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  1. Article ; Online: SRSF1, a splicing-factor oncoprotein: Prospective biomarker and therapeutic target for oral cancer.

    Thiruvengadam, Rekha / Thiruvengadam, Muthu

    Journal of stomatology, oral and maxillofacial surgery

    2024  Volume 125, Issue 6, Page(s) 101800

    Language English
    Publishing date 2024-02-16
    Publishing country France
    Document type Editorial
    ZDB-ID 2916276-2
    ISSN 2468-7855 ; 2468-8509
    ISSN (online) 2468-7855
    ISSN 2468-8509
    DOI 10.1016/j.jormas.2024.101800
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  2. Article ; Online: Role of Natural Nuclear Factor Erythroid-2-related Factor 2 (Nrf2) Activators in Oral and Head and Neck Cancer Treatment.

    Rekha, Kaliaperumal / Thiruvengadam, Muthu

    Current cancer drug targets

    2023  Volume 23, Issue 6, Page(s) 425–427

    MeSH term(s) Humans ; NF-E2-Related Factor 2/metabolism ; Head and Neck Neoplasms/drug therapy ; Oxidative Stress
    Chemical Substances NF-E2-Related Factor 2
    Language English
    Publishing date 2023-01-20
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2064824-8
    ISSN 1873-5576 ; 1568-0096
    ISSN (online) 1873-5576
    ISSN 1568-0096
    DOI 10.2174/1568009623666230220121725
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5589: Show issues Location:
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  3. Article ; Online: Impact of nanopollution on plant growth, photosynthesis, toxicity, and metabolism in the agricultural sector: An updated review.

    Thiruvengadam, Muthu / Chi, Hee Youn / Kim, Seung-Hyun

    Plant physiology and biochemistry : PPB

    2024  Volume 207, Page(s) 108370

    Abstract: Nanotechnology provides distinct benefits to numerous industrial and commercial fields, and has developed into a discipline of intense interest to researchers. Nanoparticles (NPs) have risen to prominence in modern agriculture due to their use in ... ...

    Abstract Nanotechnology provides distinct benefits to numerous industrial and commercial fields, and has developed into a discipline of intense interest to researchers. Nanoparticles (NPs) have risen to prominence in modern agriculture due to their use in agrochemicals, nanofertilizers, and nanoremediation. However, their potential negative impacts on soil and water ecosystems, as well as plant growth and physiology, have caused concern for researchers and policymakers. Concerns have been expressed regarding the ecological consequences and toxicity effects associated with nanoparticles as a result of their increased production and usage. Moreover, the accumulation of nanoparticles in the environment poses a risk, not only because of the possibility of plant damage but also because nanoparticles may infiltrate the food chain. In this review, we have documented the beneficial and detrimental effects of NPs on seed germination, shoot and root growth, plant biomass, and nutrient assimilation. Nanoparticles exert toxic effects by inducing ROS generation and stimulating cytotoxic and genotoxic effects, thereby leading to cell death in several plant species. We have provided possible mechanisms by which nanoparticles induce toxicity in plants. In addition to the toxic effects of NPs, we highlighted the importance of nanomaterials in the agricultural sector. Thus, understanding the structure, size, and concentration of nanoparticles that will improve plant growth or induce plant cell death is essential. This updated review reveals the multifaceted connection between nanoparticles, soil and water pollution, and plant biology in the context of agriculture.
    MeSH term(s) Ecosystem ; Plant Development ; Nanoparticles/toxicity ; Photosynthesis ; Agriculture ; Plants ; Soil
    Chemical Substances Soil
    Language English
    Publishing date 2024-01-14
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 742978-2
    ISSN 1873-2690 ; 0981-9428
    ISSN (online) 1873-2690
    ISSN 0981-9428
    DOI 10.1016/j.plaphy.2024.108370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 2696: Show issues
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  4. Article ; Online: Phytochemicals from Natural Products for the Prevention and Treatment of Non-communicable Diseases.

    Keskin, Merve / Thiruvengadam, Muthu

    Current topics in medicinal chemistry

    2022  Volume 22, Issue 23, Page(s) 1907–1908

    MeSH term(s) Humans ; Biological Products/pharmacology ; Noncommunicable Diseases/drug therapy ; Noncommunicable Diseases/prevention & control ; Phytochemicals/pharmacology ; Phytochemicals/therapeutic use
    Chemical Substances Biological Products ; Phytochemicals
    Language English
    Publishing date 2022-11-13
    Publishing country United Arab Emirates
    Document type Editorial
    ZDB-ID 2064823-6
    ISSN 1873-4294 ; 1568-0266
    ISSN (online) 1873-4294
    ISSN 1568-0266
    DOI 10.2174/156802662223221019141622
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5572: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  5. Article ; Online: Synthesis, Bioactivity Evaluation and Application of Plant-Based Nanoparticles.

