochemical content of PUFAs and low cell sedimentation. The f/2 growth medium used for cultivation was modified by excluding CoCl2 which did not affect either growth rate or cell content of the PUFAs, DHA, EPA, and ARA. Furthermore, the growth medium was modified by adding the nitrogen source as ammonium (NH4+), nitrate (NO3−), urea, or combinations of these, with NH4+ yielding a significantly higher growth rate of 1.30 ± 0.07 day−1. The seawater used for cultivation was exposed to three types of treatments which gave no significant difference in the growth rate: (1) filtration (0.2 μm) + autoclaving, (2) filtration (0.2 μm) + UV-radiation, and (3) filtration (0.2 μm). Finally, the results for growth rates of inocula at initial densities ranging from 2000 to 200,000 cells mL−1 showed that growth rate decreased with increasing density but a final density of 106 cells mL−1 was obtained fastest with the highest initial density. With the present findings, several barriers for effective cultivation of Rhodomonas are solved and future large-scale production has become a great step closer.
    Keywords algae culture ; ammonium ; autoclaving ; cell proliferation ; culture media ; filtration ; microalgae ; nitrates ; nitrogen ; photobioreactors ; polyunsaturated fatty acids ; Rhodomonas ; seawater ; ultraviolet radiation ; urea
    Language English
    Dates of publication 2018-08
    Size p. 2193-2202.
    Publishing place Springer Netherlands
    Document type Article
    ZDB-ID 1002324-0
    ISSN 1573-5176 ; 0921-8971
    ISSN (online) 1573-5176
    ISSN 0921-8971
    DOI 10.1007/s10811-018-1434-1
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Morbidity and Mortality Patterns in Children Admitted to Hospital in Thai Binh, Vietnam

    Thi Dung Pham / Van Thuan Hoang / Thi Loi Dao / Xuan Duong Tran / Duc Long Phi / Minh Manh To / Van Nghiem Dang / Van Khoi Dang / Thanh Tung Dao / Nam Thang Nguyen / Thi Thuy Vu / Duc Thanh Nguyen / Duy Cuong Nguyen / Nang Trong Hoang / Thanh Liem Vu / Thi Minh Chinh Nguyen / Philippe Minodier / Philippe Gautret

    Journal of Epidemiology and Global Health, Vol 11, Iss

    A Five-year Descriptive Study with a Focus on Infectious Diseases

    2020  Volume 1

    Abstract: The objective of this study was to describe the overall pattern of morbidity and mortality of children seen at the Thai Binh Paediatric Hospital in Vietnam, with a focus on infectious diseases. A retrospective review of hospitalisation records was ... ...

    Abstract The objective of this study was to describe the overall pattern of morbidity and mortality of children seen at the Thai Binh Paediatric Hospital in Vietnam, with a focus on infectious diseases. A retrospective review of hospitalisation records was conducted from 1 January 2015 to 31 December 2019. Data were obtained from a total of 113,999 records. The median age of patients was 18 months, with 84.0% of patients aged <5 years. Infectious diseases accounted for 61.0% of all cases. The most prevalent diseases were lower respiratory tract infections (32.8%), followed by gastrointestinal infections (13.3%) and confirmed influenza (5.4%). Most infections were not microbiologically documented. A total of 81.4% patients received at least one antibiotic. Most patients (97.0%) were hospitalised for less than 15 days. Regarding outcomes, 87.8% patients were discharged home with a favourable outcome. Twelve percent were transferred to the Vietnam National Children’s Hospital because their condition had worsened and 0.1% died. In total, infectious diseases accounted for 40.4% of deaths, followed by neonatal disorders (34.6%). Our data serves a basis for the identification of needs for diagnostic tools and for future evaluation of the effect of the targeted implementation of such facilities. Point-of-care tests, including real-time polymerase chain reaction assays to identify common pathogens should be implemented for more accurate diagnosis and more appropriate antibiotic use.
    Keywords Children ; infectious disease ; lower respiratory tract infections ; gastrointestinal infections ; influenza ; Thai Binh ; Public aspects of medicine ; RA1-1270
    Subject code 610
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Springer
    Document type Article ; Online
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  6. Article ; Online: The impact of albendazole treatment on the incidence of viral- and bacterial-induced diarrhea in school children in southern Vietnam: study protocol for a randomized controlled trial.

    Leung, Jacqueline M / Hong, Chau Tran Thi / Trung, Nghia Ho Dang / Thi, Hoa Nhu / Minh, Chau Nguyen Ngoc / Thi, Thuy Vu / Hong, Dinh Thanh / Man, Dinh Nguyen Huy / Knowles, Sarah C L / Wolbers, Marcel / Hoang, Nhat Le Thanh / Thwaites, Guy / Graham, Andrea L / Baker, Stephen

    Trials

    2016  Volume 17, Issue 1, Page(s) 279

    Abstract: Background: Anthelmintics are one of the more commonly available classes of drugs to treat infections by parasitic helminths (especially nematodes) in the human intestinal tract. As a result of their cost-effectiveness, mass school-based deworming ... ...

    Abstract Background: Anthelmintics are one of the more commonly available classes of drugs to treat infections by parasitic helminths (especially nematodes) in the human intestinal tract. As a result of their cost-effectiveness, mass school-based deworming programs are becoming routine practice in developing countries. However, experimental and clinical evidence suggests that anthelmintic treatments may increase susceptibility to other gastrointestinal infections caused by bacteria, viruses, or protozoa. Hypothesizing that anthelmintics may increase diarrheal infections in treated children, we aim to evaluate the impact of anthelmintics on the incidence of diarrheal disease caused by viral and bacterial pathogens in school children in southern Vietnam.
    Methods/design: This is a randomized, double-blinded, placebo-controlled trial to investigate the effects of albendazole treatment versus placebo on the incidence of viral- and bacterial-induced diarrhea in 350 helminth-infected and 350 helminth-uninfected Vietnamese school children aged 6-15 years. Four hundred milligrams of albendazole, or placebo treatment will be administered once every 3 months for 12 months. At the end of 12 months, all participants will receive albendazole treatment. The primary endpoint of this study is the incidence of diarrheal disease assessed by 12 months of weekly active and passive case surveillance. Secondary endpoints include the prevalence and intensities of helminth, viral, and bacterial infections, alterations in host immunity and the gut microbiota with helminth and pathogen clearance, changes in mean z scores of body weight indices over time, and the number and severity of adverse events.
    Discussion: In order to reduce helminth burdens, anthelmintics are being routinely administered to children in developing countries. However, the effects of anthelmintic treatment on susceptibility to other diseases, including diarrheal pathogens, remain unknown. It is important to monitor for unintended consequences of drug treatments in co-infected populations. In this trial, we will examine how anthelmintic treatment impacts host susceptibility to diarrheal infections, with the aim of informing deworming programs of any indirect effects of mass anthelmintic administrations on co-infecting enteric pathogens.
    Trial registration: ClinicalTrials.gov: NCT02597556 . Registered on 3 November 2015.
    Language English
    Publishing date 2016-06-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2040523-6
    ISSN 1745-6215 ; 1468-6694 ; 1468-6708
    ISSN (online) 1745-6215 ; 1468-6694
    ISSN 1468-6708
    DOI 10.1186/s13063-016-1406-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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