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  1. Article ; Online: Current Concepts in Head and Neck Surgery.

    Bertran, Judith / Thomson, Alexander C S

    The Veterinary clinics of North America. Small animal practice

    2022  Volume 52, Issue 2, Page(s) 489–512

    Abstract: This article is intended to "brush up" on the literature updates for the management of head and neck surgeries, particularly mandibulectomy and maxillectomy. Few new techniques have been described in the past decade in dental and oral oncological surgery. ...

    Abstract This article is intended to "brush up" on the literature updates for the management of head and neck surgeries, particularly mandibulectomy and maxillectomy. Few new techniques have been described in the past decade in dental and oral oncological surgery. A tendency of developing more aggressive surgical strategies to treat complex oral tumors is evident from the recent veterinary literature and the emerging novel techniques for bone regeneration of maxillofacial defects. In addition, this article also focuses on the basic oral surgical oncology principles, an important part of any maxillofacial surgery.
    MeSH term(s) Animals ; Head and Neck Neoplasms/surgery ; Head and Neck Neoplasms/veterinary ; Surgery, Oral/methods
    Language English
    Publishing date 2022-01-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 757662-6
    ISSN 1878-1306 ; 0195-5616
    ISSN (online) 1878-1306
    ISSN 0195-5616
    DOI 10.1016/j.cvsm.2021.12.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Use of a thoracic paravertebral catheter to control severe trauma-related pain in a dog.

    Thomson, Alexander C S / Portela, Diego A

    Veterinary anaesthesia and analgesia

    2021  Volume 48, Issue 5, Page(s) 809–811

    MeSH term(s) Animals ; Catheters ; Dog Diseases ; Dogs ; Nerve Block/veterinary ; Pain/etiology ; Pain/prevention & control ; Pain/veterinary ; Pain, Postoperative/veterinary ; Thoracic Vertebrae
    Language English
    Publishing date 2021-06-06
    Publishing country United States
    Document type Letter
    ZDB-ID 2020582-X
    ISSN 1467-2995 ; 1467-2987
    ISSN (online) 1467-2995
    ISSN 1467-2987
    DOI 10.1016/j.vaa.2021.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Anesthesia Case of the Month.

    Thomson, Alexander C S / Romano, Marta / Portela, Diego A

    Journal of the American Veterinary Medical Association

    2020  Volume 256, Issue 11, Page(s) 1219–1222

    MeSH term(s) Anesthesia/adverse effects ; Anesthesia/veterinary ; Animals
    Language English
    Publishing date 2020-05-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.256.11.1219
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Anesthesia Case of the Month.

    Thomson, Alexander C S / Gatson, Bonnie J / Bertran, Judith

    Journal of the American Veterinary Medical Association

    2020  Volume 257, Issue 7, Page(s) 710–713

    MeSH term(s) Anesthesia/adverse effects ; Anesthesia/veterinary ; Animals
    Language English
    Publishing date 2020-10-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.257.7.710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Pharmacokinetics and tolerability of single-dose enteral cannabidiol and cannabidiolic acid rich hemp in horses (

    Thomson, Alexander C S / McCarrel, Taralyn M / Zakharov, Alexander / Gomez, Beatriz / Lyubimov, Alex / Schwark, Wayne S / Mallicote, Martha F / Portela, Diego A / Bisiau, Amber L / Wakshlag, Joseph J

    Frontiers in veterinary science

    2024  Volume 11, Page(s) 1356463

    Abstract: The pharmacokinetics and tolerability of cannabinoids and their metabolites were determined in eight horses after enteral administration of a commercial CBD/CBDA-rich hemp oil product. Each horse was administered 2 mg/kg or 8 mg/kg CBD/CBDA or no ... ...

    Abstract The pharmacokinetics and tolerability of cannabinoids and their metabolites were determined in eight horses after enteral administration of a commercial CBD/CBDA-rich hemp oil product. Each horse was administered 2 mg/kg or 8 mg/kg CBD/CBDA or no treatment in a randomized cross-over design. Serial serum samples collected over 48 h were analyzed by high performance liquid chromatography with tandem mass spectrometry. Plasma chemistry analysis was performed at 0 h and 24 h. Vital parameters, pedometry, and blinded mentation and gait evaluations were recorded at intervals up to 24 h. Manure production and gastrointestinal transit time were tracked for 48 h after oil administration. The median maximal concentration of CBD and CBDA were 5.2 and 36.95 ng/mL in the 2 mg/kg group, respectively; and 40.35 and 353.56 ng/mL in the 8 mg/kg group. The median half-life of elimination was not calculated for the 2 mg/kg CBD treatment due to lack of time points above the lower quantifiable limit beyond the Cmax while it was 7.75 h in the 8 mg/kg group. CBDA absorption was biphasic. Pharmacokinetic parameters for tetrahydrocannabinol, tetrahydrocannabinolic acid, cannabigerolic acid, and 7-carboxy cannabidiol are also reported. No significant differences in any of the measured tolerability parameters were demonstrated between treatment groups. Single-dose enteral administration of CBD/CBDA-rich hemp extract up to 8 mg/kg does not appear to produce neurologic, behavioral, or gastrointestinal effects in horses.
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2024.1356463
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Evaluation of the effect of ultrasound guidance on the accuracy of intercostal nerve injection: a canine cadaveric study.

