LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 106

Search options

  1. Article: Rural Identity and LGBT Public Opinion in the United States.

    Thompson, Jack

    Public opinion quarterly

    2023  Volume 87, Issue 4, Page(s) 956–977

    Abstract: Opposition to LGBT rights remains a contemporary fixture within the United States in spite of increasingly liberalizing attitudes toward LGBT individuals. In this paper, I argue that a potentially overlooked factor driving this opposition is rural ... ...

    Abstract Opposition to LGBT rights remains a contemporary fixture within the United States in spite of increasingly liberalizing attitudes toward LGBT individuals. In this paper, I argue that a potentially overlooked factor driving this opposition is rural identity-or an individual's psychological attachment to a rural area. Using data from the 2020 ANES, I find that rural identity predicts less favorable estimations of LGBT individuals. Rural identifiers are also less likely to support pro-LGBT policy measures than nonrural identifiers. Nevertheless, I find the magnitude of the effects of rural identity on anti-LGBT views to be surprisingly small. It is also the case that, on average, rural identifiers exhibit net-positive estimations of LGBT individuals and are broadly supportive of LGBT rights, suggesting that elected officials enacting anti-LGBT legislation in rural areas of the United States are potentially out of step with the preferences of their electorate. These findings also have implications for what it means to hold a rural identity beyond a generalized animosity toward urban areas, and for understanding urban-rural divergences in US public opinion on issues such as LGBT rights.
    Language English
    Publishing date 2023-11-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2009642-2
    ISSN 1537-5331 ; 0033-362X
    ISSN (online) 1537-5331
    ISSN 0033-362X
    DOI 10.1093/poq/nfad045
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Apparent Half-Lives of Chlorinated-Perfluorooctane Sulfonate and Perfluorooctane Sulfonate Isomers in Aviation Firefighters.

    Nilsson, Sandra / Thompson, Jack / Mueller, Jochen F / Bräunig, Jennifer

    Environmental science & technology

    2022  Volume 56, Issue 23, Page(s) 17052–17060

    Abstract: Elevated levels of perfluorooctane sulfonate (PFOS) and elevated detection frequency of chloro-substituted PFOS have been reported in Australian firefighters with historical exposure to aqueous-film forming foam (AFFF). The aim of this study is to ... ...

    Abstract Elevated levels of perfluorooctane sulfonate (PFOS) and elevated detection frequency of chloro-substituted PFOS have been reported in Australian firefighters with historical exposure to aqueous-film forming foam (AFFF). The aim of this study is to estimate the apparent half-lives of Cl-PFOS and PFOS isomers in firefighters following the end of exposure to 3M-AFFF. Paired serum samples from 120 firefighters, collected approximately five years apart, were analyzed for 8-Cl-PFOS (8-chloroperfluoro-1-octanesulfonic acid) and PFOS isomers via targeted LC-MS/MS. Apparent half-life was estimated by assuming a first order-elimination model. Cl-PFOS was detected in 93% of all initial serum samples (<LOQ-1.09 ng/mL). The average half-life of Cl-PFOS among the firefighters was 5.0 years. Branched PFOS isomers made up 55% of the total isomer concentration at the initial sampling timepoint. Five years later, the proportion of branched PFOS isomers was greater (65%). The longest average half-life (11.5 years) was estimated for "1m-PFOS". Other isomers had average half-lives ranging from 4.0 to 7.5 years. Marked differences in half-lives between PFOS isomers suggest that the elimination rate of "total PFOS" (sum of all PFOS isomers) is non-linear. This is the first study to report the serum concentrations and apparent half-life of Cl-PFOS in humans.<br />
    Language English
    Publishing date 2022-11-11
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.2c04637
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Pharmacogenomic Considerations for Anticoagulant Prescription in Patients with Hereditary Haemorrhagic Telangiectasia.

