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  1. Article ; Online: A propensity score-matched analysis of laparoscopic versus open pancreaticoduodenectomy: Is there value to a laparoscopic approach?

    Stauffer, John A / Hyman, David / Porrazzo, Gina / Tice, Mary / Li, Zhuo / Almerey, Tariq

    Surgery

    2024  Volume 175, Issue 4, Page(s) 1162–1167

    Abstract: Background: Laparoscopic pancreaticoduodenectomy has been found safe and associated with advantages over open pancreaticoduodenectomy in prior studies. We compared outcomes of laparoscopic pancreaticoduodenectomy versus open pancreaticoduodenectomy at a ...

    Abstract Background: Laparoscopic pancreaticoduodenectomy has been found safe and associated with advantages over open pancreaticoduodenectomy in prior studies. We compared outcomes of laparoscopic pancreaticoduodenectomy versus open pancreaticoduodenectomy at a single institution after applying technical aspects and perioperative care learned from laparoscopic pancreaticoduodenectomy to the open pancreaticoduodenectomy practice.
    Methods: From January 2010 to December 2020, all patients undergoing pancreaticoduodenectomy were identified, and information was collected in a prospective fashion. Open pancreaticoduodenectomy (n = 347) and laparoscopic pancreaticoduodenectomy (n = 242) were performed using the same selection criteria, operative technique, and recovery protocols at a single institution. Propensity score matching was performed, and then perioperative data and 90-day outcomes were compared, and statistical analysis was performed.
    Results: A total of 589 patients underwent pancreaticoduodenectomy, including open pancreaticoduodenectomy (n = 347) and laparoscopic pancreaticoduodenectomy (n = 242). After excluding those undergoing total pancreatectomy or major vascular or concomitant organ resection, there were 497 patients (open pancreaticoduodenectomy = 301 and laparoscopic pancreaticoduodenectomy = 196). Propensity score matching was performed, and 187 open pancreaticoduodenectomy patients were matched to 187 laparoscopic pancreaticoduodenectomy patients. Operative time (475 vs 280 minutes) was longer, and estimated blood loss (150 vs 212 mL) was less for laparoscopic pancreaticoduodenectomy than open pancreaticoduodenectomy, respectively. Pancreatic fistula (18.8% vs 5.4%) and delayed gastric emptying (18.8% vs 9.7%) were higher for laparoscopic pancreaticoduodenectomy than open pancreaticoduodenectomy, respectively. Postpancreatectomy hemorrhage, major morbidity, mortality, hospital stay, and readmissions were nonsignificantly higher for laparoscopic pancreaticoduodenectomy than open pancreaticoduodenectomy. Intensive care use and overall costs were significantly higher for laparoscopic pancreaticoduodenectomy than open pancreaticoduodenectomy.
    Conclusion: In our experience, open pancreaticoduodenectomy offers similar to improved outcomes over laparoscopic pancreaticoduodenectomy, with less use of perioperative resources, thereby offering better value to patients requiring pancreaticoduodenectomy.
    MeSH term(s) Humans ; Pancreaticoduodenectomy/adverse effects ; Pancreaticoduodenectomy/methods ; Pancreatic Neoplasms/surgery ; Propensity Score ; Pancreatectomy ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Retrospective Studies ; Length of Stay
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202467-6
    ISSN 1532-7361 ; 0039-6060
    ISSN (online) 1532-7361
    ISSN 0039-6060
    DOI 10.1016/j.surg.2023.12.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comparing Post-Operative Outcomes of Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma: Neoadjuvant Therapy Versus Surgery First Approach.

    Hyman, David W / Almerey, Tariq / Mujkanovic, Amer / Hammons, Isaac / Tice, Mary / Stauffer, John A

    The American surgeon

    2022  Volume 88, Issue 8, Page(s) 1868–1874

    Abstract: Objectives: Optimal use of surgery first (SF) vs neoadjuvant therapy (NAT) for localized pancreatic ductal adenocarcinoma (PDAC) is still unclear. There is concern that NAT may result in worsened post-operative outcomes. Our study objectives were to ... ...

