Article ; Online: Evaluation of aversive behavior in Rattus norvegicus experimentally infected by two distinct strains of Toxoplasma gondii (ME49 and VEG): study of epigenetic markers.
Revista da Sociedade Brasileira de Medicina Tropical
2022 Volume 55, Page(s) e01222022
Abstract: Background: Behavioral changes in Rattus norvegicus infected with two strains of Toxoplasma gondii (ME49 and VEG) were investigated.: Methods: Rats were evaluated for motor activity and aversion or attraction to cat urine 60 days after infection. ... ...
Abstract | Background: Behavioral changes in Rattus norvegicus infected with two strains of Toxoplasma gondii (ME49 and VEG) were investigated. Methods: Rats were evaluated for motor activity and aversion or attraction to cat urine 60 days after infection. After euthanasia, arginine-vasopressin gene methylation in the central nervous system was evaluated. Results: A significant difference was observed in the methylation of the arginine-vasopressin promoter gene between rats infected with the ME49 and VEG strains. Conclusions: Although differences were not observed in many parameters, significant differences were observed in the methylation of the arginine-vasopressin promoter gene in rats infected with the two studied strains. |
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MeSH term(s) | Rats ; Animals ; Toxoplasma/genetics ; Behavior, Animal/physiology ; Epigenesis, Genetic ; Vasopressins/genetics ; Arginine/genetics ; Toxoplasmosis, Animal | |||||
Chemical Substances | Vasopressins (11000-17-2) ; Arginine (94ZLA3W45F) | |||||
Language | English | |||||
Publishing date | 2022-10-24 | |||||
Publishing country | Brazil | |||||
Document type | Journal Article | |||||
ZDB-ID | 1038126-0 | |||||
ISSN | 1678-9849 ; 0037-8682 | |||||
ISSN (online) | 1678-9849 | |||||
ISSN | 0037-8682 | |||||
DOI | 10.1590/0037-8682-0122-2022 | |||||
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Database | MEDical Literature Analysis and Retrieval System OnLINE |
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