    McCarley, Sarah C / Murphy, Daniel A / Thompson, Jack / Shovlin, Claire L

    Journal of clinical medicine

    2023  Volume 12, Issue 24

    Abstract: Hereditary haemorrhagic telangiectasia (HHT) is a vascular dysplasia that commonly results in bleeding but with frequent indications for therapeutic anticoagulation. Our aims were to advance the understanding of drug-specific intolerance and evaluate if ... ...

    Abstract Hereditary haemorrhagic telangiectasia (HHT) is a vascular dysplasia that commonly results in bleeding but with frequent indications for therapeutic anticoagulation. Our aims were to advance the understanding of drug-specific intolerance and evaluate if there was an indication for pharmacogenomic testing. Genes encoding proteins involved in the absorption, distribution, metabolism, and excretion of warfarin, heparin, and direct oral anticoagulants (DOACs) apixaban, rivaroxaban, edoxaban, and dabigatran were identified and examined. Linkage disequilibrium with HHT genes was excluded, before variants within these genes were examined following whole genome sequencing of general and HHT populations. The 44 genes identified included 5/17 actionable pharmacogenes with guidelines. The 76,156 participants in the Genome Aggregation Database v3.1.2 had 28,446 variants, including 9668 missense substitutions and 1076 predicted loss-of-function (frameshift, nonsense, and consensus splice site) variants, i.e., approximately 1 in 7.9 individuals had a missense substitution, and 1 in 71 had a loss-of-function variant. Focusing on the 17 genes relevant to usually preferred DOACs, similar variant profiles were identified in HHT patients. With HHT patients at particular risk of haemorrhage when undergoing anticoagulant treatment, we explore how pre-emptive pharmacogenomic testing, alongside HHT gene testing, may prove beneficial in reducing the risk of bleeding and conclude that HHT patients are well placed to be at the vanguard of personalised prescribing.
    Language English
    Publishing date 2023-12-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12247710
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Book: The psychobiology of emotions

    Thompson, Jack George

    (Emotions, personality, and psychotherapy)

    1988  

    Author's details Jack George Thompson
    Series title Emotions, personality, and psychotherapy
    Keywords Emotions / physiology ; Psychophysiology ; Gefühl ; Psychobiologie
    Subject Biologische Psychologie ; Affektleben ; Emotion ; Emotionalität ; Fühlen ; Gemütsbewegung ; Gefühlsleben ; Gefühle
    Language English
    Size XIII, 404 S. : Ill., graph. Darst.
    Publisher Plenum Pr
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT003228636
    ISBN 0-306-42843-1 ; 978-0-306-42843-2
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

  5. Article ; Online: Correlates of support for international vaccine solidarity during the COVID-19 pandemic: Cross-sectional survey evidence from Germany.

    Stoeckel, Florian / Thompson, Jack / Szewach, Paula / Stöckli, Sabrina / Barnfield, Matthew / Phillips, Joseph B / Lyons, Benjamin / Mérola, Vittorio / Reifler, Jason

    PloS one

    2023  Volume 18, Issue 6, Page(s) e0287257

    Abstract: During the COVID-19 pandemic, many residents of high-income countries (HICs) were eligible for COVID-19 vaccine boosters, while many residents of lower-income countries (LICs) had not yet received a first dose. HICs made some efforts to contribute to ... ...