    Abstract Objectives: Optimal use of surgery first (SF) vs neoadjuvant therapy (NAT) for localized pancreatic ductal adenocarcinoma (PDAC) is still unclear. There is concern that NAT may result in worsened post-operative outcomes. Our study objectives were to show the impact of NAT on post-operative morbidity and mortality.
    Methods: All patients undergoing resection for PDAC between 1/1/2010 and 12/31/2020 were reviewed and those who underwent pancreaticoduodenectomy (PD) were included. Demographics, perioperative details, and pathology details were gathered. Data pertaining to 90-day complications were obtained and graded according to international consensus guidelines. Those undergoing SF were compared to those who had NAT. Categorical variables were compared by Fisher's exact test and continuous variables by Student's t-test.
    Results: Two hundred and forty-one subjects who underwent PD for PDAC were included in this review. There was no significant difference in the rate of major morbidity between subjects who received NAT vs SF (19.4 vs 20.3%,
    Conclusion: Post-operative outcomes are not worsened by the use of the NAT approach prior to PD for PDAC. Further investigation is needed to reveal which patient subgroups may benefit from the use of NAT, especially regarding survival.
    MeSH term(s) Adenocarcinoma/surgery ; Carcinoma, Pancreatic Ductal/surgery ; Humans ; Neoadjuvant Therapy/adverse effects ; Pancreatectomy/adverse effects ; Pancreatic Neoplasms/pathology ; Pancreaticoduodenectomy/adverse effects ; Postoperative Complications/etiology ; Retrospective Studies ; Pancreatic Neoplasms
    Language English
    Publishing date 2022-04-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/00031348221087900
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Tectonic synthesis of the Olympic Mountains segment of the Cascadia wedge, using two‐dimensional thermal and kinematic modeling of thermochronological ages

    Batt, Geoffrey E. / Brandon, Mark T. / Farley, Kenneth A. / Roden‐Tice, Mary

    Journal of Geophysical Research: Solid Earth. 2001 Nov. 10, v. 106, no. B11 p.26731-26746

    2001  

    Abstract: A fully coupled two‐dimensional kinematic and thermal model of a steady state accretionary wedge, constrained by an extensive data set of fission track and (U‐Th)/He ages for apatite and zircon, is here used to investigate the development of the Olympic ... ...

    Abstract A fully coupled two‐dimensional kinematic and thermal model of a steady state accretionary wedge, constrained by an extensive data set of fission track and (U‐Th)/He ages for apatite and zircon, is here used to investigate the development of the Olympic Mountains segment of the Cascadia accretionary wedge. The model has two main free parameters: , the maximum rate of erosion for a generic erosion function operating at the top of the wedge, and α, the distribution of sedimentary accretion into the wedge. The best fit values for and α and their confidence limits are determined through an iterative search of parameter space. This study represents the first time that such inversion methods have been used to quantify the thermal‐kinematic evolution of an accretionary wedge. Our results suggest that horizontal transport plays an important role in the exhumation trajectories experienced by material passing through the Cascadia wedge. At a 95% confidence interval, 80 to 100% of the sedimentary sequence from the subducting Juan de Fuca Plate has been accreted at the front of the wedge offshore of the Olympics over the past 14 m.y. This frontally accreted material must then traverse the entire width of the wedge prior to its eventual exposure in the Olympic forearc high. Assessed in this two‐dimensional framework, the fission track and (U‐Th)/He age data sets from the Olympic Mountains are all best fit by of 0.9-1.0 mm yr⁻¹, despite variation in the timescales relevant to the three chronometers. This result supports the hypothesis that the Olympic Mountains segment of the Cascadia accretionary wedge has been in a flux steady‐state since ∼14 Ma. The demonstration of a flux balance across the Cascadia margin also suggests that margin‐parallel transport has not had a significant role in driving uplift of the Olympic Mountains.
    Keywords apatite ; confidence interval ; data collection ; evolution ; geophysics ; models ; research ; sports ; tectonics ; thermochronology ; zircon
    Language English
    Dates of publication 2001-1110
    Size p. 26731-26746.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 710256-2
    ISSN 2169-8996 ; 2169-897X ; 0148-0227
    ISSN (online) 2169-8996
    ISSN 2169-897X ; 0148-0227
    DOI 10.1029/2001JB000288
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Cretaceous Sedimentary Blanketing and Tectonic Rejuvenation in the Western Klamath Mountains: Insights from Thermochronology