    Rajakumar, Govindasamy / Sudha, Parappurath Narayanan / Thiruvengadam, Muthu

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 12

    Abstract: Environmental and biomedical fields have various potential applications for the green synthesis of nanoparticles [ ... ]. ...

    Abstract Environmental and biomedical fields have various potential applications for the green synthesis of nanoparticles [...].
    MeSH term(s) Metal Nanoparticles ; Green Chemistry Technology ; Nanoparticles ; Plants
    Language English
    Publishing date 2023-06-15
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28124783
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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  6. Article ; Online: Current Strategies for Overcoming Smoking Addiction: A Major Cause of Oral Cancer.

    Govindasamy, Rajakumar / Venkidasamy, Baskar / Thiruvengadam, Muthu

    Recent patents on anti-cancer drug discovery

    2023  Volume 19, Issue 2, Page(s) 123–125

    MeSH term(s) Humans ; Smoking/adverse effects ; Tobacco Use Disorder ; Tobacco Smoking ; Mouth Neoplasms/etiology
    Language English
    Publishing date 2023-02-17
    Publishing country United Arab Emirates
    Document type Editorial
    ZDB-ID 2250820-X
    ISSN 2212-3970 ; 1574-8928
    ISSN (online) 2212-3970
    ISSN 1574-8928
    DOI 10.2174/1574892818666230220120507
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6393: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article ; Online: A comprehensive review on tissue culture studies and secondary metabolite production in Bacopa monnieri L. Pennell: a nootropic plant

    Sudheer, W. N. / Thiruvengadam, Muthu / Nagella, Praveen

    Critical Reviews in Biotechnology. 2023 Aug. 18, v. 43, no. 6 p.956-970

    2023  

    Abstract: Bacopa monnieri L. Pennell, commonly known as Brahmi, is an important medicinal plant that belongs to the family Plantaginaceae. Brahmi is rich in innumerable bioactive secondary metabolites, especially bacosides that can be employed to reduce many ... ...

    Abstract Bacopa monnieri L. Pennell, commonly known as Brahmi, is an important medicinal plant that belongs to the family Plantaginaceae. Brahmi is rich in innumerable bioactive secondary metabolites, especially bacosides that can be employed to reduce many health issues. This plant is used as a neuro-tonic and treatment for mental health, depression, and cognitive performance. Brahmi is also known for its antioxidant, anti-inflammatory, and anti-hepatotoxic activities. There is a huge demand for its raw materials, particularly for the extraction of bioactive molecules. The conventional mode of propagation could not meet the required commercial demand. To overcome this, biotechnological approaches, such as plant tissue culture techniques have been established for the production of important secondary metabolites through various culture techniques, such as callus and cell suspension cultures and organ cultures, to allow for rapid propagation and conservation of medicinally important plants with increased production of bioactive compounds. It has been found that a bioreactor-based technology can also enhance the multiplication rate of cell and organ cultures for commercial propagation of medicinally important bioactive molecules. The present review focuses on the propagation and production of bacoside A by cell and organ cultures of Bacopa monnieri, a nootropic plant. The review also focuses on the biosynthesis of bacoside A, different elicitation strategies, and the over-expression of genes for the production of bacoside-A. It also identifies research gaps that need to be addressed in future studies for the sustainable production of bioactive molecules from B. monnieri.
    Keywords Bacopa monnieri ; antioxidants ; biosynthesis ; biotechnology ; callus ; cognition ; medicinal plants ; mental health ; secondary metabolites ; tissue culture ; Agrobacterium rhizogenes ; bacoside A ; multiple shoot culture ; plant cell culture
    Language English
    Dates of publication 2023-0818
    Size p. 956-970.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 1042364-3
    ISSN 1549-7801 ; 0738-8551
    ISSN (online) 1549-7801
    ISSN 0738-8551
    DOI 10.1080/07388551.2022.2085544
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2554: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Nano-based biofuel production from low-cost lignocellulose biomass: environmental sustainability and economic approach.

    Sakthivel, Selvakumar / Muthusamy, Kanthimathi / Thangarajan, Amutha Priya / Thiruvengadam, Muthu / Venkidasamy, Baskar

    Bioprocess and biosystems engineering

    2024  

    Abstract: The use of nanomaterials in biofuel production from lignocellulosic biomass offers a promising approach to simultaneously address environmental sustainability and economic viability. This review provides an overview of the environmental and economic ... ...

    Abstract The use of nanomaterials in biofuel production from lignocellulosic biomass offers a promising approach to simultaneously address environmental sustainability and economic viability. This review provides an overview of the environmental and economic implications of integrating nanotechnology into biofuel production from low-cost lignocellulosic biomass. In this review, we highlight the potential benefits and challenges of nano-based biofuel production. Nanomaterials provide opportunities to improve feedstock pretreatment, enzymatic hydrolysis, fermentation, and catalysis, resulting in enhanced process efficiency, lower energy consumption, and reduced environmental impact. Conducting life cycle assessments is crucial for evaluating the overall environmental footprint of biofuel production. An economic perspective that focuses on the cost implications of utilizing nanomaterials in biofuel production is also discussed. A comprehensive understanding of both environmental and economic dimensions is essential to fully harness the potential of nanomaterials in biofuel production from lignocellulosic biomass and to move towards sustainable future energy.
    Language English
    Publishing date 2024-03-30
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1476357-6
    ISSN 1615-7605 ; 1432-0797 ; 1615-7591
    ISSN (online) 1615-7605 ; 1432-0797
    ISSN 1615-7591
    DOI 10.1007/s00449-024-03005-4
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  9. Article ; Online: Nanotechnology Approaches for the Remediation of Agricultural Polluted Soils.

