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Article ; Online: Repetitive negative thinking as a unique transdiagnostic risk factor for suicidal ideation.

Caudle, M M / Dugas, N N / Patel, K / Moore, R C / Thomas, M L / Bomyea, J

2024 Volume 334, Page(s) 115787

Abstract: Repetitive negative thinking (RNT) is a transdiagnostic symptom observed across mood and anxiety disorders and is characterized by frequent, distressing thoughts that are perceived as uncontrollable. Specific forms of RNT have been linked to increased ... ...

Abstract	Repetitive negative thinking (RNT) is a transdiagnostic symptom observed across mood and anxiety disorders and is characterized by frequent, distressing thoughts that are perceived as uncontrollable. Specific forms of RNT have been linked to increased suicide risk. However, most work examining links between RNT and suicide has been conducted within specific disorders and subtypes of RNT (e.g., rumination in individuals with depression). The present study aimed to investigate associations between transdiagnostic RNT and suicidal ideation. We hypothesized RNT would be associated with suicide risk beyond disorder-specific clinical symptoms. Fifty-four participants with mood, anxiety, and/or traumatic stress disorders completed an interview assessing suicidal risk (Columbia-Suicide Severity Rating Scale (C-SSRS)) and self-report questionnaires assessing transdiagnostic RNT, depression, and anxiety. Based on C-SSRS, we divided participants into high or low suicide risk groups. We analyzed the relationship between suicidal risk group and RNT and found that RNT was uniquely associated with suicidal risk group, controlling for depression and anxiety severity. Our results suggest including assessments of RNT may have clinical utility for understanding the degree of suicide risk in individuals and point to the potential utility of including clinical interventions to target this symptom for those at high risk of suicide.
MeSH term(s)	Humans ; Pessimism ; Suicidal Ideation ; Anxiety/diagnosis ; Anxiety Disorders ; Surveys and Questionnaires ; Risk Factors
Language	English
Publishing date	2024-02-13
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	445361-x
ISSN	1872-7123 ; 1872-7506 ; 0925-4927 ; 0165-1781
ISSN (online)	1872-7123 ; 1872-7506
ISSN	0925-4927 ; 0165-1781
DOI	10.1016/j.psychres.2024.115787
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Article ; Online: Validity of sagittal thoracolumbar curvature measurement using a non-radiographic surface topography method.

Hannink, Erin / Dawes, Helen / Shannon, Thomas M L / Barker, Karen L

Spine deformity

2022 Volume 10, Issue 6, Page(s) 1299–1306

Abstract: Purpose: To estimate the criterion validity of sagittal thoracolumbar spine measurement using a surface topography method in a clinical population against the gold standard and to estimate concurrent validity against two non-radiographic clinical tools.! ...

Abstract	Purpose: To estimate the criterion validity of sagittal thoracolumbar spine measurement using a surface topography method in a clinical population against the gold standard and to estimate concurrent validity against two non-radiographic clinical tools. Methods: In this cross-sectional validity study, thoracolumbar curvature was measured in adults with spinal conditions recruited from a specialist orthopaedic hospital. A surface topography method using a Kinect sensor was compared to three other measurement methods: spinal radiograph (gold standard), flexicurve and digital inclinometer. Correlation coefficients and agreement between the measurement tools were analysed. Results: Twenty-nine participants (79% female) were included in criterion validity analyses and 38 (76% female) in concurrent validity analyses. The surface topography method was moderately correlated with the radiograph (r = .70, p < .001) in the thoracic spine, yet there was no significant correlation with the radiograph in the lumbar spine (r = .32, p = .89). The surface topography method was highly correlated with the flexicurve (r Conclusions: The surface topography method showed moderate correlation and agreement in thoracic spine with the radiograph (criterion validity) and high correlation with the flexicurve and digital inclinometer (concurrent validity). Compared with other non-radiographic tools, this surface topography method displayed similar criterion validity for kyphosis curvature measurement.
MeSH term(s)	Adult ; Humans ; Female ; Male ; Cross-Sectional Studies ; Reproducibility of Results ; Kyphosis/diagnostic imaging ; Lumbar Vertebrae/diagnostic imaging ; Radiography
Language	English
Publishing date	2022-07-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2717704-X
ISSN	2212-1358 ; 2212-134X ; 2212-1358
ISSN (online)	2212-1358 ; 2212-134X
ISSN	2212-1358
DOI	10.1007/s43390-022-00538-0
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Article: Arthroscopic Latarjet Procedure Using FiberTape Cerclage With a Simplified Technique for Suture Passage and Coracoid Fixation.

