Article ; Online: Recently activated CD4 T cells in tuberculosis express OX40 as a target for host-directed immunotherapy.
2023 Volume 14, Issue 1, Page(s) 8423
Abstract: After Mycobacterium tuberculosis (Mtb) infection, many effector T cells traffic to the lungs, but few become activated. Here we use an antigen receptor reporter mouse (Nur77-GFP) to identify recently activated CD4 T cells in the lungs. These Nur77- ... ...
Abstract | After Mycobacterium tuberculosis (Mtb) infection, many effector T cells traffic to the lungs, but few become activated. Here we use an antigen receptor reporter mouse (Nur77-GFP) to identify recently activated CD4 T cells in the lungs. These Nur77-GFP |
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MeSH term(s) | Humans ; Mice ; Animals ; CD4-Positive T-Lymphocytes ; Receptors, OX40/agonists ; CD8-Positive T-Lymphocytes ; Immunotherapy ; Tuberculosis/therapy |
Chemical Substances | Receptors, OX40 |
Language | English |
Publishing date | 2023-12-19 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 2553671-0 |
ISSN | 2041-1723 ; 2041-1723 |
ISSN (online) | 2041-1723 |
ISSN | 2041-1723 |
DOI | 10.1038/s41467-023-44152-8 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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