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  1. Article ; Online: A firm-level analysis of Chinese commercial health insurance surrender.

    Tian, Ling / Dong, Haisong

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0296695

    Abstract: Based on the unbalanced panel data of Chinese professional health insurance companies from 2011 to 2021, the paper constructs "PW+PCSE" model to empirically investigate the main factors affecting the commercial health insurance surrender in China from ... ...

    Abstract Based on the unbalanced panel data of Chinese professional health insurance companies from 2011 to 2021, the paper constructs "PW+PCSE" model to empirically investigate the main factors affecting the commercial health insurance surrender in China from the company level. The results show that asset-liability ratio has a significant positive effect on health insurance surrender rate. The value preservation and appreciation rate of capital and R&D expenditure rate both have significant negative effects on health insurance surrender rate. These studies bring important enlightenment for domestic health insurance companies to avoid surrender risk.
    MeSH term(s) Insurance, Health ; Insurance, Liability ; Health Expenditures ; China
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0296695
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Study on the Dynamic Relationship between Chinese Residents' Individual Characteristics and Commercial Health Insurance Demand.

    Tian, Ling / Dong, Haisong

    International journal of environmental research and public health

    2023  Volume 20, Issue 6

    Abstract: Based on the time series data of age characteristics, household registration characteristics, gender characteristics, education characteristics, marriage characteristics and commercial health insurance density of Chinese residents from 1997 to 2020, this ...

    Abstract Based on the time series data of age characteristics, household registration characteristics, gender characteristics, education characteristics, marriage characteristics and commercial health insurance density of Chinese residents from 1997 to 2020, this paper aims to explore the dynamic relationship between the individual characteristics of Chinese residents and the demand for commercial health insurance by means of impulse response and variance decomposition analysis using an SVAR model. The results show that the age characteristics, household registration characteristics, gender characteristics, education characteristics and marriage characteristics of Chinese residents have a significant impact on the demand for commercial health insurance, but there is a time lag. There is a long-term equilibrium relationship between them: In terms of age characteristics and gender characteristics, the former has a positive effect in the short term and a significant inhibition on commercial health insurance demand in the long term, while the latter has the opposite. In terms of household registration characteristics, education characteristics and marriage characteristics, there are positive effects on the whole and negative effects in a particular period.
    MeSH term(s) Humans ; East Asian People ; Educational Status ; Family Characteristics ; Insurance, Health ; China
    Language English
    Publishing date 2023-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20064797
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  3. Article ; Online: Family Life Cycle, Asset Portfolio, and Commercial Health Insurance Demand in China.

    Tian, Ling / Dong, Haisong

    International journal of environmental research and public health

    2022  Volume 19, Issue 24

    Abstract: Based on the cross-sectional data of the China household finance survey (CHFS) in 2017, this paper aims to empirically examine the effects of the family life cycle, financial status, and asset portfolio on commercial health insurance demand (breadth and ... ...

    Abstract Based on the cross-sectional data of the China household finance survey (CHFS) in 2017, this paper aims to empirically examine the effects of the family life cycle, financial status, and asset portfolio on commercial health insurance demand (breadth and depth) by constructing Probit and Tobit models, respectively. Based on all of the samples, it has been found that family life cycle, family financial status, and family asset portfolio have different influences on the breadth and the depth of health insurance. In terms of the family life cycle, there is an "inverted U-shaped" relationship with the breadth and the depth of health insurance, and the effect is obvious. In terms of family financial status, total household consumption has positive and significant effects on the breadth and depth of health insurance. Total household income and total household debt only have a significant positive impact on health insurance breadth. The total household asset portfolio is only positively correlated with health insurance depth. In terms of the family asset portfolio, the share of real estate assets has a crowding out effect on the breadth and the depth of health insurance. The share of savings assets has no significant effect on the breadth and the depth of health insurance but is positively correlated with the former and negatively correlated with the latter. Both the share of vehicle assets and the share of investment assets only have a significant impact on the breadth of health insurance; however, the positive and negative correlation is different. Based on the sub-samples, it has been found that the breadth and the depth of health insurance vary greatly in the regions and household registration characteristics.
    MeSH term(s) Cross-Sectional Studies ; Insurance, Health ; Income ; China ; Family
    Language English
    Publishing date 2022-12-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph192416795
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  4. Article ; Online: Recent Progress in Long-Term Sleep Monitoring Technology.