    Dhanapal, Anand Raj / Thiruvengadam, Muthu / Vairavanathan, Jayavarshini / Venkidasamy, Baskar / Easwaran, Maheswaran / Ghorbanpour, Mansour

    ACS omega

    2024  Volume 9, Issue 12, Page(s) 13522–13533

    Abstract: Soil pollution from various anthropogenic and natural activities poses a significant threat to the environment and human health. This study explored the sources and types of soil pollution and emphasized the need for innovative remediation approaches. ... ...

    Abstract Soil pollution from various anthropogenic and natural activities poses a significant threat to the environment and human health. This study explored the sources and types of soil pollution and emphasized the need for innovative remediation approaches. Nanotechnology, including the use of nanoparticles, is a promising approach for remediation. Diverse types of nanomaterials, including nanobiosorbents and nanobiosurfactants, have shown great potential in soil remediation processes. Nanotechnology approaches to soil pollution remediation are multifaceted. Reduction reactions and immobilization techniques demonstrate the versatility of nanomaterials in mitigating soil pollution. Nanomicrobial-based bioremediation further enhances the efficiency of pollutant degradation in agricultural soils. A literature-based screening was conducted using different search engines, including PubMed, Web of Science, and Google Scholar, from 2010 to 2023. Keywords such as "soil pollution, nanotechnology, nanoremediation, heavy metal remediation, soil remediation" and combinations of these were used. The remediation of heavy metals using nanotechnology has demonstrated promising results and offers an eco-friendly and sustainable solution to address this critical issue. Nanobioremediation is a robust strategy for combatting organic contamination in soils, including pesticides and herbicides. The use of nanophytoremediation, in which nanomaterials assist plants in extracting and detoxifying pollutants, represents a cutting-edge and environmentally friendly approach for tackling soil pollution.
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c09776
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  10. Article ; Online: Antimicrobial activity of probiotic bacteria-mediated cadmium oxide nanoparticles against fish pathogens.

    Rajeshkumar, Shanmugam / Jayakodi, Santhoshkumar / Tharani, M / Alharbi, Naiyf S / Thiruvengadam, Muthu

    Microbial pathogenesis

    2024  Volume 189, Page(s) 106602

    Abstract: The current research was designed to investigate the antibacterial activity of probiotic bacteria mediated cadmium oxide nanoparticles (CdO NPs) on common fish pathogenic bacteria like Serratia marcescens, Aeromonas hydrophila, Vibrio harveyi, and V. ... ...

    Abstract The current research was designed to investigate the antibacterial activity of probiotic bacteria mediated cadmium oxide nanoparticles (CdO NPs) on common fish pathogenic bacteria like Serratia marcescens, Aeromonas hydrophila, Vibrio harveyi, and V. parahaemolyticus. CdO NPs were synthesized using probiotic bacteria as follows: Lactobacillus species with different precursor of cadmium sulfate concentrations (5, 10, and 20 mM). The average crystalline sizes of the CdO NPs were determined based on the XRD patterns using the Debye-Scherrer equation for different precursor concentrations. Specifically, sizes of 40, 48, and 67 nm were found at concentrations of 5, 10, and 20 mM, respectively. The antibacterial efficacy of CdO NPs was estimated using a well diffusion assay, which demonstrated the best efficacy of 20 mM CdO NPs against all pathogens. AFM analysis of nanoparticle-treated and untreated biofilms was performed to further validate the antibacterial effect. Antibacterial activity of CdO nanoparticles synthesized at varying concentrations (5, 10, and 20 mM) against fish pathogens (S. marcescens, A. hydrophila, V. harveyi, and V. parahaemolyticus). The results indicated the highest inhibitory effect of 20 mM CdO NPs across all concentrations (30, 60, and 90 μg/mL), demonstrating significant inhibition against S. marcescens. These findings will contribute to the development of novel strategies for combating aquatic diseases and advancing aquaculture health management practices.
    MeSH term(s) Animals ; Oxides/chemistry ; Nanoparticles/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Bacteria ; Fishes ; Metal Nanoparticles/chemistry ; Cadmium Compounds
    Chemical Substances cadmium oxide (0H3KWS8KJ3) ; Oxides ; Anti-Bacterial Agents ; Cadmium Compounds
    Language English
    Publishing date 2024-02-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2024.106602
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2136: Show issues Location:
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