Jos, Sujit / Sanu, Shankar / J, Antony / Thomas M, Libin / Paulose, Bobby

Arthroscopy techniques

2022 Volume 11, Issue 7, Page(s) e1277–e1287

Abstract: Arthroscopic Latarjet has evolved as a reproducible procedure to address significant anterior glenoid bone loss in recurrent anterior instability of the shoulder joint. While arthroscopic Bankart procedure for anterior shoulder instability has changed ... ...

Abstract	Arthroscopic Latarjet has evolved as a reproducible procedure to address significant anterior glenoid bone loss in recurrent anterior instability of the shoulder joint. While arthroscopic Bankart procedure for anterior shoulder instability has changed from metal anchors to absorbable or soft all-suture anchors to avoid metal-ware and subsequent abrasion in cases of osteolysis or backout, Latarjet procedure, until recently couple of titanium screws were used to fix the coracoid bone to the anterior glenoid. Arthroscopic techniques for Latarjet procedure of coracoid bone transfer have shown results similar to the open technique in many recent studies. We use an all-arthroscopic technique that is different and easier from the currently described technique using FiberTape cerclage loops, with 2 ultrabraid tapes fixing the coracoid bone to the prepared anteroinferior glenoid surface. The repair is completed using all-suture anchors to fix the anterior capsule over the attached coracoid, thus exteriorizing the transferred bone and preventing contact with the moving humeral head.
Language	English
Publishing date	2022-06-21
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2653101-X
ISSN	2212-6287
ISSN	2212-6287
DOI	10.1016/j.eats.2022.03.011
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Article: Ischæmic diseases of the colon [abridged].

Thomas, M L

Proceedings of the Royal Society of Medicine

2010 Volume 59, Issue 9, Page(s) 887–889

Language	English
Publishing date	2010-10-04
Publishing country	England
Document type	Journal Article
ZDB-ID	209243-8
ISSN	0035-9157
ISSN	0035-9157
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Article ; Online: Impact of timing of reversal of loop ileostomy on patient outcomes: a retrospective cohort study.

Khoo, T-W / Dudi-Venkata, N N / Beh, Y Z / Bedrikovetski, S / Kroon, H M / Thomas, M L / Sammour, T

Techniques in coloproctology

2021 Volume 25, Issue 11, Page(s) 1217–1224

Abstract: Background: Diverting loop ileostomies (DLIs) are ideally reversed 6-12 weeks after the index operation. However, reversal surgery is frequently delayed in a real-world setting, with potential implications on patient's quality of life and postoperative ... ...

Abstract	Background: Diverting loop ileostomies (DLIs) are ideally reversed 6-12 weeks after the index operation. However, reversal surgery is frequently delayed in a real-world setting, with potential implications on patient's quality of life and postoperative complications. The aim of this study was to investigate the impact of timing of the reversal on patient outcomes at a tertiary referral hospital. Methods: Consecutive patients who underwent elective reversal of loop ileostomy (RLI) between January 2007 and January 2019 were included. The primary outcomes were incidence of postoperative ileus (POI) and 30-day postoperative complications. Results: Of 251 eligible patients, 158 (63%) were men, the median age was 64 years (range 23-88 years), and the most common index operation was an ultra-low anterior resection in 106 (42%). The median time to reversal for the entire cohort was 7.4 months (range 1-28). RLI was performed within 6 months after the index surgery in 89 patients (35%, early group), 6-12 months in 120 (48%, middle group) and after more than 12 months in 42 (17%, late group) patients. A significantly lower incidence of postoperative ileus (13.5% vs. 25.8% vs. 38.1%, p = 0.006), and 30-day postoperative complications (29.2% vs 41.7% vs. 57.1%, p = 0.011) were seen in the early group compared to the middle and late groups, respectively. There was no difference in the return to theater, length of hospital stay, and readmission rate between groups. Conclusion: Delayed RLI is associated with increased risk of postoperative complications.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Ileostomy/adverse effects ; Length of Stay ; Male ; Middle Aged ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Quality of Life ; Retrospective Studies ; Young Adult
Language	English
Publishing date	2021-09-09
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2083309-X
ISSN	1128-045X ; 1123-6337
ISSN (online)	1128-045X
ISSN	1123-6337
DOI	10.1007/s10151-021-02516-6
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Zs.A 5842: Show issues

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Article ; Online: Safety and efficacy of laxatives after major abdominal surgery: systematic review and meta-analysis.

Dudi-Venkata, N N / Seow, W / Kroon, H M / Bedrikovetski, S / Moore, J W / Thomas, M L / Sammour, T

BJS open

2020 Volume 4, Issue 4, Page(s) 577–586

Abstract: Background: Recovery of gastrointestinal function is often delayed after major abdominal surgery, leading to postoperative ileus (POI). Enhanced recovery protocols recommend laxatives to reduce the duration of POI, but evidence is unclear. This ... ...

