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  1. Article ; Online: Environmental, economic and socio-cultural risk factors of recurrent seasonal epidemics of cerebrospinal meningitis in Kebbi state, northwestern Nigeria: a qualitative approach.

    Omoleke, Semeeh A / Alabi, Olatunji / Shuaib, Faisal / Braka, Fiona / Tegegne, Sisay G / Umeh, Gregory C / Ticha, Johnson M / Onimisin, Anthony / Nsubuga, Peter / Adamu, Usman / Mohammed, Kabiru / Onoka, Chima / Alemu, Wondimagegnehu

    BMC public health

    2018  Volume 18, Issue Suppl 4, Page(s) 1318

    Abstract: Background: Kebbi State remains the epicentre of the seasonal epidemic meningitis in northwestern Nigeria despite interventions. In this setting, no previous study has been conducted to understand the risk factors of the recurrent meningitis epidemics ... ...

    Abstract Background: Kebbi State remains the epicentre of the seasonal epidemic meningitis in northwestern Nigeria despite interventions. In this setting, no previous study has been conducted to understand the risk factors of the recurrent meningitis epidemics using qualitative approach. Consequently, this study intends to explore and better understand the environmental, economic and socio-cultural factors of recurrent seasonal epidemic meninigitis using a qualitative approach.
    Methods: We conducted in-depth interview (40 IDIs) and focus group discussions (6 FGDs) in two local government areas (LGAs) in Kebbi State, Northwestern Nigeria to understand the environmental, economic and socio-cultural factors of recurrent meningitis outbreaks. Routine surveillance data were used to guide the selection of settlements, wards and local government areas based on the frequency of re-occurrences and magnitude of the outbreaks.
    Results: The discussions revealed certain elements capable of potentiating the recurrence of seasonal meningitis epidemics. These are environmental issues, such as poorly-designed built environment, crowded sleeping and poorly ventilated rooms, dry and dusty weather condition. Other elements were economic challenges, such as poor household living conditions, neighbourhood deprivation, and socio-cultural elements, such as poor healthcare seeking behaviour, social mixing patterns, inadequate vaccination and vaccine hesitancy.
    Conclusion: As suggested by participants, there are potential environmental, socio-cultural and economic factors in the study area that might have been driving recurrent epidemics of cerebrospinal meningitis. In a bid to addressing this perennial challenge, governments at various levels supported by health development partners such as the World Health Organisation (WHO), United Nation Habitat, and United National Development Programme can use the findings of this study to design policies and programmes targeting these factors towards complementing other preventive and control strategies.
    MeSH term(s) Adult ; Aged ; Environment ; Epidemics ; Female ; Focus Groups ; Humans ; Male ; Meningitis, Meningococcal/epidemiology ; Middle Aged ; Nigeria/epidemiology ; Qualitative Research ; Recurrence ; Risk Factors ; Seasons ; Socioeconomic Factors
    Language English
    Publishing date 2018-12-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-018-6196-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Accelerated measles control in sub-Saharan Africa.

    Wiysonge, Charles Shey / Nomo, Emmanuel / Mawo, Jeanne Ngo-Ndjan / Ticha, Johnson M

    Lancet (London, England)

    2006  Volume 367, Issue 9508, Page(s) 394–395

    MeSH term(s) Africa South of the Sahara/epidemiology ; Humans ; Mass Vaccination/organization & administration ; Measles/epidemiology ; Measles/prevention & control ; Population Surveillance
    Language English
    Publishing date 2006-02-04
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(06)68133-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Progress Toward Poliomyelitis Eradication--Nigeria, January 2014-July 2015.

    Etsano, Andrew / Gunnala, Rajni / Shuaib, Faisal / Damisa, Eunice / Mkanda, Pascal / Ticha, Johnson M / Banda, Richard / Korir, Charles / Chevez, Ana Elena / Enemaku, Ogu / Corkum, Melissa / Davis, Lora B / Nganda, Gatei-Wa / Burns, Cara C / Wassilak, Steven G F / Vertefeuille, John F

    MMWR. Morbidity and mortality weekly report

    2015  Volume 64, Issue 32, Page(s) 878–882

    Abstract: Since the 1988 launch of global poliomyelitis eradication efforts, four of the six World Health Organization (WHO) regions have been certified polio-free. Nigeria is one of only three countries, along with Afghanistan and Pakistan, where transmission of ... ...