    Abstract During the COVID-19 pandemic, many residents of high-income countries (HICs) were eligible for COVID-19 vaccine boosters, while many residents of lower-income countries (LICs) had not yet received a first dose. HICs made some efforts to contribute to COVID-19 vaccination efforts in LICs, but these efforts were limited in scale. A new literature discusses the normative importance of an international redistribution of vaccines. Our analysis contributes an empirical perspective on the willingness of citizens in a HIC to contribute to such efforts (which we term international vaccine solidarity). We analyse the levels and predictors of international vaccine solidarity. We surveyed a representative sample of German adults (n = 2019) who participated in a two-wave YouGov online survey (w1: Sep 13-21, 2021 and w2: Oct 4-13, 2021). International vaccine solidarity is measured by asking respondents preferences for sharing vaccine supplies internationally versus using that supply as boosters for the domestic population. We examine a set of pre-registered hypotheses. Almost half of the respondents in our sample (48%) prioritize giving doses to citizens in less developed countries. A third of respondents (33%) prefer to use available doses as boosters domestically, and a fifth of respondents (19%) did not report a preference. In line with our hypotheses, respondents higher in cosmopolitanism and empathy, and those who support domestic redistribution exhibit more support for international dose-sharing. Older respondents (who might be more at risk) do not consistently show less support for vaccine solidarity. These results help us to get a better understanding of the way citizens' form preferences about a mechanism that redistributes medical supplies internationally during a global crisis.
    MeSH term(s) Adult ; Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Vaccines ; Cross-Sectional Studies ; Pandemics/prevention & control ; Vaccines ; Germany/epidemiology ; Vaccination
    Chemical Substances COVID-19 Vaccines ; Vaccines
    Language English
    Publishing date 2023-06-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0287257
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: The added value of establishing a lexicon to help inform, compare, and better understand the implementation of policy, systems, and environmental change strategies in Supplemental Nutrition Assistance Program Education

    Thompson, Jack / Sutton, Katherine / Kuo, Tony

    Preventive Medicine Reports. 2019 June, v. 14

    2019  

    Abstract: Categorization of terms/concepts/constructs that allows for better understanding and comparison of public health interventions is often lacking in program implementation and evaluation. A classification system such as a lexicon, when used appropriately, ... ...

    Abstract Categorization of terms/concepts/constructs that allows for better understanding and comparison of public health interventions is often lacking in program implementation and evaluation. A classification system such as a lexicon, when used appropriately, can help address this need. The present narrative describes a lexicon of policy, systems, and environmental change strategies (PSEs) that was developed and prototyped to aid local implementation of Supplemental Nutrition Assistance Program Education (SNAP-Ed) interventions in obesity prevention. The lexicon was reviewed and refined by a panel of experts who provided iterative feedback on the system's scope and utility. To develop the lexicon, a team from the local health department: (i) conducted an inventory (community context scan) of SNAP-Ed PSEs implemented in Los Angeles County during 2010–2015; (ii) assessed commonalities among PSEs that were translated into “index factors” to contextualize terms/concepts/constructs relevant to SNAP-Ed services planning; and (iii) convened a panel of experts to review and test the classification system for quality and usability. In the latter activity, the panel reviewed the terms/concepts/constructs within the context of two geographical areas and by the selected PSEs. The final version of the lexicon organized the terms/concepts/constructs of the local SNAP-Ed PSEs into overarching categories, so they can be compared/assessed by type, content, and/or impact. The goal of the project was to create a classification system that can help facilitate meaningful communications among program implementers, evaluators, and community stakeholders. The lexicon has practical implications and potential applications for other jurisdictions interested in reducing obesity rates through SNAP-Ed PSEs.
    Keywords Supplemental Nutrition Assistance Program ; education ; inventories ; issues and policy ; medicine ; obesity ; public health ; stakeholders
    Language English
    Dates of publication 2019-06
    Size p. 100873-100878.
    Publishing place Elsevier BV
    Document type Article
    ZDB-ID 2785569-7
    ISSN 2211-3355
    ISSN 2211-3355
    DOI 10.1016/j.pmedr.2019.100873
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  7. Article: Transformation and fate of pharmaceuticals, personal care products, and per- and polyfluoroalkyl substances during aerobic digestion of anaerobically digested sludge

    Li, Yijing / Thompson, Jack / Wang, Zhiyao / Bräunig, Jennifer / Zheng, Qiuda / Thai, Phong K. / Mueller, Jochen F. / Yuan, Zhiguo

    Water research. 2022 July 01, v. 219

    2022  

    Abstract: Post-anaerobic aerobic digestion (PAAD) is a promising strategy to further reduce the volume and improve the quality of anaerobically digested sludge (ADS). However, the effect of PAAD process on the fate of pharmaceuticals and personal care products ( ... ...