    Batt, Geoffrey (John de Laeter Centre of Mass Spectrometry, University of Western Australia, Crawley, WA6009, Australia) / Harper, Gregory (Formerly at Department of Earth and Atmospheric Sciences, University at Albany, Albany, NY 12222, USA) / Heizler, Matthew (New Mexico Bureau of Geology & Mineral Resources, New Mexico Tech, 801 Leroy Place, Socorro NM 87801-4796, USA) / Roden-Tice, Mary (Center for Earth and Environmental Science, State University of New York at Plattsburgh, Plattsburgh, New York, USA)

    Central European Journal of Geosciences

    2010  

    Abstract: We present new thermochronometric analyses of 4 samples from the Western Klamath mountains in California and Oregon, together with a re-evaluation of available geological constraint from a thermo-tectonic perspective. Early Cretaceous cooling of basement ...

    Abstract We present new thermochronometric analyses of 4 samples from the Western Klamath mountains in California and Oregon, together with a re-evaluation of available geological constraint from a thermo-tectonic perspective. Early Cretaceous cooling of basement samples is seen to reflect significant exhumation by normal faulting, linked to the Separation Episode during which the Klamath region was rifted away from the formerly contiguous Sierra Nevada block. Syn-faulting sedimentation and subsequent Early Cretaceous re-heating of samples establishes the former continuity of scattered Hornbrook Formation remnants as a significant sedimentary basin spanning the Klamath region, with local maximum thickness of at least 5 km. This basin experienced significant inversion during early Cordilleran development around 110-120 Ma, with further unroofing and almost complete eversion in the Late Cretaceous, associated with Laramide uplift of the region.
    Language English
    Document type Article
    ISSN 1896-1517
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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  5. Book: The anatomy and histology of some of the systems of the male of the imported fire ant, Solenopsis saevissima richteri Forel (Hymenoptera: Formicidae)

    Tice, Mary Claudia

    1  

    Keywords Solenopsis saevissima richteri.
    Language English
    Size 108 l. illus.
    Publishing place New York
    Document type Book
    Note Thesis-Fordham University. Authorized facsimile by University Microfilms, Ann Arbor, 1969. Bibliography: leaves 101-108.
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: Apatite fission-track evidence for the Cretaceous development of kilometer-scale relief and steady-state Tertiary topography in New England

    Roden-Tice, Mary K. / Eusden, J. Dykstra, Jr. / Wintsch, Robert P.

    Geomorphology

    Volume v. 141-142

    Abstract: Apatite fission track (AFT) ages in samples collected along the 5000 foot relief (1500m) exposed at Mt. Washington in the Presidential Range of New Hampshire are used to constrain the Cretaceous cooling history of this area in the northern Appalachians. ... ...

    Abstract Apatite fission track (AFT) ages in samples collected along the 5000 foot relief (1500m) exposed at Mt. Washington in the Presidential Range of New Hampshire are used to constrain the Cretaceous cooling history of this area in the northern Appalachians. Nine AFT ages for samples of the Littleton and Rangeley formations collected along this profile range in age from ~150Ma at the highest elevations of ~1900m to ~100Ma at the base (~500m). Thermal histories based on these results and on model time–temperature histories based on the distribution of fission track lengths in the higher elevations samples show three stages of cooling, from 1.5–2.0°C/m.y. (170–130Ma) to 0.2°C (130–65Ma), to ~0.6°C/m.y. (65Ma to the present). In contrast, the thermal history calculated for the lower elevations sample shows cooling delayed until ~120Ma at ~2°C/m.y. (120–100Ma), followed by monotonic cooling of ~0.6°C/m.y. from 100Ma to the present. The convergence of these histories from high, intermediate, and low elevations suggests a common cooling history independent of elevation differences of >1km. Structural/tectonic explanations for this thermal convergence are implausible, and we conclude that the most likely explanation for the common cooling history across >1km of relief is that the relief was established by the end of the Cretaceous and has persisted with steady-state topography through the Tertiary to the present. The AFT results are consistent with an earlier relief method study employing ⁴⁰Ar/³⁹Ar muscovite cooling ages. Geothermal gradients calculated from the results of both studies yield ~40°C/km suggesting that this gradient persisted throughout Permian and Mesozoic times.
    Keywords apatite ; topography ; muscovite ; cooling ; tectonics
    Language English
    Document type Article
    ISSN 0169-555X
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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