    Yin, Jiaju / Xu, Jiandong / Ren, Tian-Ling

    Biosensors

    2023  Volume 13, Issue 3

    Abstract: Sleep is an essential physiological activity, accounting for about one-third of our lives, which significantly impacts our memory, mood, health, and children's growth. Especially after the COVID-19 epidemic, sleep health issues have attracted more ... ...

    Abstract Sleep is an essential physiological activity, accounting for about one-third of our lives, which significantly impacts our memory, mood, health, and children's growth. Especially after the COVID-19 epidemic, sleep health issues have attracted more attention. In recent years, with the development of wearable electronic devices, there have been more and more studies, products, or solutions related to sleep monitoring. Many mature technologies, such as polysomnography, have been applied to clinical practice. However, it is urgent to develop wearable or non-contacting electronic devices suitable for household continuous sleep monitoring. This paper first introduces the basic knowledge of sleep and the significance of sleep monitoring. Then, according to the types of physiological signals monitored, this paper describes the research progress of bioelectrical signals, biomechanical signals, and biochemical signals used for sleep monitoring. However, it is not ideal to monitor the sleep quality for the whole night based on only one signal. Therefore, this paper reviews the research on multi-signal monitoring and introduces systematic sleep monitoring schemes. Finally, a conclusion and discussion of sleep monitoring are presented to propose potential future directions and prospects for sleep monitoring.
    MeSH term(s) Child ; Humans ; Polysomnography ; COVID-19 ; Sleep/physiology ; Wearable Electronic Devices
    Language English
    Publishing date 2023-03-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios13030395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Role of PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma Metabolism.

    Tian, Ling-Yu / Smit, Daniel J / Jücker, Manfred

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in the world. Metabolic reprogramming is considered a new hallmark of cancer, but it remains unclearly described in HCC. The dysregulation of the PI3K/AKT/mTOR signaling ...

    Abstract Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths in the world. Metabolic reprogramming is considered a new hallmark of cancer, but it remains unclearly described in HCC. The dysregulation of the PI3K/AKT/mTOR signaling pathway is common in HCC and is, therefore, a topic of further research and the concern of developing a novel target for liver cancer therapy. In this review, we illustrate mechanisms by which this signaling network is accountable for regulating HCC cellular metabolism, including glucose metabolism, lipid metabolism, amino acid metabolism, pyrimidine metabolism, and oxidative metabolism, and summarize the ongoing clinical trials based on the inhibition of the PI3K/AKT/mTOR pathway in HCC.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/metabolism ; Liver Neoplasms/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Cell Line, Tumor ; Signal Transduction/physiology ; TOR Serine-Threonine Kinases/metabolism
    Chemical Substances Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; TOR Serine-Threonine Kinases (EC 2.7.11.1) ; MTOR protein, human (EC 2.7.1.1)
    Language English
    Publishing date 2023-01-31
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24032652
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Multi-physics coupling in nanoscale spintronics and quantum devices.

    Zhang, Gang / Cheng, Yuan / Ren, Tian-Ling

    Nanotechnology

    2023  Volume 34, Issue 50

    Language English
    Publishing date 2023-10-05
    Publishing country England
    Document type Editorial
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/acefd6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Omentum pregnancy developed over 3 months: a case report.