    Abstract Post-anaerobic aerobic digestion (PAAD) is a promising strategy to further reduce the volume and improve the quality of anaerobically digested sludge (ADS). However, the effect of PAAD process on the fate of pharmaceuticals and personal care products (PPCPs) and per- and polyfluoroalkyl substances (PFAS) remains largely unknown. In this study, fourteen PPCPs and fifteen PFAS were detected in ADS and evaluated regarding their fate and transformation in a laboratory aerobic digester operated with a hydraulic retention time of 13 days under 22 ℃. Twelve PPCPs demonstrated significant (p < 0.05) decrease in their total concentrations (dissolved and adsorbed fractions combined) with six compounds presenting substantial transformation (> 80%) after aerobic digestion. On the contrary, PFAS were not removed and their concentrations were either increased (increasing ratio: 91 – 571%) or consistent in the sludge during PAAD process, suggesting their recalcitrance to post aerobic digestion. More than half of PPCPs and PFAS demonstrated medium to strong sorption onto solids with their solid fraction higher than 50% in the ADS. After PAAD process, sorption of four PPCPs and three PFAAs to solids was enhanced in sludge.
    Keywords aerobic digestion ; anaerobic digestion ; drugs ; research ; sludge ; sorption ; water
    Language English
    Dates of publication 2022-0701
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 202613-2
    ISSN 1879-2448 ; 0043-1354
    ISSN (online) 1879-2448
    ISSN 0043-1354
    DOI 10.1016/j.watres.2022.118568
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  8. Article: Stamping the vaccine passport? Public support for lifting COVID-19 related restrictions for vaccinated citizens in France, Germany, and Sweden

    Stoeckel, Florian / Stöckli, Sabrina / Phillips, Joseph / Lyons, Benjamin / Mérola, Vittorio / Barnfield, Matthew / Szewach, Paula / Thompson, Jack / Reifler, Jason

    Vaccine. 2022 Aug. 05,

    2022  

    Abstract: During theCOVID-19pandemic,manycountries implementedrestrictionsto limit the spread of the SARS-CoV-2 virus (e.g. travel restrictions and lockdowns).One path to loosening restrictions is to do so selectively only for vaccinated individuals (e.g. by ... ...

    Abstract During theCOVID-19pandemic,manycountries implementedrestrictionsto limit the spread of the SARS-CoV-2 virus (e.g. travel restrictions and lockdowns).One path to loosening restrictions is to do so selectively only for vaccinated individuals (e.g. by implementing vaccine passports domestically or as a prerequisite for international travel).Setting different rules based on people’s vaccination statusis howevera contentious issue among health policy experts, government officials, and the public. Our analysis focuses on the levels and correlates of public support for the lifting of restrictions for the vaccinatedin April 2021, i.e. at a time when restrictions were in place and aselective lifting of these restrictions just for the vaccinatedwas debated in Europe.We use representative quota samples of the populations of France (N = 1,752), Germany (N = 1,759), and Sweden (N = 1,754). We find that a slight plurality support lifting restrictions for the vaccinated in France and Germany but not in Sweden. Vaccine hesitancy emerges as strong predictor of opposition to such a policy. Additionally, individuals who are already vaccinated (in France and Germany) and who are higher in risk-seeking express more support for the lifting of restrictions for the vaccinated. We discuss implications for the debate on vaccine passports.
    Keywords COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; health policy ; travel ; vaccination ; vaccines ; viruses ; France ; Germany ; Sweden
    Language English
    Dates of publication 2022-0805
    Publishing place Elsevier Ltd
    Document type Article
    Note Pre-press version
    ZDB-ID 605674-x
    ISSN 1873-2518 ; 0264-410X
    ISSN (online) 1873-2518
    ISSN 0264-410X
    DOI 10.1016/j.vaccine.2022.08.009
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  9. Article: The added value of establishing a lexicon to help inform, compare, and better understand the implementation of policy, systems, and environmental change strategies in Supplemental Nutrition Assistance Program Education.