Abstract	Background: Recovery of gastrointestinal function is often delayed after major abdominal surgery, leading to postoperative ileus (POI). Enhanced recovery protocols recommend laxatives to reduce the duration of POI, but evidence is unclear. This systematic review aimed to assess the safety and efficacy of laxative use after major abdominal surgery. Methods: Ovid MEDLINE, Embase, Cochrane Library and PubMed databases were searched from inception to May 2019 to identify eligible RCTs focused on elective open or minimally invasive major abdominal surgery. The primary outcome was time taken to passage of stool. Secondary outcomes were time taken to tolerance of diet, time taken to flatus, length of hospital stay, postoperative complications and readmission to hospital. Results: Five RCTs with a total of 416 patients were included. Laxatives reduced the time to passage of stool (mean difference (MD) -0·83 (95 per cent c.i. -1·39 to -0·26) days; P = 0·004), but there was significant heterogeneity between studies for this outcome measure. There was no difference in time to passage of flatus (MD -0·17 (-0·59 to 0·25) days; P = 0·432), time to tolerance of diet (MD -0·01 (-0·12 to 0·10) days; P = 0·865) or length of hospital stay (MD 0·01(-1·36 to 1·38) days; P = 0·992). There were insufficient data available on postoperative complications for meta-analysis. Conclusion: Routine postoperative laxative use after major abdominal surgery may result in earlier passage of stool but does not influence other postoperative recovery parameters. Better data are required for postoperative complications and validated outcome measures.
MeSH term(s)	Abdomen/surgery ; Data Management ; Defecation/drug effects ; Elective Surgical Procedures/adverse effects ; Humans ; Ileus/prevention & control ; Laxatives/pharmacology ; Postoperative Complications/prevention & control ; Randomized Controlled Trials as Topic ; Time Factors
Chemical Substances	Laxatives
Language	English
Publishing date	2020-05-27
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
ISSN	2474-9842
ISSN (online)	2474-9842
DOI	10.1002/bjs5.50301
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Article ; Online: Crickets detect the genetic similarity of mating partners via cuticular hydrocarbons.

Thomas, M L / Simmons, L W

Journal of evolutionary biology

2011 Volume 24, Issue 8, Page(s) 1793–1800

Abstract: Animals should decipher information about the genetic make-up of conspecifics in order to enhance the fitness benefits associated with mate choice. Although there is increasing evidence to suggest that animals make genetically informed decisions about ... ...

Abstract	Animals should decipher information about the genetic make-up of conspecifics in order to enhance the fitness benefits associated with mate choice. Although there is increasing evidence to suggest that animals make genetically informed decisions about their mating partners, we understand relatively little about the sensory mechanisms informing these decisions. Here, we investigate whether cuticular hydrocarbons, chemical compounds found on the cuticle of most terrestrial arthropods, provide a means of discerning genetic similarity during mate choice in the cricket, Teleogryllus oceanicus. We found that individuals preferentially mated with partners who share more dissimilar cuticular hydrocarbon profiles and that similarity in cuticular hydrocarbon profiles between mating pairs correlated with their genetic similarity. Our results provide good evidence that cuticular hydrocarbon profiles offer a means of assessing genetic compatibility in T. oceanicus, enabling individuals to choose their most genetically suitable mate.
MeSH term(s)	Animal Communication ; Animals ; Female ; Gryllidae/genetics ; Gryllidae/physiology ; Hydrocarbons/chemistry ; Male ; Mating Preference, Animal
Chemical Substances	Hydrocarbons
Language	English
Publishing date	2011-08
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1465318-7
ISSN	1420-9101 ; 1010-061X
ISSN (online)	1420-9101
ISSN	1010-061X
DOI	10.1111/j.1420-9101.2011.02319.x
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Article: Biphasic actions of estrogen on colon cancer cell growth: possible mediation by high- and low-affinity estrogen binding sites.

Xu, X / Thomas, M L

Endocrine

2010 Volume 3, Issue 9, Page(s) 661–665

Abstract: The present experiments were carried out to investigate the possible direct effects of estrogens (E) on the growth of colon cancer cells. Estradiol exhibited a concentration-dependent biphasic growth effect on a mouse colon cancer cell line (MC-26). Low ... ...

