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Article: Perceived Health Benefits in Vestibular Schwannoma Patients with Long-Term Postoperative Headache: Insights from Personality Traits and Pain Coping-A Cross-Sectional Study.

Thomas, Mareike / Führes, Hannah / Scheer, Maximilian / Rampp, Stefan / Strauss, Christian / Schönfeld, Robby / Leplow, Bernd

Journal of personalized medicine

2024 Volume 14, Issue 1

Abstract: Postoperative headaches (POHs) following retrosigmoid microsurgery for vestibular schwannoma (VS) can significantly impact patients' perceived health benefits (PHBs). In this cross-sectional observational study, 101 VS patients were investigated. For the ...

Abstract	Postoperative headaches (POHs) following retrosigmoid microsurgery for vestibular schwannoma (VS) can significantly impact patients' perceived health benefits (PHBs). In this cross-sectional observational study, 101 VS patients were investigated. For the assessment of pain, the Rostock Headache Compendium (RoKoKo) and the German pain processing questionnaire (FESV) were used. The perceived health benefits (PHBs) were assessed by the Glasgow Benefit Inventory (GBI) and Big Five personality traits were measured using the Ten-Item Personality Inventory (TIPI-G). We showed that 55% of the participants experienced POHs, leading to a marked reduction in overall PHBs compared to those without POHs. The correlation analysis revealed an association between decreased PHBs and elevated levels of pain-related helplessness, depression, anxiety, and anger. Positive correlations were identified between PHBs and action-planning competence, cognitive restructuring, and the experience of competence. Low emotional stability and openness yielded associations with pain-related psychological impairment. Hearing loss and facial paresis did not exert a significant impact on PHBs. The study highlights the influence of pain-related coping strategies on PHBs in long-term POH patients. Thus, coping mechanisms and personality traits should be assessed even before surgery for post-surgery pain prevention. The limitations of this study include a relatively small sample size, potential biases introduced by the overrepresentation of female patients, and the use of an online survey methodology. In conclusion, this research highlights that the interplay between headaches, PHBs, and psychological factors is also relevant in VS patients undergoing microsurgery. Short-term psychological interventions should therefore be taken into account to improve post-surgery adaptive coping strategies.
Language	English
Publishing date	2024-01-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm14010075
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Psycho-oncologists' experiences with video consultations during the Covid-19 pandemic and implications for the future-a multi-methods study.

Schuster, Lara / Führes, Hannah / Wandke, Svenja / Thomas, Mareike / Scholl, Isabelle

Psycho-oncology

2023 Volume 33, Issue 1, Page(s) e6257

Abstract: Objective: During the Covid-19 pandemic, there has been a substantial uptake of telemental health interventions. Consequently, the objective of this study was to assess psycho-oncologists' attitudes toward and experiences with video consultations (VC) ... ...

Abstract	Objective: During the Covid-19 pandemic, there has been a substantial uptake of telemental health interventions. Consequently, the objective of this study was to assess psycho-oncologists' attitudes toward and experiences with video consultations (VC) since the beginning of the Covid-19 pandemic. Additionally, we sought to investigate psycho-oncologists' perspectives on the benefits and drawbacks of VC and its' potential implementation beyond the pandemic. Methods: We used a multi-methods study design. First, semi-structured interviews with psycho-oncologists (N = 6) were conducted to inform the development of a cross-sectional online survey, which represented the quantitative part of our study. We invited psycho-oncologists, working in different settings, from all over Germany to participate. Results: Data of N = 217 participants (88% female, 49% over 10 years work experience) of the online survey was analyzed. Psycho-oncologists' acceptance toward VC was average to high. In their daily practice, they preferred in-person consultations. Improved access to care and enhanced flexibility were seen as main advantages. The most significant disadvantages included technical issues, privacy concerns at home, loss of non-verbal cues and absence of physical presence for emotional support. Nevertheless, on average, psycho-oncologists wanted to continue seeing approximately 25% of their patients via VC in the future. Conclusions: Given the average to high acceptance of VC among psycho-oncologists and their desire to continue using VC flexibly even after the pandemic, it may be beneficial to implement VC into future psycho-oncology services. Still, future research should focus on the patients' perspective and the effectiveness of VC in psycho-oncology services.
MeSH term(s)	Humans ; Female ; Male ; COVID-19 ; Pandemics ; Cross-Sectional Studies ; Oncologists/psychology ; Referral and Consultation ; Telemedicine/methods
Language	English
Publishing date	2023-12-11
Publishing country	England
Document type	Journal Article
ZDB-ID	1118536-3
ISSN	1099-1611 ; 1057-9249
ISSN (online)	1099-1611
ISSN	1057-9249
DOI	10.1002/pon.6257
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Article: Premorbid Psychological Factors Associated with Long-Term Postoperative Headache after Microsurgery in Vestibular Schwannoma-A Retrospective Pilot Study.