    Tian, Ling / Shan, Wanjun / Wang, Yu

    Archives of gynecology and obstetrics

    2023  Volume 308, Issue 6, Page(s) 1887–1889

    Language English
    Publishing date 2023-04-29
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-023-07050-4
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    In stock of ZB MED Cologne/Königswinter

    Um I Zs.55: Show issues Location:
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  8. Article: Growth and Physiological Responses of Magnoliaceae to NaCl Stress.

    Zhao, Xiuting / Tian, Ling / Zhu, Zhonglong / Sang, Ziyang / Ma, Lvyi / Jia, Zhongkui

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 2

    Abstract: The growth and physiological characteristics of four Magnoliaceae plants ( ...

    Abstract The growth and physiological characteristics of four Magnoliaceae plants (
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13020170
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  9. Article ; Online: Correlation between soluble klotho and chronic kidney disease-mineral and bone disorder in chronic kidney disease: a meta-analysis.

    Fan, Zhongyu / Wei, Xuejiao / Zhu, Xiaoyu / Yang, Kun / Tian, Ling / Du, Yujun / Yang, Liming

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4477

    Abstract: We conducted a systematic search across medical databases, including PubMed, Web of Science, EMBASE, and Cochrane Library, up to March 2023. A total of 1944 subjects or individuals from 17 studies were included in our final analysis. The correlation ... ...

    Abstract We conducted a systematic search across medical databases, including PubMed, Web of Science, EMBASE, and Cochrane Library, up to March 2023. A total of 1944 subjects or individuals from 17 studies were included in our final analysis. The correlation coefficient (r) between sKlotho and calcium was [0.14, (0.02, 0.26)], and a moderate heterogeneity was observed (I
    MeSH term(s) Humans ; Calcium ; Chronic Kidney Disease-Mineral and Bone Disorder ; Parathyroid Hormone ; Renal Insufficiency, Chronic/complications ; Vascular Calcification
    Chemical Substances Calcium (SY7Q814VUP) ; Parathyroid Hormone ; KL protein, human (EC 3.2.1.31)
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-54812-4
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  10. Article: Transforming cancer cells for long-term living with cancer: An inspiring new approach.

    Jiang, Mingjie / Gu, Dianna / Liu, Furao / Lin, Chenjing / Tian, Ling

    Chinese journal of cancer research = Chung-kuo yen cheng yen chiu

    2023  Volume 35, Issue 2, Page(s) 108–125

    Abstract: Cancer is the leading cause of human death and imposes a huge health burden. Currently, no matter what advanced therapeutic modalities or technologies are applied, it is still peculiarly rare for most cancers to be radically cured whereas therapy ... ...

    Abstract Cancer is the leading cause of human death and imposes a huge health burden. Currently, no matter what advanced therapeutic modalities or technologies are applied, it is still peculiarly rare for most cancers to be radically cured whereas therapy resistance and tumor recurrence are ever so common. The long-standing cytotoxic therapy is hard to achieve long-term tumor control, and produces side-effects or even promotes cancer progression. With growing understandings of tumor biology, we came to realize that it is possible to transform but not kill cancer cells to achieve long-term living with cancer, and directly altering cancer cells is a promising way. Remarkably, tissue microenvironment is involved in the fate determination of cancer cells. Of note, leveraging cell competition to combat malignant or therapy-resistant cells shows some therapeutic potentials. Furthermore, modulating tumor microenvironment to restore a normal state might help to transform cancer cells. Especially, reprogramming cancer-associated fibroblasts, and tumor-associated macrophages, or normalization of tumor vessel, tumor immune microenvironment, and tumor extracellular matrix or their combinations,
    Language English
    Publishing date 2023-03-30
    Publishing country China
    Document type Journal Article
    ZDB-ID 1067584-x
    ISSN 1993-0631 ; 1000-9604
    ISSN (online) 1993-0631
    ISSN 1000-9604
    DOI 10.21147/j.issn.1000-9604.2023.02.03
    Database MEDical Literature Analysis and Retrieval System OnLINE

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