    Thompson, Jack / Sutton, Katherine / Kuo, Tony

    Preventive medicine reports

    2019  Volume 14, Page(s) 100873

    Abstract: Categorization of terms/concepts/constructs that allows for better understanding and comparison of public health interventions is often lacking in program implementation and evaluation. A classification system such as a lexicon, when used appropriately, ... ...

    Abstract Categorization of terms/concepts/constructs that allows for better understanding and comparison of public health interventions is often lacking in program implementation and evaluation. A classification system such as a lexicon, when used appropriately, can help address this need. The present narrative describes a lexicon of policy, systems, and environmental change strategies (PSEs) that was developed and prototyped to aid local implementation of Supplemental Nutrition Assistance Program Education (SNAP-Ed) interventions in obesity prevention. The lexicon was reviewed and refined by a panel of experts who provided iterative feedback on the system's scope and utility. To develop the lexicon, a team from the local health department: (i) conducted an inventory (community context scan) of SNAP-Ed PSEs implemented in Los Angeles County during 2010-2015; (ii) assessed commonalities among PSEs that were translated into "index factors" to contextualize terms/concepts/constructs relevant to SNAP-Ed services planning; and (iii) convened a panel of experts to review and test the classification system for quality and usability. In the latter activity, the panel reviewed the terms/concepts/constructs within the context of two geographical areas and by the selected PSEs. The final version of the lexicon organized the terms/concepts/constructs of the local SNAP-Ed PSEs into overarching categories, so they can be compared/assessed by type, content, and/or impact. The goal of the project was to create a classification system that can help facilitate meaningful communications among program implementers, evaluators, and community stakeholders. The lexicon has practical implications and potential applications for other jurisdictions interested in reducing obesity rates through SNAP-Ed PSEs.
    Language English
    Publishing date 2019-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2785569-7
    ISSN 2211-3355
    ISSN 2211-3355
    DOI 10.1016/j.pmedr.2019.100873
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Expanding the indications for the bone anchored hearing system (BAHS) in patients with single sided deafness.

    Wazen, Jack J / Ortega, Carmelo / Nazarian, Ronen / Smith, Joshua / Thompson, Jack / Lange, Linda

    American journal of otolaryngology

    2021  Volume 42, Issue 3, Page(s) 102864

    Abstract: Purpose: Provide data to support expansion of FDA indications for the Bone anchored hearing system (BAHS).: Materials and methods: This retrospective study in a tertiary otologic referral center included106 consecutive subjects who were implanted ... ...

    Abstract Purpose: Provide data to support expansion of FDA indications for the Bone anchored hearing system (BAHS).
    Materials and methods: This retrospective study in a tertiary otologic referral center included106 consecutive subjects who were implanted with a Bone Anchored Hearing System (BAHS) between January 2009 and January 2015 for single sided deafness. Subjects were divided into three groups by bone conduction pure tone average (PTA) of the better hearing ear: 0-20 dB (group 1), 21-40 dB (group 2) and 41-55 dB (group 3). All patients underwent BAHS implantation. Speech perception data (Hearing In Noise Test and Consonant-Nucleus-Consonant testing) was collected before and after surgical intervention. Patient-reported quality of life measures were obtained at least 6 months after activation. These included the Abbreviated Profile of Hearing Aid Benefit and Glasgow Benefit Inventory.
    Results: All three groups of subjects demonstrated statistically significant improvement in outcome measures following BAHS. Subject reported quality of life outcome measures demonstrated significant improvement in disability from hearing loss and in quality of life.
    Conclusions: Patients with single sided deafness who have bone conduction thresholds worse than 20 dB in their contralateral ear are still able to benefit significantly from BAHS.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Audiometry, Pure-Tone ; Bone Conduction ; Cochlear Implantation/methods ; Differential Threshold ; Female ; Hearing ; Hearing Aids ; Hearing Loss, Unilateral/diagnosis ; Hearing Loss, Unilateral/physiopathology ; Hearing Loss, Unilateral/rehabilitation ; Humans ; Middle Aged ; Quality of Life ; Retrospective Studies ; Suture Anchors ; Young Adult
    Language English
    Publishing date 2021-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2020.102864
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top