Thomas, Mareike / Rampp, Stefan / Scheer, Maximilian / Strauss, Christian / Prell, Julian / Schönfeld, Robby / Leplow, Bernd

Brain sciences

2023 Volume 13, Issue 8

Abstract: Associations between premorbid psychological factors and postoperative headache (POH) after microsurgical treatment via the retrosigmoid approach for vestibular schwannoma (VS) were investigated in this retrospective single-center study. A total of 101 ... ...

Abstract	Associations between premorbid psychological factors and postoperative headache (POH) after microsurgical treatment via the retrosigmoid approach for vestibular schwannoma (VS) were investigated in this retrospective single-center study. A total of 101 VS patients completed the Rostock headache questionnaire (RoKoKo), the hospital and anxiety scale (HADS-D), and the screening for somatoform disorders (SOMS-2), all of which were used as short self-assessed questionnaires. Fifty-four patients with POH were compared with 47 non-POH patients in terms of premorbid psychological factors, somatization tendencies, and psychological burden using the chi
Language	English
Publishing date	2023-08-07
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2651993-8
ISSN	2076-3425
ISSN	2076-3425
DOI	10.3390/brainsci13081171
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Article ; Online: Characteristics of behavioural addiction in Parkinson's disease patients with self-reported impulse control disorder and controls matched for levodopa equivalent dose: a matched case-control study.

Leplow, Bernd / Renftle, Daniela / Thomas, Mareike / Michaelis, Katja / Solbrig, Susanne / Maetzler, Walter / Berg, Daniela / Liepelt-Scarfone, Inga

Journal of neural transmission (Vienna, Austria : 1996)

2023 Volume 130, Issue 2, Page(s) 125–133

Abstract: Impulse control disorders (ICD) in Parkinson's disease (PD) frequently occur, not always as a direct consequence of dopaminergic medication. This study investigated premorbid personality traits and behavioural characteristics in non-demented PD patients ... ...

Abstract	Impulse control disorders (ICD) in Parkinson's disease (PD) frequently occur, not always as a direct consequence of dopaminergic medication. This study investigated premorbid personality traits and behavioural characteristics in non-demented PD patients with self-reported symptoms of ICD (PD-srICD). From a total of 200 non-demented PD patients who filled out questionnaires assessing symptoms and severity of ICD, those were classified as PD-srICD (n = 32) who reported current occurrence of at least one compulsive behaviour (gambling, sexual behaviour, buying behaviour, or eating). As a control group, 32 patients with no self-reported ICD symptoms were matched for levodopa equivalent daily dose. The demographic, clinical, and premorbid personality profiles were compared between both groups. Frequency of psychological characteristics indicating substance use disorder was evaluated in patients with PD-srICD. Patients with PD-srICD were more frequently male, younger at examination, had earlier PD onset, more depression, higher non-motor burden, less quality of life (p < 0.05, respectively), and more frequently reported premorbid sensation seeking/novelty orientation (p = 0.03) and joyful experience of stress (p = 0.04) than patients in the control group. Of patients with PD-srICD, 90.6% reported at least one behavioural characteristic of substance use disorder, most frequently positive expectations following ICD behaviour and illusional beliefs about its behavioural control. Signs of addiction were common among patients with PD-srICD. Therefore, the profile of psychological characteristics in patients with PD-srICD resembled that of patients with substance use disorder. It can be concluded that dopamine replacement therapy (DRT) alone does not account for PD-srICD and that thorough psychological diagnostics are recommended.
MeSH term(s)	Humans ; Male ; Parkinson Disease/complications ; Parkinson Disease/drug therapy ; Parkinson Disease/epidemiology ; Levodopa/therapeutic use ; Case-Control Studies ; Quality of Life ; Disruptive, Impulse Control, and Conduct Disorders/etiology ; Behavior, Addictive
Chemical Substances	Levodopa (46627O600J)
Language	English
Publishing date	2023-01-20
Publishing country	Austria
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	184163-4
ISSN	1435-1463 ; 0300-9564
ISSN (online)	1435-1463
ISSN	0300-9564
DOI	10.1007/s00702-023-02588-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Mehrfachausbildungen: Wer sie macht und was sie bringen