    Thomson, Alexander C S / Portela, Diego A / Romano, Marta / Otero, Pablo E

    Veterinary anaesthesia and analgesia

    2020  Volume 48, Issue 2, Page(s) 256–263

    Abstract: Objective: To develop an ultrasound-guided approach to intercostal nerve injection and to compare the success rate of intercostal nerve injections using blind or ultrasound-guided technique in canine cadavers.: Study design: Prospective, randomized, ... ...

    Abstract Objective: To develop an ultrasound-guided approach to intercostal nerve injection and to compare the success rate of intercostal nerve injections using blind or ultrasound-guided technique in canine cadavers.
    Study design: Prospective, randomized, descriptive, experimental anatomic study.
    Animals: A total of 14 mid-sized adult canine cadavers.
    Methods: Ultrasound landmarks were identified by dissection of four cadavers and used to develop an ultrasound-guided technique. The remaining 10 cadavers were randomly assigned to blind (five cadavers) or ultrasound-guided (five cadavers) injections of the third to the ninth intercostal nerves bilaterally with 0.03 mL kg
    Results: Success rates of blind and ultrasound-guided technique were 57.1% and 91.4%, respectively (p < 0.0001). The length of intercostal nerve staining was 3.1 ± 1.2 cm and 3.6 ± 1.0 cm using blind and ultrasound-guided techniques, respectively (p = 0.02). No differences were observed between the two practitioners for blind (p = 0.33) and ultrasound-guided techniques (p = 0.67).
    Conclusions and clinical relevance: Ultrasound guidance improves the accuracy of intercostal nerve injections when compared with blind technique, independently of the level of expertise in regional anesthesia.
    MeSH term(s) Animals ; Cadaver ; Dog Diseases ; Dogs ; Intercostal Nerves/diagnostic imaging ; Nerve Block/veterinary ; Prospective Studies ; Ultrasonography, Interventional/veterinary
    Language English
    Publishing date 2020-12-30
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial, Veterinary
    ZDB-ID 2020582-X
    ISSN 1467-2995 ; 1467-2987
    ISSN (online) 1467-2995
    ISSN 1467-2987
    DOI 10.1016/j.vaa.2020.12.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Evaluation of the effect of ultrasound guidance on the accuracy of intercostal nerve injection: a canine cadaveric study

    Thomson, Alexander C.S / Portela, Diego A / Romano, Marta / Otero, Pablo E

    Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia Veterinary anaesthesia and analgesia. 2020 Dec. 07,

    2020  

    Abstract: To develop an ultrasound-guided approach to intercostal nerve injection and to compare the success rate of intercostal nerve injections using blind or ultrasound-guided technique in canine cadavers.Prospective, randomized, descriptive, experimental ... ...

    Abstract To develop an ultrasound-guided approach to intercostal nerve injection and to compare the success rate of intercostal nerve injections using blind or ultrasound-guided technique in canine cadavers.Prospective, randomized, descriptive, experimental anatomic study.A total of 14 mid-sized adult canine cadavers.Ultrasound landmarks were identified by dissection of four cadavers and used to develop an ultrasound-guided technique. The remaining 10 cadavers were randomly assigned to blind (five cadavers) or ultrasound-guided (five cadavers) injections of the third to the ninth intercostal nerves bilaterally with 0.03 mL kg–¹ of colorant per injection. The target for intercostal injections was the caudal border of the respective rib, between the internal intercostal membrane and the parietal pleura. Additionally, displacement of the parietal pleura without visible intramuscular distribution was considered the end point for ultrasound-guided injections. For each cadaver, a practitioner in training performed the blocks on one hemithorax, while an experienced practitioner performed the blocks on the opposite hemithorax. Injections were considered successful if ≥1 cm of the target nerve was stained with colorant upon dissection. Success rates and length of nerve staining were analyzed with Fisher’s exact and t tests, respectively. Data were considered statistically different with p < 0.05.Success rates of blind and ultrasound-guided technique were 57.1% and 91.4%, respectively (p < 0.0001). The length of intercostal nerve staining was 3.1 ± 1.2 cm and 3.6 ± 1.0 cm using blind and ultrasound-guided techniques, respectively (p = 0.02). No differences were observed between the two practitioners for blind (p = 0.33) and ultrasound-guided techniques (p = 0.67).Ultrasound guidance improves the accuracy of intercostal nerve injections when compared with blind technique, independently of the level of expertise in regional anesthesia.
    Keywords accuracy ; adults ; analgesia ; anesthesia ; cadaver ; dogs ; dyes ; injection ; length ; nerve tissue ; pleura ; staining ; ultrasonics ; ultrasonography
    Language English
    Dates of publication 2020-1207
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-light ; Pre-press version
    ZDB-ID 2020582-X
    ISSN 1467-2995 ; 1467-2987
    ISSN (online) 1467-2995
    ISSN 1467-2987
    DOI 10.1016/j.vaa.2020.12.003
    Database NAL-Catalogue (AGRICOLA)

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