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  1. Article: A Call to Reinvent Platelet Products.

    Handtke, Stefan / Thiele, Thomas

    Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

    2024  Volume 51, Issue 2, Page(s) 63–65

    Language English
    Publishing date 2024-02-07
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2100848-6
    ISSN 1660-3818 ; 1660-3796
    ISSN (online) 1660-3818
    ISSN 1660-3796
    DOI 10.1159/000536237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Thesis: Moderne Proteomanalyseverfahren in der Transfusionsmedizin als Mittel zur Qualitätskontrolle von Blutprodukten

    Thiele, Thomas

    2008  

    Author's details vorgelegt von: Thomas Thiele
    Subject code 615.3
    Language German ; English
    Size 78 Bl., Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Greifswald, Univ., Diss., 2008
    HBZ-ID HT016101289
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Sicherheit in der Transfusionsmedizin

    Thiele, Thomas / Oldenburg, Johannes / Eichler, Hermann / Nauck, Matthias

    Neubewertung von Maßnahmen zur Reduktion des Risikos transfusionsassoziierter Infektionen

    2018  

    Institution Ernst-Moritz-Arndt-Universität Greifswald
    Author's details vorgelegt von Dr. med. Thomas Thiele
    Language German ; English
    Size 47 Blätter, 58 verschieden gezählte Blätter, Illustrationen, 30 cm
    Publishing place Greifswald
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Habilitationsschrift, Universitätsmedizin Greifswald, 2018
    HBZ-ID HT020083002
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Perioperatives Management der oralen Antikoagulation

    Thiele, Thomas / Langer, Florian

    Allgemein- und Viszeralchirurgie up2date

    2024  Volume 18, Issue 01, Page(s) 17–26

    Language German
    Publishing date 2024-03-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2317051-7
    ISSN 1611-6461 ; 1611-6437
    ISSN (online) 1611-6461
    ISSN 1611-6437
    DOI 10.1055/a-2225-8914
    Database Thieme publisher's database

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  5. Article ; Online: COAT Platelets Under Alarm.

    Thiele, Thomas / Handtke, Stefan

    Thrombosis and haemostasis

    2021  Volume 121, Issue 10, Page(s) 1267

    MeSH term(s) Blood Platelets ; Humans ; Platelet Activation ; Thrombin
    Chemical Substances Thrombin (EC 3.4.21.5)
    Language English
    Publishing date 2021-08-24
    Publishing country Germany
    Document type Journal Article ; Comment
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/s-0041-1735190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Anticoagulation in Patients with Platelet Disorders.

    Zaninetti, Carlo / Thiele, Thomas

    Hamostaseologie

    2021  Volume 41, Issue 2, Page(s) 112–119

    Abstract: Platelet disorders comprise heterogeneous diseases featured by reduced platelet counts and/or impaired platelet function causing variable bleeding symptoms. Despite their bleeding diathesis, patients with platelet disorders can develop transient or ... ...

    Abstract Platelet disorders comprise heterogeneous diseases featured by reduced platelet counts and/or impaired platelet function causing variable bleeding symptoms. Despite their bleeding diathesis, patients with platelet disorders can develop transient or permanent prothrombotic conditions that necessitate prophylactic or therapeutic anticoagulation. Anticoagulation in patients with platelet disorders is a matter of concern because the bleeding risk could add to the hemorrhagic risk related to the platelet defect. This review provides an overview on the evidence on anticoagulation in patients with acquired and inherited thrombocytopenia and/or platelet dysfunction. We summarize tools to evaluate and balance bleeding- and thrombotic risks and describe a practical approach on how to manage these patients if they have an indication for prophylactic or therapeutic anticoagulation.
    MeSH term(s) Anticoagulants/pharmacology ; Anticoagulants/therapeutic use ; Blood Platelet Disorders/drug therapy ; Hemorrhagic Disorders/drug therapy ; Humans ; Thrombocytopenia/metabolism
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2021-04-15
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 801512-0
    ISSN 2567-5761 ; 0720-9355
    ISSN (online) 2567-5761
    ISSN 0720-9355
    DOI 10.1055/a-1344-7279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Platelet size as a mirror for the immune response after SARS-CoV-2 vaccination.

    Thiele, Thomas / Schwarz, Silas L / Handtke, Stefan

    Journal of thrombosis and haemostasis : JTH

    2022  Volume 20, Issue 4, Page(s) 818–820

    MeSH term(s) COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; Immunity ; SARS-CoV-2 ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-02-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.15659
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Large and small platelets-(When) do they differ?

    Handtke, Stefan / Thiele, Thomas

    Journal of thrombosis and haemostasis : JTH

    2020  Volume 18, Issue 6, Page(s) 1256–1267

    Abstract: Platelets are most important in providing cellular hemostasis but also take part in inflammation and immune processes. Increased platelet size has been regarded as a feature describing a young and more reactive subpopulation until studies were published ... ...

    Abstract Platelets are most important in providing cellular hemostasis but also take part in inflammation and immune processes. Increased platelet size has been regarded as a feature describing a young and more reactive subpopulation until studies were published which questioned this concept. Moreover, changes of platelet size given by the mean platelet volume (MPV) were described for immune thrombocytopenia, cardiovascular disease, atherosclerosis, venous thromboembolism, chronic lung disease, sepsis, cancer-associated thrombosis, autoimmune disorders, and others. This review summarizes the literature on what is known about platelets with different size and describes controversies of studies with large and small platelets putting a focus on their thrombogenicity, age, and on the association of MPV with the mentioned diseases.
    MeSH term(s) Blood Platelets ; Hemostasis ; Humans ; Mean Platelet Volume ; Thrombocytopenia ; Thrombosis
    Language English
    Publishing date 2020-04-09
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.14788
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: An anti-PF4 antibody-related disorder with cerebral venous sinus thrombosis and thrombocytopenia initially presenting as intracranial hemorrhage.

    Wittstock, Matthias / Cantré, Daniel / Won, Sae-Yeon / Jürs, Alexandra V / Wesche, Jan / Greger, Nico / Greinacher, Andreas / Thiele, Thomas

    Journal of neurology

    2024  

    Language English
    Publishing date 2024-04-10
    Publishing country Germany
    Document type Letter
    ZDB-ID 187050-6
    ISSN 1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    ISSN (online) 1432-1459
    ISSN 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    DOI 10.1007/s00415-024-12373-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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