Thomas, Mareike

Befunde der LifE-Studie

2013

Abstract: â€‹Der Weg nach der Schule fÃ¼hrte klassisch in eine Ausbildung und anschlieÃŸend in die ErwerbstÃ¤tigkeit. Im Fokus dieser Untersuchung stehen hingegen Wege mit mehr als einer Ausbildung. Mareike Thomas fragt, welche Personen Mehrfachausbildungen ... ...

Author's details	Mareike Thomas
Abstract	â€‹Der Weg nach der Schule fÃ¼hrte klassisch in eine Ausbildung und anschlieÃŸend in die ErwerbstÃ¤tigkeit. Im Fokus dieser Untersuchung stehen hingegen Wege mit mehr als einer Ausbildung. Mareike Thomas fragt, welche Personen Mehrfachausbildungen beginnen und was sie Ã¼berhaupt bringen. Die Analyse basiert auf einer in Deutschland einzigartig angelegten LÃ¤ngsschnittstudie: die LifE-Studie (seit 1979). Sie ermÃ¶glicht erstmalig, Effekte von PersÃ¶nlichkeitseigenschaften auf Ausbildungswege zu untersuchen. ZusÃ¤tzlich wird das Augenmerk auf die soziale Herkunft gerichtet. Die Untersuchung gibt
Keywords	Social sciences ; Politik # Soziologie
Language	German
Size	Online-Ressource (XXIV, 267 S. 28 Abb), Ill.
Publisher	Springer VS
Publishing place	Wiesbaden
Document type	Book ; Online
ISBN	9783658039622 ; 3658039620
DOI	10.1007/978-3-658-03962-2
Database	Former special subject collection: coastal and deep sea fishing

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Book ; Online: Mehrfachausbildungen: Wer sie macht und was sie bringen

Thomas, Mareike

Befunde der LifE-Studie

2013

Author's details	von Mareike Thomas
Abstract	â€‹Der Weg nach der Schule fÃ¼hrte klassisch in eine Ausbildung und anschlieÃŸend in die ErwerbstÃ¤tigkeit. Im Fokus dieser Untersuchung stehen hingegen Wege mit mehr als einer Ausbildung. Mareike Thomas fragt, welche Personen Mehrfachausbildungen beginnen und was sie Ã¼berhaupt bringen. Die Analyse basiert auf einer in Deutschland einzigartig angelegten LÃ¤ngsschnittstudie: die LifE-Studie (seit 1979). Sie ermÃ¶glicht erstmalig, Effekte von PersÃ¶nlichkeitseigenschaften auf Ausbildungswege zu untersuchen. ZusÃ¤tzlich wird das Augenmerk auf die soziale Herkunft gerichtet. Die Untersuchung gibt
Keywords	Social sciences ; Politik Soziologie
Language	German
Size	Online-Ressource
Publisher	Springer Fachmedien Wiesbaden
Publishing place	Wiesbaden
Document type	Book ; Online
Note	Description based upon print version of record
ISBN	9783658039622 ; 3658039620
DOI	10.1007/978-3-658-03962-2
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article: Premorbid psychological factors associated with long-term postoperative headache after microsurgery in vestibular schwannoma - A retrospective pilot study

