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Book: Good beer guide Germany

Thomas, Steve

[the completely independent guide to more than 1250 German breweries, 7500 German beers plus great places to try them]

2006

Author's details	Steve Thomas
Keywords	Beer ; Breweries ; Bars (Drinking establishments) ; Germany ; Deutschland ; Bier
Subject	Gerstensaft
Subject code	641.230943
Language	English
Size	573 S. : Ill., graph. Darst., 21cm
Publisher	CAMRA
Publishing place	St. Albans
Publishing country	Great Britain
Document type	Book
Note	Includes some German
HBZ-ID	HT014722487
ISBN	1-85249-219-8 ; 978-1-85249-219-9
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

In stock of ZB MED Bonn / Germany

Shelf mark	Loan status	Location
068/894	available for loan (reading room)	Freihandmagazin (U1)

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Article ; Online: Lifecycle evaluation of medical devices: supporting or jeopardizing patient outcomes? A comparative analysis of evaluation models.

Harkin, Kathleen R / Sorensen, Jan / Thomas, Steve

International journal of technology assessment in health care

2024 Volume 40, Issue 1, Page(s) e2

Abstract: Objectives: Lack of evidence regarding safety and effectiveness at market entry is driving the need to consider adopting a lifecycle approach to evaluating medical devices, but it is unclear what lifecycle evaluation means. This research sought to ... ...

Abstract	Objectives: Lack of evidence regarding safety and effectiveness at market entry is driving the need to consider adopting a lifecycle approach to evaluating medical devices, but it is unclear what lifecycle evaluation means. This research sought to explore the tacit meanings of "lifecycle" and "lifecycle evaluation" as embodied within evaluation models/frameworks used for medical devices. Methods: Drawing on qualitative evidence synthesis methods and using an inductive approach, novel methods were developed to identify, appraise, analyze, and synthesize lifecycle evaluation models used for medical devices. Data was extracted (including purpose; audience; characterization; outputs; timing; and type of model) from key texts for coding, categorization, and comparison, exploring embodied meaning across four broad perspectives. Results: Fifty-two models were included in the synthesis. They demonstrated significant heterogeneity of meaning, form, scope, timing, and purpose. The "lifecycle" may represent a single stage, a series of stages, a cycle of innovation, or a system. "Lifecycle evaluation" focuses on the overarching goal of the stakeholder group, and may use a single or repeated evaluation to inform decision-making regarding the adoption of health technologies (Healthcare), resource allocation (Policymaking), investment in new product development or marketing (Trade and Industry), or market regulation (Regulation). The adoption of a lifecycle approach by regulators has resulted in the deferral of evidence generation to the post-market phase. Conclusions: Using a "lifecycle evaluation" approach to inform reimbursement decision-making must not be allowed to further jeopardize evidence generation and patient safety by accepting inadequate evidence of safety and effectiveness for reimbursement decisions.
MeSH term(s)	Policy Making ; Equipment and Supplies/standards
Language	English
Publishing date	2024-01-05
Publishing country	England
Document type	Journal Article
ZDB-ID	632573-7
ISSN	1471-6348 ; 0266-4623
ISSN (online)	1471-6348
ISSN	0266-4623
DOI	10.1017/S026646232300274X
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Book ; Conference proceedings: Multiscale cancer modeling

Deisböck, Thomas S.

[First Transatlantic Workshop on Multiscale Cancer Modeling in Brussels, Belgium ... October 23 - 24, 2008]

(Chapman & Hall CRC mathematical and computational biology series ; 34)

2011

Event/congress	Transatlantic Workshop on Multiscale Cancer Modeling (1, 2008, Brüssel)
Author's details	ed. by Thomas S. Deisboeck
Series title	Chapman & Hall CRC mathematical and computational biology series ; 34
Collection
Keywords	Neoplasms / physiopathology ; Neoplasms / pathology ; Neoplastic Processes ; Models, Biological
Language	English
Size	XXIV, 460 S., [8 Bl.] : Ill., graph. Darst.
Publisher	CRC Press
Publishing place	Boca Raton u.a.
Publishing country	United States
Document type	Book ; Conference proceedings
HBZ-ID	HT016234148
ISBN	978-1-4398-1440-6 ; 1-4398-1440-6
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2011 A 437	order for loan	Magazin