Abstract	The present experiments were carried out to investigate the possible direct effects of estrogens (E) on the growth of colon cancer cells. Estradiol exhibited a concentration-dependent biphasic growth effect on a mouse colon cancer cell line (MC-26). Low concentrations of estradiol (10(-10) M: to 10(-8) M: ) had a growth-stimulatory effect, while higher concentrations (10(-7) M: to 10(-6) M: ) were growth-inhibitory. Estrogen receptor (ER) mRNA as well as specific, saturable binding of estradiol to ER (K(d)=0.3NM: , B(max)=0.72 fmol/μg DNA) was identified in these cells. In addition to the classical high affinity ER, lower affinity, higher capacity estrogen binding sites (K(d)=35MM: , B(max)=30 fmol/μg DNA) were also characterized in MC-26 cells. These two types of estrogen binding sites exhibited distinct binding specificities for E and antiestrogens. Treatment of MC-26 cells with an oligodeoxy-nucleotide antisense to the translation start codon of ER mRNA did not alter the grown-inhibitory effect of 10(-6) M: estradiol, demonstrating that the growth-inhibitory effect of high concentrations of E was not mediated by ER; we have previously shown that under the same conditions, ER antisense oligonucleotides do block the growth-stimulatory effects of 10(-9) M: E(2) in MC-26 cells. The data suggest that physiological concentrations of estradiol acting via the classical ER may have a proliferative effect on the growth of colon cancer cells. However, in situations where there are high luminal concentrations of estrogenic compounds, they may act on low affinity estrogen binding sites that mediate the growth-inhibitory effect.
Language	English
Publishing date	2010-12-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	1194484-5
ISSN	1355-008X ; 0969-711X
ISSN	1355-008X ; 0969-711X
DOI	10.1007/BF02746342
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Article: Interactions of 1,25(OH)(2)D (3) and retinoic acid in the regulation of IEC-6 cell alkaline phosphatase activity.

Jeng, Y J / Thomas, M L

Endocrine

2010 Volume 3, Issue 2, Page(s) 101–105

Abstract: The goal of the present work was to use IEC-6 cells to investigate the possible mechanisms underlying the regulation of alkaline phosphatase (ALP) activity (ALPA) by 1α, 25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) and retinoids. Here we demonstrate that ... ...

Abstract	The goal of the present work was to use IEC-6 cells to investigate the possible mechanisms underlying the regulation of alkaline phosphatase (ALP) activity (ALPA) by 1α, 25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) and retinoids. Here we demonstrate that the vitamin D analogs, 25(OH)(2)-16-ene-23-yne-D(3) and 1α, 24S-(OH)(2)-22-en-26, 27-dehydro-vitamin D(3), which have been shown by others to bind to the intracellular vitamin D receptor (VDR), have similar effects to 1, 25(OH)(2)D(3) in increasing ALPA of IEC-6 cells. A third vitamin D analog, 25-(OH)-16-ene-23-yne-D(3) (AT), which activates membrane 1,25(OH)(2)D(3) effects, but binds poorly to the intracellular VDR, did not stimulate ALPA of IEC-6 cells. These data suggest that the effects of 1,25(OH)(2)D(3) to increase ALPA are mediated by intracellular VDR rather than by membrane actions of the hormone. The all-trans and 9-cis retinoic acids alone each caused increased ALPA of IEC-6 cells without altering steady-state levels of ALP mRNA, suggesting that retinoic acids may regulate ALPA of IEC-6 cells at a posttranscriptional level. Vitamin D analogs which bind intracellular receptors showed synergistic effects with either retinoid to increase ALPA, but there was no interaction with AT. Although the retinoids alone did not alter ALP mRNA levels, addition of 1,25(OH)(2)D(3) in combination with either retinoid increased ALP mRNA more than did 1,25(OH)(2)D(3) alone. These data suggest that the synergistic effects of 1,25(OH)(2)D(3) and retinoids on IEC-6 cell ALPA are mediated by intracellular VDR. The results of these experiments indicate that 1,25(OH)(2)D(3) alters IEC-6 cell ALPA via increased mRNA levels, while retinoids appear to both have post-transcriptional effects and the capacity to interact with 1,25(OH)(2)D(3) in altering ALP mRNA levels.
Language	English
Publishing date	2010-12-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	1194484-5
ISSN	1355-008X ; 0969-711X
ISSN	1355-008X ; 0969-711X
DOI	10.1007/BF02990060
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Article ; Online: Impact of STIMUlant and osmotic LAXatives (STIMULAX trial) on gastrointestinal recovery after colorectal surgery: randomized clinical trial.

Dudi-Venkata, N N / Kroon, H M / Bedrikovetski, S / Lewis, M / Lawrence, M J / Hunter, R A / Moore, J W / Thomas, M L / Sammour, T

The British journal of surgery

2021 Volume 108, Issue 10, Page(s) e357

Language	English
Publishing date	2021-10-22
Publishing country	England
Document type	Published Erratum
ZDB-ID	2985-3
ISSN	1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
ISSN (online)	1365-2168
ISSN	0263-1202 ; 0007-1323 ; 1355-7688
DOI	10.1093/bjs/znab252
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