Thomas, Mareike / Rampp, Stefan / Scheer, Maximilian / Strauss, Christian / Prell, Julian / Schönfeld, Robby / Leplow, Bernd

Brain Sciences

2023 Volume 13, Issue 8, Page(s) No

Title translation	Prämorbide psychologische Faktoren im Zusammenhang mit langfristigen postoperativen Kopfschmerzen nach mikrochirurgischen Eingriffen bei vestibulären Schwannomen - Eine retrospektive Pilotstudie (DeepL)
Abstract	Associations between premorbid psychological factors and postoperative headache (POH) after microsurgical treatment via the retrosigmoid approach for vestibular schwannoma (VS) were investigated in this retrospective single-center study. A total of 101 VS patients completed the Rostock headache questionnaire (RoKoKo), the hospital and anxiety scale (HADS-D), and the screening for somatoform disorders (SOMS-2), all of which were used as short self-assessed questionnaires. Fifty-four patients with POH were compared with 47 non-POH patients in terms of premorbid psychological factors, somatization tendencies, and psychological burden using the chi2-test and Mann-Whitney U-test. Regression analyses were conducted to assess the weighted contribution of psychological and procedural factors to POH. In individuals with POH, mental ailments, preexisting headaches, premorbid chronic pain syndromes, and higher somatization tendencies were found to be significantly more common. POH was predicted by the number of premorbid psychosomatic symptoms, preexisting mental ailments, and premorbid chronic pain syndromes. Depression and anxiety were predicted by low emotional stability. Additionally, the number of premorbid psychosomatic symptoms predicted depression, anxiety, and overall psychological burden. It was observed that the reported symptoms of headache might fit into the classification of chronic postsurgical pain (CPSP) rather than being classified as secondary headaches after craniotomy. Premorbid psychological factors were found to play an important role in the emergence of POH in VS, particularly after microsurgery via the retrosigmoid approach. Therefore, it is suggested that psychological screening be incorporated into the treatment process.
Keywords	Chirurgie ; Chronic Pain ; Chronischer Schmerz ; Emotional Stability ; Emotionale Stabilität ; Folgeschäden ; Headache ; Kopfschmerz ; Mental Disorders ; Postoperative Komplikationen ; Postsurgical Complications ; Premorbidity ; Prämorbidität ; Psychische Störungen ; Risikofaktoren ; Risk Factors ; Sequelae ; Somatisierung ; Somatization ; Surgery
Language	English
Document type	Article
DOI	10.3390/brainsci13081171
Database	PSYNDEX

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Book ; Online ; Thesis: Psychologische Einflussfaktoren auf den posttherapeutischen Kopfschmerz und die interventionsbezogene Lebensqualität nach Behandlung eines Vestibularisschwannoms

Thomas, Mareike [Verfasser] / Prell, Julian Gutachter] / [Leplow, Bernd [Gutachter] / Rahne, Torsten [Gutachter] / Goebel, Simone [Gutachter]

2022

Author's details	Mareike Thomas ; Gutachter: Julian Prell, Bernd Leplow, Torsten Rahne, Simone Goebel
Keywords	Medizin, Gesundheit ; Medicine, Health
Subject code	sg610
Language	German
Publisher	Universitäts- und Landesbibliothek Sachsen-Anhalt
Publishing place	Halle (Saale)
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

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Article: Characteristics of behavioural addiction in Parkinson's disease patients with self-reported impulse control disorder and controls matched for levodopa equivalent dose

Leplow, Bernd / Renftle, Daniela / Thomas, Mareike / Michaelis, Katja / Solbrig, Susanne / Maetzler, Walter / Berg, Daniela / Liepelt-Scarfone, Inga