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Article ; Online: Alpibectir: Early Qualitative and Quantitative Metabolic Profiling from a First Time in Human Study by Combining

Weston, Daniel J / Thomas, Steve / Boyle, Gary W / Pieren, Michel

Drug metabolism and disposition: the biological fate of chemicals

2024

Abstract: Alpibectir (also known as BVL-GSK098 and GSK3729098) is a new chemical entity with a novel mechanism for the treatment of tuberculosis. The disposition of alpibectir was determined in subjects from a first in human trial after a single oral dose of 40 mg, ...

Abstract	Alpibectir (also known as BVL-GSK098 and GSK3729098) is a new chemical entity with a novel mechanism for the treatment of tuberculosis. The disposition of alpibectir was determined in subjects from a first in human trial after a single oral dose of 40 mg, and after 7 days repeat dosing at 30 mg. Here we present a combined approach of UPLC-HRMS,
Language	English
Publishing date	2024-05-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	186795-7
ISSN	1521-009X ; 0090-9556
ISSN (online)	1521-009X
ISSN	0090-9556
DOI	10.1124/dmd.124.001562
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Article: Is it the end of the line for Light Water Reactor technology or can China and Russia save the day?

Thomas, Steve

Energy policy. 2019 Feb., v. 125

2019

Abstract: In the late 1990s, a new generation of reactor designs evolved from existing designs was touted as solving the economic problems that led to the collapse of reactor ordering after the Chernobyl disaster. It was claimed these designs would be cheap and ... ...

Abstract	In the late 1990s, a new generation of reactor designs evolved from existing designs was touted as solving the economic problems that led to the collapse of reactor ordering after the Chernobyl disaster. It was claimed these designs would be cheap and easy to build because they would be simpler and use passive safety, modular construction and standardisation. The US and UK governments were convinced by this and launched reactor construction programmes. However, 20 years on, the claims have proved false and the US and UK programmes are in disarray. The last hope for the nuclear industry appears to be that Chinese and Russian reactor vendors, with powerful support from their governments, will take over, providing reactors that are cheap but meet the safety standards required in Europe and North America. However, these vendors and their designs are largely unproven in open markets. There is also little evidence that their reactors will be cheap, there are concerns about quality and safety culture and there are national security concerns that may deter customers. New technologies, such as radical new ones, Generation IV, and Small Modular Reactors are unproven and, at best, a long way from commercial deployment
Keywords	consumers (people) ; markets ; safety standards ; technology ; China ; Russia ; United Kingdom ; United States
Language	English
Dates of publication	2019-02
Size	p. 216-226.
Publishing place	Elsevier Ltd
Document type	Article
ISSN	0301-4215
DOI	10.1016/j.enpol.2018.10.062
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Understanding the legacies of shocks on health system performance: Exploring Ireland's management of recent crises and its implications for policy.

Farsaci, Liz / Fleming, Padraic / Almirall-Sanchez, Arianna / O'Donoghue, Catherine / Thomas, Steve

Health policy (Amsterdam, Netherlands)

2024 Volume 143, Page(s) 105063

Abstract: This paper contrasts the Irish experience of the 2008 economic crisis and the Covid-19 pandemic, and the health system responses to these shocks, from the perspective of health system leaders working across both time periods. Based on semi-structured ... ...