    Abstract Since the 1988 launch of global poliomyelitis eradication efforts, four of the six World Health Organization (WHO) regions have been certified polio-free. Nigeria is one of only three countries, along with Afghanistan and Pakistan, where transmission of wild poliovirus (WPV) has never been interrupted. During 2003-2013, northern Nigeria served as a reservoir for WPV reintroduction into 26 previously polio-free countries. In 2012, the Nigerian government launched a national polio eradication emergency plan to intensify efforts to interrupt WPV transmission. This report describes polio eradication activities and progress in Nigeria during January 2014-July 2015 and updates previous reports. No WPV cases have been reported to date in 2015, compared with a total of six cases reported during 2014. Onset of paralysis in the latest reported WPV type 1 (WPV1) case was July 24, 2014. Only one case of circulating vaccine-derived poliovirus type 2 (cVDPV2) has been reported to date in 2015, compared with 20 cVDPV2 cases during the same period in 2014. Pending final laboratory testing of 218 remaining specimens of 16,617 specimens collected since January 2015, Nigeria could be removed from the WHO list of polio-endemic countries in September 2015. Major remaining challenges to the national polio eradication program include sustaining political support and program funding in the absence of active WPV transmission, maintaining high levels of population immunity in hard-to-reach areas, and accessing children in security-compromised areas of the northeastern states.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Disease Eradication ; Humans ; Immunization Programs ; Incidence ; Infant ; Infant, Newborn ; Nigeria/epidemiology ; Poliomyelitis/epidemiology ; Poliomyelitis/prevention & control ; Poliovirus/isolation & purification ; Poliovirus Vaccines/administration & dosage ; Population Surveillance
    Chemical Substances Poliovirus Vaccines
    Language English
    Publishing date 2015-10-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 412775-4
    ISSN 1545-861X ; 0149-2195
    ISSN (online) 1545-861X
    ISSN 0149-2195
    DOI 10.15585/mmwr.mm6432a5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pediatric Bacterial Meningitis Surveillance in Nigeria From 2010 to 2016, Prior to and During the Phased Introduction of the 10-Valent Pneumococcal Conjugate Vaccine.

    Tagbo, Beckie N / Bancroft, Rowan E / Fajolu, Iretiola / Abdulkadir, Mohammed B / Bashir, Muhammad F / Okunola, Olusola P / Isiaka, Ayodeji H / Lawal, Namadi M / Edelu, Benedict O / Onyejiaka, Ngozi / Ihuoma, Chinonyerem J / Ndu, Florence / Ozumba, Uchenna C / Udeinya, Frances / Ogunsola, Folasade / Saka, Aishat O / Fadeyi, Abayomi / Aderibigbe, Sunday A / Abdulraheem, Jimoh /
    Yusuf, Adamu G / Sylvanus Ndow, Peter / Ogbogu, Philomena / Kanu, Chinomnso / Emina, Velly / Makinwa, Olajumoke J / Gehre, Florian / Yusuf, Kabir / Braka, Fiona / Mwenda, Jason M / Ticha, Johnson M / Nwodo, Dorothy / Worwui, Archibald / Biey, Joseph N / Kwambana-Adams, Brenda A / Antonio, Martin

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2019  Volume 69, Issue Suppl 2, Page(s) S81–S88

    Abstract: Background: Historically, Nigeria has experienced large bacterial meningitis outbreaks with high mortality in children. Streptococcus pneumoniae (pneumococcus), Neisseria meningitidis (meningococcus), and Haemophilus influenzae are major causes of this ... ...

    Abstract Background: Historically, Nigeria has experienced large bacterial meningitis outbreaks with high mortality in children. Streptococcus pneumoniae (pneumococcus), Neisseria meningitidis (meningococcus), and Haemophilus influenzae are major causes of this invasive disease. In collaboration with the World Health Organization, we conducted longitudinal surveillance in sentinel hospitals within Nigeria to establish the burden of pediatric bacterial meningitis (PBM).
    Methods: From 2010 to 2016, cerebrospinal fluid was collected from children <5 years of age, admitted to 5 sentinel hospitals in 5 Nigerian states. Microbiological and latex agglutination techniques were performed to detect the presence of pneumococcus, meningococcus, and H. influenzae. Species-specific polymerase chain reaction and serotyping/grouping were conducted to determine specific causative agents of PBM.
    Results: A total of 5134 children with suspected meningitis were enrolled at the participating hospitals; of these 153 (2.9%) were confirmed PBM cases. The mortality rate for those infected was 15.0% (23/153). The dominant pathogen was pneumococcus (46.4%: 71/153) followed by meningococcus (34.6%: 53/153) and H. influenzae (19.0%: 29/153). Nearly half the pneumococcal meningitis cases successfully serotyped (46.4%: 13/28) were caused by serotypes that are included in the 10-valent pneumococcal conjugate vaccine. The most prevalent meningococcal and H. influenzae strains were serogroup W and serotype b, respectively.
    Conclusions: Vaccine-type bacterial meningitis continues to be common among children <5 years in Nigeria. Challenges with vaccine introduction and coverage may explain some of these finding. Continued surveillance is needed to determine the distribution of serotypes/groups of meningeal pathogens across Nigeria and help inform and sustain vaccination policies in the country.
    MeSH term(s) Child, Preschool ; Cost of Illness ; Female ; Haemophilus influenzae/classification ; Hospitalization/statistics & numerical data ; Humans ; Infant ; Infant, Newborn ; Longitudinal Studies ; Male ; Meningitis, Bacterial/epidemiology ; Meningitis, Bacterial/mortality ; Meningitis, Bacterial/prevention & control ; Neisseria meningitidis/classification ; Nigeria ; Pneumococcal Vaccines/administration & dosage ; Sentinel Surveillance ; Serogroup ; Streptococcus pneumoniae/classification
    Chemical Substances 10-valent pneumococcal conjugate vaccine ; Pneumococcal Vaccines
    Language English
    Publishing date 2019-08-31
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciz474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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