Journal of Neural Transmission

A matched case-control study

2023 Volume 130, Page(s) 125–133

Title translation	Merkmale der Verhaltenssucht bei Parkinson-Patienten mit selbstberichteter Impulskontrollstörung und Kontrollen, die auf die Levodopa-Äquivalentdosis abgestimmt sind: eine abgestimmte Fall-Kontroll-Studie. (DeepL)
Abstract	Impulse control disorders (ICD) in Parkinson's disease (PD) frequently occur, not always as a direct consequence of dopaminergic medication. This study investigated premorbid personality traits and behavioural characteristics in non-demented PD patients with self-reported symptoms of ICD (PD-srICD). From a total of 200 non-demented PD patients who filled out questionnaires assessing symptoms and severity of ICD, those were classified as PD-srICD (n = 32) who reported current occurrence of at least one compulsive behaviour (gambling, sexual behaviour, buying behaviour, or eating). As a control group, 32 patients with no self-reported ICD symptoms were matched for levodopa equivalent daily dose. The demographic, clinical, and premorbid personality profiles were compared between both groups. Frequency of psychological characteristics indicating substance use disorder was evaluated in patients with PD-srICD. Patients with PD-srICD were more frequently male, younger at examination, had earlier PD onset, more depression, higher non-motor burden, less quality of life (p < 0.05, respectively), and more frequently reported premorbid sensation seeking/novelty orientation (p = 0.03) and joyful experience of stress (p = 0.04) than patients in the control group. Of patients with PD-srICD, 90.6% reported at least one behavioural characteristic of substance use disorder, most frequently positive expectations following ICD behaviour and illusional beliefs about its behavioural control. Signs of addiction were common among patients with PD-srICD. Therefore, the profile of psychological characteristics in patients with PD-srICD resembled that of patients with substance use disorder. It can be concluded that dopamine replacement therapy (DRT) alone does not account for PD-srICD and that thorough psychological diagnostics are recommended.
Keywords	Addiction ; Client Characteristics ; Impulse Control Disorders ; Impulskontrollstörung ; L-Dopa ; Levodopa ; Merkmale von Klientinnen und Klienten ; Nonsubstance Related Addictions ; Parkinson's Disease ; Parkinson-Krankheit ; Personality Traits ; Persönlichkeitsmerkmale ; Substanzungebundene Sucht ; Sucht
Language	English
Document type	Article
ZDB-ID	184163-4
ISSN	1435-1463 ; 0300-9564
ISSN (online)	1435-1463
ISSN	0300-9564
DOI	10.1007/s00702-023-02588-8
Database	PSYNDEX

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Article ; Online: Changes in brain function during negative emotion processing in the long-term course of depression.

The British journal of psychiatry : the journal of mental science

2022 Volume 221, Issue 2, Page(s) 476–484

Abstract: Background: Relapses in major depression are frequent and are associated with a high burden of disease. Although short-term studies suggest a normalisation of depression-associated brain functional alterations directly after treatment, long-term ... ...

Abstract	Background: Relapses in major depression are frequent and are associated with a high burden of disease. Although short-term studies suggest a normalisation of depression-associated brain functional alterations directly after treatment, long-term investigations are sparse. Aims: To examine brain function during negative emotion processing in association with course of illness over a 2-year span. Method: In this prospective case-control study, 72 in-patients with current depression and 42 healthy controls were investigated during a negative emotional face processing paradigm, at baseline and after 2 years. According to their course of illness during the study interval, patients were divided into subgroups ( Results: A significant relapse × time interaction emerged within the amygdala ( Conclusions: This study reveals course of illness-associated activity changes in emotion processing areas. Patients in full remission show a normalisation of their baseline hypo-responsiveness to the activation level of healthy controls after 2 years. Brain function during emotion processing could further serve as a potential predictive marker for future relapse.
MeSH term(s)	Brain/diagnostic imaging ; Brain Mapping ; Case-Control Studies ; Depression ; Depressive Disorder, Major/psychology ; Emotions/physiology ; Humans ; Magnetic Resonance Imaging
Language	English
Publishing date	2022-01-23
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218103-4
ISSN	1472-1465 ; 0007-1250
ISSN (online)	1472-1465
ISSN	0007-1250
DOI	10.1192/bjp.2021.223
Database	MEDical Literature Analysis and Retrieval System OnLINE

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