Abstract	This paper contrasts the Irish experience of the 2008 economic crisis and the Covid-19 pandemic, and the health system responses to these shocks, from the perspective of health system leaders working across both time periods. Based on semi-structured interviews with seven senior national and international officials, the research presented here forms the qualitative component of RESTORE, a five-year research project examining health system resilience and reform, funded through the Health Research Board's Research Leader Award in Ireland. Findings indicate that the financial crisis deeply impacted the Irish health system in relation to infrastructure and capacity, service delivery and workforce. Due to these legacy issues, Ireland's health system was in a relatively weak position when faced with the Covid-19 pandemic but the system proved adaptive and innovative during this time. Furthermore, the pandemic proved to be a catalyst for positive change, providing opportunities for long-term reform, alongside an immediate response to the crisis. This was facilitated by increased funding, a devolution in decision-making structures and a political commitment to the health system. Exploring lessons from the Irish response to these crises provides a case study for developing appropriate policy responses around financing and resource allocation, fostering support for healthcare among political leaders and policy makers, and preparing for future shocks. Furthermore, examining these experiences facilitates understanding around the impact of each crisis on the health system, exploring options for addressing legacy issues and considering practical steps to improve health system performance.
MeSH term(s)	Humans ; Ireland ; Pandemics ; Delivery of Health Care ; Policy ; COVID-19
Language	English
Publishing date	2024-04-04
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	605805-x
ISSN	1872-6054 ; 0168-8510
ISSN (online)	1872-6054
ISSN	0168-8510
DOI	10.1016/j.healthpol.2024.105063
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Article: Russia's Nuclear Export Programme

Thomas, Steve

Energy policy. 2018 Oct., v. 121

2018

Abstract: Since 2009, after a largely dormant period since the Chernobyl disaster, Russia, through Rosatom, has come to dominate the world reactor export market with a new design it claims achieves equivalent safety standards to the latest designs from other ... ...

Abstract	Since 2009, after a largely dormant period since the Chernobyl disaster, Russia, through Rosatom, has come to dominate the world reactor export market with a new design it claims achieves equivalent safety standards to the latest designs from other vendors. In this paper we examine the structure of the Russian nuclear industry and the technology offered and the political backing that has allowed it to achieve this dominance. We review construction and operation experience with new orders since Chernobyl. We then examine the status of the large number of orders Rosatom has won, the estimates of construction cost and how they compare with those of its competitors. We then examine whether Russia and Rosatom will have the financial and supply chain capability to fulfil more than a small proportion of its order book. Finally, we draw lessons for countries that have placed or are considering placing orders for Russian reactors.
Keywords	exports ; markets ; nuclear power industry ; physiological transport ; politics ; safety standards ; supply chain ; Russia
Language	English
Dates of publication	2018-10
Size	p. 236-247.
Publishing place	Elsevier Ltd
Document type	Article
ISSN	0301-4215
DOI	10.1016/j.enpol.2018.06.036
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Assessing resilience of a health system is difficult but necessary to prepare for the next crisis.

Sagan, Anna / Thomas, Steve / Webb, Erin / McKee, Martin

BMJ (Clinical research ed.)

2023 Volume 382, Page(s) e073721

MeSH term(s)	Humans ; Delivery of Health Care ; Government Programs
Language	English
Publishing date	2023-07-04
Publishing country	England
Document type	Journal Article
ZDB-ID	1362901-3
ISSN	1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
ISSN (online)	1756-1833
ISSN	0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
DOI	10.1136/bmj-2022-073721
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Article: China's nuclear export drive: Trojan Horse or Marshall Plan?

Thomas, Steve

Energy Policy. 2017 Feb., v. 101

2017

Abstract: China's civil nuclear industry expanded strongly from 2008 onwards and nearly half of reactor construction starts worldwide since then are accounted for by the Chinese home market. Increasingly China is turning its attention to the export market using ... ...

Abstract	China's civil nuclear industry expanded strongly from 2008 onwards and nearly half of reactor construction starts worldwide since then are accounted for by the Chinese home market. Increasingly China is turning its attention to the export market using its own designs, which it claims emulate the safety standards of the latest designs of the established nuclear reactor vendors. Its export efforts would be greatly strengthened if it were to win an order from an established user of nuclear power and its best opportunity appears to be the UK where it is at the early stages of negotiating the construction of nuclear reactors. The financial collapse of the French nuclear company, Areva, gives it the opportunity to take a stake in the rescued companies giving it access to important fuel cycle technologies and perhaps the large French reactor service market. Its other export prospects in Europe are in Romania and Turkey. There are a number of issues European governments need to examine before committing to allow in Chinese nuclear companies. These include national security concerns about dependence on China for key infrastructure, issues of quality control and regulatory competence and the lack of construction experience with China's modern reactor designs.
Keywords	business enterprises ; exports ; fuels ; industry ; infrastructure ; markets ; nuclear power ; physiological transport ; quality control ; safety standards ; China ; Romania ; Turkey (country) ; United Kingdom
Language	English
Dates of publication	2017-02
Size	p. 683-691.
Publishing place	Elsevier Ltd
Document type	Article
ISSN	0301-4215
DOI	10.1016/j.enpol.2016.09.038
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Implications for health system reform, workforce recovery and rebuilding in the context of the Great Recession and COVID-19: a case study of workforce trends in Ireland 2008-2021.

Fleming, Padraic / Thomas, Steve / Williams, Des / Kennedy, Jack / Burke, Sara

Human resources for health

2022 Volume 20, Issue 1, Page(s) 48

Abstract: Background: Workforce is a fundamental health systems building block, with unprecedented measures taken to meet extra demand and facilitate surge capacity during the COVID-19 pandemic, following a prolonged period of austerity. This case study examines ... ...

Abstract	Background: Workforce is a fundamental health systems building block, with unprecedented measures taken to meet extra demand and facilitate surge capacity during the COVID-19 pandemic, following a prolonged period of austerity. This case study examines trends in Ireland's publicly funded health service workforce, from the global financial crisis, through the Recovery period and into the COVID-19 pandemic, to understand resource allocation across community and acute settings. Specifically, this paper aims to uncover whether skill-mix and staff capacity are aligned with policy intent and the broader reform agenda to achieve universal access to integrated healthcare, in part, by shifting free care into primary and community settings. Methods: Secondary analysis of anonymised aggregated national human resources data was conducted over a period of almost 14 years, from December 31st 2008 to August 31st 2021. Comparative analysis was conducted, by professional cadre, across three keys periods: 'Recession period' December 31st 2008-December 31st 2014; 'Recovery period' December 31st 2014-December 31st 2019; and the 'COVID-19 period' December 31st 2019-August 31st 2021. Results: During the Recession period there was an overall decrease of 8.1% (n = 9333) between December 31st 2008 and December 31st 2014, while the Recovery period saw the overall staff levels rebound and increase by 15.2% (n = 16,789) between December 31st 2014 and December 31st 2019. These figures continued to grow, at an accelerated rate during the most recent COVID-19 period, increasing by a further 8.9% (n = 10,716) in under 2 years. However, a notable shift occurred in 2013, when the number of staff in acute services surpassed those employed in community services (n = 50,038 and 49,857, respectively). This gap accelerated during the Recovery and COVID-19 phase. By August 2021, there were 13,645 more whole-time equivalents in acute settings compared to community, a complete reverse of the 2008 situation. This was consistent across all cadres. Workforce absence trends indicate short-term spikes resulting from shocks while COVID-19 redeployment disproportionately impacted negatively on primary care and community services. Conclusions: This paper clearly demonstrates the prioritisation of staff recruitment within acute services-increasing needed capacity, without the same commitment to support government policy to shift care into primary and community settings. Concerted action including the permanent redistribution of personnel is required to ensure progressive and sustainable responses are learned from recent shocks.
MeSH term(s)	COVID-19/epidemiology ; Government Programs ; Humans ; Ireland ; Pandemics ; Workforce
Language	English
Publishing date	2022-05-26
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2126923-3
ISSN	1478-4491 ; 1478-4491
ISSN (online)	1478-4491
ISSN	1478-4491
DOI	10.1186/s12960-022-00747-8
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